Estimating chikungunya virus transmission parameters and vector control effectiveness highlights key factors to mitigate arboviral disease outbreaks
ConclusionsThe results of the different simulations underline the relative importance of each variable and can be useful to stakeholders when designing context-based intervention strategies. The findings emphasize the importance of, and advocate for early detection of imported cases and timely biological confirmation of autochthonous cases to ensure timely vector control measures, supporting the implementation and the maintenance of sustainable surveillance systems. (Source: PLoS Neglected Tropical Diseases)
Source: PLoS Neglected Tropical Diseases - March 4, 2022 Category: Tropical Medicine Authors: Fr édéric Jourdain Source Type: research

Malnutrition, anemia, micronutrient deficiency and parasitic infections among schoolchildren in rural Tanzania
Conclusions/SignificanceMalnutrition, anemia and micronutrient deficiency still pose a significant health burden among schoolchildren living in rural Tanzania. To effectively tackle this burden, health interventions such as deworming, micronutrient supplementation, vector control, health education and access to clean water and improved sanitation should be strengthened and made sustainable. (Source: PLoS Neglected Tropical Diseases)
Source: PLoS Neglected Tropical Diseases - March 4, 2022 Category: Tropical Medicine Authors: Emmanuel C. Mrimi Source Type: research

High yield of retrospective active case finding for leprosy in Comoros
by Nimer Ortu ño-Gutiérrez, Aboubacar Mzembaba, Abdallah Baco, Sofie M. Braet, Assoumani Younoussa, Zahara Salim, Mohamed Amidy, Saverio Grillone, Aouladi Said, Bouke C. de Jong, Jan Hendrik Richardus, Epco Hasker (Source: PLoS Neglected Tropical Diseases)
Source: PLoS Neglected Tropical Diseases - March 3, 2022 Category: Tropical Medicine Authors: Nimer Ortu ño-Gutiérrez Source Type: research

From dogs to bats: Concerns regarding vampire bat-borne rabies in Brazil
by Marco Aur élio Horta, Leandro Augusto Ledesma, Wlamir Correa Moura, Elba Regina Sampaio Lemos (Source: PLoS Neglected Tropical Diseases)
Source: PLoS Neglected Tropical Diseases - March 3, 2022 Category: Tropical Medicine Authors: Marco Aur élio Horta Source Type: research

Human rights as a framework for eliminating female genital schistosomiasis
This article analyzes human rights–based approaches to FGS control and elimination efforts, outlin ing several areas for forward-looking reforms to health policy, programing, and practice. Building from the lessons learned in applying human rights–based approaches to advance progress on other NTDs, this analysis seeks to provide the NTD community with shared understanding around international l egal obligations to engage SRHR advocates and draw heightened attention to FGS. Such human rights–based approaches to FGS control and elimination can help to reduce stigma and improve care for the millions of women and girls c...
Source: PLoS Neglected Tropical Diseases - March 3, 2022 Category: Tropical Medicine Authors: Caitlin R. Williams Source Type: research

Sero-epidemiological survey of < i > Coxiella burnetii < /i > in livestock and humans in Tana river and garissa counties in Kenya
by Damaris Mwololo, Daniel Nthiwa, Philip Kitala, Tequiero Abuom, Martin Wainaina, Salome Kairu-Wanyoike, Johanna F. Lindahl, Enoch Ontiri, Salome Bukachi, Ian Njeru, Joan Karanja, Rosemary Sang, Delia Grace, Bernard Bett BackgroundCoxiella burnetii is a widely distributed pathogen, but data on its epidemiology in livestock, and human populations remains scanty, especially in developing countries such as Kenya. We used the One Health approach to estimate the seroprevalance ofC.burnetii in cattle, sheep, goats and human populations in Tana River county, and in humans in Garissa county, Kenya. We also identified potential de...
Source: PLoS Neglected Tropical Diseases - March 3, 2022 Category: Tropical Medicine Authors: Damaris Mwololo Source Type: research

Conceptual model of low-cost improvised bubble continuous positive airway pressure device for adults and its potential use in the COVID-19 pandemic
by Himal Kharel, Zeni Kharel, Samikchhya Keshary Bhandari Low-cost improvised continuous positive airway pressure (CPAP) device is safe and efficacious in neonatal respiratory distress. There is a great necessity for similar device in adults, and this has been especially made apparent by the recent Coronavirus Disease 2019 (COVID-19) pandemic, which is u nmasking the deficiencies of healthcare system in several low-resource countries. We propose a simplified and inexpensive model of improvised CPAP in adults using locally available resources including aquarium air pumps and a novel pressure release mechanism. Although the...
Source: PLoS Neglected Tropical Diseases - March 3, 2022 Category: Tropical Medicine Authors: Himal Kharel Source Type: research

In vivo reflectance confocal microscopy, dermoscopy, high-frequency ultrasonography, and histopathology features in a case of chromoblastomycosis
by Gabriela A. Giraldelli, J éssica L. C. S. Baka, Rosane Orofino-Costa, Juan Piñeiro-Maceira, Elisa Barcaui, Carlos B. Barcaui (Source: PLoS Neglected Tropical Diseases)
Source: PLoS Neglected Tropical Diseases - March 3, 2022 Category: Tropical Medicine Authors: Gabriela A. Giraldelli Source Type: research

Efficacy and community-effectiveness of insecticide treated nets for the control of visceral leishmaniasis: A systematic review
Conclusions of this review are (1) combining insecticide impregnated bednets, as targeted interventions, with another vector control measure, particularly indoor residual spraying, and in conjunction with case detection, could be the way forward to controlling V L in resource limited settings. (2) Given the current low incidence of VL in SEA, it can be difficult to further research the community effectiveness of those control measures in reducing VL. (Source: PLoS Neglected Tropical Diseases)
Source: PLoS Neglected Tropical Diseases - March 2, 2022 Category: Tropical Medicine Authors: Carlos Alberto Montenegro-Qui ñonez Source Type: research

Long-term Chikungunya sequelae and quality of life 2.5 years post-acute disease in a prospective cohort in Cura çao
by Churnalisa Doran, Jelte Elsinga, Ante Fokkema, Kevin Berenschot, Izzy Gerstenbluth, Ashley Duits, Norediz Lourents, Yaskara Halabi, Johannes Burgerhof, Ajay Bailey, Adriana Tami BackgroundLittle is known about the persistence and impact of non-rheumatic symptoms after acute chikungunya disease. We have studied the clinical presentation and long-term impact of rheumatic and non-rheumatic symptoms on health related quality of life (QoL) 2.5 years after disease onset. Additionally, the validity of the Cura çao Long-Term Chikungunya Sequelae (CLTCS) score in classifying disease severity over time was evaluated. Methodology...
Source: PLoS Neglected Tropical Diseases - March 1, 2022 Category: Tropical Medicine Authors: Churnalisa Doran Source Type: research

Factors associated with in-hospital mortality of adult tetanus patients –a multicenter study from Bangladesh
ConclusionOlder age and short onset time are the two most important determinants of in-hospital mortality of tetanus patients. Hence, these patients require enhanced emphasis and care. (Source: PLoS Neglected Tropical Diseases)
Source: PLoS Neglected Tropical Diseases - March 1, 2022 Category: Tropical Medicine Authors: Md. Abdullah Saeed Khan Source Type: research

Population-based assessment of factors influencing antibiotic prescribing for adults with dengue infection in Taiwan
ConclusionsIn addition to patient and physician demographic characteristics, contextual factors such as care setting and during epidemics significantly influenced prescription of antibiotics. Characterization of prescribing patterns should help direct programs to curb antibiotic prescribing. (Source: PLoS Neglected Tropical Diseases)
Source: PLoS Neglected Tropical Diseases - February 28, 2022 Category: Tropical Medicine Authors: Chia-En Lien Source Type: research

Positive-case follow up for lymphatic filariasis after a transmission assessment survey in Haiti
Conclusions/SignificanceOverall, both purposive and random sampling methods were reasonable and achievable methods of TAS follow-up in resource-limited settings. Both methods identified additional CFA-positives in close geographic proximity to LF-positive children found by TAS, and both identified strong signs of ongoing transmission in the large urban commune of Miragoane. These findings will help inform standardized guidelines for post-TAS surveillance. (Source: PLoS Neglected Tropical Diseases)
Source: PLoS Neglected Tropical Diseases - February 25, 2022 Category: Tropical Medicine Authors: Marisa A. Hast Source Type: research

Opportunity or catastrophe? effect of sea salt on host-parasite survival and reproduction
This study examined the effect o f artificial seawater on host-parasite interactions using a freshwater snail host,Biomphalaria alexandrina, and the human trematode parasiteSchistosoma mansoni. To evaluate the impact of increasing salinity on disease transmission four variables were analyzed: snail survival, snail reproduction, infection prevalence, and the survival of the parasite infective stage (cercariae). We found a decrease in snail survival, snail egg mass production, and snail infection prevalence as salinity increases. However, cercarial survival peaked at an intermediate salinity value. Our results suggest that s...
Source: PLoS Neglected Tropical Diseases - February 24, 2022 Category: Tropical Medicine Authors: Ao Yu Source Type: research

Histoplasmosis in Africa: Current perspectives, knowledge gaps, and research priorities
ConclusionsDespite a subtle increase in identifying histoplasmosis cases in Africa, it remains underdiagnosed and neglected in some parts of the continent. Increasing awareness and training among healthcare workers, bridging diagnostic and therapeutic gaps, and encouraging more research in Africa are crucial to improve the current perspectives of histoplasmosis in Africa. (Source: PLoS Neglected Tropical Diseases)
Source: PLoS Neglected Tropical Diseases - February 24, 2022 Category: Tropical Medicine Authors: Bright K. Ocansey Source Type: research