Ultrathin Bronchoscopy for the Diagnosis of Peripheral Pulmonary Lesions: A Meta-Analysis
Conclusions: Ultrathin bronchoscopy is an excellent tool for peripheral pulmonary lesion diagnosis with a low complication rate. The diagnostic yield of ultrathin bronchoscopy was significantly higher with larger channel size, which might be attributed to the availability of radial endobronchial ultrasound.Respiration (Source: Respiration)
Source: Respiration - November 22, 2022 Category: Respiratory Medicine Source Type: research

Medical Thoracoscopy and Intrapleural Fibrinolytic Therapy for the Management of Pleural Empyema: A Cohort Study
Conclusions: Patients with pleural empyema treated in earlier stages (free-flowing or multiloculated effusion) with medical thoracoscopy show significantly better results than patients treated in later stages (organized empyema). This approach is safe, minimally invasive, and efficient in these patients with disease having relevant mortality; however, patient selection remains essential.Respiration (Source: Respiration)
Source: Respiration - November 17, 2022 Category: Respiratory Medicine Source Type: research

Audit of Asthma Exacerbation Management in a Swiss General Hospital
Conclusion: To increase the guideline conformity and quality of asthma exacerbation management, the severity should be better assessed, especially by routinely performing PEF measurements. Treatment needs to be intensified; in particular, the ICS dose should be increased significantly and systemic glucocorticosteroids should be given with a lower threshold.Respiration (Source: Respiration)
Source: Respiration - November 14, 2022 Category: Respiratory Medicine Source Type: research

A Novel Mask with Selective Ports for Inflow and Outflow Reduces CO < sub > 2 < /sub > Rebreathing during Non-Invasive Ventilation: A Physiological Study in Healthy Volunteers
Conclusion: The new mask design with two ports for inhaled and exhaled gases reduced the amount of CO2 rebreathing in all tested ventilation settings. The CO2 rebreathing reduction did not decrease minute ventilation in healthy volunteers.Respiration (Source: Respiration)
Source: Respiration - November 10, 2022 Category: Respiratory Medicine Source Type: research

Observational, Multicenter Study on the Efficacy, Tolerability, and Safety of Nintedanib in Patients with Idiopathic Pulmonary Fibrosis Older than 80 Years
Conclusions: Nintedanib is effective and safe in patients with IPF aged #x3e;80 years, and no significant differences were found when clinical outcomes were compared with those of younger patients. Thus, older age should not be a barrier for the early prescription of antifibrotic treatment in IPF patients.Respiration (Source: Respiration)
Source: Respiration - November 10, 2022 Category: Respiratory Medicine Source Type: research

Effect of Respiratory Events on Health-Related Quality of Life in Patients Treated with Long-Term Noninvasive Ventilation
Conclusion: In a group of patients with long-term NIV, undesired respiratory events during NIV are associated with lower HRQoL in several of the SRI subscales. We suggest designing interventional studies to confirm the possible relationship between HRQoL and respiratory events during long-term NIV.Respiration (Source: Respiration)
Source: Respiration - November 9, 2022 Category: Respiratory Medicine Source Type: research

Comparison of Lung, Lobe, and Airway Volumes between Supine and Upright Computed Tomography and Their Correlation with Pulmonary Function Test in Patients with Chronic Obstructive Pulmonary Disease
Conclusions: Upright CT-based volumes were more correlated with PFT measurements than supine CT-based volumes in patients with COPD. Unlike other lobes and airway, inspiratory/expiratory right middle lobe volumes were significantly lower in the standing than supine position.Respiration (Source: Respiration)
Source: Respiration - November 9, 2022 Category: Respiratory Medicine Source Type: research

Meta-Analysis on Utility of Bronchoscopy in Addition to Computed Tomography Thorax in the Investigation of Lung Cancer in Patients with Haemoptysis
Conclusion: CT scan showed a higher diagnostic accuracy than bronchoscopy. This study indicated that bronchoscopy offers an insignificant additional value in the investigation of lung cancer in patients with haemoptysis and a negative CT scan.Respiration (Source: Respiration)
Source: Respiration - November 9, 2022 Category: Respiratory Medicine Source Type: research

Nature and Trends in Personal Payments Made to the Respiratory Physicians by Pharmaceutical Companies in Japan between 2016 and 2019
Conclusion: The majority of respiratory specialists had increasingly received more personal payments from pharmaceutical companies for the reimbursement of lecturing, consulting, and writing between 2016 and 2019. These increasing financial relationships with pharmaceutical companies might cause conflicts of interest among respiratory physicians.Respiration (Source: Respiration)
Source: Respiration - November 9, 2022 Category: Respiratory Medicine Source Type: research

Risk Factors of Rapid FEV < sub > 1 < /sub > Decline in a Real-World Chronic Obstructive Pulmonary Disease Cohort
Conclusions: We identified the independent risk factors for rapid FEV1 decline. This information may assist physicians in the early detection and pertinent management of rapid decline among patients with COPD.Respiration (Source: Respiration)
Source: Respiration - November 4, 2022 Category: Respiratory Medicine Source Type: research

A Diagnostic Predictive Model of Bronchoscopy with Radial Endobronchial Ultrasound for Peripheral Pulmonary Lesions
Conclusions: The predictive model using the seven factors revealed a good performance in estimating the diagnostic yield.Respiration (Source: Respiration)
Source: Respiration - November 3, 2022 Category: Respiratory Medicine Source Type: research

Analysis of Patients with Asthma and Mixed Granulocytic Inflammatory Pattern in Sputum
Conclusion: Aging and presence of comorbidities, in particular obesity and hypertension, are characteristics of patients with asthma and mixed granulocytic pattern. They could respond less well to treatment than eosinophilic patients.Respiration (Source: Respiration)
Source: Respiration - November 3, 2022 Category: Respiratory Medicine Source Type: research

What Is Interventional Pulmonology? A Proposal for Standardization
Respiration (Source: Respiration)
Source: Respiration - November 1, 2022 Category: Respiratory Medicine Source Type: research

Impairment of Inspiratory Muscle Function after COVID-19
Conclusions: This study shows that in long-COVID patients, respiratory symptoms may be mainly caused by reduced inspiratory muscle strength. Assessment of PImax and P0.1 might better explain dyspnea than classical lung function tests and DLCO. A prospective study is needed to confirm these results.Respiration (Source: Respiration)
Source: Respiration - October 28, 2022 Category: Respiratory Medicine Source Type: research

Costs of Pharmacological and Non-Pharmacological Interventions in Interstitial Lung Disease Management in Germany
Conclusion: Stabilizing lung function and reducing the impact of PH and GERD are crucial in reducing the economic burden of ILD. There is an urgent need for effective treatment options, especially in CTD-ILD.Respiration (Source: Respiration)
Source: Respiration - October 27, 2022 Category: Respiratory Medicine Source Type: research