Knowledge about male circumcision and perception of risk for HIV among youth in Harare, Zimbabwe
Conclusion: The study provides two recommendations: the need to strengthen perceived susceptibility to HIV among the youth and the need for advocacy on the health benefits of male circumcision. (Source: Southern African Journal of HIV Medicine)
Source: Southern African Journal of HIV Medicine - April 29, 2019 Category: African Health Authors: Kudzaishe Mangombe Source Type: research

Correlation of hair and plasma efavirenz concentrations in HIV-positive South Africans
Conclusion: The results from this study provide further insight into the potential of using hair as a matrix for measuring antiretroviral concentrations. However, challenges experienced in collecting hair samples suggest that this adherence measure may have limited utility in an African population. (Source: Southern African Journal of HIV Medicine)
Source: Southern African Journal of HIV Medicine - April 28, 2019 Category: African Health Authors: Jenna Johnston Source Type: research

Comparison of non-invasive methods of assessing liver fibrosis in combination ART-experienced Zimbabweans
Conclusion: Our data demonstrate a high prevalence of asymptomatic liver fibrosis among combination ART-experienced individuals in Zimbabwe, and this warrants adequate monitoring of liver fibrosis in individuals on ART. Discordance of fibrosis results among the algorithms and individual biomarkers and calls f or further work in identifying optimal biomarkers for detection of asymptomatic fibrosis.Keywords: Liver fibrosis; Non-invasive methods; Biomarkers; Combination anti-retroviral therapy; Zimbabwe. (Source: Southern African Journal of HIV Medicine)
Source: Southern African Journal of HIV Medicine - April 10, 2019 Category: African Health Authors: Brenda Nherera Source Type: research

HIV viraemia during pregnancy in women receiving preconception antiretroviral therapy in KwaDukuza, KwaZulu-Natal
Conclusions: Approximately 20% of women receiving PCART may demonstrate viraemia. Half of these may be transient. Poor adherence is associated with viraemia, and efforts to encourage and monitor adherence are essential. The rate of unplanned pregnancies is high, and antiretroviral therapy programmes should foc us on family planning needs of women in the reproductive age group to prevent viral non-suppression prior to pregnancy.Keywords: Preconception Antiretroviral Therapy; HIV; Viraemia; Antenatal Care; Adherence. (Source: Southern African Journal of HIV Medicine)
Source: Southern African Journal of HIV Medicine - April 9, 2019 Category: African Health Authors: Vuyokazi Ntlantsana Source Type: research

HIV-associated cavernous sinus disease
Conclusion: In HIV-infected patients, histological confirmation of cavernous sinus pathology is not readily available for various reasons. In resource-limited settings, one should first actively search for extracranial evidence of tuberculosis, lymphoma, syphilis and primary malignancy and manage appropriatel y. Only if such evidence is lacking should a referral for biopsy be considered. (Source: Southern African Journal of HIV Medicine)
Source: Southern African Journal of HIV Medicine - March 19, 2019 Category: African Health Authors: Cait-lynn D. Wells Source Type: research

Cutaneous tuberculosis in HIV-infected individuals: Lessons learnt from a case series
Introduction: Extrapulmonary tuberculosis (TB) causes a significant burden of disease worldwide, especially among HIV-infected individuals and those with other immunosuppressive conditions. Cutaneous TB is an important manifestation of extrapulmonary TB but is uncommonly reported in South Africa despite the hig h burden of HIV and TB co-infection. There is a paucity of published data on clinical presentation and outcome of cutaneous TB in this context. Raising awareness of this condition among clinicians is imperative to improve early diagnosis and optimise treatment outcomes.Patient presentation: In this series, we pres...
Source: Southern African Journal of HIV Medicine - March 11, 2019 Category: African Health Authors: Vhudzani Tshisevhe Source Type: research

Targeted mentoring for human immunodeficiency virus programme support in South Africa
Conclusion: These findings suggest that the success of mentoring programmes in LMICs may require specific attention to both knowledge transfer and the management of interpersonal relationships. (Source: Southern African Journal of HIV Medicine)
Source: Southern African Journal of HIV Medicine - February 14, 2019 Category: African Health Authors: Geoffrey Jobson Source Type: research

HIV status and mortality of surgical inpatients in rural Zimbabwe: A retrospective chart review
Background: People living with HIV treated with antiretroviral therapy (ART) are now living longer and thus many are requiring surgical procedures. For healthcare resource planning, it would be helpful to better understand the prevalence of HIV in surgical patients, the types of surgery HIV-positive patients are undergoing and whether HIV status impacts mortality.Objective: The goal of this study was to determine the prevalence of HIV in surgical inpatients and the extent of ART coverage, as well as to assess any differences between HIV-positive and HIV-negative patients in type of surgery undergone and in-hospital morta...
Source: Southern African Journal of HIV Medicine - January 24, 2019 Category: African Health Authors: Pascal Migaud Source Type: research

Sexually transmitted infections, the silent partner in HIV-infected women in Zimbabwe
Conclusion: A high prevalence of predominantly asymptomatic STIs is reported in a cohort of HIV-infected women. Syndromic management results in underdiagnosis of asymptomatic patients. More than three lifetime sexual partners and less formal education are risk factors for coinfection with non-viral STI. High- risk women should be screened using aetiological methods. (Source: Southern African Journal of HIV Medicine)
Source: Southern African Journal of HIV Medicine - January 23, 2019 Category: African Health Authors: Sara Lowe Source Type: research

Table of Contents Vol 19, No 1 (2018)
(Source: Southern African Journal of HIV Medicine)
Source: Southern African Journal of HIV Medicine - December 13, 2018 Category: African Health Authors: Editorial Office Source Type: research

Acknowledgement to reviewers
(Source: Southern African Journal of HIV Medicine)
Source: Southern African Journal of HIV Medicine - December 5, 2018 Category: African Health Authors: Editorial Office Source Type: research

A case of a drug reaction to sulfasalazine in a patient infected with HIV
Conclusion: In conclusion, it is important to consider drug reactions when evaluating patients infected with HIV. (Source: Southern African Journal of HIV Medicine)
Source: Southern African Journal of HIV Medicine - December 3, 2018 Category: African Health Authors: Leanne Swart Source Type: research

Human immunodeficiency virus infection and older adults: A retrospective single-site cohort study from Johannesburg, South Africa
Conclusion: HIV-infected South African adults aged over 50 years differ in characteristics and outcomes compared to their younger counterparts and justify specialised management within HIV treatment facilities. (Source: Southern African Journal of HIV Medicine)
Source: Southern African Journal of HIV Medicine - November 29, 2018 Category: African Health Authors: India Butler Source Type: research

Sexual reproductive healthcare utilisation and HIV testing in an integrated adolescent youth centre clinic in Cape Town, South Africa
Conclusion: Youth were significantly more likely to access SRH services at DTHF-YC compared with the PC. The differences were greatest in contraception use by female adolescents< 18 years and HCT by male youth. Increased HCT did not increase youth HIV case detection. Data from DTHF-YC suggest that youth-friendly healthcare providers integrated into community youth spaces may increase youth HCT and contraception rates. (Source: Southern African Journal of HIV Medicine)
Source: Southern African Journal of HIV Medicine - November 26, 2018 Category: African Health Authors: Andrea S. Mendelsohn Source Type: research

Prevalence and outcomes of central venous catheter-related bacteraemia in HIV-infected versus non-HIV-infected patients undergoing haemodialysis treatment for end-stage kidney disease
Conclusion: The infection rate in CVC HD is not more frequent in HIV-infected patients, provided that CD4+ count is ≥ 200 cells/µL and the patient is virologically suppressed. Outcomes following intravenous antibiotic and removal of the CVC are similar in HIV-infected and non-infected patients but response to treatment is slower in HIV-infected patients. A high index of suspicion is needed in detecting CVC-related bacteraemia. (Source: Southern African Journal of HIV Medicine)
Source: Southern African Journal of HIV Medicine - November 22, 2018 Category: African Health Authors: Nuria Avila-Danguillecourt Source Type: research