Magnetic Resonance Materials in Physics, Biology and Medicine This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

The role of MRI in prostate cancer: current and future directions
AbstractThere has been an increasing role of magnetic resonance imaging (MRI) in the management of prostate cancer. MRI already plays an essential role in the detection and staging, with the introduction of functional MRI sequences. Recent advancements in radiomics and artificial intelligence are being tested to potentially improve detection, assessment of aggressiveness, and provide usefulness as a prognostic marker. MRI can improve pretreatment risk stratification and therefore selection of and follow-up of patients for active surveillance. MRI can also assist in guiding targeted biopsy, treatment planning and follow-up ...
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - March 16, 2022 Category: Materials Science Source Type: research

Investigating acute changes in osteoarthritic cartilage by integrating biomechanics and statistical shape models of bone: data from the osteoarthritis initiative
DiscussionWalking and cycling caused distinct patterns of cartilage deformation, which depended on knee JRFs and bone morphology. For the first time, these results show that cartilage deformation is dependent on bone shapes and JRFs in vivo. (Source: Magnetic Resonance Materials in Physics, Biology and Medicine)
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - March 14, 2022 Category: Materials Science Source Type: research

Relative pressure estimation from 4D flow MRI using generalized Bernoulli equation in a phantom model of arterial stenosis
ConclusionGBE methods showed robust performance to additive image noise compared to other methods. Our findings indicate that GBE pressure estimation over pathlines attains the highest level of accuracy compared to GBE over streamlines, and the SBE and RBE methods. (Source: Magnetic Resonance Materials in Physics, Biology and Medicine)
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - February 17, 2022 Category: Materials Science Source Type: research

Pseudo-T2 mapping for normalization of T2-weighted prostate MRI
DiscussionAll AutoRef versions reduced variation in the multicenter data. AutoRefFH pseudo-T2s were closest to experimentally measured T2s. (Source: Magnetic Resonance Materials in Physics, Biology and Medicine)
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - February 12, 2022 Category: Materials Science Source Type: research

Hemodynamics in a three-dimensional printed aortic model: a comparison of four-dimensional phase-contrast magnetic resonance and image-based computational fluid dynamics
ConclusionsThis study compared the characteristics of PC-MRI and CFD through a phantom study that only included controllable experimental parameters. Based on these results, 4D PC-MRI and CFD are powerful tools for analyzing blood flow patterns in vivo. However, there is room for future developments to improve velocity measurement accuracy. (Source: Magnetic Resonance Materials in Physics, Biology and Medicine)
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - February 8, 2022 Category: Materials Science Source Type: research

The potential of advanced MR techniques for precision radiotherapy of glioblastoma
AbstractAs microscopic tumour infiltration of glioblastomas is not visible on conventional magnetic resonance (MR) imaging, an isotropic expansion of 1 –2 cm around the visible tumour is applied to define the clinical target volume for radiotherapy. An opportunity to visualize microscopic infiltration arises with advanced MR imaging. In this review, various advanced MR biomarkers are explored that could improve target volume delineation for radi otherapy of glioblastomas. Various physiological processes in glioblastomas can be visualized with different advanced MR techniques. Combining maps of oxygen metabolism (CMRO2),...
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - February 7, 2022 Category: Materials Science Source Type: research

Correction to: 3D APT and NOE CEST-MRI of healthy volunteers and patients with non-enhancing glioma at 3  T
(Source: Magnetic Resonance Materials in Physics, Biology and Medicine)
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - February 5, 2022 Category: Materials Science Source Type: research

Oxygen saturation-dependent effects on blood transverse relaxation at low fields
Conclusion\(\textit{T}_{2}\) changes in blood due to oxygenation were observed at fields as low as 0.1  T. These results suggest that low field NMR relaxometry devices around 0.3 T could be designed to detect changes in blood oxygenation. (Source: Magnetic Resonance Materials in Physics, Biology and Medicine)
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - February 2, 2022 Category: Materials Science Source Type: research

Micro- to macroscale magnetic resonance imaging of glioma
(Source: Magnetic Resonance Materials in Physics, Biology and Medicine)
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - February 2, 2022 Category: Materials Science Source Type: research

Biopsy-based optimization and calibration of a signal-intensity-ratio-based MRI method (1.5 Tesla) in a dextran-iron loaded mini-pig model, enabling estimation of very high liver iron concentrations
DiscussionThe wider measuring range is likely caused by lesser sensitivity of the SE sequence to iron, due to shorter TE, leading to later signal loss at high LIC, allowing evaluation of most severe hepatic iron overload. Validation in iron-loaded patients is necessary. (Source: Magnetic Resonance Materials in Physics, Biology and Medicine)
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - January 17, 2022 Category: Materials Science Source Type: research

What do we know about dynamic glucose-enhanced (DGE) MRI and how close is it to the clinics? Horizon 2020 GLINT consortium report
AbstractCancer is one of the most devastating diseases that the world is currently facing, accounting for 10  million deaths in 2020 (WHO). In the last two decades, advanced medical imaging has played an ever more important role in the early detection of the disease, as it increases the chances of survival and the potential for full recovery. To date, dynamic glucose-enhanced (DGE) MRI using glucose-based chemical exchange saturation transfer (glucoCEST) has demonstrated the sensitivity to detect bothd-glucose and glucose analogs, such as 3-oxy-methyl-d-glucose (3OMG) uptake in tumors. As one of the recent international e...
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - January 15, 2022 Category: Materials Science Source Type: research

Non-parametric deconvolution using B ézier curves for quantification of cerebral perfusion in dynamic susceptibility contrast MRI
In this study, the use of Bézier curves is proposed for obtaining physiologically reasonable residue functions in perfusion MRI.Materials and methodsCubic B ézier curves were employed, ensuringR(0)  = 1, bounded-input, bounded-output stability and a non-negative monotonically decreasing solution, resulting in 5 parameters to be optimized. Bézier deconvolution (BzD), implemented in a Bayesian framework, was tested by simulation under realistic conditions, including effects of arterial dela y and dispersion. BzD was also applied to DSC-MRI data from a healthy volunteer.ResultsB ézier deconvolution showed robustness t...
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - January 13, 2022 Category: Materials Science Source Type: research

Impact of white-matter mask selection on DTI histogram-based metrics as potential biomarkers in cerebral small vessel disease
ConclusionThe impact of the processing methodology, in particular the choice of white-matter mask, highlights the need for standardized MRI data-processing pipelines. (Source: Magnetic Resonance Materials in Physics, Biology and Medicine)
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - January 8, 2022 Category: Materials Science Source Type: research

Towards an integrated neonatal brain and cardiac examination capability at 7  T: electromagnetic field simulations and early phantom experiments using an 8-channel dipole array
ConclusionThe 8-channel dipole array design integrated for neonatal brain and cardiac MR was successfully demonstrated, in simulation with coverage of the baby and increased SAR efficiency levels compared to the birdcage. We conclude that the 8Tx-dipole array promises safe operating procedures for MR imaging of neonatal brain and heart at 7  T. (Source: Magnetic Resonance Materials in Physics, Biology and Medicine)
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - January 8, 2022 Category: Materials Science Source Type: research

3D APT and NOE CEST-MRI of healthy volunteers and patients with non-enhancing glioma at 3  T
ConclusionThis work showed that with a rapid CEST acquisition using aB1 saturation power of 1.5 µT and covering the whole tumor, analysis of both LD APT and MTRREX NOE allows for observing tumor heterogeneity, which will be beneficial in future studies using CEST-MRI to improve imaging diagnostics for non-enhancing glioma. (Source: Magnetic Resonance Materials in Physics, Biology and Medicine)
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - January 7, 2022 Category: Materials Science Source Type: research