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Is the optimal Tmax threshold identifying perfusion deficit volumes variable across MR perfusion software packages? A pilot study
ConclusionsThe optimal Tmax threshold for defining the ischemic penumbra appeared to be most accurate at  ≥ 6 s for package A and ≥ 10 s for package B. This implies that the widely recommended Tmax threshold ≥ 6 s may not be optimal for all available MRP software package. Future validation studies are required to define the optimal Tmax threshold to use for each package. (Source: Magnetic Resonance Materials in Physics, Biology and Medicine)
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - February 22, 2023 Category: Materials Science Source Type: research

Segmentation of the aorta in systolic phase from 4D flow MRI: multi-atlas vs. deep learning
ConclusionTo reduce biases in the calculation of aortic wall pressure, accurate segmentation is needed, particularly in regions with high blood flow velocities. Thus, the deep learning segmen-tation method should be preferred. (Source: Magnetic Resonance Materials in Physics, Biology and Medicine)
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - February 17, 2023 Category: Materials Science Source Type: research

Apparent diffusion coefficients of 31P metabolites in the human calf muscle at 7  T
ConclusionThe ADCs of four31P metabolites were successfully measured in the human calf muscle at 7  T, among which those of ATP, Pi and GPC were reported for the first time in humans. This study paves the way to investigate31P metabolite diffusion properties in health and disease on the clinical MR scanner. (Source: Magnetic Resonance Materials in Physics, Biology and Medicine)
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - February 8, 2023 Category: Materials Science Source Type: research

Extra-axonal contribution to double diffusion encoding-based pore size estimates in the corticospinal tract
ConclusionThe results suggest that the DDE-based size estimate may be considerably influenced by the extra-axonal compartment. However, the experimental results are also consistent with purely intra-axonal contributions in combination with a large fiber orientation dispersion. (Source: Magnetic Resonance Materials in Physics, Biology and Medicine)
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - February 6, 2023 Category: Materials Science Source Type: research

Magnetic Resonance Acoustic Radiation Force Imaging (MR-ARFI) for the monitoring of High Intensity Focused Ultrasound (HIFU) ablation in anisotropic tissue
DiscussionMR-ARFI allowed for monitoring of viscoelasticity changes around the HIFU focal spot even in anisotropic muscle tissue. (Source: Magnetic Resonance Materials in Physics, Biology and Medicine)
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - February 1, 2023 Category: Materials Science Source Type: research

Commissioning of the Iseult CEA 11.7  T whole-body MRI: current status, gradient–magnet interaction tests and first imaging experience
This article reviews its commissioning status, the gradient –magnet interaction test results and first imaging experience.Materials and methodsVibration, acoustics, power deposition in the He bath, and field monitoring measurements were carried out. Magnet safety system was tested against outer magnetic perturbations, and calibrated to define a safe operation of the gradient coil. First measurements using parallel transmission were also performed on an ex-vivo brain to mitigate the RF field inhomogeneity effect.ResultsAcoustics measurements show promising results with sound pressure levels slightly above the enforced lim...
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - January 30, 2023 Category: Materials Science Source Type: research

Estimation of intravoxel incoherent motion (IVIM) parameters in vertebral bone marrow: a comparative study of five algorithms
DiscussionThe comparison of the five algorithms indicates that the Bayesian algorithm provides the best estimation of VBM –IVIM parameters, in both numerical simulations and in vivo data. (Source: Magnetic Resonance Materials in Physics, Biology and Medicine)
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - January 30, 2023 Category: Materials Science Source Type: research

Rapid microscopic 3D-diffusion tensor imaging fiber-tracking of mouse brain in vivo by super resolution reconstruction: validation on MAP6-KO mouse model
DiscussionFirst performance of the SRR to generate rapid HSR 3D-DTI of mouse brains in vivo is demonstrated. The method is suitable in neurosciences for longitudinal studies to identify molecular and genetic abnormalities in mouse models that are of growing developments. (Source: Magnetic Resonance Materials in Physics, Biology and Medicine)
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - January 25, 2023 Category: Materials Science Source Type: research

Towards functional spin-echo BOLD line-scanning in humans at 7T
DiscussionThis low functional sensitivity needs to be addressed before SELINE can be applied for neuroscientific purposes. (Source: Magnetic Resonance Materials in Physics, Biology and Medicine)
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - January 10, 2023 Category: Materials Science Source Type: research

Assessment of MRF for simultaneous T1 and T2 quantification and water –fat separation in the liver at 0.55 T
ConclusionIt is feasible to measureT1 andT2 simultaneously in the liver using MRF on a 0.55  T system with lower performance gradients compared to state-of-the-art 1.5 T and 3 T systems within an acquisition time of 15 s. In addition, rosette MRF enables water–fat separation along withT1 andT2 quantification with no time penalty. (Source: Magnetic Resonance Materials in Physics, Biology and Medicine)
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - December 27, 2022 Category: Materials Science Source Type: research

Automatic segmentation of human supraclavicular adipose tissue using high-resolution T2-weighted magnetic resonance imaging
ConclusionThe present study demonstrates that the proposed automatic segmentation method using U-Net network is able to identify human sclavAT efficiently and accurately. (Source: Magnetic Resonance Materials in Physics, Biology and Medicine)
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - December 20, 2022 Category: Materials Science Source Type: research

Comparing magnetic resonance liver fat fraction measurements with histology in fibrosis: the difference between proton density fat fraction and tissue mass fat fraction
This study investigated these discrepancies and considered whether a tissue water content correction, as assessed by MRI relaxometry, could provide better agreement.Materials and methods110 patients were scanned in a 1.5  T Philips scanner and biopsies were obtained. Multiple echo MRS (30 × 30 ×  30 mm volume) was used to determine Proton Density Fat Fraction (PDFF). Biopsies were assessed by visual assessment for fibrosis and steatosis grading. Digital image analysis (DIA) was also used to quantify fat fraction within tissue samples. T1 relaxation times were then used to estimate tissue water content to correc...
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - December 20, 2022 Category: Materials Science Source Type: research

Comparison of conventional and higher-resolution reduced-FOV diffusion-weighted imaging of breast tissue
DiscussionAlthough ghost artifacts were observed for both acquisitions, they appeared to have a greater impact for rFOV-DWI. However, no differences in mean lesions ’ ADC values were found, and therefore this study suggests that rFOV can be used diagnostically for single-breast DWI imaging. (Source: Magnetic Resonance Materials in Physics, Biology and Medicine)
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - December 17, 2022 Category: Materials Science Source Type: research

Quantitative MRI of diffuse liver diseases: techniques and tissue-mimicking phantoms
In this study, we review the liver morphology associated with these diffuse diseases, discuss the quantitative MR techniques for assessing these liver pathologies, and comprehensively examine published liver phantom studies and discuss their benefits and limitations. (Source: Magnetic Resonance Materials in Physics, Biology and Medicine)
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - December 14, 2022 Category: Materials Science Source Type: research

Application value of simultaneous multislice readout-segmented echo-planar imaging for diffusion-weighted MRI in differentiation of rectal cancer grade
DiscussionSMS technology with an acceleration factor of 2 could be applied clinically to evaluate the pathological differentiation of rectal cancer grade. (Source: Magnetic Resonance Materials in Physics, Biology and Medicine)
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - December 10, 2022 Category: Materials Science Source Type: research