Automated reference tissue normalization of T2-weighted MR images of the prostate using object recognition
AbstractObjectivesTo develop and evaluate an automated method for prostate T2-weighted (T2W) image normalization using dual-reference (fat and muscle) tissue.Materials and methodsTransverse T2W images from the publicly available PROMISE12 (N = 80) and PROSTATEx (N = 202) challenge datasets, and an in-house collected dataset (N = 60) were used. Aggregate channel features object detectors were trained to detect reference fat and muscle tissue regions, which were processed and utilized to normalize the 3D images by linear scaling. Mean prostate pseudo T2 values after normalization wer...
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - July 31, 2020 Category: Materials Science Source Type: research

Diffusion-weighted imaging in the assessment of renal function in patients with diabetes mellitus type 2
AbstractObjectiveInvestigation of functional magnetic resonance (MR) imaging role in early diagnosis of diabetic nephropathy (DN) in patients with diabetes mellitus (DM) type 2, by quantification of the apparent diffusion coefficient (ADC) and fractional anisotropy (FA) values.Material and methods10 healthy volunteers and 91 DM type 2 patients were scanned using diffusion-weighted imaging (DWI) and diffusion tensor imaging (DTI) sequences. Patients were divided into four groups based on the estimated glomerular filtration value (eGFR). ADC and FA values, calculated in six regions of interest in each kidney (cortex and medu...
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - July 30, 2020 Category: Materials Science Source Type: research

In vitro real-time magnetic resonance imaging for quantification of thrombosis
AbstractObjectivesThrombosis is a leading cause of failure for cardiovascular devices. While computational simulations are a powerful tool to predict thrombosis and evaluate the risk for medical devices, limited experimental data are available to validate the simulations. The aim of the current study is to provide experimental data of a growing thrombus for device-induced thrombosis.Materials and methodsThrombosis within a backward-facing step (BFS), or sudden expansion was investigated, using bovine and human blood circulated through the BFS model for 30  min, with a constant inflow rate of 0.76 L/min. Real-time thre...
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - July 29, 2020 Category: Materials Science Source Type: research

Detection of early cartilage degeneration in the tibiotalar joint using 3 T gagCEST imaging: a feasibility study
AbstractObjectiveTo establish and optimize a stable 3 Tesla (T) glycosaminoglycan chemical exchange saturation transfer (gagCEST) imaging protocol for assessing the articular cartilage of the tibiotalar joint in healthy volunteers and patients after a sustained injury to the ankle.MethodsUsing Bloch –McConnell simulations, we optimized the sequence protocol for a 3 T MRI scanner for maximum gagCEST effect size within a clinically feasible time frame of less than 07:30 min. This protocol was then used to analyze the gagCEST effect of the articular cartilage of the tibiotalar joint of 17 healt hy volunteers and fi...
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - July 28, 2020 Category: Materials Science Source Type: research

Disrupted white matter connectivity and organization of brain structural connectomes in tuberous sclerosis complex patients with neuropsychiatric disorders using diffusion tensor imaging
AbstractObjectiveTuberous sclerosis complex (TSC) is a genetic neurocutaneous syndrome with variable and unpredictable neurological comorbidity that includes epilepsy, intellectual disability (ID), autism spectrum disorder, and neurobehavioral abnormalities. The degree of white matter involvement is believed to be associated with the severity of neurological impairment. The goal of the present study was to evaluate diffusion characteristics of tubers, white matter lesions, and brain structural network alterations in TSC patients using diffusion tensor imaging (DTI), graph theoretical analysis (GTA), and network-based stati...
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - July 26, 2020 Category: Materials Science Source Type: research

Interactive tool to create adjustable anatomical atlases for mouse brain imaging
AbstractObjectiveBrain atlases are important research tools enabling researchers to focus their investigations on specific anatomically defined brain regions and are used in many MRI applications, e.g. in fMRI, morphometry, whole brain spectroscopy, et cetera. Despite their extensive use and numerous versions they usually consist of predefined rigid brain regions with a given level of detail often degrading them to a non-ideal tool in special research topics.ResultTo overcome this intrinsic weakness we present a graphical user interface application which allows researchers to easily create mouse brain atlases with an adjus...
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - July 21, 2020 Category: Materials Science Source Type: research

Altered spontaneous brain activity in essential tremor with and without resting tremor: a resting-state fMRI study
This study aims to use resting-state functional magnetic resonance imaging (rs-fMRI) to explore the alterations of brain activity between the drug-na ïve patients of rET and ETwr.MethodsWe recruited 19 patients with rET, 31 patients with ETwr and 25 healthy controls (HCs) to undergo a 3.0-T rs-fMRI examination. The differences of regional brain spontaneous activity between the rET, ETwr and HCs, as well as between total ET (rET  + ETwr) and HCs were measured by amplitude of low-frequency fluctuation (ALFF) and fractional ALFF (fALFF). The relationships between the altered brain measurements and the clini...
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - July 13, 2020 Category: Materials Science Source Type: research

Combine contrast-enhanced 3D T2-weighted short inversion time inversion recovery MR neurography with MR angiography at 1.5  T in the assessment of brachial plexopathy
AbstractPurposeTo explore the benefits of using a single injection of contrast agent at a 1.5  T system to perform both contrast-enhanced MR angiography (MRA) and 3D-T2-STIR MR neurography (MRN) to assess of brachial plexopathy.MethodsIn this prospective study, 27 patients with suspected brachial plexopathy, received an imaging procedure composed sequentially of non-enhanced 3D-T2-STIR, CE-MRA, and contrast-enhanced 3D-T2-STIR, using a 1.5  T MR scanner. Signal intensities and contrast ratios were compared with and without contrast agent. The non-enhanced and contrast-enhanced 3D-T2-STIR images were mixed for two...
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - July 13, 2020 Category: Materials Science Source Type: research

Characterization of hardware-related spatial distortions for IR-PETRA pulse sequence using a brain specific phantom
DiscussionThe spatial accuracy of MR images, besides being impacted by hardware performance, scanner capabilities, and imaging parameters, is mainly affected by its imaging strategy and data acquisition scheme. In 3.0  T, even without applying vendor correction algorithms, spatial accuracy of IR-PETRA image is sufficient for generating pseudo-CTs. In 1.5 T, distortion-correction is required to provide this accuracy. (Source: Magnetic Resonance Materials in Physics, Biology and Medicine)
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - July 6, 2020 Category: Materials Science Source Type: research

Application of a stretched-exponential model for morphometric analysis of accelerated diffusion-weighted 129Xe MRI of the rat lung
AbstractObjectiveDiffusion-weighted, hyperpolarized129Xe MRI is useful for the characterization of microstructural changes in the lung. A stretched exponential model was proposed for morphometric extraction of the mean chord length (Lm) from diffusion-weighted data. The stretched exponential model enables accelerated mapping ofLm in a single-breathhold using compressed sensing. Our purpose was to compareLm maps obtained from stretched-exponential model analysis of accelerated versus unaccelerated diffusion-weighted129Xe MRI data obtained from healthy/injured rat lungs.Material and methodsLm maps were generated using a stre...
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - July 6, 2020 Category: Materials Science Source Type: research

Comparison of models of diffusion in Wilms ’ tumours and normal contralateral renal tissue
This study aimed to compare the suitability of four diffusion models (mono exponential, IVIM [Intravoxel Incoherent Motion], stretched exponential, and kurtosis) in Wilms’ tumours and the unaffected contralateral kidneys.Materials and methodsDWI data were retrospectively reviewed(110 Wilms ’ tumours and 75 normal kidney datasets). The goodness of fit for each model was measured voxel-wise using Akaike Information Criteria (AIC). Mean AIC was calculated for each tumour volume (or contralateral normal kidney tissue). One-way ANOVAs with Greenhouse–Geisser correction and post hoc tes ts using the Bonferroni ...
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - July 2, 2020 Category: Materials Science Source Type: research

Parallel implementation of L  +  S signal recovery in dynamic MRI
AbstractDynamic MRI is useful to diagnose different diseases, e.g. cardiac ailments, by monitoring the structure and function of the heart and blood flow through the valves. Faster data acquisition is highly desirable in dynamic MRI, but this may lead to aliasing artifacts due to under-sampling. Advanced image reconstruction algorithms are required to obtain aliasing-free MR images from the acquired under-sampled data. One major limitation of using the advanced reconstruction algorithms is their computationally expensive and time-consuming nature, which make them infeasible for clinical use, especially for applications lik...
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - June 29, 2020 Category: Materials Science Source Type: research

Accelerating the co-simulation method for the design of transmit array coils for MRI
ConclusionA fast and accurate method for tuning and decoupling of a TxArray coil can be achieved using its equivalent circuit model combined with the co-simulation method. (Source: Magnetic Resonance Materials in Physics, Biology and Medicine)
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - June 27, 2020 Category: Materials Science Source Type: research

Magnetic resonance markers of bilateral neuronal metabolic dysfunction in patients with unilateral internal carotid artery occlusion
DiscussionPatients with unilateral ICA occlusion have reduced NAA/Cho ratio in the white matter of both hemispheres and have bilateral atrophy of hippocampus. The alteration of hemodynamics alone cannot explain these changes. (Source: Magnetic Resonance Materials in Physics, Biology and Medicine)
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - June 27, 2020 Category: Materials Science Source Type: research

Generalization of three-dimensional golden-angle radial acquisition to reduce eddy current artifacts in bSSFP CMR imaging
ConclusionReducing the angular step in cardio-respiratory-binned golden-angle imaging shows potential for overcoming eddy current-induced image artifacts associated with 3D golden-angle radial imaging. (Source: Magnetic Resonance Materials in Physics, Biology and Medicine)
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - June 26, 2020 Category: Materials Science Source Type: research

Influence of injection rate in determining the development of artifacts during the acquisition of dynamic arterial phase in Gd-EOB-DTPA MRI studies
AbstractObjectiveTo assess whether different Gd-EOB-DTPA injection rates could influence the development of artifacts during the arterial phase of liver MRI studies.Materials and methodsAll Gd-EOB-DTPA liver MRI studies performed for different clinical indications at a single tertiary referral center were retrospectively evaluated. Each examination was acquired on a 1.5  T scanner with T1 In- and Out-of-Phase, T2 with and without fat-saturation, DWI, and 3D-T1 fat-sat dynamic sequences. Patients were divided into two groups according to the injection rate (1 ml/s and 1.5 ml/s). A single radiologist recorded ...
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - June 19, 2020 Category: Materials Science Source Type: research

Correction to: Phase-contrast magnetic resonance imaging to assess renal perfusion: a systematic review and statement paper
The article Phase ‑contrast magnetic resonance imaging to assess renal perfusion: a systematic review and statement paper, written by Giulia Villa, Steffen Ringgaard, Ingo Hermann, Rebecca Noble, Paolo Brambilla, Dinah S. Khatir, Frank G. Zöllner, Susan T. Francis, Nicholas M. Selby, Andrea Remuzzi and Anna Caroli , was originally published electronically on the publisher’s internet portal on 17 August 2019 without open access (Source: Magnetic Resonance Materials in Physics, Biology and Medicine)
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - June 11, 2020 Category: Materials Science Source Type: research

Correction to: Image registration in dynamic renal MRI —current status and prospects
The article Image registration in dynamic renal MRI —current status and prospects, written by Frank G. Zöllner, Amira Šerifović‑Trbalić, Gordian Kabelitz, Marek Kociński, Andrzej Materka and Peter Rogelj, was originally published electronically on the publisher’s internet portal on 9 October 2019 without open access.With the author(s)’ d ecision to opt for Open Choice the copyright of the article changed on 24 April 2020 to © (Source: Magnetic Resonance Materials in Physics, Biology and Medicine)
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - June 11, 2020 Category: Materials Science Source Type: research

Sodium MRI of human articular cartilage of the wrist: a feasibility study on a clinical 3T MRI scanner
ConclusionWe successfully determined sodium relaxation times and concentrations of the human wrist on a 3T MRI scanner. (Source: Magnetic Resonance Materials in Physics, Biology and Medicine)
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - June 4, 2020 Category: Materials Science Source Type: research

SWI and phase imaging reveal intracranial calcifications in the P301L mouse model of human tauopathy
DiscussionSWI and phase imaging sensitively detected intracranial calcifications in the P301L mouse model of human tauopathy. (Source: Magnetic Resonance Materials in Physics, Biology and Medicine)
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - May 28, 2020 Category: Materials Science Source Type: research

Assessment of brain volumes obtained from MP-RAGE and MP2RAGE images, quantified using different segmentation methods
ConclusionThe results obtained advise caution when comparing brain volumes obtained by different sequences and software packages. Of note, for most brain volume measures, the MP2RAGE and MorphoBox coefficients of variation were similar to those obtained with MP-RAGE, SIENA/X or SPM, accepted tools for clinical research. (Source: Magnetic Resonance Materials in Physics, Biology and Medicine)
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - May 28, 2020 Category: Materials Science Source Type: research

Effectiveness of fat suppression using a water-selective binomial-pulse excitation in chemical exchange saturation transfer (CEST) magnetic resonance imaging
ConclusionIn WE-4-based CEST magnetic resonance imaging,B0 inhomogeneity is the limiting factor for fat suppression. The CEST sites at 1.0, 2.0  ppm and 3.5 ppm unavoidably suffer from lipid artifacts. However, when the∆B0 is confined to a limited range, these CEST sites are only affected by small lipid artifacts, which may be ignorable in some cases of clinical applications. (Source: Magnetic Resonance Materials in Physics, Biology and Medicine)
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - May 27, 2020 Category: Materials Science Source Type: research

Modeling radio-frequency energy-induced heating due to the presence of transcranial electric stimulation setup at 3T
ConclusionSimulation results predicted that the electrode and gel geometries, skin electrical conductivity, and position of the temperature sensors have a significant impact on the estimated temperature rise. Therefore, these factors must be considered for reliable assessment of ΔT in subjects undergoing an MRI examination in the presence of a tES setup. (Source: Magnetic Resonance Materials in Physics, Biology and Medicine)
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - May 27, 2020 Category: Materials Science Source Type: research

Layer-specific analysis of femorotibial cartilage t2 relaxation time based on registration of segmented double echo steady state (dess) to multi-echo-spin-echo (mese) images
AbstractObjectiveTo develop and validate a 3D registration approach by which double echo steady state (DESS) MR images with cartilage thickness segmentations are used to extract the cartilage transverse relaxation time (T2) from multi-echo-spin-echo (MESE) MR images, without direct segmentations for MESE.Materials and methodsManual DESS segmentations of 89 healthy reference knees (healthy) and 60 knees with early radiographic osteoarthritis (early ROA) from the Osteoarthritis Initiative were registered to corresponding MESE images that had independent direct T2 segmentations. For validation purposes, (a) regression analysi...
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - May 26, 2020 Category: Materials Science Source Type: research

Single breath-hold saturation recovery 3D cardiac T1 mapping via compressed SENSE at 3T
Conclusion3D SACORA acquires 3D T1 maps in 15 heart beats (heart rate, 60 bpm) at 3T. In addition to its short acquisition time, the sequence achieves good T1 estimation precision and accuracy. (Source: Magnetic Resonance Materials in Physics, Biology and Medicine)
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - May 14, 2020 Category: Materials Science Source Type: research

Diffusion kurtosis imaging in liver: a preliminary reproducibility study in healthy volunteers
AbstractObjectivesTo systematically test the reproducibility of DKI technique in normal liver and report a complete set of DKI measurement data.Materials and methodsThirty-two healthy volunteers were examined with liver DKI twice on the GE 3.0  T MRI scanner and reviewed by three professional experts. DKI-derived parameters fractional anisotropy of kurtosis (FAk), mean diffusivity (Md), axial diffusivity (Da), radial diffusivity (Dr), mean kurtosis (Mk), axial kurtosis (Ka), and radial kurtosis (Kr) in eight segments divided by Couinaud octagonal method were collected. Inter-class correlation coefficient (ICC) was use...
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - May 6, 2020 Category: Materials Science Source Type: research

Examining relaxivities in suspensions of nanodiamonds grafted by magnetic entities: comparison of two approaches
AbstractObjectivesDetonation nanodiamonds (DND) with Gd3+ ions directly grafted to the DND surface have recently demonstrated enhanced relaxivity for protons in aqueous suspensions. Herewith, the relaxivity measurements were done on a series of suspensions with the gadolinium content varied by changing number of Gd3+ ions grafted per each DND particle whereas the DND content in each suspension was kept the same. Such an approach to vary the contrast agent content differs from that commonly used in the relaxivity measurements. In the common approach, contrast agents are directly dissolved/suspended in media. Aiming to test ...
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - April 28, 2020 Category: Materials Science Source Type: research

MRI-based static and functional assessment of complex hip deformities in comparison with CT: a validation study
ConclusionFinally, it was concluded that MRI-based assessment of hip morphology and virtual ROM analysis is feasible and can be performed with good intermethod agreement in comparison to the gold standard (CT). Therefore, MRI appears to be substantially equivalent to CT for use in virtual ROM analysis and so may reasonably be used in place of CT for this purpose. (Source: Magnetic Resonance Materials in Physics, Biology and Medicine)
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - April 22, 2020 Category: Materials Science Source Type: research

An MRI-compatible varus –valgus loading device for whole-knee joint functionality assessment based on compartmental compression: a proof-of-concept study
This study aimed to design and validate an MRI-compatible pressure-controlled varus –valgus loading device that applies loading along the joint line.MethodsFollowing the device ’s thorough validation, we demonstrated proof of concept by subjecting a structurally intact human cadaveric knee joint to serial imaging in unloaded and loaded configurations, i.e. to varus and valgus loading at 7.5 kPa (= 73.5 N), 15 kPa (= 147.1 N), and 22.5 kPa (= 220.6 N). Followi ng clinical standard (PDw fs) and high-resolution 3D water-selective cartilage (WATSc) sequences, we pe...
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - April 20, 2020 Category: Materials Science Source Type: research

Quantitative measurement of atheroma burden: reproducibility in serial studies of atherosclerotic femoral arteries
ConclusionDASH MRI is useful for quantifying atherosclerotic vessel area and volume of femoral arteries with low variability among serial repeated scans and between observers. (Source: Magnetic Resonance Materials in Physics, Biology and Medicine)
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - April 16, 2020 Category: Materials Science Source Type: research

Acceleration of 2D-MR fingerprinting by reducing the number of echoes with increased in-plane resolution: a volunteer study
AbstractObjectiveTo compare the absolute values and repeatability of magnetic resonance fingerprinting (MRF) with 3000 and 1500 echoes/slice acquired in 41  s and 20 s (MRF3k and MRF1.5k, respectively).Materials and methodsMRF3k and MRF1.5k scans based on fast imaging with steady precession (FISP) were conducted using a 3  T scanner. Inter-scan agreement and intra-scan repeatability were investigated in 41 and 28 subjects, respectively. Region-of-interest (ROI) analysis was conducted on T1 values of MRF3k by two raters, and their agreement was evaluated using intraclass correlation coefficients (ICCs). Betwe...
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - April 4, 2020 Category: Materials Science Source Type: research

An in vivo proton magnetic resonance spectroscopy study with optimized echo-time technique for concurrent quantification and T2 measurement targeting glutamate in the rat brain
DiscussionThe results revealed that the quantification reliability of the OpQT2-Glu was comparable to that of the single short-TE MRS and its estimation reliability for the T2 relaxation time of glutamate was enhanced compared to the multiple TE MRS for T2 measurement. Despite certain limitations, the quantification and T2 estimation of glutamate can be concurrently performed within an acceptable scan time via high-field in vivo1H MRS with the OpQT2-Glu. (Source: Magnetic Resonance Materials in Physics, Biology and Medicine)
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - April 3, 2020 Category: Materials Science Source Type: research

Non-contrast coronary magnetic resonance angiography: current frontiers and future horizons
AbstractCoronary magnetic resonance angiography (coronary MRA) is advantageous in its ability to assess coronary artery morphology and function without ionizing radiation or contrast media. However, technical limitations including reduced spatial resolution, long acquisition times, and low signal-to-noise ratios prevent it from clinical routine utilization. Nonetheless, each of these limitations can be specifically addressed by a combination of novel technologies including super-resolution imaging, compressed sensing, and deep-learning reconstruction. In this paper, we first review the current clinical use and motivations ...
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - April 2, 2020 Category: Materials Science Source Type: research

Use of multiparametric MRI to characterize uterine fibroid tissue types
AbstractBackgroundAlthough the biological characteristics of uterine fibroids (UF) have implications for therapy choice and effectiveness, there is limited MRI data about these characteristics. Currently, the Funaki classification and Scaled Signal Intensity (SSI) are used to predict treatment outcome but both screening-tools appear to be suboptimal. Therefore, multiparametric and quantitative MRI was studied to evaluate various biological characteristics of UF.Methods87 patients with UF underwent an MRI-examination. Differences between UF tissues and myometrium were investigated using T2-mapping, Apparent Diffusion Coeffi...
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - March 26, 2020 Category: Materials Science Source Type: research

Automated multi-atlas segmentation of gluteus maximus from Dixon and T1-weighted magnetic resonance images
ConclusionThe method allows an accurate fully automated segmentation of gluteus maximus for Dixon and T1-weighted images and provides a relatively accurate volume measurement in shorter times (~  20 min) than the current gold-standard manual segmentations (2 h). Visual inspection of the segmentation would be required when higher accuracy is needed. (Source: Magnetic Resonance Materials in Physics, Biology and Medicine)
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - March 9, 2020 Category: Materials Science Source Type: research

Analysis of three-chamber view conventional and tagged cine MRI in patients with suspected hypertrophic cardiomyopathy
AbstractObjectivesTo investigate the potential value of adding a tagged three-chamber (3Ch) cine to clinical hypertrophic cardiomyopathy (HCM) magnetic resonance imaging (MRI) protocols, including to help distinguish HCM patients with regionally impaired cardiac function.MethodsForty-eight HCM patients, five patients with “septal knuckle” (SK), and 20 healthy volunteers underwent MRI at 1.5T; a tagged 3Ch cine was added to the protocol. Regional strain, myocardial wall thickness, and mitral valve leaflet lengths were measured in the 3Ch view.ResultsIn HCM, we found a reduced tangential strain with decreased dia...
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - March 9, 2020 Category: Materials Science Source Type: research

Treatment margins in radiotherapy for liver tumors visualized as T2*-hypointense areas on SPIO-enhanced MRI at 9.4  T
AbstractObjectiveTo investigate whether a SPIO-labeling technique could enable MR visualization of the treatment margin after X-irradiation at a single dose of 30  Gy.Materials and methodsFifteen rats bearing N1-S1 hepatoma in either the left (group 1) or right (group 2) liver lobe were examined. Four hours after systemic SPIO administration, the left lobe was selectively irradiated at 30  Gy. Liver T2* maps were acquired 7 days later using a 9.4 T scanner. The livers were excised and examined histologically.ResultsThe irradiated area showed T2*-weighted hypointensity with significantly shorter T2* valu...
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - March 4, 2020 Category: Materials Science Source Type: research

Investigation of phase-contrast magnetic resonance imaging underestimation of turbulent flow through the aortic valve phantom: experimental and computational study using lattice Boltzmann method
DiscussionFlow measured by PC-MRI is affected by noise and turbulence. LBM can simulate turbulent flow efficiently and accurately, it has therefore the potential to improve clinical interpretation of PC-MRI. (Source: Magnetic Resonance Materials in Physics, Biology and Medicine)
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - February 27, 2020 Category: Materials Science Source Type: research

Dynamic contrast-enhanced QSM for perfusion imaging: a systematic comparison of Δ R 2*- and QSM-based contrast agent concentration time curves in blood and tissue
DiscussionInterestingly, arterial concentration time curves based on ΔR2* versus QSM data, for a standard DSC-MRI experiment, were generally very similar in shape, and the relaxivity obtained in voxels representing blood was similar to tissue relaxivity obtained in previous studies. (Source: Magnetic Resonance Materials in Physics, Biology and Medicine)
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - February 20, 2020 Category: Materials Science Source Type: research

Contrast-free high-resolution 3D magnetization transfer imaging for simultaneous myocardial scar and cardiac vein visualization
DiscussionMTR and LGE showed agreement in infarct detection and localization in a swine model. Free-breathing 3D MTR maps are feasible in humans but high spatial variability was observed. Further clinical studies are warranted. (Source: Magnetic Resonance Materials in Physics, Biology and Medicine)
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - February 20, 2020 Category: Materials Science Source Type: research

Correction to: Development of a new phantom simulating extracellular space of tumor cell growth and cell edema for diffusion-weighted magnetic resonance imaging
The original version of this article unfortunately contained a mistake. Second column of “Cell edema” should read as. (Source: Magnetic Resonance Materials in Physics, Biology and Medicine)
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - February 14, 2020 Category: Materials Science Source Type: research

Correction to: Accelerated quantification of tissue sodium concentration in skeletal muscle tissue: quantitative capability of dictionary learning compressed sensing
The original version of this article unfortunately contained a mistake. Title was incorrect. (Source: Magnetic Resonance Materials in Physics, Biology and Medicine)
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - February 12, 2020 Category: Materials Science Source Type: research

T2 mapping of the distal sciatic nerve in healthy subjects and patients suffering from lumbar disc herniation with nerve compression
DiscussionA T2-prepared TSE sequence enables precise determination of T2 values of the distal sciatic nerve in agreement with MRS. A MESE sequence tends to overestimate nerve T2 compared to T2 from MRS due to the influence of residual fat on T2 quantification. Our approach may enable to quantitatively assess direct nerve affection related to nerve compression. (Source: Magnetic Resonance Materials in Physics, Biology and Medicine)
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - February 11, 2020 Category: Materials Science Source Type: research

Impact of ascending aorta replacement by graft on elastic properties of descending thoracic aorta evaluated by cardiac magnetic resonance imaging
AbstractObjectiveThe aim of our study was to evaluate the impact of aortic root replacement by graft on the elastic properties of the descending thoracic aorta using cardiac magnetic resonance imaging (MRI) and automatic post-processing.Materials and methodsNineteen patients were operated for an aortic root aneurysm. Cardiac MRI was performed before and after surgery to measure aortic compliance. Images were acquired on a 1.5  T MRI with a conventional aortic MRI protocol plus one additional kinetic sequence orientated perpendicularly to the aorta at the level of pulmonary trunk. The contours of the ascending and desc...
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - January 31, 2020 Category: Materials Science Source Type: research

Correction to: Consensus-based technical recommendations for clinical translation of renal diffusion-weighted MRI
The article Consensus-based technical recommendations for clinical translation of renal diffusion-weighted MRI (Source: Magnetic Resonance Materials in Physics, Biology and Medicine)
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - January 28, 2020 Category: Materials Science Source Type: research

Low-level fat fraction quantification at 3  T: comparative study of different tools for water–fat reconstruction and MR spectroscopy
AbstractObjectivesChemical Shift Encoded Magnetic Resonance Imaging (CSE-MRI)-based quantification of low-level (
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - January 24, 2020 Category: Materials Science Source Type: research

Sensitivity and uniformity improvement of phased array MR images using inductive coupling and RF detuning circuits
ConclusionThe designed secondary resonator having detuning circuits improved sensitivity and uniformity of mouse MR images acquired using the four-channel phased array. (Source: Magnetic Resonance Materials in Physics, Biology and Medicine)
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - January 24, 2020 Category: Materials Science Source Type: research

Accelerated quantification of tissue sodium concentration in skeletal muscle tissue: quantitative capability of dictionary learning compressed sensing
DiscussionThe optimized 3D-DLCS reconstruction enables accelerated TSC measurements with high quantification accuracy. (Source: Magnetic Resonance Materials in Physics, Biology and Medicine)
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - January 16, 2020 Category: Materials Science Source Type: research

A 12-channel flexible receiver coil for accelerated tongue imaging
AbstractObjectiveMRI of the tongue requires acceleration to minimise motion artefacts and to facilitate real-time imaging of swallowing. To accelerate tongue MRI, we designed a dedicated flexible receiver coil.Materials and methodsWe designed a flexible 12-channel receiver coil for tongue MRI at 3T and compared it to a conventional head-and-neck coil regarding SNR and g-factor. Furthermore, two accelerated imaging techniques were evaluated using both coils: multiband (MB) diffusion-tensor imaging (DTI) and real-time MRI of swallowing.ResultsThe flexible coil had significantly higher SNR in the anterior (2.1 times higher,P ...
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - January 16, 2020 Category: Materials Science Source Type: research

MR imaging of pulmonary lung nodules during one lung flooding: first morphological evaluation using an ex vivo human lung model
ConclusionSuperior conditions with new features of lung MRI were found during lung flooding with an unrestricted visualization of malignant nodules and clear demarcation of intra-pulmonary structures. This could lead to new applications of MR-based pulmonary interventions such as laser or focused ultrasound-based thermal ablations. (Source: Magnetic Resonance Materials in Physics, Biology and Medicine)
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - January 16, 2020 Category: Materials Science Source Type: research