Human rights violations among men who have sex with men and transgender people in South Africa
Conclusion: Our findings demonstrate the feasibility of documenting HRVs among MSM and TG people within HIV prevention programmes. Men who have sex with men and TG people should be systematically screened for HRVs and linked to legal or other services.Contribution: Our findings present data on the nature of HRVs in 10 districts outside of the large urban centres where research documenting the lived experiences of MSM, TG people and other key populations is traditionally conducted in South Africa. Such data contribute to addressing the gap in the literature o n the needs of MSM and TG people in South Africa caused by the ...
Source: Southern African Journal of HIV Medicine - January 23, 2023 Category: African Health Authors: Raymond Chimatira Source Type: research

Late-onset efavirenz toxicity: A descriptive study from Pretoria, South Africa
Conclusion: Late-onset efavirenz toxicity typically presented with ataxia and encephalopathy, but psychosis can be the presenting feature. The outcome after withdrawal was good, but the mortality of 10.0% is concerning. Recent changes in guidelines favour dolutegravir, but many patients remain on efavirenz, a nd awareness of the condition is vital.What this study adds: This large, single-centre study contributes to the limited data of HIV-positive patients with late-onset efavirenz toxicity and emphasises its ongoing relevance in clinical practice. (Source: Southern African Journal of HIV Medicine)
Source: Southern African Journal of HIV Medicine - January 12, 2023 Category: African Health Authors: Lyneshree Munsami Source Type: research

Table of Contents Vol 23, No 1 (2022)
No abstract available. (Source: Southern African Journal of HIV Medicine)
Source: Southern African Journal of HIV Medicine - December 31, 2022 Category: African Health Authors: Editorial Office Source Type: research

Acknowledgement to reviewers
No abstract available. (Source: Southern African Journal of HIV Medicine)
Source: Southern African Journal of HIV Medicine - December 14, 2022 Category: African Health Authors: Editorial Office Source Type: research

Effect of obesity on dolutegravir exposure in Black Southern African adults living with HIV
Conclusion: Dolutegravir exposure was marginally lower in participants with obesity, but this is not clinically significant. Our findings suggest that there is no need to dose adjust dolutegravir in people with obesity. (Source: Southern African Journal of HIV Medicine)
Source: Southern African Journal of HIV Medicine - December 13, 2022 Category: African Health Authors: Enkosi Mondleki Source Type: research

Effect of a ward-based outreach team and adherence game on retention and viral load suppression
Conclusion: This study demonstrated that an adherence game intervention could help keep PLWH in care.What this study adds: Evidence that interventions, especially Games, could improve retention in care. (Source: Southern African Journal of HIV Medicine)
Source: Southern African Journal of HIV Medicine - December 7, 2022 Category: African Health Authors: Sanele Ngcobo Source Type: research

COVID-19 and HIV viral load suppression in children and adolescents in Durban, South Africa
Conclusion: Viral load suppression for children and adolescents were not negatively affected by COVID-19. A trend of decrease in VL testing predated COVID-19.What this study adds: Evidence presented that HIV VL testing and suppression rates in children and adolescents in a high burden setting were sustained through the COVID pandemic. (Source: Southern African Journal of HIV Medicine)
Source: Southern African Journal of HIV Medicine - December 2, 2022 Category: African Health Authors: Asandile Mathamo Source Type: research

Erratum: Southern African HIV Clinicians Society 2022 guideline for the management of sexually transmitted infections: Moving towards best practice
No abstract available. (Source: Southern African Journal of HIV Medicine)
Source: Southern African Journal of HIV Medicine - November 24, 2022 Category: African Health Authors: Remco P.H. Peters Source Type: research

Experiences in receiving financial incentives to access HIV care in Johannesburg, South Africa
Conclusion: Financial incentivisation can facilitate engagement in the HIV care continuum through providing support to people living with HIV.What this study adds: This study complements the body of research that explores the feasibility of using incentives and which of them may be most beneficial in encouraging patients with HIV to enter into and sustain HIV care. (Source: Southern African Journal of HIV Medicine)
Source: Southern African Journal of HIV Medicine - November 17, 2022 Category: African Health Authors: Sara Rachel Schlehr Source Type: research

Comparative performance of cardiovascular risk prediction models in people living with HIV
Conclusion: Overall, predicted CVD risk is low in this population. Compared to D:A:D 2010, CVD risk estimated by the FHS-CVD model showed similar overall results for risk classification. With the exception of the D:A:D model, all other risk prediction models classified fewer people to be at high estimated CVD risk. Prospective studies are needed to develop and validate CVD risk algorithms in people living with HIV in sub-Saharan Africa. (Source: Southern African Journal of HIV Medicine)
Source: Southern African Journal of HIV Medicine - November 15, 2022 Category: African Health Authors: Irtiza S. Tahir Source Type: research

Incidence of hepatitis C virus infection among people living with HIV: An Egyptian cohort study
Conclusion: Egyptian HIV-infected patients show a high incidence rate of HCV infection especially among those who have a history of IDU. Accordingly, attention should be paid for prevention, screening and timely treatment of HCV in patients infected with HIV.What this study adds: The demonstration of a high HCV infection incidence rate among HIV-infected patients and shows the need for screening and prevention in this population. (Source: Southern African Journal of HIV Medicine)
Source: Southern African Journal of HIV Medicine - November 9, 2022 Category: African Health Authors: Fatma Elrashdy Source Type: research

Oral pre-exposure prophylaxis uptake, adherence, and adverse events among South African men who have sex with men and transgender women
Conclusion: Many MSM and TGW initiated and maintained PrEP, demonstrating that PrEP can be successfully delivered to South African MSM and TGW in diverse programmatic contexts. Biologic adherence measures suggest MSM and TGW may experience challenges taking PrEP regularly. Counselling for coping with side eff ects and motivating daily pill taking is recommended to support South African MSM and TGW in achieving protection with PrEP. (Source: Southern African Journal of HIV Medicine)
Source: Southern African Journal of HIV Medicine - November 8, 2022 Category: African Health Authors: Linda-Gail Bekker Source Type: research

COP27 Climate Change Conference: Urgent action needed for Africa and the world
No abstract available. (Source: Southern African Journal of HIV Medicine)
Source: Southern African Journal of HIV Medicine - November 4, 2022 Category: African Health Authors: Lukoye Atwoli Source Type: research

HIV viral load suppression before and after COVID-19 in Kinshasa and Haut Katanga, Democratic Republic of the Congo
Conclusion: Viral loads did not deteriorate despite pandemic-induced changes in HIV services such as the expansion of multi-month dispensing (MMD), which may have played a protective role regardless of the general negative impacts of response to the COVID-19 crises on communities and individuals.What this study adds: This research capitalises on the natural experiment of COVID-19-related changes in HIV services and provides new practice-relevant research evidence. (Source: Southern African Journal of HIV Medicine)
Source: Southern African Journal of HIV Medicine - October 28, 2022 Category: African Health Authors: Gulzar H. Shah Source Type: research

Weight gain in children from birth to 10 years on antiretroviral treatment
Conclusion: Antiretroviral treatment improved weight and height gain in CLHIV, but the interpretations of weight gain differed significantly between the WHO chart and HIV-specific weight gain curves. Population- and treatment-specific references could improve weight monitoring in CLHIV and assist in the timeo us identification of malnutrition. (Source: Southern African Journal of HIV Medicine)
Source: Southern African Journal of HIV Medicine - October 28, 2022 Category: African Health Authors: Janine Scholtz Source Type: research