Impact of Distinct Anti-Androgen Exposures on the Plasma Metabolome in Feminizing Gender-Affirming Hormone Therapy

CONCLUSION: Our results suggest an anti-atherogenic signature in the plasma metabolome after the first six months of feminizing GAHT, with cyproterone acetate also reducing specific plasma amino acids. This study provides novel insight into the metabolic changes occurring across feminizing GAHT.PMID:38609170 | DOI:10.1210/clinem/dgae226

Source: The Journal of Clinical Endocrinology and Metabolism - April 12, 2024 Category: Endocrinology Authors: Rebecca Shepherd Lachlan M Angus Toby Mansell Bridget Arman Bo Won Kim Katherine Lange David Burgner Jessica A Kerr Ken Pang Jeffrey D Zajac Richard Saffery Ada Cheung Boris Novakovic Source Type: research