Delays in third-line antiretroviral therapy and outcomes in North West province
Conclusion: This study showed a prolonged waiting period for TLART initiation mainly between detected high viral load to requesting of resistance tests; many factors could have contributed, including clinicians’ delayed responses to elevated viral loads. Mortality was high before TLART could be initiated. T he process of TLART initiation needs to be made more efficient. Healthcare services should be strengthened to (1) recognise and manage virological failure early and identify those eligible for resistance testing, (2) ensure access to resistance testing and appropriately skilled clinicians, and (3) s treamline approva...
Source: Southern African Journal of HIV Medicine - October 24, 2022 Category: African Health Authors: Babalwa Majova Source Type: research

Low-level viraemia despite emergence of dolutegravir-resistant variants
No abstract available. (Source: Southern African Journal of HIV Medicine)
Source: Southern African Journal of HIV Medicine - September 30, 2022 Category: African Health Authors: Johannes C. Botha Source Type: research

Southern African HIV Clinicians Society 2022 guideline for the management of sexually transmitted infections: Moving towards best practice
No abstract available. (Source: Southern African Journal of HIV Medicine)
Source: Southern African Journal of HIV Medicine - September 27, 2022 Category: African Health Authors: Remco P.H. Peters Source Type: research

Rifampicin resistance and mortality in patients hospitalised with HIV-associated tuberculosis
Conclusion: Mortality at 12 weeks in participants with RR-TB was high compared to participants with RS-TB. Delays in the initiation of appropriate treatment and poorer regimen efficacy are proposed as contributors to higher mortality in hospitalised patients with HIV and RR-TB. (Source: Southern African Journal of HIV Medicine)
Source: Southern African Journal of HIV Medicine - September 27, 2022 Category: African Health Authors: Ruan Spies Source Type: research

The sexual and reproductive health needs of young people living with HIV in Gauteng, South Africa
Conclusion: Multiple SRH needs were identified. Interventions are needed to improve parental guidance on SRH issues, increase contraception knowledge and access, and provide better male-centred care. (Source: Southern African Journal of HIV Medicine)
Source: Southern African Journal of HIV Medicine - September 6, 2022 Category: African Health Authors: Bandile E. Ndlazi Source Type: research

Ethically acceptable consent approaches to adolescent research in South Africa
Conclusion: The inclusion of adolescents in research is critical in informing appropriate and effective health services for this vulnerable population, whilst providing an opportunity to link them into care and services where relevant. (Source: Southern African Journal of HIV Medicine)
Source: Southern African Journal of HIV Medicine - September 5, 2022 Category: African Health Authors: Marian Loveday Source Type: research

Dolutegravir for second-line treatment: Programmatic implications of new evidence
No abstract available. (Source: Southern African Journal of HIV Medicine)
Source: Southern African Journal of HIV Medicine - September 5, 2022 Category: African Health Authors: Ying Zhao Source Type: research

COVID-19 vaccine acceptance and associated factors among people living with HIV in the Middle East and North Africa region
Conclusion: Findings of the study can help researchers, health officials, and other health system actors understand the predictors and barriers to COVID-19 vaccine acceptance reported by PLHIV. This understanding could inform the future planning of interventions tailored to PLHIV. (Source: Southern African Journal of HIV Medicine)
Source: Southern African Journal of HIV Medicine - August 24, 2022 Category: African Health Authors: Rahma Mohamed Source Type: research

Cutaneous squamous cell carcinoma in vertically acquired HIV and epidermodysplasia verruciformis
Conclusion: Patients with acquired EV require thorough, frequent examination for skin lesions with possible malignant transformation. Early identification of malignant transformation and treatment with surgical intervention is curative. (Source: Southern African Journal of HIV Medicine)
Source: Southern African Journal of HIV Medicine - June 27, 2022 Category: African Health Authors: Linda A. Mandikiyana Chirimuta Source Type: research

Rechallenge after anti-tuberculosis drug-induced liver injury in a high HIV prevalence cohort
Conclusion: Rechallenge was successful in most of our cohort. Pyrazinamide rechallenge should be carefully considered. (Source: Southern African Journal of HIV Medicine)
Source: Southern African Journal of HIV Medicine - June 14, 2022 Category: African Health Authors: Muhammed Shiraz Moosa Source Type: research

Digitally supported HIV self-testing increases facility-based HIV testing capacity in Ekurhuleni, South Africa
Conclusion: Digitally supported HIVST increased the number of clients completing HIV testing in the health facility, without a need to significantly increase staff or space. Facility-based digitally assisted HIVST has the potential to increase HIV testing in high HIV prevalence clinic populations. (Source: Southern African Journal of HIV Medicine)
Source: Southern African Journal of HIV Medicine - June 13, 2022 Category: African Health Authors: Nolundi T. Mshweshwe-Pakela Source Type: research

Factors associated with viral suppression among adolescents on antiretroviral therapy in Free State province, South Africa
Conclusion: Tailored interventions should be developed to improve viral suppression among adolescents on ART. (Source: Southern African Journal of HIV Medicine)
Source: Southern African Journal of HIV Medicine - June 13, 2022 Category: African Health Authors: Balsam A.Y. Elashi Source Type: research

Splenic hydatid disease in pregnancy
Conclusion: Our aim is to highlight the unique treatment challenges of hydatid disease in pregnancy and the need for a multidisciplinary team approach when managing complex cases of hydatid disease. (Source: Southern African Journal of HIV Medicine)
Source: Southern African Journal of HIV Medicine - May 26, 2022 Category: African Health Authors: Kirstie F. Thomson Source Type: research

Corrigendum: The influence of HIV infection and antiretroviral treatment on pulmonary function in individuals in an urban setting in sub-Saharan Africa
No abstract available. (Source: Southern African Journal of HIV Medicine)
Source: Southern African Journal of HIV Medicine - May 20, 2022 Category: African Health Authors: Oda E. van den Berg Source Type: research

Tracking adverse drug reactions and medication errors in the Central Chronic Medicine Dispensing and Distribution (CCMDD) programme in South Africa
Conclusion: About one in seven patients reported ADRs under TLD. Medication errors were low, possibly due to effective quality control measures and stable patients being on the programme. Knowing the frequency of ADRs and medication errors is critical for enhancing the CCMDD programme. (Source: Southern African Journal of HIV Medicine)
Source: Southern African Journal of HIV Medicine - May 19, 2022 Category: African Health Authors: Kennedy Otwombe Source Type: research