Pharmacologic Treatment of Transplant Recipients Infected With SARS-CoV-2: Considerations Regarding Therapeutic Drug Monitoring and Drug–Drug Interactions
Conclusions: With this article, the authors inform the clinician about the potential interactions of experimental COVID-19 treatments with ISDs used in transplantation. Recommendations regarding therapeutic drug monitoring and dose adjustments in the context of COVID-19 are provided. (Source: Therapeutic Drug Monitoring)
Source: Therapeutic Drug Monitoring - May 20, 2020 Category: Drugs & Pharmacology Tags: Review Article Source Type: research

The New Direct-Acting Oral Anticoagulants Need to be Monitored!
No abstract available (Source: Therapeutic Drug Monitoring)
Source: Therapeutic Drug Monitoring - May 20, 2020 Category: Drugs & Pharmacology Tags: Editorial Source Type: research

Appreciating the Impact of Tacrolimus Sampling Time Deviations in Pediatric Patients With Nephrotic Syndrome
No abstract available (Source: Therapeutic Drug Monitoring)
Source: Therapeutic Drug Monitoring - May 20, 2020 Category: Drugs & Pharmacology Tags: Editorial Source Type: research

In Memoriam: Professor Folke Sjöqvist
No abstract available (Source: Therapeutic Drug Monitoring)
Source: Therapeutic Drug Monitoring - May 20, 2020 Category: Drugs & Pharmacology Tags: Obituary Source Type: research

Real-Time Therapeutic Drug Monitoring-Based Pharmacokinetic/Pharmacodynamic Optimization of Complex Antimicrobial Therapy in a Critically Ill Morbidly Obese Patient. Grand Round/A Case Study
Abstract: The authors present the case of a critically ill morbidly obese patient (body mass index, 51.2 kg/m2) who suffered from methicillin-resistant Staphylococcus epidermidis, and Candida albicans bloodstream infections. Initial treatment with caspofungin and daptomycin was deemed inappropriate, because blood cultures remained positive for both isolates after 14 days. The clinical pharmacological consultant suggested adding fluconazole and ceftobiprole to the ongoing antimicrobial therapy, and starting a real-time therapeutic drug monitoring program of daptomycin, ceftobiprole, and fluconazole, aimed at optimizing pl...
Source: Therapeutic Drug Monitoring - May 20, 2020 Category: Drugs & Pharmacology Tags: Grand Rounds Source Type: research