Breathlessness and COVID-19: A Call for Research
Breathlessness, also known as dyspnoea, is a debilitating and frequent symptom. Several reports have highlighted the lack of dyspnoea in a subgroup of patients suffering from COVID-19, sometimes referred to as “silent” or “happy hypoxaemia.” Reports have also mentioned the absence of a clear relationship between the clinical severity of the disease and levels of breathlessness reported by patients. The cerebral complications of COVID-19 have been largely demonstrated with a high prevalence of an acute encephalopathy that could possibly affect the processing of afferent signals or top-down modulation of breathless...
Source: Respiration - July 30, 2021 Category: Respiratory Medicine Source Type: research
Pediatric Tuberculosis Disease during Years of High Refugee Arrivals: A 6-Year National Prospective Surveillance Study
Conclusion: The annual pediatric TB incidence rate only varied among foreign-born children and was highest in 2016 when refugee influx peaked in Europe. Importantly, most foreign-born children with TB were diagnosed within 2 years after arrival in Switzerland. Thus, the early period after arrival in Switzerland is associated with a higher risk of TB disease in children, and this should be considered for screening guidance in refugees.Respiration (Source: Respiration)
Source: Respiration - July 29, 2021 Category: Respiratory Medicine Source Type: research
Association between Comorbidities and Preserved Ratio Impaired Spirometry: Using the Korean National Health and Nutrition Examination Survey IV –VI
Conclusion: The number of comorbidities was significantly higher in the PRISm group than in others. Hypertension, diabetes, obesity, ischemic heart disease, chronic renal disease, and thyroid disease were associated with PRISm after adjustment for risk factors.Respiration (Source: Respiration)
Source: Respiration - July 28, 2021 Category: Respiratory Medicine Source Type: research
Pulmonary Rehabilitation in Patients Recovering from COVID-19: Authors ’ Reply
Respiration (Source: Respiration)
Source: Respiration - July 27, 2021 Category: Respiratory Medicine Source Type: research
Endobronchial Valve (Zephyr) Treatment in Homogeneous Emphysema: One-Year Results from the IMPACT Randomized Clinical Trial
Conclusions: Bronchoscopic lung volume reduction with Zephyr valves in subjects with severe homogeneous emphysema and little to no collateral ventilation provides clinically meaningful change from baseline in lung function, quality of life, exercise capacity, dyspnea, and the BODE index at 6 months, with benefits maintained out to 12 months.Respiration (Source: Respiration)
Source: Respiration - July 23, 2021 Category: Respiratory Medicine Source Type: research
The Worsening of Positional Mild Obstructive Sleep Apnea over Time Is Associated with an Increase in Body Weight: Impact on Blood Pressure and Autonomic Nervous System
Conclusions: In patients with positional mild OSA, disease severity, BP, and ANS regulation worse over time. Increased weight was the best predictor for its progression and the loss of positional dependency. Better treatments addressing weight control and consistent follow-up are needed for positional mild OSA.Respiration (Source: Respiration)
Source: Respiration - July 21, 2021 Category: Respiratory Medicine Source Type: research
Musculoskeletal Consequences from COVID-19 and the Importance of Pulmonary Rehabilitation Program
Respiration (Source: Respiration)
Source: Respiration - July 20, 2021 Category: Respiratory Medicine Source Type: research
Use of Incentive Spirometry in Adults following Cardiac, Thoracic, and Upper Abdominal Surgery to Prevent Post-Operative Pulmonary Complications: A Systematic Review and Meta-Analysis
Conclusions: This meta-analysis showed that IS alone likely results in little to no reduction in the number of adult patients with PPCs, in mortality, or in the LHS, following cardiac, thoracic, and upper abdominal surgery.Respiration (Source: Respiration)
Source: Respiration - July 16, 2021 Category: Respiratory Medicine Source Type: research
Diaphragm Pacing in Patients with Spinal Cord Injury: A European Experience
Conclusions: Diaphragm pacing represents an attractive alternative stand-alone treatment or adjunctive therapy compared to MV in patients with high SCI. After a period of acclimation, the patients were able to reduce the daily use of MV, and many could be completely removed from MV.Respiration (Source: Respiration)
Source: Respiration - July 16, 2021 Category: Respiratory Medicine Source Type: research
Interventions to Support Informal Caregivers of People with Chronic Obstructive Pulmonary Disease: A Systematic Literature Review
Conclusion: Interventions have a narrow scope (i.e., education) and have not been specifically designed to support informal caregivers. Current evidence showed positive effects, but high methodological heterogeneity exists. Future studies need to explore caregiver-tailored, taking into consideration gender differences; multicomponent; and flexibly administered interventions to effectively support COPD caregivers.Respiration (Source: Respiration)
Source: Respiration - July 14, 2021 Category: Respiratory Medicine Source Type: research
Portable High-Flow Nasal Oxygen during Walking in Patients with Severe Chronic Obstructive Pulmonary Disease: A Randomized Controlled Trial
Conclusion: In patients with COPD and severe exercise limitation, HFNO delivered by a battery-supplied portable device was more effective in improving walking distance than usual oxygen supplementation.Respiration (Source: Respiration)
Source: Respiration - July 14, 2021 Category: Respiratory Medicine Source Type: research
Cardiac Output Determination in Precapillary Pulmonary Hypertension: A Systematic Review
Conclusions: Further studies evaluating the reliability of thermodilution and the consequences of its use in precapillary pulmonary hypertension patients are necessary. No evidence supports the use of indirect Fick in precapillary pulmonary hypertension. The studied noninvasive methods could not be considered interchangeable with invasive methods. A robust methodology should be used to draw sensible conclusions.Respiration (Source: Respiration)
Source: Respiration - July 13, 2021 Category: Respiratory Medicine Source Type: research
Cutoff Points for Step Count to Predict 1-year All-Cause Mortality in Patients with Idiopathic Pulmonary Fibrosis
Conclusions: Step count, an easily interpretable measurement, was a significant predictor of all-cause mortality in patients with IPF. At the time of diagnosis, a count that exceeded the cutoff point of 3,473 steps/day more than halved mortality. These findings highlight the importance of assessing physical activity in this patient population.Respiration (Source: Respiration)
Source: Respiration - July 9, 2021 Category: Respiratory Medicine Source Type: research
Accuracy and Reproducibility of Endoscopic Ultrasound B-Mode Features for Observer-Based Lymph Nodal Malignancy Prediction
Conclusions: Lymph nodes of ≥8-mm size and preferably even smaller should be aspirated regardless of other B-mode features. Observer disagreement in scoring both small and large lymph nodes suggests it is infeasible to include subjective features for stratification. Future research should focus on (integrating) other (semi)q uantitative values for improving prediction.Respiration (Source: Respiration)
Source: Respiration - June 24, 2021 Category: Respiratory Medicine Source Type: research
Intracardiac EUS-B-Guided FNA for Diagnosing Cardiac Tumors
We describe 2 exceptional diagnostic cases of left atrium tumors in which cardiac surgery was hazardous due to the clinical condition or previous surgical interventions. During EUS-B-guided fine-needle aspiration (FNA), the left atrial masses were successfully and safely sampled, revealing a Burkitt lymphoma and a synovial sarcoma. FNA including cell block analysis enabled specific tumor diagnosis and molecular subtyping. Our findings suggest that in selected cases, linear endosonography qualifies as a minimally invasive technique for intracardiac tumor diagnostics.Respiration (Source: Respiration)
Source: Respiration - June 24, 2021 Category: Respiratory Medicine Source Type: research
