The Relationship Between Clinical and Quantitative Measures of Pain Sensitization in Knee Osteoarthritis
This study examines the relationship between quantitative sensory testing (QST) and clinical measures of pain sensitization in people with knee OA. Methods: A secondary analysis of data from 134 participants with knee OA was performed. Clinical measures included: manual tender point count (MTPC), the Central Sensitization Inventory (CSI) to capture centrally mediated comorbidities, number of painful sites on a body chart, and neuropathic pain-like symptoms assessed using the modified PainDetect Questionnaire. Relationships between clinical measures and QST measures of pressure pain thresholds (PPTs), temporal summation,...
Source: The Clinical Journal of Pain - April 7, 2020 Category: Anesthesiology Tags: Original Articles Source Type: research

Assessment of Somatosensory and Psychosocial Function of Patients With Trigeminal Nerve Damage
Objective: The present study assessed somatosensory changes related to trigeminal nerve damage using extensive evaluation tools and assessed the effect of such damage on the patients’ psychosocial status and quality of life compared with healthy participants. Methods: In 37 patients with intraorally or extraorally presenting trigeminal nerve damage diagnosed as painful or nonpainful posttraumatic trigeminal neuropathy, psychophysical tests like quantitative sensory testing (QST) and qualitative sensory testing and the electrophysiological “nociceptive-specific” blink reflex were performed. The patients and 20 he...
Source: The Clinical Journal of Pain - April 7, 2020 Category: Anesthesiology Tags: Original Articles Source Type: research

Adherence to Consolidated Standards of Reporting Trials (CONSORT) Guidelines for Reporting Safety Outcomes in Trials of Medical Cannabis and Cannabis-based Medicines for Chronic Noncancer Pain: A Systematic Review
Discussion: Better harms assessment and reporting are needed in chronic pain cannabinoid trials. Improvements may be achieved through: expanded education/knowledge translation increased research regulation by ethics boards, funding agencies and journals, and greater emphasis on safety assessment and reporting throughout research training. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - March 12, 2020 Category: Anesthesiology Tags: Review Article Source Type: research

Factors Associated With Minimum Effective Volume of Lidocaine 1.5% for Sciatic Nerve Blocks
The objectives of this study were to investigate the correlations between the minimum effective volume (MEV) of lidocaine 1.5% for an ultrasound-guided popliteal sciatic nerve block and individual factors including the cross-sectional nerve area, sex, age, body mass index, and the depth of the sciatic nerve and to evaluate the safety of combined femoral and sciatic nerve blocks by monitoring the plasma concentration of local anesthetics. Methods: Forty patients received combined single-shot femoral and continuous sciatic nerve blocks. The femoral nerve block was performed with an in-plane technique and 15 mL of lidoca...
Source: The Clinical Journal of Pain - March 12, 2020 Category: Anesthesiology Tags: Original Articles Source Type: research

Targeting Occipital Headache Pain: Preliminary Data Supporting an Alternative Approach to Occipital Nerve Block
This study evaluated the efficacy and validity of an alternative, single skin insertion, paresthesia-based approach to block both the greater and lesser occipital nerve. Materials and Methods: Patients with a clinical diagnosis of occipital headache were included in this study. External landmarks of the cervical spinous process and ipsilateral tragus were used to predict the location of the OA pulse at the superior nuchal line. Alternative ONB technique was used to block both the greater and lesser occipital nerves using single skin insertion and paresthesia confirmation. Demographic data, preprocedure, and postprocedur...
Source: The Clinical Journal of Pain - March 12, 2020 Category: Anesthesiology Tags: Original Articles Source Type: research

Development of a Measure of Nociception for Patients With Severe Brain Injury
Discussion: The results provide evidence that the Brain Injury Nociception Assessment Measure (BINAM) is reliable and feasible to administer. It can assess the intensity of nociception largely independent of the level of consciousness. Further research is warranted on the impact of BINAM use on the care of patients with severe traumatic brain injury. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - March 12, 2020 Category: Anesthesiology Tags: Original Articles Source Type: research

Clinical Scenarios for Which Cervical Mobilization and Manipulation Are Considered by an Expert Panel to Be Appropriate (and Inappropriate) for Patients With Chronic Neck Pain
Conclusions: Clinical guidelines for CNP should include information on the clinical scenarios for which cervical mobilization and manipulation were found inappropriate, including those with red flags, and others involving major neurological findings if previous manual therapy was unfavorable. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - March 12, 2020 Category: Anesthesiology Tags: Original Articles Source Type: research

Efficacy of Nalbuphine as an Adjuvant to Ropivacaine in Ultrasound-guided Supraclavicular Brachial Block: A Prospective Randomized Controlled Study
Conclusions: Nalbuphine is an effective adjuvant to 0.5% ropivacaine in ultrasound-guided supraclavicular BPB. The dosage of 10 mg improves the quality of the anesthesia with less incidence of side effects. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - March 12, 2020 Category: Anesthesiology Tags: Original Articles Source Type: research

Electromyographic Comparison of the Efficacy of Ultrasound-guided Suprainguinal and Infrainguinal Fascia Iliaca Compartment Block for Blockade of the Obturator Nerve in Total Knee Arthroplasty: A Prospective Randomized Controlled Trial
Conclusions: Suprainguinal FICB significantly increased the incidence of successful obturator nerve block and significantly decreased fentanyl consumption 24 hours after TKA compared with infrainguinal FICB. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - March 12, 2020 Category: Anesthesiology Tags: Original Articles Source Type: research

The Complex Interplay of Pain, Depression, and Anxiety Symptoms in Patients With Chronic Pain: A Network Approach
This study aimed to analyze the associations among depressive and anxiety and pain symptoms in patients diagnosed with chronic pain. Materials and Methods: Four hundred fifty-four inpatients who were consecutively admitted in a multimodal 3-week treatment in a tertiary, psychosomatic university clinic completed 25 items from the Brief Pain Inventory and the Hospital Anxiety and Depression Scale at baseline and after treatment termination. Associations among symptoms were explored by network analyses using the graphical least absolute shrinkage and selection operator to estimate their partial correlations, whereas Extend...
Source: The Clinical Journal of Pain - March 12, 2020 Category: Anesthesiology Tags: Original Articles Source Type: research

The Interplay of Parent and Child Coping Responses in Understanding Child Functioning in the Context of Living With a Parent With or Without Chronic Pain
Discussion: The current findings demonstrated that child functioning was associated with maternal and child pain catastrophizing, but only in children of mothers without CP. No evidence was found in support of maternal pain coping responses as vulnerability or protective factors in the context of parental CP. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - March 12, 2020 Category: Anesthesiology Tags: Original Articles Source Type: research

Serum Inflammatory Markers in Patients With Knee Osteoarthritis: A Proteomic Approach
This study aimed to assess serum levels of 92 markers involved in inflammatory pathways in patients with knee osteoarthritis (KOA) and evaluate their possible associations with the clinical pain intensity. Materials and Methods: Serum samples were collected from 127 KOA patients and 39 healthy participants with no knee pain. Each serum sample was analyzed for 92 inflammatory markers using the Proximity Extension Array (PEA) technology. Clinical pain intensity was assessed using a Visual Analog Scale, and patients completed the Knee Injury and Osteoarthritis Outcome Score (KOOS) questionnaire. Results: Fifteen markers...
Source: The Clinical Journal of Pain - March 12, 2020 Category: Anesthesiology Tags: Original Articles Source Type: research

Further Examination of the Pain Stages of Change Questionnaires Among Chronic Low Back Pain Patients: Long-Term Predictive Validity of Pretreatment and Posttreatment Change Scores and Stability of Posttreatment Scores
No abstract available (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - February 12, 2020 Category: Anesthesiology Tags: Letter to the Editor Source Type: research

Enhanced Recovery After Surgery (ERAS): A Perspective Review of Postoperative Pain Management Under ERAS Pathways and Its Role on Opioid Crisis in the United States
The objective of this study was to review the current scientific evidence on the role of Enhanced Recovery After Surgery (ERAS) implementations in reducing postoperative opioid consumption and their potential association with the risk reduction for long-term opioid use, physical opioid dependency, and opioid addiction. Methods: A literature search was conducted using the following medical subject heading keywords: “postoperative pain,” “postoperative pain management,” “multimodal analgesia,” “ERAS,” “Enhanced Recovery,” “opioid-free analgesia,” or “opioid crisis.” Discussion: Identificatio...
Source: The Clinical Journal of Pain - February 12, 2020 Category: Anesthesiology Tags: Review Article Source Type: research

Cosyntropin for the Treatment of Refractory Postdural Puncture Headache in Pediatric Patients: A Retrospective Review
This study suggests that while further research is warranted, cosyntropin is a potential alternative to epidural blood patch for pediatric patients with postdural puncture headache who fail conservative management. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - February 12, 2020 Category: Anesthesiology Tags: Original Articles Source Type: research