Eyes sees what mind knows —a very rare cause of hydroureteronephrosis in a 12-year-old boy: Answers
(Source: Pediatric Nephrology)
Source: Pediatric Nephrology - September 22, 2023 Category: Urology & Nephrology Source Type: research

A typical clinical manifestation of atypical underlying diagnosis: Questions
(Source: Pediatric Nephrology)
Source: Pediatric Nephrology - September 22, 2023 Category: Urology & Nephrology Source Type: research

A typical clinical manifestation of atypical underlying diagnosis: Answers
(Source: Pediatric Nephrology)
Source: Pediatric Nephrology - September 22, 2023 Category: Urology & Nephrology Source Type: research

Eyes sees what mind knows —a very rare cause of hydroureteronephrosis in a 12-year-old boy: Questions
(Source: Pediatric Nephrology)
Source: Pediatric Nephrology - September 22, 2023 Category: Urology & Nephrology Source Type: research

Association of clinical characteristics with urine uromodulin in children with chronic kidney disease
ConclusionsAmong children with CKD, older age is significantly associated with lower Umod/Cr, independent of eGFR. Further studies are needed to comprehensively evaluate age-specific reference ranges for urine uromodulin and to evaluate the longitudinal relationship of uromodulin with both age and eGFR in children with CKD.Graphical abstractA higher resolution version of the Graphical abstract is available asSupplementary information (Source: Pediatric Nephrology)
Source: Pediatric Nephrology - September 22, 2023 Category: Urology & Nephrology Source Type: research

Urine specific gravity, pyuria, and neutrophil gelatinase-associated lipocalin for identifying urinary tract infection in young children
ConclusionsUrine SG can affect the diagnostic performance of pyuria for detecting UTI and uNGAL might be helpful for identifying UTI regardless of urine SG in young children.Graphical abstractA higher resolution version of the Graphical abstract is available asSupplementary information (Source: Pediatric Nephrology)
Source: Pediatric Nephrology - August 30, 2023 Category: Urology & Nephrology Source Type: research

Cytopenias in pediatric kidney transplant recipients: preceding factors and clinical consequences
ConclusionsPosttransplant infections are substantial contributors to developing posttransplant cytopenias. Preemptive transplantation appears to reduce risk of late neutropenia, the accompanying reduction in immunosuppressive therapy, and the ensuing risk of graft rejection. An alternative response to neutropenia, possibly using granulocyte colony stimulating factor, may diminish graft rejection.Graphical abstractA higher resolution version of the Graphical abstract is available asSupplementary information (Source: Pediatric Nephrology)
Source: Pediatric Nephrology - August 30, 2023 Category: Urology & Nephrology Source Type: research

Predicting outcomes in children with congenital anomalies of the kidney and urinary tract
ConclusionUsing a large combined CAKUT cohort we identified risk factors for CKD. Our prediction model provides the first steps towards a risk-stratified clinical pathway.Graphical abstractA higher resolution version of the Graphical abstract is available asSupplementary information (Source: Pediatric Nephrology)
Source: Pediatric Nephrology - August 30, 2023 Category: Urology & Nephrology Source Type: research

Associations of longitudinal height and weight with clinical outcomes in pediatric kidney replacement therapy: results from the ESPN/ERA Registry
ConclusionsShort and tall stature and being underweight were associated with a lower likelihood of receiving a kidney allograft. Mortality risk was higher among pediatric KRT patients with a short stature or those being underweight or obese. Our results highlight the need for careful nutritional management and multidisciplinary approach for these patients.Graphical abstractA higher resolution version of the Graphical abstract is available asSupplementary information (Source: Pediatric Nephrology)
Source: Pediatric Nephrology - August 30, 2023 Category: Urology & Nephrology Source Type: research

Antenatally detected urinary tract dilatation: long-term outcome
AbstractThis review provides updated knowledge on the long-term outcomes among children with antenatally diagnosed urinary tract dilatation (UTD), previously often referred to as antenatal hydronephrosis. Different definitions of UTD exist, which makes comparison between studies and generalized conclusions difficult. Roughly, one-third of antenatally diagnosed UTD, defined as a renal pelvis anterior posterior diameter (APD) of  ≥ 4 mm in the second trimester and/or ≥ 7 mm in the third trimester, will resolve before birth, another third will resolve within the first years of life, and in the remaining cases, U...
Source: Pediatric Nephrology - August 30, 2023 Category: Urology & Nephrology Source Type: research

Postoperative management and complications after abdominal surgery in children receiving peritoneal dialysis
ConclusionsOur findings demonstrated that PD could be resumed within 48  h of inguinal hernia repair with no PD fluid leakage or hernia recurrence in pediatric patients. In addition, resuming PD 3 days after a laparoscopic procedure with less than half of the usual dialysate volume might reduce the risk of PD fluid leakage.Graphical abstractA higher resolution version of the Graphical abstract is available asSupplementary information (Source: Pediatric Nephrology)
Source: Pediatric Nephrology - August 30, 2023 Category: Urology & Nephrology Source Type: research

Changes in bone turnover markers after discontinuing long-term glucocorticoid administration in children with idiopathic nephrotic syndrome: a multicenter retrospective observational study
ConclusionsDecreased BTMs can rise within a few months of discontinuing long-term glucocorticoid administration. When the administered glucocorticoid dose is low, changes in BTMs may be small.Graphical abstractA higher resolution version of the Graphical abstract is available asSupplementary information (Source: Pediatric Nephrology)
Source: Pediatric Nephrology - August 30, 2023 Category: Urology & Nephrology Source Type: research

Acute kidney injury in critically ill children with COVID-19 and MIS-C
ConclusionsAKI in the COVID-19 and MIS-C patient groups is related with increased mortality and extended hospitalization, according to the findings. These statistics imply that identifying and preventing risk factors is necessary.Graphical abstractA higher resolution version of the Graphical abstract is available asSupplementary information (Source: Pediatric Nephrology)
Source: Pediatric Nephrology - August 30, 2023 Category: Urology & Nephrology Source Type: research

Clinical profile of children with acute post-streptococcal glomerulonephritis
ConclusionGeneralized swelling, hypertension, and hematuria were most common presenting features. Persistent hypertension, impaired kidney function, and proteinuria persisted in a small proportion who had a significant clinical course and required kidney biopsy.Graphical abstractA higher resolution version of the Graphical abstract is available asSupplementary information (Source: Pediatric Nephrology)
Source: Pediatric Nephrology - August 30, 2023 Category: Urology & Nephrology Source Type: research

Differences in the urinary metabolome and proteome between wet and dry nights in children with monosymptomatic nocturnal enuresis and nocturnal polyuria
ConclusionsOxidative stress, which in the literature has been associated with nocturia and disturbances in sleep, might be increased during wet nights in children with MNE. We further found evidence of increased sympathetic activity. The mechanisms related to having wet nights in children with MNE seem complex, and both free water and solute handling appear to be important.Graphical abstractA higher resolution version of the Graphical abstract is available asSupplementary information (Source: Pediatric Nephrology)
Source: Pediatric Nephrology - August 30, 2023 Category: Urology & Nephrology Source Type: research