HIV testing at birth: Are we getting it right?
Conclusion: The majority of HIV-exposed infants received a PCR test at birth; however, the clinic is below the national target (90%) for HIV testing. A record-keeping system of infants’ visits does not exist at MUCPP CHC, making it impossible to determine whether HIV-positive infants were started on antiret roviral treatment. (Source: Southern African Journal of HIV Medicine)
Source: Southern African Journal of HIV Medicine - June 26, 2019 Category: African Health Authors: Chant é Bisschoff Source Type: research

A case report of untreatable HIV infection in Harare, Zimbabwe
Conclusion: This is the first documented case of multiclass resistance to the four available ART classes in Zimbabwe. The development and transmission of multiclass HIV drug resistance in resource limited settings has potential to undo the gains of national ART programs. There is need to ensure optimum adhere nce to ART even in the era of DTG. (Source: Southern African Journal of HIV Medicine)
Source: Southern African Journal of HIV Medicine - June 26, 2019 Category: African Health Authors: Cleophas Chimbetete Source Type: research

Self-reported risky sexual practices among adolescents and young adults in Botswana
Conclusions: Self-reported risky sexual practices of adolescents and young adults in Botswana differed significantly between males and females. Gender-specific risky sexual practices highlight the importance of developing tailored HIV prevention programming. (Source: Southern African Journal of HIV Medicine)
Source: Southern African Journal of HIV Medicine - June 25, 2019 Category: African Health Authors: Unoda Chakalisa Source Type: research

‘At this [adherence] club, we are a family now’: A realist theory-testing case study of the antiretroviral treatment adherence club, South Africa
Conclusion: A theory-based understanding provides valuable lessons towards the adaptive implementation of the adherence club intervention. (Source: Southern African Journal of HIV Medicine)
Source: Southern African Journal of HIV Medicine - June 25, 2019 Category: African Health Authors: Ferdinand C. Mukumbang Source Type: research

Vaginal practices among women at risk for HIV acquisition in Soweto, South Africa
Conclusion: Despite the high incidence of HIV in our setting, VP are still common and are associated with other behavioural risks for HIV. Further study is needed to assess whether clinician education may reduce VP and therefore should be included in HIV risk reduction counselling. (Source: Southern African Journal of HIV Medicine)
Source: Southern African Journal of HIV Medicine - June 19, 2019 Category: African Health Authors: Erica Lazarus Source Type: research

A cross-sectional study of the factors associated with male circumcision status among college youth in Ndola, Zambia, 2016
Conclusion: Students had adequate knowledge about the safety of medical circumcision, and the subsequent risk reduction of HIV infection. Interventions aimed at addressing negative sexual perceptions about circumcision may increase VMMC coverage among college students. (Source: Southern African Journal of HIV Medicine)
Source: Southern African Journal of HIV Medicine - June 19, 2019 Category: African Health Authors: Ernest Kateule Source Type: research

Peripartum HIV infection in very low birth weight infants fed ‘raw’ mother’s own milk
Conclusion: rMOM, in the presence of infant prophylaxis, was a safe feeding option for HIV-exposed VLBW infants. It should be strongly considered for these infants, as rMOM likely provides additional maternal and child benefits. (Source: Southern African Journal of HIV Medicine)
Source: Southern African Journal of HIV Medicine - June 18, 2019 Category: African Health Authors: Melantha Coetzee Source Type: research

Outcomes of patients enrolled in an antiretroviral adherence club with recent viral suppression after experiencing elevated viral loads
Conclusion: Our findings suggest that patients who struggled to achieve or maintain viral suppression in routine clinic care can have good retention and viral suppression outcomes in ACs, a differentiated ART delivery model, following suppression support. (Source: Southern African Journal of HIV Medicine)
Source: Southern African Journal of HIV Medicine - June 10, 2019 Category: African Health Authors: Joseph Sharp Source Type: research

Cognitive and behavioural determinants of multiple sexual partnerships and condom use in South Africa: Results of a national survey
Conclusion: Cognitive and behavioural factors were found to be predictors of risky sexual behaviours for HIV. This highlights the importance of considering personal perception and reasoning when attempting to understand and influence an individual’s sexual behaviour. This could be done through enhancing awa reness of HIV risk in the general population and by influencing cognitive behaviour change through community mobilisation, advocacy and creating activities to improve self-esteem. (Source: Southern African Journal of HIV Medicine)
Source: Southern African Journal of HIV Medicine - June 9, 2019 Category: African Health Authors: Patience G. Manjengwa Source Type: research

The role of rilpivirine in Southern Africa
Rilpivirine, a second-generation non-nucleoside reverse transcriptase inhibitor (NNRTI), is included as an option in first-line antiretroviral therapy (ART) for antiretroviral-na ïve individuals in treatment guidelines in high-income countries, including the United States and many European countries. Rilpivirine is available in a single-tablet fixed-dose combination, has a favourable tolerability profile and is of relatively low cost. However, rilpivirine has reduced effica cy in patients commencing ART at high viral loads. Therefore, baseline viral load testing is required before commencing rilpivirine, and it is not rec...
Source: Southern African Journal of HIV Medicine - May 28, 2019 Category: African Health Authors: Michelle A. Moorhouse Source Type: research

Tonsil histopathology in HIV-infected versus HIV-uninfected adults
Conclusion: The majority of patients undergoing tonsillectomy had benign conditions. HIV status does not appear to be a specific risk factor for tonsil malignancies, but advanced age may be. (Source: Southern African Journal of HIV Medicine)
Source: Southern African Journal of HIV Medicine - May 27, 2019 Category: African Health Authors: Ridwaan Essa Source Type: research

Occupational blood and body fluid exposures and human immunodeficiency virus post-exposure prophylaxis amongst intern doctors
Conclusion: Occupational blood and body fluid exposures are common amongst intern doctors. It is recommended that regular training, health education and monitoring compliance should be incorporated during the induction of medical intern doctors in hospitals. The availability of PEP regimens with better tolera bility will encourage compliance. (Source: Southern African Journal of HIV Medicine)
Source: Southern African Journal of HIV Medicine - May 21, 2019 Category: African Health Authors: Sunday J. Aigbodion Source Type: research

Sexual behaviours, awareness and perceptions towards voluntary medical male circumcision among students in Dr Kenneth Kaunda District, South Africa
Conclusion: The findings suggest that there is a high level of awareness on VMMC among college students in relation to its positive role towards reducing STIs and the enhancement of penile hygiene. (Source: Southern African Journal of HIV Medicine)
Source: Southern African Journal of HIV Medicine - May 21, 2019 Category: African Health Authors: Sam Mndzebele Source Type: research

Virologic and immunologic responses of patients on highly active antiretroviral therapy in a rural community health centre in Limpopo, South Africa: A retrospective study
Conclusions: Viral suppression in the study population was inferior to the UNAIDS target of 90%. The sustainability of viral suppression, once attained, was also low. These may have a negative impact on HIV transmission. (Source: Southern African Journal of HIV Medicine)
Source: Southern African Journal of HIV Medicine - May 21, 2019 Category: African Health Authors: Aniekan Edet Source Type: research

‘We must treat them like all the other people’: Evaluating the Integrated Key Populations Sensitivity Training Programme for Healthcare Workers in South Africa
Conclusion: The findings suggest that sensitisation training increases healthcare workers’ knowledge and awareness about specific HIV-related health needs and psychosocial vulnerabilities of key populations, reduces moralising and judgemental attitudes, and results in healthcare workers feeling more skilled to provide appropriate and sensitive services. (Source: Southern African Journal of HIV Medicine)
Source: Southern African Journal of HIV Medicine - April 29, 2019 Category: African Health Authors: Zoe Duby Source Type: research