Pediatric nephrology in under-resourced areas: one pill will not cure all ills —economics and awareness are both important factors
(Source: Pediatric Nephrology)
Source: Pediatric Nephrology - August 1, 2023 Category: Urology & Nephrology Source Type: research
Publisher Correction: How to define and assess the clinically significant causes of hematuria in childhood
(Source: Pediatric Nephrology)
Source: Pediatric Nephrology - August 1, 2023 Category: Urology & Nephrology Source Type: research
Weight loss and metabolic acidosis in a neonate: Questions
(Source: Pediatric Nephrology)
Source: Pediatric Nephrology - August 1, 2023 Category: Urology & Nephrology Source Type: research
The urological evaluation and management of neurogenic bladder in children and adolescents —what every pediatric nephrologist needs to know
AbstractNeurogenic bladder (NGB) is an encompassing term that includes multiple causes of bladder dysfunction linked to a congenital or acquired neurological condition that adversely impacts the innervation of the lower urinary tract. Multiple static or progressive conditions can be associated with NGB in pediatric and adolescent patients. Currently, spinal dysraphism (i.e., spina bifida) is one of the most common etiologies, which occurs in 3 –4 per 10,000 live births in developed nations. Abnormal bladder dynamics can lead to kidney damage secondary to high pressures or recurrent infections, as well as urinary incontin...
Source: Pediatric Nephrology - July 31, 2023 Category: Urology & Nephrology Source Type: research
Screening for protein energy wasting in children with chronic kidney disease using dual energy x-ray absorptiometry as an additional tool
ConclusionsPEW prevalence in CKD was high. Both prevalence and severity were higher in advanced CKD. LBMr was a highly sensitive marker to detect PEW. LBMr seen in some children with CKD who were negative for other markers could represent subclinical PEW.Graphical AbstractA higher resolution version of the Graphical abstract is available asSupplementary information (Source: Pediatric Nephrology)
Source: Pediatric Nephrology - July 29, 2023 Category: Urology & Nephrology Source Type: research
Yield of diagnostic testing in evaluating etiology and end organ effects of pediatric hypertension
ConclusionA simplified secondary hypertension workup should be considered for all hypertensive children and adolescents. High yield investigations include a kidney ultrasound, lipid profile for overweight/obese children, and echocardiograms for assessment of target-organ damage. Further testing could be considered based on results of initial investigations for the most cost-effective management.Graphical abstractA higher resolution version of the Graphical abstract is available asSupplementary information (Source: Pediatric Nephrology)
Source: Pediatric Nephrology - July 29, 2023 Category: Urology & Nephrology Source Type: research
Use of the Seraph ® 100 Microbind® Affinity Blood Filter in an adolescent patient with disseminated adenoviral disease
ConclusionsThis adolescent kidney transplant patient with disseminated ADV infection tolerated in-line treatment with Seraph ® 100 without major clinical adverse events related to the adsorber, and had resolution of her ADV infection and good clinical recovery. (Source: Pediatric Nephrology)
Source: Pediatric Nephrology - July 28, 2023 Category: Urology & Nephrology Source Type: research
Multidisciplinary management of people with spina bifida across the lifespan
AbstractThe average worldwide prevalence of neural tube defects (NTDs) is 1.0 per 1000 births. Its development is multifactorial due to genetic and non-genetic factors. Spina bifida (SB) is one of main representatives of NTD. The spinal cord lesion level is the main determinant of the level of paralysis, numbness, and difficulties with bladder/bowel functions. Myelomeningocele prenatal repair reduces hydrocephalus and hindbrain herniation and improves motor function. The severity of hydrocephalus is associated with poorer neurodevelopmental outcomes whether operated on prenatally or after birth. People with SB tend to have...
Source: Pediatric Nephrology - July 28, 2023 Category: Urology & Nephrology Source Type: research
Pioglitazone, a PPAR-y agonist, as one of the new therapeutic candidates for C3 glomerulopathy
ConclusionsIn this patient affected by C3G, pioglitazone proved effective in reducing proteinuria levels. (Source: Pediatric Nephrology)
Source: Pediatric Nephrology - July 26, 2023 Category: Urology & Nephrology Source Type: research
Is collagen X marker (CXM) a useful index of growth velocity in children with chronic kidney disease?
(Source: Pediatric Nephrology)
Source: Pediatric Nephrology - July 26, 2023 Category: Urology & Nephrology Source Type: research
Anti-nephrin antibodies in steroid-sensitive nephrotic syndrome in Japanese children
(Source: Pediatric Nephrology)
Source: Pediatric Nephrology - July 26, 2023 Category: Urology & Nephrology Source Type: research
Eculizumab in STEC-HUS: a paradigm shift in the management of pediatric patients with neurological involvement
ConclusionWe present a case series of four children with STEC-HUS and CNS involvement, managed with eculizumab only, in lieu of plasma exchange (as per our previous policy). The marked improvement in symptoms in our cohort supports the use of eculizumab, rather than plasma exchange in the CNS involvement of STEC-HUS. (Source: Pediatric Nephrology)
Source: Pediatric Nephrology - July 25, 2023 Category: Urology & Nephrology Source Type: research
Is the renal score predictive for kidney replacement therapy in pediatric patients with crush syndrome?
ConclusionsWe suggest that if a similar disaster occurs in the future, an easy and applicable renal scoring system can contribute to the prognosis by providing appropriate and early treatment for KRT.Graphical abstractA higher resolution version of the Graphical abstract is available asSupplementary information (Source: Pediatric Nephrology)
Source: Pediatric Nephrology - July 25, 2023 Category: Urology & Nephrology Source Type: research
Eculizumab in STEC-HUS: a paradigm shift in the management of pediatric patients with neurological involvement
ConclusionWe present a case series of four children with STEC-HUS and CNS involvement, managed with eculizumab only, in lieu of plasma exchange (as per our previous policy). The marked improvement in symptoms in our cohort supports the use of eculizumab, rather than plasma exchange in the CNS involvement of STEC-HUS. (Source: Pediatric Nephrology)
Source: Pediatric Nephrology - July 25, 2023 Category: Urology & Nephrology Source Type: research
Is the renal score predictive for kidney replacement therapy in pediatric patients with crush syndrome?
ConclusionsWe suggest that if a similar disaster occurs in the future, an easy and applicable renal scoring system can contribute to the prognosis by providing appropriate and early treatment for KRT.Graphical abstractA higher resolution version of the Graphical abstract is available asSupplementary information (Source: Pediatric Nephrology)
Source: Pediatric Nephrology - July 25, 2023 Category: Urology & Nephrology Source Type: research
