Effect of Triple Combination CFTR Modulator Therapy on Sleep in Adult Patients with Cystic Fibrosis
Conclusions: Initiation of ELX/TEZ/IVA resulted in significant improvements in SDB in adult pwCF.Respiration (Source: Respiration)
Source: Respiration - May 20, 2022 Category: Respiratory Medicine Source Type: research

Is It Possible to Predict Respiratory Evolution in COVID-19 Patients?
Respiration (Source: Respiration)
Source: Respiration - May 17, 2022 Category: Respiratory Medicine Source Type: research

Primary Mediastinal Large B-Cell Lymphoma Achieved by Non-Cautery Assisted Transbronchial Mediastinal Cryobiopsy
Transbronchial mediastinal cryobiopsy is a novel sampling strategy that shows improved diagnostic utility for mediastinal lesions, particularly in rare tumors and benign disorders, as compared to standard endobronchial ultrasound-guided transbronchial needle aspiration. During this procedure, electrocautery incision is frequently needed to advance the cryoprobe through the airway into the mediastinal lesion, which however results in increased operative difficulty and prolonged procedural time. Here we present a case of mediastinal large B-cell lymphoma successfully diagnosed by transbronchial mediastinal cryobiopsy without...
Source: Respiration - May 16, 2022 Category: Respiratory Medicine Source Type: research

Deep Learning for Automatic Upper Airway Obstruction Detection by Analysis of Flow-Volume Curve
Conclusions: Deep learning could detect upper airway obstruction patterns from other classic patterns of ventilatory defects with high accuracy, whereas clinicians presented marked errors and variabilities. The model may serve as a support tool to enhance clinicians ’ correct diagnosis of upper airway obstruction using spirometry.Respiration (Source: Respiration)
Source: Respiration - May 12, 2022 Category: Respiratory Medicine Source Type: research

Congenital Chylothorax of the Newborn
Respiration (Source: Respiration)
Source: Respiration - May 12, 2022 Category: Respiratory Medicine Source Type: research

Predictors of Low and High Exhaled Nitric Oxide Values in Asthma: A Real-World Study
Conclusions: Stratifying patients by FENO level can identify specific asthma phenotypes with distinct clinical features and predictors useful in clinical practice to tailor treatment and improve asthmatic patients ’ outcomes.Respiration (Source: Respiration)
Source: Respiration - May 5, 2022 Category: Respiratory Medicine Source Type: research

Exercise Physiology at “Conversational Level” Is Not Impaired in Healthy Young Subjects Wearing Masks or Respirators
Conclusions: The present study findings suggested that inspiratory muscle strength and physiological parameters during “conversational level” exercise were not impaired under wearing masks in healthy, nonsmoking young adults.Respiration (Source: Respiration)
Source: Respiration - May 5, 2022 Category: Respiratory Medicine Source Type: research

Mathematical Arterialization of Capillary Blood for Blood Gas Analysis in Critically Ill Patients
Conclusion: In summary, v-TAC can be used for mathematical arterialization of capillary blood samples for blood gas analysis resulting in increased diagnostic accuracy for pO2.Respiration (Source: Respiration)
Source: Respiration - May 3, 2022 Category: Respiratory Medicine Source Type: research

Bifurcated Silicone Stents for the Management of Anastomotic Complications in Lung Transplanted Patients: Ten Years ’ Experience
Conclusions: The actual surgical anastomotic technique in LT provides new endoscopic challenges. CBS seem ideally positioned to address these difficulties safely and effectively but are associated with stent related complications requiring further endoscopic management.Respiration (Source: Respiration)
Source: Respiration - April 29, 2022 Category: Respiratory Medicine Source Type: research

Accuracy and Predictors of Success of EUS-B-FNA in the Diagnosis of Pulmonary Malignant Lesions: A Prospective Multicenter Italian Study
Conclusion: EUS-B-FNA is a safe and accurate method for the diagnosis of paraesophageal pulmonary lesions. The presence of ROSE is relevant for a complete molecular profiling in this selected cohort of patients with advanced lung cancer.Respiration (Source: Respiration)
Source: Respiration - April 28, 2022 Category: Respiratory Medicine Source Type: research

Anxiety, Depression and Quality of Life in Pulmonary Hypertension: A Comparison of Incident and Prevalent Cases
Conclusion: Physical domains of HRQoL seem to be more limited in incident patients with PH. Anxiety and depression are frequent in both groups. A screening for anxiety and depression is important from the onset of the diagnosis, and patients should receive appropriate therapy to improve HRQoL, anxiety and depression.Respiration (Source: Respiration)
Source: Respiration - April 27, 2022 Category: Respiratory Medicine Source Type: research

Future Perspectives of Revaluating Mild COPD
In 2020, COPD was the third leading cause of death worldwide. Lung function is central for the diagnosis of this disease, and COPD severity is still partially classified based on airflow obstruction, which can range from “mild” (GOLD 1 group, FEV1≥80% predicted) to “very severe” (GOLD 4, FEV1 #x3c;30% predicted). However, the term “mild COPD” needs to be carefully analyzed. Several studies have shown that even in the presence of a mild obstruction, patients can have significant symptoms, physiological deterioration, evidence of emphysema, and suffer from recurrent exacerbations. Small airways pathology signif...
Source: Respiration - April 25, 2022 Category: Respiratory Medicine Source Type: research

The Effect of Borderline Pulmonary Hypertension on Survival in Chronic Lung Disease
Conclusions: In ILD, any level of PH portends worse survival, while in COPD, only SPH presents a worse outcome.Respiration (Source: Respiration)
Source: Respiration - April 22, 2022 Category: Respiratory Medicine Source Type: research

Safety of Bronchoscopy after Acute Coronary Syndrome
Conclusion: Our study reinforces the safety of bronchoscopy after ACS. When clinically indicated with potential benefits outweighing risks, ACS should not contraindicate bronchoscopy.Respiration (Source: Respiration)
Source: Respiration - April 22, 2022 Category: Respiratory Medicine Source Type: research

Bronchoscopic Lung Volume Reduction Coil Treatment for Severe Emphysema: A Systematic Review and Meta-Analysis of Individual Participant Data
Conclusions: LVR-coil treatment in emphysema patients results in sustained improvements in pulmonary function and quality of life and shorter lived improvements in exercise capacity. Since the owner of this LVR-coil has decided to stop the production and newer generations LVR-coils are currently being developed, these results can act as a reference for future studies and clinical guidance.Respiration (Source: Respiration)
Source: Respiration - April 11, 2022 Category: Respiratory Medicine Source Type: research