Activity Pacing is Associated With Better and Worse Symptoms for Patients With Long-term Conditions
Conclusions: Some APQ-26 pacing themes were associated with worse symptoms and others with symptom improvement. Specifically, pacing themes involving adjusting/reducing activities were associated with worse symptoms, whereas pacing themes involving undertaking consistent activities were associated with improved symptoms. Future study will explore the causality of these associations to add clarification regarding the effects of pacing on patients’ symptoms. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - February 9, 2017 Category: Anesthesiology Tags: Original Articles Source Type: research

A Prospective Study of Predictors of Long-term Opioid Use Among Patients With Chronic Noncancer Pain
Discussion: The strongest predictors of long-term opioid use were not patient-related or medication-related factors, but expectations about using opioids in the future. Asking about such expectations may be the easiest way to identify patients likely to continue opioid use long-term. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - February 9, 2017 Category: Anesthesiology Tags: Original Articles Source Type: research

Epidural Against Systemic Analgesia: An International Registry Analysis on Postoperative Pain and Related Perceptions After Abdominal Surgery
Discussion: Regarding the pain intensity, satisfaction, and relatable side-effects, EA seems to be superior compared with systemic analgesia after AS. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - February 9, 2017 Category: Anesthesiology Tags: Original Articles Source Type: research

Prevalence of Chronic Neck Pain, Low Back Pain, and Knee Pain and Their Related Factors in Community-Dwelling Adults in Iran: A Population-based National Study
Conclusions: This is the first study investigating the prevalence of CNP, CLBP, and CKP in the national population of Iran. It shows some modifiable risk factors for CMP, and suggests that affordable planning for these risk factors can be valuable in preventing CMP globally. However, this is a cross-sectional study and future longitudinal studies in this field are necessary. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - January 7, 2017 Category: Anesthesiology Tags: Original Articles Source Type: research

Differences in Clinical Pain and Experimental Pain Sensitivity Between Asian Americans and Whites With Knee Osteoarthritis
Discussion: These findings add to the growing literature regarding ethnic and racial differences in clinical pain intensity and experimental pain sensitivity. Asian Americans in particular may be at risk for clinical pain and heightened experimental pain sensitivity. Further investigation is needed to identify the mechanisms underlying ethnic group differences in pain between Asian Americans and NHWs, and to ensure that ethnic group disparities in pain are ameliorated. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - January 7, 2017 Category: Anesthesiology Tags: Original Articles Source Type: research

Mindfulness is Associated With Increased Hedonic Capacity Among Chronic Pain Patients Receiving Extended Opioid Pharmacotherapy
Objectives: Chronic pain and long-term opioid use may lead to a persistent deficit in hedonic capacity, characterized by increased sensitivity to aversive states and insensitivity to natural rewards. Dispositional mindfulness has been linked with improved emotion regulation and pain coping. The aim of the current study was to examine associations between dispositional mindfulness, hedonic capacity, and pain-related interference in an opioid-using chronic pain sample. Methods: Data were obtained from a sample of 115 chronic pain patients on long-term opioid therapy (68% females, M age=48.3, SD=13.6) who completed the Five ...
Source: The Clinical Journal of Pain - January 7, 2017 Category: Anesthesiology Tags: Original Articles Source Type: research

Development and Preliminary Testing of a Screening Measure of Acceptance and Willingness in Relation to Pain, Fatigue, and Sadness in Chronic Pain
Conclusions: These results correspond with previous work and provide initial support for the validity of a single item screening measure of acceptance and willingness in chronic pain. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - January 7, 2017 Category: Anesthesiology Tags: Original Articles Source Type: research

High-density EMG Reveals Novel Evidence of Altered Masseter Muscle Activity During Symmetrical and Asymmetrical Bilateral Jaw Clenching Tasks in People With Chronic Nonspecific Neck Pain
Objectives: To characterize the distribution of masseter muscle activity and force control during bilateral jaw clenching tasks in people with chronic nonspecific neck pain, without an associated temporomandibular disorder. Methods: Twelve volunteers with nonspecific neck pain and 12 age-matched and sex-matched healthy individuals participated. Submaximal symmetrical and asymmetrical bilateral jaw clenching was performed with and without visual feedback of force. Force performance was assessed with indices of accuracy (mean distance, offset error) and precision (standard deviation, coefficient of variation of force). High...
Source: The Clinical Journal of Pain - January 7, 2017 Category: Anesthesiology Tags: Original Articles Source Type: research

Pulsed Electromagnetic Fields for Postsurgical Pain Management in Women Undergoing Cesarean Section: A Randomized, Double-Blind, Placebo-controlled Trial
Objectives: To evaluate the efficacy of pulsed electromagnetic field (PEMF) in relation to reducing postoperative pain, analgesic use, and wound healing in patients undergoing Cesarean section (C-section). Methods: This randomized, double-blind, placebo-controlled trial evaluated 72 women who underwent elective C-section. Thirty-six patients were assigned to the active-PEMF and 36 to the sham-PEMF groups. The participants were asked to report their pain intensity on a Visual Analog Scale (VAS) at 2, 4, 6, 12, and 24 hours and 2, 4, and 7 days after surgery. The amount of analgesics used was recorded. The surgical site was...
Source: The Clinical Journal of Pain - January 7, 2017 Category: Anesthesiology Tags: Original Articles Source Type: research

The Angle Labor Pain Questionnaire: Reliability, Validity, Sensitivity to Change, and Responsiveness During Early Active Labor Without Pain Relief
This study assessed the A-LPQ’s test-retest reliability during early active labor without pain relief. Methods: Two versions of the A-LPQ were randomly administered to laboring women during 2 test sessions separated by a 20-minute window. Participants were of mixed parity, contracting ≥3 minutes apart, cervical dilation ≤6 cm, and without pain relief. Changes in pain were rated using the Patient Global Impression of Change Scale. Overall pain intensity and pain coping were rated using the Numeric Rating Scale (NRS) and the Verbal Rating Scale (VRS) and the Pain Mastery Scale (PMS) respectively. A-LPQ test-rete...
Source: The Clinical Journal of Pain - January 7, 2017 Category: Anesthesiology Tags: Original Articles Source Type: research

Prediction of Postoperative Pain From Electrical Pain Thresholds After Laparoscopic Cholecystectomy
Objective: Early postoperative pain correlates to persisting pain, psychosocial distress, and delayed mobilization with thromboembolic and infectious complications. Electrical pain thresholds (EPT) have shown promising results in being able to predict postoperative pain, but the results are conflicting. The aim of this study was to test whether EPT levels can be used to predict the postoperative pain in patients of both sexes. Materials and Methods: One hundred eighty patients scheduled for laparoscopic cholecystectomy were included in this prospective clinical study. Individual levels of EPT were measured before surgery,...
Source: The Clinical Journal of Pain - January 7, 2017 Category: Anesthesiology Tags: Original Articles Source Type: research

Somatosensory Test Responses and Physical and Psychological Functioning of Children and Adolescents with Chronic Non-neuropathic Pain: An Exploratory Study
This study was designed to establish preliminary feasibility testing of a set of inherently benign somatosensory stimulus-response tests (to cutaneous and deep stimuli) for bedside or office evaluation of pain disorders in children and adolescents. Associations between, and the relative influence of, cutaneous somatosensory testing (SST) responses, deep SST responses, and psychological factors (depression, pain-related catastrophizing) on pain outcomes (worst pain intensity, pain-related disability) were considered. Methods: Sixty participants (6 to 18 y) were recruited from the pediatric chronic pain clinic. SST response...
Source: The Clinical Journal of Pain - January 7, 2017 Category: Anesthesiology Tags: Original Articles Source Type: research

Myofascial Trigger Points and Migraine-related Disability in Women With Episodic and Chronic Migraine
Conclusions: Women with episodic and chronic migraine had a similar number of TrPs. TrPs may be considered a trigger factor that can facilitate the onset of migraine or also can potentially be a promoting factor for pain once the migraine attack has started and hence may contribute to related disability. Nevertheless, we observed that the number of TrPs in the head and neck-shoulder muscles in an interictal state was not associated with the degree of migraine-related disability, suggesting a multifactorial nature of self-perceived disability in this population. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - January 7, 2017 Category: Anesthesiology Tags: Original Articles Source Type: research

Fulranumab in Patients With Pain Associated With Postherpetic Neuralgia and Postraumatic Neuropathy: Efficacy, Safety, and Tolerability Results From a Randomized, Double-blind, Placebo-controlled, Phase-2 Study
Discussion: Fulranumab did not demonstrate efficacy in either PHN or PTN patients, but was generally well-tolerated in this small underpowered and abbreviated study. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - January 7, 2017 Category: Anesthesiology Tags: Original Articles Source Type: research

Improvement in Pain After Lumbar Spine Surgery: The Role of Preoperative Expectations of Pain Relief
Conclusions: Pain is not uncommon after lumbar surgery and is associated with a network of clinical, surgical, and psychological variables. This study provides evidence that patients’ expectations about pain are an independent variable in this network. Because expectations are potentially modifiable this study supports addressing pain-related expectations with patients before surgery through discussions with surgeons and through formal preoperative patient education. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - January 7, 2017 Category: Anesthesiology Tags: Original Articles Source Type: research

A Meta-Analysis: Postoperative Pain Management in Colorectal Surgical Patients and the Effects on Length of Stay in an Enhanced Recovery After Surgery (ERAS) Setting
Conclusions: In an ERAS setting with regard to a colorectal patient population, the choice of modality for postoperative pain relief does not impact the length of hospital stay, pain, the time to the first bowel motion, or nausea. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - December 10, 2016 Category: Anesthesiology Tags: Review Articles Source Type: research

Are Passive Physical Modalities Effective for the Management of Common Soft Tissue Injuries of the Elbow?: A Systematic Review by the Ontario Protocol for Traffic Injury Management (OPTIMa) Collaboration
Discussion: Our review suggests that transcutaneous electrical nerve stimulation provides no added benefit to patients with lateral epicondylitis. The effectiveness of an elbow brace, shockwave therapy, or low-level laser therapy for the treatment of lateral epicondylitis is inconclusive. We found little evidence to inform the use of passive physical modalities for the management of elbow soft tissue injuries. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - December 10, 2016 Category: Anesthesiology Tags: Review Articles Source Type: research

Quadriceps Muscle Strength Correlates With Serum Vitamin D and Knee Pain in Knee Osteoarthritis
This study aimed to investigate the relationship between quadriceps muscle strength (QMS) and vitamin D in KOA. Methods: Patients with KOA aged 40 years and above were studied. QMS was assessed by the dynanometry method and serum 25-hydroxyvitamin D (25-OHD) by the ELISA method. Serum 25-OHD (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - December 10, 2016 Category: Anesthesiology Tags: Original Articles Source Type: research

Prediction of Acute Postoperative Pain Following Breast Cancer Surgery Using the Pain Sensitivity Questionnaire: A Cohort Study
Objectives: Previous studies have indicated that preoperative pain sensitivity correlates with postoperative pain intensity, and thus may be used to predict severe postoperative pain. Self-rating of pain sensitivity using the “Pain Sensitivity Questionnaire (PSQ)” may be an adjunct to these measures. Methods: We tested the predictive ability of the PSQ as well as experimental parameters of pain sensitivity and other known risk factors for acute pain in 198 patients scheduled for breast cancer surgery. A multivariable logistic regression model was created for the binary outcome “maximum pain>3 during t...
Source: The Clinical Journal of Pain - December 10, 2016 Category: Anesthesiology Tags: Original Articles Source Type: research

Persistent Breast Pain Among Women With Histories of Breast-conserving Surgery for Breast Cancer Compared With Women Without Histories of Breast Surgery or Cancer
This study compared persistent breast pain among women who received breast-conserving surgery for breast cancer and women without a history of breast cancer. Methods: Breast cancer survivors (n=200) were recruited at their first postsurgical surveillance mammogram (6 to 15 mo postsurgery). Women without a breast cancer history (n=150) were recruited at the time of a routine screening mammogram. All women completed measures of breast pain, pain interference with daily activities and intimacy, worry about breast pain, anxiety symptoms, and depression symptoms. Demographic and medical information were also collected. Result...
Source: The Clinical Journal of Pain - December 10, 2016 Category: Anesthesiology Tags: Original Articles Source Type: research

Pain is Associated With Poorer Grades, Reduced Emotional Well-Being, and Attention Problems in Adolescents
Objectives: The purpose of the present study was to determine whether pain is associated with specific aspects of academic performance, that is, poorer grades, and with factors critical to an adolescent’s academic performance, that is, decreased emotional well-being and attention problems. We hypothesized that the association between pain and school grades is mediated by emotional well-being and attention problems. Methods: In a cross-sectional study, we collected data from 2215 pupils, ages 12 to 13 years. Pain (no, occasional, and frequent), emotional well-being, and attention problems were measured with self-rati...
Source: The Clinical Journal of Pain - December 10, 2016 Category: Anesthesiology Tags: Original Articles Source Type: research

Using a Standardized Clinical Quantitative Sensory Testing Battery to Judge the Clinical Relevance of Sensory Differences Between Adjacent Body Areas
Conclusions: Sensory differences between neighboring body areas are statistically significant, reproducing prior knowledge. This has to be considered in scientific assessments where a small variation of the tested body areas may not be an option. However, the magnitude of these differences was below the difference in sensory parameters that is judged as abnormal, indicating a robustness of the QST instrument against protocol deviations with respect to the test area when using the method of comparison with a 95 % confidence interval of a reference dataset. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - December 10, 2016 Category: Anesthesiology Tags: Original Articles Source Type: research

Clinical Phenotyping of Youth With New-Onset Musculoskeletal Pain: A Controlled Cohort Study
Discussion: Clinical phenotyping of youth with new-onset musculoskeletal pain highlights factors relevant to the pain experience. Future research can examine the roles of these variables in predicting longitudinal risk for chronic pain and disability. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - December 10, 2016 Category: Anesthesiology Tags: Original Articles Source Type: research

Suicidal Ideation in Adolescents With and Without Chronic Pain
This study aimed to examine the rates and characteristics of SI in a clinical sample of adolescents with CP compared with youth without CP. We also examined the relationship between pain-related and psychosocial factors and SI in youth. Materials and Methods: Adolescents with (n=95) and without CP (n=91) completed self-reports of pain, functional disability, loneliness, family functioning, self-worth, and depressive symptoms including SI. Results: Rates of SI were not different in youth with CP when compared with those without ( , P>0.05). The content of suicidal thoughts also did not vary by group. Multivariate an...
Source: The Clinical Journal of Pain - December 10, 2016 Category: Anesthesiology Tags: Original Articles Source Type: research

Do Resting Plasma β-Endorphin Levels Predict Responses to Opioid Analgesics?
This study evaluated whether resting plasma β-endorphin (BE) levels predicted responses to an opioid analgesic, and whether chronic pain status or sex moderated these effects. Methods: Participants included 73 individuals with chronic low back pain (CLBP) and 88 pain-free controls, all using no daily opioid analgesics. Participants attended 2 identical laboratory sessions during which they received either intravenous morphine (0.08 mg/kg) or saline placebo, with blood samples obtained before drug administration to assay resting plasma BE levels. Once peak drug activity was achieved in each session, participants engag...
Source: The Clinical Journal of Pain - December 10, 2016 Category: Anesthesiology Tags: Original Articles Source Type: research

Characterizations of Temporal Postoperative Pain Signatures With Symbolic Aggregate Approximations
Discussion: SAX offers a feasible and effective framework for characterizing large-scale postoperative pain within the time domain. Stratification of SAX representations demonstrate unique temporal dynamic profiles on the basis of age group, sex, type of surgery, preoperative opioid use, and across PODs 1 to 7. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - December 10, 2016 Category: Anesthesiology Tags: Original Articles Source Type: research

Feasibility and Utility of the Individualized Hydrocodone Therapy Based on Phenotype, Pharmacogenetics, and Pharmacokinetic Dosing
No abstract available (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - November 9, 2016 Category: Anesthesiology Tags: Letters to the Editor Source Type: research

Assessment of Procedural Pain in Children Using Analgesia Nociception Index: A Pilot Study
Discussion: In this pilot study, ANI measurement seems relevant in pediatric procedural pain, across age. Further studies are needed to confirm these results. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - November 9, 2016 Category: Anesthesiology Tags: Original Articles Source Type: research

Assessing Pain Anxiety in Adolescents: Further Evidence for the Utility of the Child Pain Anxiety Symptoms Scale
Objectives: Emotional responses to pain are known to play an important role in the development and maintenance of pain. To better understand the role that pain anxiety plays in chronic pain, as well as to evaluate treatments that might treat it effectively, reliable and valid measures of pain anxiety are needed. Thus, the aim of this study was to provide additional evidence regarding the psychometric properties of the Child Pain Anxiety Symptoms Scale (CPASS) in a sample of adolescents. Methods: A total of 357 adolescents ages 12 to 19 years completed measures of pain anxiety (CPASS), pain-related catastrophizing (PCS-C),...
Source: The Clinical Journal of Pain - November 9, 2016 Category: Anesthesiology Tags: Original Articles Source Type: research

Neonatal Invasive Procedures Predict Pain Intensity at School Age in Children Born Very Preterm
Conclusions: In very preterm children, exposure to neonatal pain was related to altered pain self-ratings at school age, independent of other neonatal factors. Neonatal surgeries and concurrent psychosocial factors were also associated with pain ratings. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - November 9, 2016 Category: Anesthesiology Tags: Original Articles Source Type: research

Multiple Levels of Suffering: Discrimination in Health-Care Settings is Associated With Enhanced Laboratory Pain Sensitivity in Sickle Cell Disease
Discussion: Perceived discrimination within health-care settings was associated with pain facilitation. These findings suggest that discrimination may be related to increased central sensitization among SCD patients, and more broadly that health-care social environments may interact with pain pathophysiology. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - November 9, 2016 Category: Anesthesiology Tags: Original Articles Source Type: research

Isometric Exercise Above but not Below an Individual’s Pain Threshold Influences Pain Perception in People With Lateral Epicondylalgia
Discussion: Individuals with lateral epicondylalgia demonstrated increased pain intensity after an acute bout of isometric exercise performed at an intensity above, but not below, their individual pain threshold. Further investigation is needed to determine whether measurement of an individual’s exercise induced pain threshold may be important in reducing symptom flares associated with exercise. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - November 9, 2016 Category: Anesthesiology Tags: Original Articles Source Type: research

The Association Between Chronic Pain and Cardiac Disease: A Cross-sectional Population Study
This study aims to examine the possibility of an independent association between these 2 variables. Methods: We applied logistic regression analysis to data from 8596 adults surveyed in a population study of the health of the population of England. The association between cardiac disease (angina and/or myocardial infarction) and chronic pain (pain lasting>3 months) was explored, taking account of 10 potentially confounding variables including the regular use of nonsteroidal anti-inflammatory drugs. Results: Participants reporting chronic pain (n=3023) were more likely to experience cardiac disease than those without p...
Source: The Clinical Journal of Pain - November 9, 2016 Category: Anesthesiology Tags: Original Articles Source Type: research

Does Magnesium Sulfate as an Adjuvant of Local Anesthetics Facilitate Better Effect of Perineural Nerve Blocks?: A Meta-analysis of Randomized Controlled Trials
Objectives: To investigate the efficacy and safety of magnesium sulfate as an adjuvant of local anesthetics in perineural nerve blocks. Materials and Methods: Randomized controlled trials studying the effect and safety of magnesium sulfate in perineural nerve blocks were retrieved from online databases. The mean difference (MD), risk ratio, and their corresponding 95% confidence intervals (CIs) were calculated using RevMan 5.3 statistical software. Results: Seven trials evaluating 493 patients were included. The pooled results from our meta-analysis showed that a combination of magnesium sulfate and local anesthetics in ...
Source: The Clinical Journal of Pain - November 9, 2016 Category: Anesthesiology Tags: Original Articles Source Type: research

The Location of Peak Upper Trapezius Muscle Activity During Submaximal Contractions is not Associated With the Location of Myofascial Trigger Points: New Insights Revealed by High-density Surface EMG
Aim: To apply topographical mapping of the electromyography (EMG) amplitude recorded from the upper trapezius muscle to evaluate the distribution of activity and the location of peak activity during a shoulder elevation task in participants with and without myofascial pain and myofascial trigger points (MTrP) and compare this location with the site of the MTrP. Materials and Methods: Thirteen participants with myofascial pain and MTrP in the upper trapezius muscle and 12 asymptomatic individuals participated. High-density surface EMG was recorded from the upper trapezius muscle using a matrix of 64 surface electrodes alig...
Source: The Clinical Journal of Pain - November 9, 2016 Category: Anesthesiology Tags: Original Articles Source Type: research

The Effect of Medicinal Cannabis on Pain and Quality-of-Life Outcomes in Chronic Pain: A Prospective Open-label Study
The objective of this prospective, open-label study was to determine the long-term effect of medicinal cannabis treatment on pain and functional outcomes in participants with treatment-resistant chronic pain. Patients and Methods: The primary outcome was the change in the pain symptom score on the S-TOPS (Treatment Outcomes in Pain Survey—Short Form) questionnaire at the 6-month follow-up in an intent-to-treat population. Secondary outcomes included the change in S-TOPS physical, social, and emotional disability scales, the pain severity, and pain interference on the Brief Pain Inventory, sleep problems, and the cha...
Source: The Clinical Journal of Pain - November 9, 2016 Category: Anesthesiology Tags: Original Articles Source Type: research

Rumination, Magnification, and Helplessness: How do Different Aspects of Pain Catastrophizing Relate to Pain Severity and Functioning?
This study represents the first to evaluate the functioning of these subscales in a large, diagnostically heterogeneous sample of chronic pain patients. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - November 9, 2016 Category: Anesthesiology Tags: Original Articles Source Type: research

Differing Psychologically Derived Clusters in People With Chronic Low Back Pain are Associated With Different Multidimensional Profiles
Discussion: Clinical implications relating to presentations of each cluster are postulated. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - November 9, 2016 Category: Anesthesiology Tags: Original Articles Source Type: research

Central Sensitization: A Clinical Conundrum
No abstract available (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - October 5, 2016 Category: Anesthesiology Tags: Letter to the Editor Source Type: research

Duloxetine in Painful Diabetic Neuropathy: A Systematic Review
Conclusions: Duloxetine has a beneficial effect over placebo. Nevertheless, the evidence of superiority of duloxetine over pregabalin and amitriptyline should be explored further as there was only 1 trial for each category. Provided majority of the PDN patients share cardiovascular complications, use of duloxetine will be a good option for treating pain associated with PDN over amitriptyline. Future randomized controlled trials should be designed keeping this in mind. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - October 5, 2016 Category: Anesthesiology Tags: Review Articles Source Type: research

Does Evidence Support the Use of Neural Tissue Management to Reduce Pain and Disability in Nerve-related Chronic Musculoskeletal Pain?: A Systematic Review With Meta-Analysis
Objectives: In nerve-related chronic musculoskeletal (MS) disorders, neural tissue management is used to relieve pain by balancing the relative movement of neural tissues and their surrounding tissues. To date, there has not been any review evaluating the magnitude of this treatment effect in nerve-related chronic MS pain. The aim of this review was to compare pain and disability in individuals with nerve-related chronic MS pain who were treated with neural tissue management with those who received minimal or other treatment approaches. Methods: Searches of 8 major electronic databases were conducted, and data on pain and...
Source: The Clinical Journal of Pain - October 5, 2016 Category: Anesthesiology Tags: Review Articles Source Type: research

A Systematic Review of Knowledge Translation (KT) in Pediatric Pain: Focus on Health Care Providers
Discussion: KT programs vary in quality and impact. Although several successful programs have been developed, many studies include a high risk of bias due to study quality. Evidence-based KT program implementation and a focus on sustainability of outcomes must be given greater consideration in the field of pediatric pain. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - October 5, 2016 Category: Anesthesiology Tags: Review Articles Source Type: research

Efficacy of Cabbage Leaf Wraps in the Treatment of Symptomatic Osteoarthritis of the Knee: A Randomized Controlled Trial
Conclusions: CLWs are more effective for knee OA than UC, but not compared with diclofenac gel. Therefore, they might be recommended for patients with OA of the knee. Further research is warranted. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - October 5, 2016 Category: Anesthesiology Tags: Original Articles Source Type: research

Central Poststroke Pain Can Occur With Normal Sensation
Discussion: CPSP was present in 20.7% of the stroke patients. Spinothalamic tract dysfunction may not be necessary for the development of CPSP, and it can also be seen with normal spinothalamic sensation. The location of the stroke, its type and quality, and the severity of CPSP were not related. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - October 5, 2016 Category: Anesthesiology Tags: Original Articles Source Type: research

Does Topical Lidocaine Reduce the Pain Associated With the Insertion of Nasal Continuous Positive Airway Pressure Prongs in Preterm Infants?: A Randomized, Controlled Pilot Trial
Discussion: Our data suggest that topical lidocaine did not reduce the pain associated with the insertion of nCPAP prongs in preterm infants. However, the trends for lower PIPP scores in the lidocaine group and the effect sizes for lidocaine on PIPP scores and salivary cortisol were large enough so that a large-scale randomized clinical trial is warranted to confirm or refute our results. Such a study should compare 2 or more active pain interventions during nCPAP application, rather than evaluating a single intervention versus placebo or no treatment. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - October 5, 2016 Category: Anesthesiology Tags: Original Articles Source Type: research

Development and Validation of the Behavioral Avoidance Test—Back Pain (BAT-Back) for Patients With Chronic Low Back Pain
In this study, we developed and validated a Behavioral Avoidance Test (BAT) for chronic low back pain (CLBP) patients with the aim of assessing pain-related avoidance behavior by direct observation. Materials and Methods: The BAT-Back was administered to a group of CLBP patients (N=97) and pain-free controls (N=31). Furthermore, pain, pain-related fear, disability, catastrophizing, and avoidance behavior were measured using self-report instruments. Reliability was assessed with intraclass correlation coefficient and Cronbach α. Validity was assessed by examining correlation and regression analysis. Results: The int...
Source: The Clinical Journal of Pain - October 5, 2016 Category: Anesthesiology Tags: Original Articles Source Type: research

Acute Low Back Pain: Differential Somatosensory Function and Gene Expression Compared With Healthy No-Pain Controls
Discussion: Acute LBP participants showed selective pain sensitivity enhancement and differential gene expression profiles compared with pain-free controls. Further research to characterize pain-associated somatosensory changes in the context of altered mRNA expression levels may provide insight on the molecular underpinnings of maladaptive chronic pain. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - October 5, 2016 Category: Anesthesiology Tags: Original Articles Source Type: research

The Efficacy of Pregabalin in the Treatment of Prediabetic Neuropathic Pain
We report the results of a pilot, enrichment-design, placebo-controlled crossover trial of pregabalin for the treatment of prediabetic small-fiber neuropathic pain. Methods: Individuals with impaired fasting glucose or impaired glucose tolerance and neuropathic pain were evaluated according to UTAH Early Neuropathy Scale (UENS), Quantitative Sensory Testing, and intraepidermal nerve fiber density (IENFD). Symptoms were graded according to the Numeric Rating Scale (NRS). Individuals who responded to the administration of placebo were not eligible. Pregabalin was initiated at a dose of 75 mg qid and tapered up to 300 mg bid...
Source: The Clinical Journal of Pain - October 5, 2016 Category: Anesthesiology Tags: Original Articles Source Type: research

Randomized Sham-controlled Double-Blind Multicenter Clinical Trial to Ascertain the Effect of Percutaneous Radiofrequency Treatment for Sacroiliac Joint Pain: Three-month Results
Objectives: To investigate the effect of a percutaneous radiofrequency (RF) heat lesion compared with a sham procedure, applied to the lateral branches of L5, S1, S2, S3, and S4 nerve roots. Materials and Methods: Sixty patients aged 18 years and above with a medical history and physical examination suggestive for sacroiliac joint pain and a reduction of 2 or more on a numerical rating scale (NRS, 0 to 10) after a sacroiliac joint test block were included in this study. Treatment group: percutaneous RF heat lesion at the lateral branches of S1, S2, S3, and S4 nerve roots and the posterior ramus dorsalis of L5; sham group:...
Source: The Clinical Journal of Pain - October 5, 2016 Category: Anesthesiology Tags: Original Articles Source Type: research