The Journal of Clinical Endocrinology and Metabolism This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Lessons from prospective longitudinal follow-up of a French APECED cohort
CONCLUSION: This first prospective cohort showed a high AIRE genotype variability, with two new gene variants. The prevalence of potentially life-threatening non-endocrine manifestations, was higher with systematic screening. These manifestations could, along with age-dependent B-cell lymphopenia, contribute to disease severity. Systematic screening for all the manifestations of the syndrome would allow earlier diagnosis, supporting vaccination, and targeted therapeutic approaches.PMID:38605470 | DOI:10.1210/clinem/dgae211 (Source: The Journal of Clinical Endocrinology and Metabolism)
Source: The Journal of Clinical Endocrinology and Metabolism - April 12, 2024 Category: Endocrinology Authors: Linda Humbert Emmanuelle Proust-Lemoine Sylvain Dubucquoi Elisabeth Helen Kemp Pascale Saugier-Veber Nicole Fabien Isabelle Raymond-Top Catherine Cardot-Bauters Jean-Claude Carel Maryse Cartigny Olivier Chabre Philippe Chanson Brigitte Delemer Christine D Source Type: research

Metabolic effects of testosterone added to intensive lifestyle intervention in older men with obesity and hypogonadism
CONCLUSION: In older men with obesity and hypogonadism, adding TRT for six months to LT does not result in further improved cardiometabolic profiles, and could potentially blunt some of the metabolic benefits induced by LT.PMID:38606934 | DOI:10.1210/clinem/dgae249 (Source: The Journal of Clinical Endocrinology and Metabolism)
Source: The Journal of Clinical Endocrinology and Metabolism - April 12, 2024 Category: Endocrinology Authors: Adrian M Gonzalez-Gil Yoann Barnouin Alessandra Celli Viola Viola Marcos D Villarreal Maria Liza Duremdes Nava Adam Sciuk Clifford Qualls Reina Armamento-Villareal Dennis T Villareal Source Type: research

Zoledronate after denosumab discontinuation: Is repeated administrations more effective than single infusion?
CONCLUSIONS: In patients with uncontrolled CTX levels after Dmab withdrawal, two ZOL infusions at 6 months apart do not prevent BMD loss and FX.PMID:38609157 | DOI:10.1210/clinem/dgae224 (Source: The Journal of Clinical Endocrinology and Metabolism)
Source: The Journal of Clinical Endocrinology and Metabolism - April 12, 2024 Category: Endocrinology Authors: Giorgia Grassi Alberto Ghielmetti Marta Zampogna Iacopo Chiodini Maura Arosio Giovanna Mantovani Cristina Eller Vainicher Source Type: research

Depression, Anxiety, and Risk of Metabolic Syndrome in Women With Polycystic Ovary Syndrome: A Longitudinal Study
CONCLUSIONS: Patients with PCOS and depression and/or anxiety have a high risk of developing MetSyn, with a stronger association between depression and MetSyn. Our findings highlight the urgent need for guideline-directed screening for depression and anxiety at time of diagnosis of PCOS as well as screening at subsequent visits to facilitate risk stratification for metabolic monitoring and early intervention in this high-risk group.PMID:38609160 | DOI:10.1210/clinem/dgae256 (Source: The Journal of Clinical Endocrinology and Metabolism)
Source: The Journal of Clinical Endocrinology and Metabolism - April 12, 2024 Category: Endocrinology Authors: Iris T Lee John Rees Shakira King Anne Kim Tess Cherlin Stefanie Hinkle Sunni L Mumford Anuja Dokras Source Type: research

Substituting carbohydrate at lunch for added protein increases fat oxidation during subsequent exercise in healthy males
CONCLUSION: Substituting carbohydrate for protein in a pre-exercise lunch increased fat oxidation, suppressed subjective and hormonal appetite, and reduced post-exercise energy intake.PMID:38609167 | DOI:10.1210/clinem/dgae237 (Source: The Journal of Clinical Endocrinology and Metabolism)
Source: The Journal of Clinical Endocrinology and Metabolism - April 12, 2024 Category: Endocrinology Authors: Tommy Slater William J A Mode Louise C Bonnard Cian Sweeney Mark P Funnell Harry A Smith John Hough Ruth M James Ian Varley Craig Sale James A Betts Lewis J James David J Clayton Source Type: research

Insulinemic and inflammatory dietary patterns show enhanced predictive potential for gestational diabetes mellitus risk
CONCLUSIONS: Utilizing both empirical dietary indexes, EDIP and EDIH, might offer a potentially more effective approach in preventing GDM when compared to solely focusing on adherence to the Mediterranean diet pattern.PMID:38609168 | DOI:10.1210/clinem/dgae238 (Source: The Journal of Clinical Endocrinology and Metabolism)
Source: The Journal of Clinical Endocrinology and Metabolism - April 12, 2024 Category: Endocrinology Authors: Ping Zu Haixia Wang Lei Zhang Haoran Bian Jingfeng Bian Nan Jiang Wei Luo Min Xu Jirong Xu Xiaomin Jiang Ruixue Tao Peng Zhu Source Type: research

Deep Learning Analysis with Gray Scale and Doppler Ultrasonography Images to Differentiate Graves' Disease
CONCLUSION: Machine learning models based on ultrasound and Doppler images showed promising results with high accuracy and sensitivity in differentiating GD from thyroiditis.PMID:38609169 | DOI:10.1210/clinem/dgae254 (Source: The Journal of Clinical Endocrinology and Metabolism)
Source: The Journal of Clinical Endocrinology and Metabolism - April 12, 2024 Category: Endocrinology Authors: Han-Sang Baek Jinyoung Kim Chaiho Jeong Jeongmin Lee Jeonghoon Ha Kwanhoon Jo Min Hee Kim Tae Seo Sohn Ihn Suk Lee Jong Min Lee Dong-Jun Lim Source Type: research

Impact of Distinct Anti-Androgen Exposures on the Plasma Metabolome in Feminizing Gender-Affirming Hormone Therapy
CONCLUSION: Our results suggest an anti-atherogenic signature in the plasma metabolome after the first six months of feminizing GAHT, with cyproterone acetate also reducing specific plasma amino acids. This study provides novel insight into the metabolic changes occurring across feminizing GAHT.PMID:38609170 | DOI:10.1210/clinem/dgae226 (Source: The Journal of Clinical Endocrinology and Metabolism)
Source: The Journal of Clinical Endocrinology and Metabolism - April 12, 2024 Category: Endocrinology Authors: Rebecca Shepherd Lachlan M Angus Toby Mansell Bridget Arman Bo Won Kim Katherine Lange David Burgner Jessica A Kerr Ken Pang Jeffrey D Zajac Richard Saffery Ada Cheung Boris Novakovic Source Type: research

Personalized non-invasive diagnostic algorithms based on urinary free cortisol in ACTH-dependant Cushing's syndrome
CONCLUSION: UFC accurately predicts EAS and can serve to define personalized and non-invasive diagnostic algorithms.PMID:38609171 | DOI:10.1210/clinem/dgae258 (Source: The Journal of Clinical Endocrinology and Metabolism)
Source: The Journal of Clinical Endocrinology and Metabolism - April 12, 2024 Category: Endocrinology Authors: Julie Lavoillotte Kamel Mohammedi Sylvie Salenave Raluca Maria Furnica Dominique Maiter Philippe Chanson Jacques Young Antoine Tabarin Source Type: research

Bisphosphonates Maintain BMD after Sequential Teriparatide and Denosumab in Premenopausal Women with Idiopathic Osteoporosis
CONCLUSION: BMD remained stable in women with PremenIOP who received bisphosphonates after sequential teriparatide-denosumab therapy.PMID:38605469 | DOI:10.1210/clinem/dgae240 (Source: The Journal of Clinical Endocrinology and Metabolism)
Source: The Journal of Clinical Endocrinology and Metabolism - April 12, 2024 Category: Endocrinology Authors: Mafo Kamanda-Kosseh Stephanie Shiau Sanchita Agarwal Ananya Kondapalli Ivelisse Colon Nayoung Kil Mariana Bucovsky Joan M Lappe Julie Stubby Elizabeth Shane Adi Cohen Source Type: research