Magnetic Resonance Materials in Physics, Biology and Medicine 
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This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.An empirical investigation of the benefit of increasing the temporal resolution of task-evoked fMRI data with multi-band imaging
ConclusionRather than universally increasing the temporal sampling rate in cognitive fMRI experiments, these results advocate the performance of a pilot study for the specific ROIs of interest to identify the appropriate temporal sampling rate for the acquisition and the correspondingly suitable HRF for the analysis of the data. (Source: Magnetic Resonance Materials in Physics, Biology and Medicine)
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - March 25, 2021 Category: Materials Science Source Type: research
A simple apparatus for safety assessment of magnetically induced torque on active implantable medical devices (AIMDs) under 1.5 T and 3.0 T MRI
DiscussionThe apparatus developed in this study was verified to be feasible for measuring magnetically induced torques, with tests on four types of AIMDs under 1.5 T and 3.0 T MRI environments. Although the designed structure is simple, the apparatus was shown to measure torque values of AIMDs under MRI accurately. (Source: Magnetic Resonance Materials in Physics, Biology and Medicine)
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - March 25, 2021 Category: Materials Science Source Type: research
Upper brainstem GABA levels in Parkinson ’s disease
ConclusionThe lower GABA + levels in the upper brainstem of the PD patients suggest that a GABAergic deficit in the brainstem may contribute to the pathology in PD. (Source: Magnetic Resonance Materials in Physics, Biology and Medicine)
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - March 20, 2021 Category: Materials Science Source Type: research
Voxel-based mapping of five MR biomarkers in the wrist bone marrow
DiscussionThe protocol and quantification tool proposed in this study provide high-resolution voxel-by-voxel 3D maps of five biomarkers in the wrist in less than 4 min of acquisition. (Source: Magnetic Resonance Materials in Physics, Biology and Medicine)
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - March 12, 2021 Category: Materials Science Source Type: research
Multiple b -values improve discrimination of cortical gray matter regions using diffusion MRI: an experimental validation with a data-driven approach
ConclusionAcquisitions with varyingb-values are more suitable for discriminating cortical areas. (Source: Magnetic Resonance Materials in Physics, Biology and Medicine)
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - March 12, 2021 Category: Materials Science Source Type: research
Multiparametric MRI-based machine learning models for preoperatively predicting rectal adenoma with canceration
ConclusionsMultiparametric MRI-based machine learning models have the potential to predict rectal adenoma with canceration. Compared with ModelT2 and ModelDWI, Modelcombined showed the best performance. Moreover, both LR and SVM have equal excellent performance for model construction. (Source: Magnetic Resonance Materials in Physics, Biology and Medicine)
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - March 1, 2021 Category: Materials Science Source Type: research
3D MRI of explanted sheep hearts with submillimeter isotropic spatial resolution: comparison between diffusion tensor and structure tensor imaging
This study demonstrated the feasibility of high-resolution MRI for studying the myocyte and myolaminar architecture of sheep hearts. We presented the results of STI on three whole sheep ex vivo hearts and demonstrated a good correspondence between DTI and STI. (Source: Magnetic Resonance Materials in Physics, Biology and Medicine)
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - February 27, 2021 Category: Materials Science Source Type: research
EGFR-specific single-chain variable fragment antibody-conjugated Fe 3 O 4 /Au nanoparticles as an active MRI contrast agent for NSCLC
AbstractOverexpression of epidermal growth factor receptor (EGFR) is closely associated with a poor prognosis in non-small cell lung cancer (NSCLC), thus making it a promising biomarker for NSCLC diagnosis. Here, we conjugated a single-chain antibody (scFv) targeting EGFR with Fe3O4/Au nanoparticles to form an EGFR-specific molecular MRI bioprobe (scFv@Fe3O4/Au) to better detect EGFR-positive NSCLC tumors in vivo. In vitro, we demonstrated that the EGFR-specific scFv could specifically deliver Fe3O4/Au to EGFR-positive NSCLC cells. In vivo experiments showed that the accumulation of scFv@Fe3O4/Au in tumor tissue was detect...
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - February 24, 2021 Category: Materials Science Source Type: research
Mapping tumour heterogeneity with pulsed 3D CEST MRI in non-enhancing glioma at 3 T
ConclusionThis works illustrates the need for whole tumour coverage to investigate heterogeneity in increased APT-weighted CEST signal in non-enhancing glioma. Future work should investigate whether targeting hyperintense LDamide regions for biopsies improves diagnosis of non-enhancing glioma. (Source: Magnetic Resonance Materials in Physics, Biology and Medicine)
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - February 19, 2021 Category: Materials Science Source Type: research
3T MEGA-PRESS study of N -acetyl aspartyl glutamate and N -acetyl aspartate in activated visual cortex
ConclusionThe MEGA-PRESS pulse sequence together with the spectral preprocessing techniques allowed to demonstrate that the concentrations of NAAG and NAA in the visual cortex remain constant during continuous visual stimulation within the margin of error. An increase in the lactate signal intensity signifies the activation of the anaerobic glycolysis in activated visual cortex. (Source: Magnetic Resonance Materials in Physics, Biology and Medicine)
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - February 16, 2021 Category: Materials Science Source Type: research
Editorial commentary for the special issue: technological developments in hyperpolarized 13 C imaging —toward a deeper understanding of tumor metabolism in vivo
(Source: Magnetic Resonance Materials in Physics, Biology and Medicine)
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - February 13, 2021 Category: Materials Science Source Type: research
A combined computational and experimental approach to assess the transfer function of real pacemaker leads for MR radiofrequency-induced heating
ConclusionFor the three PM lead tested, the error in the SAR estimation is within the uncertainty level of SAR measurements ( ± 2 dB). Additionally, the estimation of the TF using the reciprocity principle is influenced by the particular lead trajectory adopted, even if the consequent variability in the SAR estimation is still close to the uncertainty level of SAR measurements. (Source: Magnetic Resonance Materials in Physics, Biology and Medicine)
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - February 8, 2021 Category: Materials Science Source Type: research
Hydrogenative-PHIP polarized metabolites for biological studies
AbstractParaHydrogen induced polarization (PHIP) is an efficient and cost-effective hyperpolarization method, but its application to biological investigations has been hampered, so far, due to chemical challenges. PHIP is obtained by means of the addition of hydrogen, enriched in the para-spin isomer, to an unsaturated substrate. Both hydrogen atoms must be transferred to the same substrate, in a pairwise manner, by a suitable hydrogenation catalyst; therefore, a de-hydrogenated precursor of the target molecule is necessary. This has strongly limited the number of parahydrogen polarized substrates. The non-hydrogenative ap...
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - February 2, 2021 Category: Materials Science Source Type: research
Di-chromatic interpolation of magnetic resonance metabolic images
AbstractObjectiveMagnetic resonance imaging with hyperpolarized contrast agents can provide unprecedented in vivo measurements of metabolism, but yields images that are lower resolution than that achieved with proton anatomical imaging. In order to spatially localize the metabolic activity, the metabolic image must be interpolated to the size of the proton image. The most common methods for choosing the unknown values rely exclusively on values of the original uninterpolated image.MethodsIn this work, we present an alternative method that uses the higher-resolution proton image to provide additional spatial structure. The ...
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - January 27, 2021 Category: Materials Science Source Type: research
Effect of MRI acquisition acceleration via compressed sensing and parallel imaging on brain volumetry
ConclusionCS-acceleration has a systematic biasing effect on volumetric brain measurements. (Source: Magnetic Resonance Materials in Physics, Biology and Medicine)
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - January 27, 2021 Category: Materials Science Source Type: research
