The Primary Ciliary Dyskinesia Computed Tomography Score in Adults with Bronchiectasis: A Derivation und Validation Study
Conclusions: The PCD-CT score provides the first validated CT score for PCD and helps physicians in identifying adult bronchiectasis patients who require further diagnostic workup.Key message: The PCD-CT score provides the first validated CT score to assist physicians in identifying adult bronchiectasis patients who require a further diagnostic workup for PCD. It potentially improves earlier recognition of this rare and underdiagnosed disease.Respiration (Source: Respiration)
Source: Respiration - April 23, 2021 Category: Respiratory Medicine Source Type: research

Small Airway Dysfunction in Asthma Is Associated with Perceived Respiratory Symptoms, Non-Type 2 Airway Inflammation, and Poor Responses to Therapy
Conclusions: This study indicates that SAD in asthma predisposes patients to greater dyspnea intensity and chest tightness during bronchoconstriction. SAD patients with asthma are characterized by non-type 2 inflammation that may account for poor responsiveness to therapy.Respiration (Source: Respiration)
Source: Respiration - April 23, 2021 Category: Respiratory Medicine Source Type: research

Validity of the 6-Minute Walk Test in Patients with End-Stage Lung Diseases Wearing an Oronasal Surgical Mask in Times of the COVID-19 Pandemic
Conclusion: Wearing an oronasal surgical mask did not affect the 6MWDs of patients with advanced lung diseases. Therefore, a masked 6MWT appears to provide a reliable examination of functional exercise capacity in this cohort.Respiration (Source: Respiration)
Source: Respiration - April 20, 2021 Category: Respiratory Medicine Source Type: research

Baseline Characteristics and Survival of an Australian Interstitial Pneumonia with Autoimmune Features Cohort
Conclusions: We identified IPAF as a heterogeneous phenotype that overlaps considerably with CTD-ILD. Disease severity, PH, and ILD-MDM diagnosis were more powerful predictors of survival outcomes than meeting the IPAF criteria.Respiration (Source: Respiration)
Source: Respiration - April 19, 2021 Category: Respiratory Medicine Source Type: research

Fully Automated Segmentation of Pulmonary Fibrosis Using Different Software Tools
Conclusions: In terms of segmentation of pulmonary fibrosis, LUFIT as a shape model-based segmentation software tool is superior to the threshold-based YACTA, tool, since the density of (severe) fibrosis is similar to that of the surrounding soft tissues. Therefore, shape modeling as used in LUFIT may serve as a valid tool in the quantification of IPF, since this mainly affects the subpleural space.Respiration (Source: Respiration)
Source: Respiration - April 15, 2021 Category: Respiratory Medicine Source Type: research

Ergogenic Value of Oxygen Supplementation in Patients with Idiopathic Pulmonary Fibrosis with Isolated Exertional Oxygen Desaturation
Respiration (Source: Respiration)
Source: Respiration - April 13, 2021 Category: Respiratory Medicine Source Type: research

Concurrence of 1- and 3-Min Sit-to-Stand Tests with the 6-Min Walk Test in Idiopathic Pulmonary Fibrosis
Conclusion: The correlations found between the 2 STSTs and the 6-MWT suggest that STSTs may be of interest to assess displacement and exercise-induced changes in SpO2 in IPF patients.Respiration (Source: Respiration)
Source: Respiration - April 13, 2021 Category: Respiratory Medicine Source Type: research

Hypercapnia in COPD Patients Undergoing Endobronchial Ultrasound under Local Anaesthesia and Analgosedation: A Prospective Controlled Study Using Continuous Transcutaneous Capnometry
Conclusion: A relevant proportion of patients reached their peak-pCO2 after the end of intervention. We recommend using capnometry at least for patients with known COPD. Flexible EBUS in analgosedation can be safely performed in patients with advanced COPD. For patients with advanced COPD, a postprocedural observation time of 60 min was sufficient.Respiration (Source: Respiration)
Source: Respiration - April 13, 2021 Category: Respiratory Medicine Source Type: research

Exercise Testing in Idiopathic Pulmonary Fibrosis: Expanding Our Options
Respiration (Source: Respiration)
Source: Respiration - April 13, 2021 Category: Respiratory Medicine Source Type: research

Medical Thoracoscopy Implementation after a European Respiratory Society Course Held from 2003 to 2016: A Survey
Conclusions: Real-life data of our survey suggest that more than half of the responders have implemented the technique or modified their practice according to the skills they got from the course.Respiration (Source: Respiration)
Source: Respiration - April 13, 2021 Category: Respiratory Medicine Source Type: research

A Before-and-After Study of Evidence-Based Recommendations for On-Call Bronchoscopy
Conclusion: The introduction of recommendations for on-call bronchoscopy led to a significant decline of on-call bronchoscopies without negatively affecting outcome. More evidence is needed in on-call bronchoscopy, especially for ICU patients with intrinsic higher complication rates.Respiration (Source: Respiration)
Source: Respiration - April 13, 2021 Category: Respiratory Medicine Source Type: research

Variable Learning Curve of Basic Rigid Bronchoscopy in Trainees
Conclusions: Trainees acquire RB skills at a variable pace, and RIGID-TASC can be used to assess learning curve of IP trainees in clinical settings.Respiration (Source: Respiration)
Source: Respiration - April 13, 2021 Category: Respiratory Medicine Source Type: research

Efficacy and Safety of Cone-Beam Computed Tomography-Derived Augmented Fluoroscopy Combined with Endobronchial Ultrasound in Peripheral Pulmonary Lesions
Conclusions: TBB using a combination of CBCT-AF and EBUS resulted in a satisfactory diagnostic yield and safety.Respiration (Source: Respiration)
Source: Respiration - April 12, 2021 Category: Respiratory Medicine Source Type: research

The Usefulness of a Simple Classification for Bronchoscopic Findings for Diagnosis of Peripheral Pulmonary Tumour
Conclusions: Our simple classification based on the appearance of stenosis and LBL in PPT may facilitate pathological diagnosis.Respiration (Source: Respiration)
Source: Respiration - April 9, 2021 Category: Respiratory Medicine Source Type: research

Reduction in Hospitalizations for Respiratory Diseases during the First COVID-19 Wave in Greece
Conclusion: The significant reduction in respiratory admissions in 2020 raises the reasonable question of whether some patients may have avoided seeking medical attention during the COVID-19 pandemic and suggests an urgent need for transformation of healthcare systems during the pandemic to offer appropriate management of respiratory diseases other than COVID-19.Respiration (Source: Respiration)
Source: Respiration - April 7, 2021 Category: Respiratory Medicine Source Type: research