3D magnetic resonance fingerprinting on a low-field 50  mT point-of-care system prototype: evaluation of muscle and lipid relaxation time mapping and comparison with standard techniques
DiscussionIt is possible to measure volumetric relaxation times with MRF at 2.5  × 2.5 × 3.0 mm3 resolution in a 13  min scan time on a 50 mT permanent magnet system. The measured MRF relaxation times are longer compared to those measured with reference techniques, especially forT2. This discrepancy can potentially be addressed by hardware, reconstruction and sequence design, but long-term reproducibility needs to be further improved. (Source: Magnetic Resonance Materials in Physics, Biology and Medicine)
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - May 18, 2023 Category: Materials Science Source Type: research

Impact of compressed sensing (CS) acceleration of two-dimensional (2D) flow sequences in clinical paediatric cardiovascular magnetic resonance (CMR)
ConclusionSBOF reduces breath-hold duration to 56% of COF. RV flow by SBOF was biased compared to COF. The variation (95% CI) between COF and SBOF was similar to the COF intrasession test –retest 95% CI. (Source: Magnetic Resonance Materials in Physics, Biology and Medicine)
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - May 18, 2023 Category: Materials Science Source Type: research

Tackling SNR at low-field: a review of hardware approaches for point-of-care systems
DiscussionThere are many different magnet and RF coil designs in the literature, and to enable meaningful comparisons and optimizations to be performed it would be very helpful to determine a standardized set of sensitivity measures, irrespective of design. (Source: Magnetic Resonance Materials in Physics, Biology and Medicine)
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - May 18, 2023 Category: Materials Science Source Type: research

RF-induced heating of interventional devices at 23.66  MHz
ConclusionAt low fields, interventions with shorter insertion lengths such as hepatic catheterizations result in less RF-induced heating than coronary interventions. The maximum temperature increase depends on body coil design. (Source: Magnetic Resonance Materials in Physics, Biology and Medicine)
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - May 17, 2023 Category: Materials Science Source Type: research

US regulatory considerations for low field magnetic resonance imaging systems
AbstractAlthough there has been a resurgence of interest in low field magnetic resonance imaging (MRI) systems in recent years, low field MRI is not a new concept. FDA has a long history of evaluating the safety and effectiveness of MRI systems encompassing a wide range of field strengths. Many systems seeking marketing authorization today include new technological features (such as artificial intelligence), but this does not fundamentally change the regulatory paradigm for MR systems. In this review, we discuss some of the US regulatory considerations for low field magnetic resonance imaging (MRI) systems, including appli...
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - May 16, 2023 Category: Materials Science Source Type: research

Correction to: Scaling the mountains: what lies above 7 Tesla magnetic resonance?
(Source: Magnetic Resonance Materials in Physics, Biology and Medicine)
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - May 16, 2023 Category: Materials Science Source Type: research

A theoretical and experimental investigation on a volume coil with slotted end-rings for rat MRI at 7 T
DiscussionThere is remarkable agreement among the theoretical, numerical and experimental sensitivity values, which all demonstrate that the coil performance for MR imaging of small rodents can be improved using slotted end-rings. (Source: Magnetic Resonance Materials in Physics, Biology and Medicine)
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - May 15, 2023 Category: Materials Science Source Type: research

Ramping down a clinical 3  T scanner: a journey into MRI and MRS at 0.75 T
We describe the ramp-down procedure and necessary software and hardware changes to the system.ResultsApart from presenting system characterization results, we show in vivo examples of cardiac cine imaging, abdominal two- and three-point Dixon-type water/fat separation, water/fat-separated MR Fingerprinting, and point-resolved spectroscopy. In addition, the ramp-down approach allows unique comparisons of, e.g., gradient fidelity of the same MR system operated at different field strengths using the same receive chain, gradient coils, and amplifiers.DiscussionRamping down an existing MR system may be seen as a viable alternat...
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - May 12, 2023 Category: Materials Science Source Type: research

$$B_1$$ Field inhomogeneity correction for qDESS $$T_2$$ mapping: application to rapid bilateral knee imaging
ConclusionThe study showed that\(B_1\) correction could mitigate variations driven by the sensitivity of the qDESS\(T_2\) mapping method to\(B_1\), therefore, increasing the sensitivity to detect real biological changes. The proposed method may improve the robustness of bilateral qDESS\(T_2\) mapping, allowing for an accurate and more efficient evaluation of OA pathways and pathophysiology through longitudinal and cross-sectional studies. (Source: Magnetic Resonance Materials in Physics, Biology and Medicine)
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - May 4, 2023 Category: Materials Science Source Type: research

Topology-based radiomic features for prediction of parotid gland cancer malignancy grade in magnetic resonance images
ConclusionThis study indicated that topology-based radiomic features could be feasible for the noninvasive prediction of the malignancy grade of PGCs. (Source: Magnetic Resonance Materials in Physics, Biology and Medicine)
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - April 20, 2023 Category: Materials Science Source Type: research

Optimization design of a permanent magnet used for a low field (0.2  T) movable MRI system
DiscussionThe proposed permanent magnet design significantly reduces the magnet ’s weight compared with the conventional magnet structure and shows promise in promoting the development of lowfield compact MRI systems. (Source: Magnetic Resonance Materials in Physics, Biology and Medicine)
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - April 20, 2023 Category: Materials Science Source Type: research

Magnetic resonance imaging at 9.4  T: the Maastricht journey
This article reviews some of the 9.4 T work done in Maastricht. Functional imaging experiments included blood oxygen ation level-dependent (BOLD) and blood-volume weighted (VASO) fMRI using different readouts. BOLD benefits from shorter T2* at 9.4  T while VASO from longer T1. We show examples of both ex vivo and in vivo anatomical imaging. For many applications, pTx and optimized coils are essential to harness the full potential of 9.4  T. Our experience shows that, while considerable effort was required compared to our 7 T scanner, we could obtain high-quality anatomical and functional data, which illustrates the pot...
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - April 20, 2023 Category: Materials Science Source Type: research

Preparation of MnO2@poly-(DMAEMA-co-IA)-conjugated methotrexate nano-complex for MRI and radiotherapy of breast cancer application
ConclusionWe draw the conclusion that using MnO2@Poly(DMAEMA-Co-IA)-MTX NPs in MR imaging and combination radiotherapy may be a successful method for imaging and radiation therapy of hypoxia cells. (Source: Magnetic Resonance Materials in Physics, Biology and Medicine)
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - April 19, 2023 Category: Materials Science Source Type: research

Scaling the mountains: what lies above 7 Tesla magnetic resonance?
(Source: Magnetic Resonance Materials in Physics, Biology and Medicine)
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - April 19, 2023 Category: Materials Science Source Type: research

Near-wall hemodynamic parameters quantification in in vitro intracranial aneurysms with 7  T PC-MRI
ConclusionsWe showed that the elevated signal-to-noise ratio arising from 7  T PC-MRI enabled to resolve high and low WSS patterns with a high degree of detail. (Source: Magnetic Resonance Materials in Physics, Biology and Medicine)
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - April 19, 2023 Category: Materials Science Source Type: research