Ocular manifestations of people living with HIV in Tunisia
Conclusion: Various ophthalmic manifestations were observed in PLWH. The most common lesion was retinopathy. Ocular involvement can be serious leading to poor visual prognosis, which requires close collaboration between the ophthalmologist and infectious disease physician. (Source: Southern African Journal of HIV Medicine)
Source: Southern African Journal of HIV Medicine - March 19, 2021 Category: African Health Authors: Dorsaf Saadouli Source Type: research

Immune activation and arterial stiffness in lean adults with HIV on antiretroviral therapy
Conclusion: Our population of lean PLWH had increased immune activation and higher cfAiX, a marker of arterial stiffness, compared to HIV-negative persons. The negative association between immune activation and arterial stiffness as measured by crPWV in PLHW on long-term treatment needs further elucidation. (Source: Southern African Journal of HIV Medicine)
Source: Southern African Journal of HIV Medicine - March 19, 2021 Category: African Health Authors: Longa Kaluba Source Type: research

Access to HIV services and viral load suppression among children during the 90-90-90 strategy implementation in South Africa: A time series analysis
Conclusion: Although the COJ has recorded progress in adult HIV testing, ART initiation and retention, children living with HIV aged 0 –15 years continue to experience less access to HIV services and lower VL suppression than youths and adults of ≥ 15 years. Therefore, to ensure that the 90-90-90 targets are achieved across different age groups, children must be prioritised so that they can equally access these services with ad ults. (Source: Southern African Journal of HIV Medicine)
Source: Southern African Journal of HIV Medicine - March 17, 2021 Category: African Health Authors: Juliet C.Y. Nyasulu Source Type: research

The clinical and demographic profile of women living with HIV admitted to the acute unit at Stikland Psychiatric Hospital
Conclusion: Our findings may inform service planning and emphasise the need for targeted intervention strategies to improve treatment outcomes in this vulnerable group. (Source: Southern African Journal of HIV Medicine)
Source: Southern African Journal of HIV Medicine - March 16, 2021 Category: African Health Authors: Jean-Marie le Roux Source Type: research

HIV-1/2 differentiation in a South African public laboratory
Conclusion: The multispot HIV-1/2 rapid assay demonstrated cross-reactivity between HIV-1 and HIV-2 antibodies. Human immunodeficiency virus -2 infections were not detected. (Source: Southern African Journal of HIV Medicine)
Source: Southern African Journal of HIV Medicine - March 12, 2021 Category: African Health Authors: Rendani T. Mafuyeka Source Type: research

Ten years of nurse-initiated antiretroviral treatment in South Africa: A narrative review of enablers and barriers
Conclusion: Identifying barriers and enablers will assist policymakers in implementing a structured programme for NIMART in South Africa and improve access, as well as the training and mentoring of professional nurses, which will enhance their competence and confidence. (Source: Southern African Journal of HIV Medicine)
Source: Southern African Journal of HIV Medicine - March 11, 2021 Category: African Health Authors: Talitha Crowley Source Type: research

World AIDS Day 2020: Reflections on global and South African progress and continuing challenges
Conclusion: While progress has been made in the past decade towards the global targets, much work remains to ensure that HIV transmission is curtailed and those that require treatment are initiated on treatment and are virally suppressed. (Source: Southern African Journal of HIV Medicine)
Source: Southern African Journal of HIV Medicine - March 10, 2021 Category: African Health Authors: Yogan Pillay Source Type: research

Nevirapine-induced Stevens-Johnson syndrome in children living with HIV in South Africa
Conclusions: This is the second largest case series of NVP-induced SJS in children to date and raises the possibility that the incidence of SJS in children may be higher than previously described. Further research is required to explore the risk factors associated with NVP-induced SJS in children. This case series highlights the negative impact of drug stock-outs on patient health outcomes. (Source: Southern African Journal of HIV Medicine)
Source: Southern African Journal of HIV Medicine - February 23, 2021 Category: African Health Authors: Jacques D. du Toit Source Type: research

Uptake of the Ithaka mobile application in Johannesburg, South Africa, for human immunodeficiency virus self-testing result reporting
Conclusion: Despite the small sample size, this study has shown that HIVST participants under pragmatic conditions were willing and able to self-report results via the app, whilst also identifying areas of improvement for scaling up. (Source: Southern African Journal of HIV Medicine)
Source: Southern African Journal of HIV Medicine - February 22, 2021 Category: African Health Authors: Alex E. Fischer Source Type: research

Profile of presentation of HIV-positive patients to an emergency department in Johannesburg, South Africa
Conclusion: Human immunodeficiency virus-positive patients presenting to the CMJAH ED demonstrated a high prevalence of opportunistic infections, required a prolonged hospital stay and had high mortality rates. There is a need to improve the quality of ART services and accessibility to care. (Source: Southern African Journal of HIV Medicine)
Source: Southern African Journal of HIV Medicine - January 29, 2021 Category: African Health Authors: Abdullah E. Laher Source Type: research

False-positive rapid diagnostic tests in paediatric and obstetric patients in South Africa
Conclusion: With high numbers tested and a low yield of new cases, each individual case of discordancy may cause unnecessary distress, confusion and treatment, particularly in high-risk scenarios like pregnancy. Trends of false-positive and discordant RDT results should be monitored and inform HTS guidelines. (Source: Southern African Journal of HIV Medicine)
Source: Southern African Journal of HIV Medicine - January 29, 2021 Category: African Health Authors: Josephine Keal Source Type: research

A trio of infectious diseases and pulmonary embolism: A developing world ’s reality
Conclusion: This scenario is relevant in low to middle-income countries. The utilisation of a raised D-Dimer in the setting of all four coexisting conditions in arriving at a definite diagnosis remains uncertain. We noted that despite our index patient being on thrombo-prophylaxis, she developed PE highlighting the need for increased vigilance in all COVID-19 patients, even those on prophylactic anticoagulation. (Source: Southern African Journal of HIV Medicine)
Source: Southern African Journal of HIV Medicine - January 28, 2021 Category: African Health Authors: Somasundram Pillay Source Type: research

Estimating qualification and factors associated with third line ART referral in the Western Cape
Conclusion:This study adds to a limited body of knowledge regarding third-line ART programmes. The findings indicate missed opportunities for and inappropriate referral of patients. Factors associated with referral were largely health system related. Clinician awareness and compliance with referral remain unknown and may be contributory. (Source: Southern African Journal of HIV Medicine)
Source: Southern African Journal of HIV Medicine - January 28, 2021 Category: African Health Authors: Sadiyya Sheik Source Type: research

Skin and mucosal manifestations of an AIDS-related systemic mycosis
No abstract available. (Source: Southern African Journal of HIV Medicine)
Source: Southern African Journal of HIV Medicine - January 28, 2021 Category: African Health Authors: Michael T. Boswell Source Type: research

Administering human immunodeficiency virus post-exposure prophylaxis: challenges experienced by mothers in Lusaka, Zambia
Conclusion: Post-exposure prophylaxis as part of the PMTCT programme is key to eliminating mother-to-child transmission of HIV. Postnatal support for women administering PEP to their children can be enhanced through counselling that is person- and family-centred is culturally sensitive and offers differentiated services that include PEP, integrated mother-and-child healthcare and access to support groups. (Source: Southern African Journal of HIV Medicine)
Source: Southern African Journal of HIV Medicine - January 27, 2021 Category: African Health Authors: Mildred Lusaka Source Type: research