Southern African Journal of HIV Medicine This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

B-cell and T-cell activation in South African HIV-1-positive non-Hodgkin ’s lymphoma patients
Conclusion: B-cell activation is increased in HIV-positive NHL patients and is associated with reduced regulatory T-cell populations and increased CD8+ T-cell activation. (Source: Southern African Journal of HIV Medicine)
Source: Southern African Journal of HIV Medicine - November 7, 2018 Category: African Health Authors: Brian T. Flepisi Source Type: research

Appropriate clinical use of darunavir 800 mg
Not applicable. (Source: Southern African Journal of HIV Medicine)
Source: Southern African Journal of HIV Medicine - October 18, 2018 Category: African Health Authors: Michelle A. Moorhouse Source Type: research

Guidelines to support HIV-affected individuals and couples to achieve pregnancy safely: Update 2018
Not applicable. (Source: Southern African Journal of HIV Medicine)
Source: Southern African Journal of HIV Medicine - October 18, 2018 Category: African Health Authors: Natasha E.C.G. Davies Source Type: research

Southern African HIV Clinicians Society Guidance on the use of dolutegravir in first-line antiretroviral therapy
Not applicable.   (Source: Southern African Journal of HIV Medicine)
Source: Southern African Journal of HIV Medicine - October 17, 2018 Category: African Health Authors: Michelle A. Moorhouse Source Type: research

Will the current National Strategic Plan enable South Africa to end AIDS, Tuberculosis and Sexually Transmitted Infections by 2022?
Conclusion: To realistically achieve the NSP targets and goals, a robust, client-centred strategy addressing the NSP gaps needs to be implemented. The strategy must be cost-effective; provide active linkage to care; and address health system weaknesses that inhibit its successful implementation, including hum an resources, service delivery and supply chain management, accountability and monitoring and evaluation (M&E).  (Source: Southern African Journal of HIV Medicine)
Source: Southern African Journal of HIV Medicine - October 4, 2018 Category: African Health Authors: Kathryn L. Hopkins Source Type: research

The metabolic syndrome and renal function in an African cohort infected with human immunodeficiency virus
Conclusion: The HIV-infected Africans with MetS had almost twofold higher uACR, despite the low prevalence of MetS, compared to their uninfected counterparts. The combination of HIV and MetS seemed to increase the risk for renal impairment. (Source: Southern African Journal of HIV Medicine)
Source: Southern African Journal of HIV Medicine - September 20, 2018 Category: African Health Authors: Edith Phalane Source Type: research

Barriers to HIV service utilisation by people living with HIV in two provinces of Zimbabwe: Results from 2016 baseline assessment
Conclusion: Our assessment has indicated that there are several barriers to the utilisation of HIV services by PLHIV in the two provinces of Zimbabwe. As new strategies and programmes are being introduced in the current resource-constrained era, efforts should be made to understand the needs of the clients. I f programmes are designed with an effort to address some of these challenges, there is a possibility that countries will quickly achieve the 90-90-90 targets set by The Joint United Nations Programme on HIV/AIDS. (Source: Southern African Journal of HIV Medicine)
Source: Southern African Journal of HIV Medicine - August 9, 2018 Category: African Health Authors: Taurayi A. Tafuma Source Type: research

Development of a clinical prediction rule to diagnose Pneumocystis jirovecii pneumonia in the World Health Organization ’s algorithm for seriously ill HIV-infected patients
Conclusion: We developed simple clinical prediction rules for PJP, which, if externally validated, could assist decision-making in the WHO seriously ill algorithm. (Source: Southern African Journal of HIV Medicine)
Source: Southern African Journal of HIV Medicine - July 23, 2018 Category: African Health Authors: Gary Maartens Source Type: research

An overview of tenofovir and renal disease for the HIV-treating clinician
Tenofovir disoproxil fumarate (TDF, commonly termed ‘tenofovir’) is the antiretroviral most commonly implicated in antiretroviral-induced nephrotoxicity. As patients on successful antiretroviral therapy (ART) age, their risk for developing renal disease may increase in part because of ART itself, but more importantly, because of HIV-associated an d non-HIV-associated comorbidity. Therefore, clinicians need an approach to managing renal disease in people on TDF. TDF as a cause of acute kidney injury (AKI) or chronic kidney disease (CKD) is uncommon, and clinicians should actively exclude other causes (Box 1). In TDF-ass...
Source: Southern African Journal of HIV Medicine - July 17, 2018 Category: African Health Authors: Willem D.F. Venter Source Type: research

Implementing emergency department-based HIV testing in a low-resource setting: The value of a structured feasibility assessment tool
Conclusions: Although control of the HIV epidemic requires innovative testing strategies and treatment, specific assessments are warranted on how to incorporate routine HIV testing into an acute care facility like the ED, which typically has many competing priorities. The use of a prospective structured tool i ncorporating both barriers and benefits can provide valuable field-tested guidance for increased programme planning for HIV testing. (Source: Southern African Journal of HIV Medicine)
Source: Southern African Journal of HIV Medicine - July 16, 2018 Category: African Health Authors: Madeleine Whalen Source Type: research

HIV retesting in pregnant women in South Africa: Outcomes of a quality improvement project targeting health systems ’ weaknesses
Conclusion: Service coverage and overall impact of HIV programmes can be raised through care-process analysis that optimises patient flow, supported by targeted QI interventions. These QI methodologies may be effective elsewhere for identifying new HIV infections in pregnant/breastfeeding women, and possibly in other services. (Source: Southern African Journal of HIV Medicine)
Source: Southern African Journal of HIV Medicine - July 12, 2018 Category: African Health Authors: Lauren M. Golden Source Type: research

Hypertriglyceridaemia and the risk of pancreatitis six months post lopinavir/ritonavir initiation
Conclusion: Triglyceride levels were not substantially elevated to induce pancreatitis at six months post initiation of LPV/r, but were elevated above the accepted upper normal limit of 1.70 mmol/L which may have implications for cardiovascular risk. (Source: Southern African Journal of HIV Medicine)
Source: Southern African Journal of HIV Medicine - June 26, 2018 Category: African Health Authors: Wilhelm P. Greffrath Source Type: research

Suicidal overdose of dolutegravir: A case report
We report a 29-year-old man with clinical stage 1 HIV infection who had been started on DTG, tenofovir and emtricitabine eight months prior, and who was admitted following a suicidal overdose of 1500 mg o f DTG. He reported only minor symptoms including vomiting, epigastric pain and dizziness; which promptly resolved following supportive treatment. On admission, full blood count, liver function tests and electrocardiography were unremarkable. However, there was a non-progressive increase in serum cre atinine. After a month off ARVs, he was successfully restarted on antiretroviral therapy without any serious adverse effect....
Source: Southern African Journal of HIV Medicine - June 18, 2018 Category: African Health Authors: Rahul Daimari Source Type: research

HIV care and treatment clinic performance following President ’s Emergency Plan for AIDS Relief-funded infrastructure improvement in Tanzania
Conclusion: Patient retention in care improved in HIV care and treatment facilities with infrastructure improvements. However, the overall number of patients newly enrolled and initiated on ART declined and attrition increased in facilities after improvements. (Source: Southern African Journal of HIV Medicine)
Source: Southern African Journal of HIV Medicine - June 14, 2018 Category: African Health Authors: Boniphace M. Idindili Source Type: research

Guidelines for the vaccination of HIV-infected adolescents and adults in South Africa
No abstract available. (Source: Southern African Journal of HIV Medicine)
Source: Southern African Journal of HIV Medicine - May 23, 2018 Category: African Health Authors: Sipho K. Dlamini Source Type: research