Expression of Concern: A Potential Role for the Interaction of < i > Wolbachia < /i > Surface Proteins with the < i > Brugia malayi < /i > Glycolytic Enzymes and Cytoskeleton in Maintenance of Endosymbiosis
by The PLOS Neglected Tropical Diseases Editors (Source: PLoS Neglected Tropical Diseases)
Source: PLoS Neglected Tropical Diseases - December 29, 2023 Category: Tropical Medicine Authors: The PLOS Neglected Tropical Diseases Editors Source Type: research
Conducting epidemiological studies on snakebite in nomadic populations: A methodological paper
ConclusionHighly mobile populations require specific considerations in selecting or creating sampling frames and sampling units for epidemiological research. Snakebite risk has a strong spatial component and using census-based sampling frames would be inappropriate in nomadic populations. We propose using open-source satellite imaging and geographic information systems to improve the conduct of epidemiological research in these populations. (Source: PLoS Neglected Tropical Diseases)
Source: PLoS Neglected Tropical Diseases - December 28, 2023 Category: Tropical Medicine Authors: George O. Oluoch Source Type: research
Stigma associated with cutaneous and mucocutaneous leishmaniasis: A systematic review
ConclusionsThere are various manifestations of stigma associated with CL and MCL. This review highlights the lack of knowledge on the structural stigma associated with CL, the lack of stigma interventions and the need for a unique stigma tool to measure stigma associated with CL and MCL. (Source: PLoS Neglected Tropical Diseases)
Source: PLoS Neglected Tropical Diseases - December 28, 2023 Category: Tropical Medicine Authors: Hasara Nuwangi Source Type: research
Prevalence and risk factors associated with < i > Haemophilus ducreyi < /i > cutaneous ulcers in Cameroon
The objective of this study was to determine the prevalence ofHD as cause of cutaneous ulcers, investigate its presence in asymptomatic individuals and identify associated risk factors. A cross-sectional study was conducted in yaws endemic districts of Cameroon. Participants included people presenting yaws-like ulcers and asymptomatic individuals. Swab samples were collected from each participant and tested forHD andTreponema pallidum (TP) using an established qPCR method. Additionally, demographic, habitat, proximity, and hygiene characteristics were collected using a structured questionnaire. A total of 443 individuals p...
Source: PLoS Neglected Tropical Diseases - December 27, 2023 Category: Tropical Medicine Authors: Philippe Ndzomo Source Type: research
Non-linear associations between meteorological factors, ambient air pollutants and major mosquito-borne diseases in Thailand
ConclusionsThis study found protective and enhancing effects of meteorological and ambient air pollutant factors on mosquito-borne diseases burdens in Thailand. Further studies should employ these factors to understand and predict risk factors associated with mosquito-borne disease transmission. (Source: PLoS Neglected Tropical Diseases)
Source: PLoS Neglected Tropical Diseases - December 27, 2023 Category: Tropical Medicine Authors: Pranav Tewari Source Type: research
Design of the Global Health chemical diversity library v2 for screening against infectious diseases
by Caroline Wilson, J. Mark F. Gardner, David W. Gray, Beatriz Baragana, Paul G. Wyatt, Alex Cookson, Stephen Thompson, Cesar Mendoza-Martinez, Michael J. Bodkin, Ian H. Gilbert, Gary J. Tarver
There is a need for novel chemical matter for phenotypic and target-based screens to find starting points for drug discovery programmes in neglected infectious diseases and non-hormonal contraceptives that disproportionately affect Low- and Middle-Income Countries (LMICs). In some disease areas multiple screens of corporate and other libraries have been carried out, giving rise to some valuable starting points and leading to precli...
Source: PLoS Neglected Tropical Diseases - December 27, 2023 Category: Tropical Medicine Authors: Caroline Wilson Source Type: research
Dynamics of chikungunya virus transmission in the first year after its introduction in Brazil: A cohort study in an urban community
by Ros ângela O. Anjos, Moyra M. Portilho, Leile Camila Jacob-Nascimento, Caroline X. Carvalho, Patrícia S. S. Moreira, Gielson A. Sacramento, Nivison R. R. Nery Junior, Daiana de Oliveira, Jaqueline S. Cruz, Cristiane W. Cardoso, Hernan D. Argibay, Kenneth S. Plante, Jessica A. Plante, Scott C. Weaver, Uriel D. Kitron, Mitermayer G. Reis, Albert I. Ko, Federico Costa, Guilherme S. Ribeiro
BackgroundThe first chikungunya virus (CHIKV) outbreaks during the modern scientific era were identified in the Americas in 2013, reaching high attack rates in Caribbean countries. However, few cohort studies have been performed to cha...
Source: PLoS Neglected Tropical Diseases - December 27, 2023 Category: Tropical Medicine Authors: Ros ângela O. Anjos Source Type: research
Epidemiological characteristics and spatio-temporal aggregation of severe fever with thrombocytopenia syndrome in Jinan City, China, 2018 –2022
by Shang Gao, Xingyi Geng, Qingbin Lu, Shanzheng Wu, Zhaoxia Shan, Caiyun Chang
BackgroundSevere fever with thrombocytopenia syndrome (SFTS) has become a significant public health issue in Jinan City. However, the analysis of epidemiological characteristics and spatio-temporal clustering of SFTS in Jinan has not been studied yet. MethodsSFTS data from 2018 −2022 in Jinan City were obtained from the China Information System for Disease Control and Prevention. Global spatial autocorrelation and local spatial autocorrelation analyses were performed using ArcGIS 10.2 software, and spatiotemporal hotspot area detection was ca...
Source: PLoS Neglected Tropical Diseases - December 22, 2023 Category: Tropical Medicine Authors: Shang Gao Source Type: research
Scabies prevalence and its associated factors among prisoners in southern Ethiopia: An institution-based analytical cross-sectional study
by Efa Ambaw Bogino, Beshada Zerfu Woldegeorgis, Lantesil Wondewosen, Blen Kassahun Dessu, Mohammed Suleiman Obsa, Lolamo Kelbiso, Teketel Ermias Galtore, Woldu Kidane, Abraham Getachew Kelbore
BackgroundScabies is an ectoparasitic infestation that can easily spread during close human contact and in overcrowded areas such as prisons and public places where sanitation is a problem. Globally, as many as 300 million people are infested with scabies each year. Within Ethiopia, its burden in institutions like prisons is not well-studied. As a consequence, we sought to estimate the prevalence of scabies and also identify factors...
Source: PLoS Neglected Tropical Diseases - December 22, 2023 Category: Tropical Medicine Authors: Efa Ambaw Bogino Source Type: research
Retraction: Kinetics of Antibody Response in BALB/c and C57BL/6 Mice Bitten by < i > Phlebotomus papatasi < /i >
by The PLOS Neglected Tropical Diseases Editors (Source: PLoS Neglected Tropical Diseases)
Source: PLoS Neglected Tropical Diseases - December 22, 2023 Category: Tropical Medicine Authors: The PLOS Neglected Tropical Diseases Editors Source Type: research
Prevalence and risk factors for human leptospirosis at a hospital serving a pastoralist community, Endulen, Tanzania
ConclusionsWe identified leptospirosis in approximately one in twelve patients attending hospital with fever from this rural community. Interventions that reduce risks associated with milking livestock may reduce human infections. (Source: PLoS Neglected Tropical Diseases)
Source: PLoS Neglected Tropical Diseases - December 20, 2023 Category: Tropical Medicine Authors: Michael J. Maze Source Type: research
Effects of cattle on vector-borne disease risk to humans: A systematic review
This study was performed according to the PRISMA 2020 extension guidelines for systematic review. After screening 470 peer-reviewed articles published between 1999 –2019 using the databases Web of Science Core Collection, PubMed Central, CABI Global Health, and Google Scholar, and utilizing forward and backward search techniques, we identified 127 papers that met inclusion criteria. Results of the systematic review indicate that cattle can be beneficial or h armful to human health with respect to VBDs depending on vector and pathogen ecology and livestock management practices. Cattle can increase risk of exposure to infe...
Source: PLoS Neglected Tropical Diseases - December 19, 2023 Category: Tropical Medicine Authors: Sulagna Chakraborty Source Type: research
Comparison of clinical and laboratory characteristics between severe and non-severe dengue in paediatrics
ConclusionIn paediatric patients, severe dengue is associated with specific clinical indicators, including lethargy, low systolic blood pressure, prolonged capillary refill time (CRT), and the presence of ascites and hepatomegaly. Identifying these clinical features early is crucial for primary care physicians, as it enables accurate diagnosis and timely intervention to manage severe dengue effectively. (Source: PLoS Neglected Tropical Diseases)
Source: PLoS Neglected Tropical Diseases - December 19, 2023 Category: Tropical Medicine Authors: Nurul Liyana Idrus Source Type: research
Genomic survey maps differences in the molecular complement of vesicle formation machinery between < i > Giardia intestinalis < /i > assemblages
In this study, we explored the necessary machinery for the formation of vesicles and cargo transport in 89 Canadian isolates of assemblage A and BG.intestinalis. Considerable variability within the molecular complement of the endolysosomal ESCRT protein machinery, adaptor coat protein complexes, and ARF regulatory system have previously been reported. Here, we confirm inter-assemblage, but find no intra-assemblage variation within the trafficking systems examined. This variation includes losses of subunits belonging to the ESCRTIII as well as novel lineage specific duplications in components of the COPII machinery, ARF1, a...
Source: PLoS Neglected Tropical Diseases - December 18, 2023 Category: Tropical Medicine Authors: Shweta V. Pipaliya Source Type: research
Assessment of biomarkers and clinical parameters as predictors of survival in patients with chagasic heart failure
ConclusionDespite the presence of a chronic inflammatory process, the evaluated inflammatory biomarkers in this cohort were not predictive of survival in patients with chagasic HF with reduced ejection fraction (HFrEF). However, reduced LVEF, elevated BNP, adiponectin levels, and troponin T were identified as predictors of lower survival in these patients. (Source: PLoS Neglected Tropical Diseases)
Source: PLoS Neglected Tropical Diseases - December 18, 2023 Category: Tropical Medicine Authors: Edimar Alcides Bocchi Source Type: research
