Comparative Effectiveness of Landmark-guided Greater Occipital Nerve (GON) Block at the Superior Nuchal Line Versus Ultrasound-guided GON Block at the Level of C2: A Randomized Clinical Trial (RCT)
Conclusions: Ultrasound-guided GONBs may provide superior pain reduction at 4 weeks when compared with landmark-based GONBs for patients with occipital neuralgia or cervicogenic headache. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - March 11, 2022 Category: Anesthesiology Tags: Original Articles Source Type: research

Clinical Efficacy of Perioperative Intravenous Dexmedetomidine and Lidocaine Combined Infusion for Thyroidectomy: A Prospective, Randomized, Double-Blind, Placebo-Controlled Trial
Objectives: The aim of this study was to evaluate the efficacy of perioperative dexmedetomidine (DEX) combined with lidocaine intravenous infusion on relieving postoperative pain and improving recovery for patients undergoing thyroidectomy. Materials and Methods: A total of 138 patients undergoing thyroidectomy with general anesthesia were randomly divided into 4 groups: lidocaine (1.5 mg/kg bolus followed by 2 mg/kg/h infusion) in the group L, DEX (0.5 µg/kg) in the group D, lidocaine (same as the group L) with DEX (0.5 µg/kg) in the group L+D, and placebo as normal saline in the group C. All drugs we...
Source: The Clinical Journal of Pain - March 11, 2022 Category: Anesthesiology Tags: Original Articles Source Type: research

The Mediating Role of Illness Cognitions in the Relationship Between Caregiving Demands and Caregivers’ Psychological Adjustment
Discussion: The results suggest that illness cognitions play an important role in the psychological adjustment of partners. Enhancing acceptance of the illness and reducing feelings of helplessness could form the basis of interventions aiming at promoting psychological adjustment in partners, especially when it is difficult to reduce the demands. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - March 11, 2022 Category: Anesthesiology Tags: Original Articles Source Type: research

Effects of Gabapentin Enacarbil on Postoperative Pain After Hip and Knee Arthroplasty: A Placebo-controlled Randomized Trial
Discussion: We did not identify statistically significant or clinically meaningful differences in our primary and secondary outcomes related to perioperative use of gabapentin enacarbil in patients having primary hip or knee arthroplasties. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - March 11, 2022 Category: Anesthesiology Tags: Original Articles Source Type: research

A Standardized Assessment of Movement-evoked Pain Ratings Is Associated With Functional Outcomes in Older Adults With Chronic Low Back Pain
This study investigated whether a novel MeP paradigm contributed to self-reported and performance-based function in older adults with CLBP. Materials and Methods: This secondary analysis includes baseline data from 230 older adults with CLBP in the context of a prospective cohort study. The Repeated Chair Rise Test, Six Minute Walk Test, and Stair Climbing Test were used to elicit pain posttest LBP ratings were aggregated to yield the MeP variable. Self-reported and performance-based function were measured by the Late Life Function and Disability Index (LLFDI) scaled function score and Timed Up-and-Go Test (TUG), re...
Source: The Clinical Journal of Pain - March 11, 2022 Category: Anesthesiology Tags: Original Articles Source Type: research

Impact of Transversus Abdominis Plane Block With Bupivacaine or Ropivacaine Versus Intrathecal Morphine on Opioid-related Side Effects After Cesarean Delivery: A Meta-analysis of Randomized Controlled Trials
Objectives: Intrathecal morphine (ITM) is frequently associated with side effects such as postoperative nausea and vomiting (PONV) and pruritus. The aim of this meta-analysis was to compare the impact of transversus abdominis plane (TAP) block versus ITM on side effects following cesarean delivery. Materials and Methods: PubMed, Embase, Web of Science, and CENTRAL were searched for randomized controlled trials that compared TAP with ITM for cesarean delivery. The primary outcomes were opioid-related side effects. The secondary outcomes included pain scores, opioid consumption, patient satisfaction, and time to t...
Source: The Clinical Journal of Pain - February 9, 2022 Category: Anesthesiology Tags: Review Articles Source Type: research

More Than 1 in 3 Patients With Chronic Low Back Pain Continue to Use Opioids Long-term After Spinal Fusion: A Systematic Review
Discussion: Overall, opioid use is not reported in the majority of lumbar fusion trials. Patients may expect a reduced need for opioid-based pain management after surgery, but the limited data available suggests long-term use is common. Lack of consistent reporting of these outcomes limits definitive conclusions regarding the efficacy of spinal fusion for reducing long-term opioid. Patient decisions about undergoing surgery may be altered if they had realistic expectations about rates of postsurgical opioid use. Spine surgery trials should track opioid utilization out to a minimum of 6 months after surgery as a core ou...
Source: The Clinical Journal of Pain - February 9, 2022 Category: Anesthesiology Tags: Review Articles Source Type: research

Are Measures of Physical Function of the Neck Region Associated With Poor Prognosis Following a Whiplash Trauma?: A Systematic Review
The objective of this study was to synthesize the current evidence regarding the predictive ability of measures of physical function (PF) of the neck region and perceived PF on prognosis following a whiplash injury. Materials and Methods: Electronic databases were searched by 2 independent reviewers up to July 2020, including MEDLINE, EMBASE, CINAHL, PsycINFO, Scopus, and Web of Science as well as gray literature. Eligible studies were selected by 2 reviewers who then extracted and assessed the quality of evidence. Observational cohort studies were included if they involved participants with acute whiplash-associate...
Source: The Clinical Journal of Pain - February 9, 2022 Category: Anesthesiology Tags: Review Articles Source Type: research

Cost-effectiveness of Multidisciplinary Interventions for Chronic Low Back Pain: A Narrative Review
This study encourages additional rigorous economic evaluations of multidisciplinary models for chronic pain management. Economic evaluations that enable extrapolating costs and effects of multidisciplinary programs beyond the time horizon of clinical trials may be more informative for clinicians and health administrators. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - February 9, 2022 Category: Anesthesiology Tags: Review Articles Source Type: research

A Pilot Randomized Controlled Trial of Virtual Reality Distraction to Reduce Procedural Pain During Subcutaneous Port Access in Children and Adolescents With Cancer
Discussion: VR was feasible and acceptable to implement as an intervention during SCP access. Preliminary effectiveness results indicate that VR may reduce distress and distress compared with iPad distraction. These data will inform design of a future full-scale randomized controlled trial. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - February 9, 2022 Category: Anesthesiology Tags: Original Articles Source Type: research

Exploring the Preference for Fatigue-avoidance Goals as a Mediator Between Pain Catastrophizing, Functional Impairment, and Walking Behavior in Women With Fibromyalgia
Discussion: The present study may help clarify the connection between the factors that stop individuals with FM from implementing beneficial behaviors such as walking, and thus, allowing for the design of psychological interventions that seek to maintain physical functioning despite experiencing fatigue. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - February 9, 2022 Category: Anesthesiology Tags: Original Articles Source Type: research

Establishing Clinical Cut-points on the Pediatric PROMIS-Pain Interference Scale in Youth With Abdominal Pain
Discussion: Results suggest the PPPI is a valid measure with clinically meaningful cut-points to assess pain-related interference in youth with abdominal pain. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - February 9, 2022 Category: Anesthesiology Tags: Original Articles Source Type: research

Are Reports of Pain, Disability, Quality of Life, Psychological Factors, and Central Sensitization Related to Outcomes of Quantitative Sensory Testing in Patients Suffering From Chronic Whiplash Associated Disorders?
Conclusion: QST outcomes relate to psychological constructs, rather than to self-reported pain intensity and distribution. Local hyperalgesia was found in individuals with CWAD, but no differences in endogenous pain facilitation nor inhibition. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - February 9, 2022 Category: Anesthesiology Tags: Original Articles Source Type: research

Classification of Individual Pain Response Trajectories Following Medically Indicated Heel Lances in Preterm Infants During Their NICU Admission
This study used existing clinical trial data (NCT01561547) that evaluated the efficacy of kangaroo care and sucrose for infant pain control. Pain was measured using the Premature Infant Pain Profile at 30, 60, 90, and 120 seconds following a heel lance. Group-based trajectory modeling was used to classify pain response in this 2 minute period. Results: A total of 236 infants with median gestational age of 33 weeks contributed 610 procedures. A model with 5 trajectory classes best fit the data. Three trajectories were stable over time at different levels of intensity from low-mild to low-moderate pain. One trajectory...
Source: The Clinical Journal of Pain - February 9, 2022 Category: Anesthesiology Tags: Original Articles Source Type: research

Clinical Relevance of Epidural Steroid Injections on Lumbosacral Radicular Syndrome-related Symptoms: Systematic Review and Meta-Analysis
No abstract available (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - January 16, 2022 Category: Anesthesiology Tags: Letter to the Editor Source Type: research