Mast Cell Stabilizer (Ketotifen) in Fibromyalgia: Phase 1 Randomized Controlled Clinical Trial
Discussion: The study results question whether skin mast cells play a major role in the pathogenesis of FM. However, given the role of mast cells in peripheral and central nociception, and the minimal side effects of ketotifen, a randomized clinical trial using increasing doses of ketotifen may be warranted. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - August 8, 2015 Category: Anesthesiology Tags: Original Articles Source Type: research

Pain Management in Neonatal Intensive Care: Evaluation of the Compliance With Guidelines
Conclusions: Although the majority of pain assessments suggested comfortable patients, there is room for improvement with respect to reassessments after adjustment of analgesic/sedative treatment. Some protocol violations such as oversedation in palliative patients are acceptable but should be well documented. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - August 8, 2015 Category: Anesthesiology Tags: Original Articles Source Type: research

Evaluation of Health Plan Interventions to Influence Chronic Opioid Therapy Prescribing
Discussion: Following initiatives implemented to alter physician prescribing practices and norms, mean opioid dose prescribed to COT patients declined more in intervention than control practices. Physicians reported more conservative beliefs regarding opioid prescribing immediately after completing an online course in 2011, but the course was not associated with additional reductions in mean daily opioid dose prescribed by physicians completing the course. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - August 8, 2015 Category: Anesthesiology Tags: Original Articles Source Type: research

Is HIV Painful? An Epidemiologic Study of the Prevalence and Risk Factors for Pain in HIV-infected Patients
Discussion: Pain, and notably foot/ankle pain, is common among adults living with prevalent HIV and is associated with substantial morbidity and health care utilization. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - August 8, 2015 Category: Anesthesiology Tags: Original Articles Source Type: research

Baseline Variation in Use of VA/DOD Clinical Practice Guideline Recommended Opioid Prescribing Practices Across VA Health Care Systems
Discussion: In 2010, guideline-recommended practices for opioid prescribing were variably used across VA health care systems. Efforts to disseminate practices used at high-performing sites, and increase consistency of use of recommended practices across patients and facilities should be considered to improve pain management and reduce adverse events. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - August 8, 2015 Category: Anesthesiology Tags: Original Articles Source Type: research

The Effect of Pain on Physical Functioning After Breast Cancer Treatment: Development and Validation of an Assessment Tool
Discussion: The present scales displayed good psychometric qualities, and may be used to evaluate the impact of specific sequelae after breast cancer treatment on physical functioning, as well as to monitor and target interventions to optimize pain treatment and rehabilitation. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - August 8, 2015 Category: Anesthesiology Tags: Original Articles Source Type: research

Contemporary Pain Management in Elderly Patients After Hip Fracture Surgery: Cross-sectional Analyses at Baseline of a Randomized Controlled Trial
Conclusions: Overall, the levels of pain reported by this cohort are acceptable although approximately 10% to 15% had higher than reasonable levels of pain. This study provides an insight into pain assessment and management by identifying certain patient subtypes who are vulnerable to undertreatment of pain. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - August 8, 2015 Category: Anesthesiology Tags: Original Articles Source Type: research

Leading a Horse to Water: Facilitating Registration and Use of a Prescription Drug Monitoring Program
Objectives: Prescription Drug Monitoring Programs (PDMPs) can help inform patient management, coordinate care, and identify drug safety risks, abuse, or diversion. However, many clinicians are not registered to use these systems, and use may be suboptimal. We sought to describe outreach efforts in 1 state (Oregon); quantify uptake of system use; identify barriers; and identify potential system improvements. Methods: Program reports of outreach efforts and operational metrics provided rates of registration and use. A statewide survey identified perceived barriers and potential improvements from users and nonusers of the sys...
Source: The Clinical Journal of Pain - August 8, 2015 Category: Anesthesiology Tags: Original Articles Source Type: research

Modeling the Trajectory of Analgesic Demand Over Time After Total Knee Arthroplasty Using the Latent Curve Analysis
Conclusions: Latent curve analysis provided valuable information about how analgesic demand after TKA changed over time and how patient characteristics affected its trajectory. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - August 8, 2015 Category: Anesthesiology Tags: Original Articles Source Type: research

Genetic Polymorphisms in the Dopamine Receptor 2 Predict Acute Pain Severity After Motor Vehicle Collision
This study tested the hypothesis that genetic variants in the genes encoding dopamine receptor 2 (DRD2) and the dopamine active transporter (SLC6A3) influence acute pain severity after motor vehicle collision. Materials and Methods: European Americans presenting to the emergency department after motor vehicle collision were recruited. Overall pain intensity in emergency department was assessed using a 0 to 10 numeric rating scale. DNA was extracted from blood samples and genotyping of single-nucleotide polymorphisms (SNPs) in the DRD2 and SLC6A3 gene was performed. Results: A total of 948 patients completed evaluation. Aft...
Source: The Clinical Journal of Pain - August 8, 2015 Category: Anesthesiology Tags: Original Articles Source Type: research

Intranasal Oxytocin Administration is Associated With Enhanced Endogenous Pain Inhibition and Reduced Negative Mood States
This study examined whether the administration of intranasal oxytocin was associated with pain sensitivity, endogenous pain inhibitory capacity, and negative mood states. Materials and Methods: A total of 30 pain-free, young adults each completed 3 laboratory sessions on consecutive days. The first session (baseline) assessed ischemic pain sensitivity, endogenous pain inhibition via conditioned pain modulation (CPM), and negative mood using the Profile of Mood States. CPM was tested on the dominant forearm and ipsilateral masseter muscle using algometry (test stimulus) and the cold pressor task (conditioning stimulus; nond...
Source: The Clinical Journal of Pain - August 8, 2015 Category: Anesthesiology Tags: Original Articles Source Type: research

Predictive Factors Associated With Success and Failure for Calmare (Scrambler) Therapy: A Multicenter Analysis
Conclusions: A neuropathic or mixed neuropathic-nociceptive pain condition was associated with a positive treatment outcome. Investigators should consider these findings when developing selection criteria in clinical trials designed to determine the efficacy of Calmare therapy. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - July 11, 2015 Category: Anesthesiology Tags: Original Articles Source Type: research

Effects of Experimental Tooth Clenching on Pain and Intramuscular Release of 5-HT and Glutamate in Patients With Myofascial TMD
This study investigated the effects of experimental tooth clenching on the levels of 5-HT, glutamate, pyruvate, and lactate, as well as on blood flow and pain intensity, in the masseter muscles of M-TMD patients. Methods: Fifteen patients with M-TMD and 15 pain-free controls participated. Intramuscular microdialysis was performed to collect 5-HT, glutamate, pyruvate, and lactate and to assess blood flow. Two hours after the insertion of a microdialysis catheter, participants performed a 20-minute repetitive tooth clenching task (50% of maximal voluntary contraction). Pain intensity was measured throughout. Results: A signi...
Source: The Clinical Journal of Pain - July 11, 2015 Category: Anesthesiology Tags: Original Articles Source Type: research

Natural Variation in Testosterone is Associated With Hypoalgesia in Healthy Women
Discussion: Although future research is needed to replicate and extend these findings to clinical populations (ie, chronic pain, premenstrual dysphoric disorder), results from the present study indicate that menstrual phase-related changes in sex hormones have minimal influence on experimental pain. However, individual differences in testosterone may play a protective role against pain in healthy women. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - July 11, 2015 Category: Anesthesiology Tags: Original Articles Source Type: research

National Dissemination of Cognitive-Behavioral Therapy for Chronic Pain in Veterans: Therapist and Patient-level Outcomes
Discussion: Training in and implementation of CBT-CP in the VA health care system were associated with significant increases in therapist competencies to deliver CBT-CP and improvements in several domains for Veteran patients. Results support the feasibility and effectiveness of broad dissemination of CBT-CP in routine, nonpain specialty settings. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - July 11, 2015 Category: Anesthesiology Tags: Original Articles Source Type: research

Patients With Neck Pain are Less Likely to Improve if They Experience Poor Sleep Quality: A Prospective Study in Routine Practice
Discussion: NP is less likely to improve in patients with poorer SQ, irrespective of age, sex, catastrophizing, depression, or treatments prescribed for NP. Future studies should confirm these results with more severely impaired patients. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - July 11, 2015 Category: Anesthesiology Tags: Original Articles Source Type: research

A Debate on the Proposition that Self-report is the Gold Standard in Assessment of Pediatric Pain Intensity
Discussion: We conclude that self-report, when available, can be considered a primary source of evidence about pain intensity. However, it cannot be treated as an unquestioned gold standard. Instead, hierarchical or bundled approaches should be used, taking into account self-report as well as the many individual and contextual factors that influence pain including clinical history, patient preferences, and response to previous treatments. Alternate models are presented to guide further practice and research. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - July 11, 2015 Category: Anesthesiology Tags: Original Articles Source Type: research

Preoperative State Anxiety, Acute Postoperative Pain, and Analgesic Use in Persons Undergoing Lower Limb Amputation
Objectives: The current study examined the relationship between preoperative anxiety and acute postoperative phantom limb pain (PLP), residual limb pain (RLP), and analgesic medication use in a sample of persons undergoing lower limb amputation. Materials and Methods: Participants included 69 adults admitted to a large level 1 trauma hospital for lower limb amputation. Participants’ average pain and anxiety during the previous week were assessed before amputation surgery. RLP, PLP, and analgesic medication use were measured on each of the 5 days following amputation surgery. Results: Results of partial-order correlat...
Source: The Clinical Journal of Pain - July 11, 2015 Category: Anesthesiology Tags: Original Articles Source Type: research

Parenting in the Context of Chronic Pain: A Controlled Study of Parents With Chronic Pain
This study aims to describe what adults with chronic pain experience in their role as parents, utilizing quantitative and qualitative methods. The first aim was to compare parents with chronic pain to parents without chronic pain on perceptions of their adolescent’s pain, parental response to pain, and catastrophizing beliefs about pain. The study also examined predictors of parental protective behaviors, and examined whether these associations differed by study group. Materials and Methods: Parents with chronic pain (n=58) and parents without chronic pain (n=72) participated, and completed questionnaire measures of ...
Source: The Clinical Journal of Pain - July 11, 2015 Category: Anesthesiology Tags: Original Articles Source Type: research

Exploring Attentional Bias for Real-World, Pain-related Information in Chronic Musculoskeletal Pain Using a Novel Change Detection Paradigm
This study is the first to show individuals with chronic pain possess attentional biases for pain-related information presented as part of complex, real-world scenes. Possible future research includes the use of real-world scenes in visual-search paradigms modifying attentional biases, and exploration into the relations and effects of combined cognitive biases (eg, attention, memory, and interpretation) in chronic pain. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - July 11, 2015 Category: Anesthesiology Tags: Original Articles Source Type: research

Patterns of Use and Health Expenses Associated With Triptans Among Adults With Migraines
Discussion: The study suggested that socioeconomic factors were associated with triptan use in migraineurs. Higher total and migraine-related health expenses were observed in triptan users. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - July 11, 2015 Category: Anesthesiology Tags: Original Articles Source Type: research

Pros and Cons of Opioids and Prediction of Sustained Use Provides Long-awaited Answers With Clarity
No abstract available (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - June 10, 2015 Category: Anesthesiology Tags: Letters to the Editor Source Type: research

Avoidance or Incapacitation: A Discussion on Definition and Validity of Objective Measures of Avoidance, Persistence, and Overactivity
No abstract available (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - June 10, 2015 Category: Anesthesiology Tags: Letters to the Editor Source Type: research

Improving the Multidisciplinary Treatment of Chronic Pain by Stimulating Body Awareness: A Cluster-randomized Trial
Conclusions: No clinical meaningful differences were found between treatment conditions in the primary outcome measures health-related quality of life and disability. However, this is the first long-term RCT that has shown that PMT improves BA in patients with chronic pain and shows good effect size and a significant decrease for catastrophizing. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - June 10, 2015 Category: Anesthesiology Tags: Original Articles Source Type: research

Validity of a Paradigm for Low Back Pain Symptom Development During Prolonged Standing
This study provides evidence that symptoms experienced during the standing paradigm are similar to symptoms experienced by people with LBP and, thus, provides support for the validity of the paradigm. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - June 10, 2015 Category: Anesthesiology Tags: Original Articles Source Type: research

Experimental Pelvic Pain Impairs the Performance During the Active Straight Leg Raise Test and Causes Excessive Muscle Stabilization
This study aimed to bypass the influence of decreased SIJ stability on the ASLR test by investigating the effect of experimental pelvic pain and hyperalgesia on the outcome of the ASLR test. Methods: Thirty-four healthy participants took part in this randomized crossover study. Pelvic pain was induced by injecting hypertonic saline into the long posterior sacroiliac ligament. Isotonic saline was injected on the contralateral side as control. Pain intensity was assessed on an electronic visual analogue scale. The Likert scores of difficulty performing the ASLR test and simultaneous electromyography of trunk and thigh muscle...
Source: The Clinical Journal of Pain - June 10, 2015 Category: Anesthesiology Tags: Original Articles Source Type: research

Living Life With My Child’s Pain: The Parent Pain Acceptance Questionnaire (PPAQ)
Conclusions: The PPAQ is a valid measure of parent pain acceptance and may provide valuable insights into parent responses to child pain and the ways in which parent acceptance influences child outcomes. Clinical implications and suggestions for future research are discussed. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - June 10, 2015 Category: Anesthesiology Tags: Original Articles Source Type: research

What Do People Who Score Highly on the Tampa Scale of Kinesiophobia Really Believe?: A Mixed Methods Investigation in People With Chronic Nonspecific Low Back Pain
Discussion: The TSK may be better described as a measure of the “beliefs that painful activity will result in damage and/or increased suffering and/or functional loss.” (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - June 10, 2015 Category: Anesthesiology Tags: Original Articles Source Type: research

Effectiveness and Safety of Transdermal Buprenorphine Versus Sustained-release Tramadol in Patients With Moderate to Severe Musculoskeletal Pain: An 8-Week, Randomized, Double-Blind, Double-Dummy, Multicenter, Active-controlled, Noninferiority Study
Conclusions: Our results suggest that BTDS is a good therapeutic option for patients experiencing chronic musculoskeletal pain of moderate to severe intensity that is insufficiently controlled by nonsteroidal anti-inflammatory drugs. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - June 10, 2015 Category: Anesthesiology Tags: Original Articles Source Type: research

Does Change Occur for the Reasons We Think It Does? A Test of Specific Therapeutic Operations During Cognitive-Behavioral Treatment of Chronic Pain
Discussion: Change with CBT may occur both by theory-specified mechanisms and general mechanisms. However, the results provide the most support for a General Mechanism model in which changes on coping skills have spreading effects on the use of other coping skills. Significant relationships between some skill changes and indexes of patient-therapist working alliance and outcome expectations suggest that nonspecific factors also play a role in treatment-related changes in the use of pain coping strategies. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - June 10, 2015 Category: Anesthesiology Tags: Original Articles Source Type: research

Reliability is Necessary but Far From Sufficient: How Might the Validity of Pain Ratings be Improved?
No abstract available (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - June 10, 2015 Category: Anesthesiology Tags: Editorial Source Type: research

Publicly Available Online Educational Videos Regarding Pediatric Needle Pain: A Scoping Review
The objectives of this scoping review were to: (1) identify publicly available educational videos on needle pain management; and (2) evaluate the content of these videos. Methods: Reviewers screened publicly available educational videos on pediatric needle pain management available on YouTube and Google using a broad-based search strategy. Videos were categorized using the CRAAP Test: Current, Relevant, from a trustworthy source (Authority), Accurate and evidence-based, and for what Purpose does the source exist. Results: Twenty-five relevant, educational videos were identified. The intended audience for most videos was pa...
Source: The Clinical Journal of Pain - May 6, 2015 Category: Anesthesiology Tags: Special Topics Series Source Type: research

Development, Content Validity, and User Review of a Web-based Multidimensional Pain Diary for Adolescent and Young Adults With Sickle Cell Disease
Conclusion: A multidimensional web-based electronic pain diary for adolescents and young adults with SCD has been developed and content validity and initial end-user reviews have been completed. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - May 6, 2015 Category: Anesthesiology Tags: Special Topics Series Source Type: research

Using Health Information Technology to Improve Adherence to Opioid Prescribing Guidelines in Primary Care
Discussion: Implementation of an opioid dashboard led to increased adherence to certain opioid practice guidelines and a decline in COT. This may be attributable to more efficient team-based pain management facilitated by the dashboard and increased transparency of opioid prescription practices. Health Information Technology solutions such as clinical dashboards can increase adherence to practice guidelines. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - May 6, 2015 Category: Anesthesiology Tags: Special Topics Series Source Type: research

Integrating Virtual Reality With Activity Management for the Treatment of Fibromyalgia: Acceptability and Preliminary Efficacy
This study focuses on exploring the use of Virtual Reality (VR) as an adjunct to the activity management component. The aim of this study is to present the results of a small-sized randomized controlled trial to test the preliminary efficacy and acceptability of this component. Materials and Methods: The final sample was composed of 61 women diagnosed with FMS according to the American College of Rheumatology. The sample was randomly allocated to 2 conditions: VR treatment and treatment as usual. Results: Participants in the VR condition achieved significant improvements in the primary outcome: disability measured with the...
Source: The Clinical Journal of Pain - May 6, 2015 Category: Anesthesiology Tags: Special Topics Series Source Type: research

“There’s a Pain App for That”: Review of Patient-targeted Smartphone Applications for Pain Management
Discussion: Currently available pain self-management apps for patients are simplistic, lack the involvement of health care professionals in their development, and have not been rigorously tested for effectiveness on pain-related health outcomes. There is a need to develop and test theoretically and evidence-based apps to better support patients with accessible pain care self-management. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - May 6, 2015 Category: Anesthesiology Tags: Special Topics Series Source Type: research

Piloting a Text Message–based Social Support Intervention for Patients With Chronic Pain: Establishing Feasibility and Preliminary Efficacy
Discussion: These findings establish the feasibility of collecting daily pain data using a mobile tracking App and provide significant implications and insight into a nuanced approach to reducing the daily experience of pain through mobile technology, especially because of its accessibility. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - May 6, 2015 Category: Anesthesiology Tags: Special Topics Series Source Type: research

Changes in Coping, Pain, and Activity After Cognitive-Behavioral Training: A Randomized Clinical Trial for Pediatric Sickle Cell Disease Using Smartphones
We examined the outcomes of a cognitive-behavioral therapy (CBT) intervention for pain in pediatric sickle cell disease (SCD) using smartphones as a novel delivery method. Materials and Methods: Forty-six children with SCD received CBT coping skills training using a randomized, waitlist control design. The intervention involved a single session of CBT training and home-based practice using smartphones for 8 weeks. Pre-post questionnaires between the randomized groups were used to evaluate changes in active psychological coping and negative thinking using the Coping Strategies Questionnaire. Daily diaries completed by the f...
Source: The Clinical Journal of Pain - May 6, 2015 Category: Anesthesiology Tags: Special Topics Series Source Type: research

Impact of an Acceptance Facilitating Intervention on Patients’ Acceptance of Internet-based Pain Interventions: A Randomized Controlled Trial
Conclusions: Patients with chronic pain display a relatively low acceptance of Internet-based psychological pain interventions, which can be substantially increased by a short informational video. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - May 6, 2015 Category: Anesthesiology Tags: Special Topics Series Source Type: research

Comparison of an Online Mindfulness-based Cognitive Therapy Intervention With Online Pain Management Psychoeducation: A Randomized Controlled Study
Conclusions: The results of the study provide evidence that although there were equivalent changes across outcomes of interest for participants in both conditions over time, the MIA program showed a number of unique benefits. However, the level of participant attrition in the study highlighted a need for further attention to participant engagement with online chronic pain programs. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - May 6, 2015 Category: Anesthesiology Tags: Special Topics Series Source Type: research

Individualized Guided Internet-delivered Cognitive-Behavior Therapy for Chronic Pain Patients With Comorbid Depression and Anxiety: A Randomized Controlled Trial
Discussion: One-year follow-up showed maintenance of improvements. We conclude that an individualized guided internet-delivered treatment based on cognitive-behavior therapy can be effective for persons with chronic pain comorbid emotional distress. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - May 6, 2015 Category: Anesthesiology Tags: Special Topics Series Source Type: research

Testing the Feasibility of DARWeb: An Online Intervention for Children With Functional Abdominal Pain and Their Parents
Discussion: DARWeb has been shown to be a feasible intervention, and it seems to be well designed. However, some improvements need to be considered based on the experiences of these participating families, and further research should be conducted to test its efficacy. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - May 6, 2015 Category: Anesthesiology Tags: Special Topics Series Source Type: research

A Systematic Review of Technology-assisted Self-Management Interventions for Chronic Pain: Looking Across Treatment Modalities
This article is a systematic review of technology-assisted self-management interventions for chronic nonheadache, noncancer pain in adults. We examined 3 treatment modalities: telephone, interactive voice response, and Internet. Electronic searches of OVID MEDLINE, OVID PsychINFO, and the Cochrane Database of Systematic Reviews were conducted. Forty-four articles including 9890 participants were reviewed. Results: Across modalities, the existing evidence suggests that technology-assisted psychological interventions are efficacious for improving self-management of chronic pain in adults. All modalities have been shown to pr...
Source: The Clinical Journal of Pain - May 6, 2015 Category: Anesthesiology Tags: Special Topics Series Source Type: research

Innovative Delivery of Pain Management Interventions: Current Trends and Future Progress
No abstract available (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - May 6, 2015 Category: Anesthesiology Tags: Editorial Source Type: research

Painful Restless Legs Syndrome: A Severe, Burning Form of the Disease
Discussion: Painful RLS appears to be a severe, “burning” subtype of RLS, and could be a distinct disease or a clinical variant in a sensations continuum. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - April 9, 2015 Category: Anesthesiology Tags: Original Articles Source Type: research

Randomized Placebo-controlled Trial of Sucrose Analgesia on Neonatal Skin Blood Flow and Pain Response During Heel Lance
Conclusions: Increased SBF assessed by LDI is a pain response among term neonates after routine heel lance, which was not completely attenuated by oral sucrose administration. Increased SBF is associated with NIPS scores. Sucrose analgesic efficacy evidenced by decreased NIPS scores for the sucrose group. Association of SBF with NIPS scores suggests that LDI is potentially useful for assessing newborn procedural pain. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - April 9, 2015 Category: Anesthesiology Tags: Original Articles Source Type: research

Onset of Analgesia and Efficacy of Ibuprofen Sodium in Postsurgical Dental Pain: A Randomized, Placebo-controlled Study Versus Standard Ibuprofen
The objective of the current study was to compare the efficacy and onset of analgesia of this new formulation with standard IBU tablets after a single dose. Materials and Methods: Patients (N=316) with at least moderate baseline postsurgical dental pain were randomized to 400 mg IBUNa, Advil (IBUAdv), Motrin (IBUMot), or placebo. Primary endpoints were time-weighted sum of pain relief (PR) and pain intensity differences over 8 hours (SPRID 0-8) and time to onset of meaningful pain relief (TMPR) measured by the double-stopwatch method. Results: SPRID 0-8 was significantly greater for IBUNa and the other active treatments ve...
Source: The Clinical Journal of Pain - April 9, 2015 Category: Anesthesiology Tags: Original Articles Source Type: research

An Adaptive Role for Negative Expected Pain in Patients With Neuropathic Pain
Discussion: In neuropathic pain patients whose pain does not respond to therapy, high levels of expected pain may relate to relatively lower catastrophizing scores by shifting focus away from futile attempts at “curing” pain toward focusing on achievement of more realistic personal goals. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - April 9, 2015 Category: Anesthesiology Tags: Original Articles Source Type: research

A 2-center Comparative Study on Tonic Versus Burst Spinal Cord Stimulation: Amount of Responders and Amount of Pain Suppression
Conclusions: Burst seems to be significantly better than tonic stimulation. It can rescue an important amount of nonresponders to tonic stimulation and can further improve pain suppression in responders to tonic stimulation. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - April 9, 2015 Category: Anesthesiology Tags: Original Articles Source Type: research

Sex Differences in Psychological Response to Pain in Patients With Fibromyalgia Syndrome
Discussion: The study findings suggest that women and men with FMS may think about and cope with pain somewhat differently, and may therefore benefit from different types of psychosocial pain intervention. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - April 9, 2015 Category: Anesthesiology Tags: Original Articles Source Type: research