Biopsy-based optimization and calibration of a signal-intensity-ratio-based MRI method (1.5 Tesla) in a dextran-iron loaded mini-pig model, enabling estimation of very high liver iron concentrations

DiscussionThe wider measuring range is likely caused by lesser sensitivity of the SE sequence to iron, due to shorter TE, leading to later signal loss at high LIC, allowing evaluation of most severe hepatic iron overload. Validation in iron-loaded patients is necessary.

http://link.springer.com/10.1007/s10334-021-00998-x

Source: Magnetic Resonance Materials in Physics, Biology and Medicine - January 17, 2022 Category: Materials Science Source Type: research