Journal of Oral and Maxillofacial Surgery This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Clinical and Histomorphometric Outcomes of Bone Block Grafts Used for Alveolar Bone Regeneration: A Systematic Review
Despite advances in the field of implantology, severe alveolar bone  deficiencies still present a challenge to surgeons. Autogenous bone has long been considered the gold standard and most effective in bone regeneration due to its osteoconductive, osteoinductive, and osteogenic characteristics. Harvesting autogenous bone block grafts is associated with risk of dono r site morbidity, prolonged treatment time, possibility of injury to adjacent structures, and may involve a general anesthetic with hospitalization. (Source: Journal of Oral and Maxillofacial Surgery)
Source: Journal of Oral and Maxillofacial Surgery - September 1, 2023 Category: ENT & OMF Authors: Pav Chana, Julian Yates, Lucy O'Malley Source Type: research

Evaluation of the Local and Systemic Effects of Oral Submucosal Ketamine
Few therapeutic alternatives exist for patients with allergies to amide and ester local anesthetics. While diphenhydramine ’s efficacy has been verified experimentally, its use is associated with significantly decreased duration of pulpal anesthesia and increased subjective pain scores during exodontia procedures as compared to prilocaine.1 Additionally, complications such as confusion, diplopia, and skin necrosis hav e been reported. Several investigators have examined ketamine’s use as a postoperative analgesic adjunct when combined with commonly used amide anesthetics during oral surgery procedures. (Source: Journal...
Source: Journal of Oral and Maxillofacial Surgery - September 1, 2023 Category: ENT & OMF Authors: Yu Jin Lee, Allen F. Champion Source Type: research

Investigating the Safety of Outpatient Sedation in Pediatric Oral and Maxillofacial Surgery at an Urban Academic Center
This study seeks to address that deficiency by investigating the safety of OMS outpatient sedation in the pediatric population. (Source: Journal of Oral and Maxillofacial Surgery)
Source: Journal of Oral and Maxillofacial Surgery - September 1, 2023 Category: ENT & OMF Authors: Marvin Thomas, Joohoon Lee, Vasiliki Karlis Source Type: research

Marijuana ’s Effect on Dosage Requirements During Sedation in Oral and Maxillofacial Surgery
This study is a retrospective cohort study. The study sample included patients from Oct. 1, 2022, to Dec. 31, 2022, who underwent sedation at Kings County Hospital OMS clinic. Fifty-nine total patients were included in the study. (Source: Journal of Oral and Maxillofacial Surgery)
Source: Journal of Oral and Maxillofacial Surgery - September 1, 2023 Category: ENT & OMF Authors: Paul Addamo, Gregory Yunov, Radislav Meylikh, Yuriy Yusupov Source Type: research

A Comparison of the Effects of EMLA Cream and Topical 5% Lidocaine on Discomfort During Palatal Injection
Local anesthesia of the palatal mucosa is crucial for painless penetration of soft palate tissue during dental procedures. The administration of anesthetic agents to the palate can be very painful due to the region's mucosa being closely attached to the periosteum bone and having multiple peripheral nerves. The palatal mucosa is a commonly used area for local anesthesia and serves as an accurate test for assessing the effectiveness of topical anesthetics. The purpose of this study was to compare the efficacy of EMLA cream and lidocaine ointment in reducing the amount of injection pain experienced by the greater palatine ne...
Source: Journal of Oral and Maxillofacial Surgery - September 1, 2023 Category: ENT & OMF Authors: Mahtasadat Afradeh, Shahrooz Shafaeefard, Mehdi Sezavar, Zeinab Darajati Source Type: research

Assessment and Validation of Preoperative Three-Dimensional Volumetric Analysis to Predict Bone Graft Success in Alveolar Cleft Reconstruction
Cleft lip and palate is the most common craniofacial congenital anomaly in the world, affecting 1 in 700 live births.1 Although alveolar bone grafting (ABG) with autologous iliac crest bone graft (ICBG) remains the standard of care to treat these bony defects, recombinant human bone morphogenetic protein-2 (rhBMP-2) with demineralized bone matrix (DBM) has shown equal graft success compared to ICBG.2 Despite significant advancements in ABG, reported graft success rates vary widely for both types ranging from 60-80% for ICBG and 54-90% for rhBMP-2. (Source: Journal of Oral and Maxillofacial Surgery)
Source: Journal of Oral and Maxillofacial Surgery - September 1, 2023 Category: ENT & OMF Authors: Simon Youn, Idean Roohani, Sarah Alfeerawi, Pasha Shakoori, Collean Trotter, Dylan Choi, Artur Fahradyan, Mark M. Urata, William P. Magee, Jeffrey A. Hammoudeh Source Type: research

Validation of Accuracy Analysis for Zygomatic Dental Implants
Measuring the accuracy of dental implants is important not only for the technical refinement of the individual clinician, but also for developing novel techniques to narrow the gap between the surgical plan and the actual outcome. Zygomatic dental implants (ZI) pose greater challenges because small errors can propagate significantly at the apical level, which commonly has important structures such as the orbital contents and deep vessels. Current analysis methods are largely limited to manual measurement of linear and angular errors, which is prone to human error and bias. (Source: Journal of Oral and Maxillofacial Surgery)
Source: Journal of Oral and Maxillofacial Surgery - September 1, 2023 Category: ENT & OMF Authors: Sebastian Graca, Michael D. Han, Michael Miloro Tags: Dental Implants Source Type: research

Retrospective Cohort Study of the Effects of NOACs on Postoperative Bleeding Following Dental Extraction
Novel oral anticoagulants (NOACs) are a revolutionary tool to decrease morbidity among patients with a high risk of thromboembolic events. Perioperative management of anticoagulants such as Warfarin have been well studied, but guidelines for perioperative management of patients on NOACs remains controversial. In part, this issue stems from a lack of a standardized and affordable monitoring test, such as an INR (Berton et al, 2019). Studies show that NOACs lead to a bleeding risk synonymous with an INR of 2-4, a moderately safe value for most basic dentoalveolar extractions (Brennan et al, 2020). (Source: Journal of Oral an...
Source: Journal of Oral and Maxillofacial Surgery - September 1, 2023 Category: ENT & OMF Authors: Wasek Chowdhury, Shravan K. Renapurkar, Dan Q. Tran, Dean M. DeLuke, Alexandra Glickman, Michael Clay Source Type: research

The Utility of Cone-Beam Computed Tomography for the Evaluation of Invasion by Mandibular Squamous Cell Carcinoma
The degree of bone involvement in mandibular squamous cell carcinoma has a significant impact on surgical planning. While precise evaluation of bone involvement is needed, no single imaging method is able to detect the extent of invasion with complete reliability.1,2 The purpose of this preliminary study was to determine the utility of cone-beam computed tomography (CBCT) for the evaluation of invasion by mandibular squamous cell carcinoma. (Source: Journal of Oral and Maxillofacial Surgery)
Source: Journal of Oral and Maxillofacial Surgery - September 1, 2023 Category: ENT & OMF Authors: Jason Wahidi, Timothy W. Neal, Thomas Schlieve, Roderick Y. Kim, Fayette C. Williams Tags: Head & Neck Source Type: research

Free Fibular Flap Neomandible Density Changes in a Previously Irradiated Tissue Bed
Microvascular fibula free flaps have become the gold standard for mandibular reconstruction. Various indications for maxillofacial reconstruction via microvascular fibula free flaps include benign tumors/cysts (ameloblastomas, odontogenic keratocysts, dentigerous cysts), osteoradionecrosis, and trauma. Our study set out to analyze the bone density of a microvascular fibula free flap neomandible reconstruction. Previous studies have evaluated these bone density changes; however, no study has compared the density changes of fibula reconstructions due to benign indications versus previously irradiated tissue beds. (Source: Jo...
Source: Journal of Oral and Maxillofacial Surgery - September 1, 2023 Category: ENT & OMF Authors: Jeremiah D'Anna, Andrew Salama, David Hirsch, Denis Knobel Source Type: research

Developing Novel Therapeutics for Oral Cancer Leveraging Drosophila Models
The prevalence of oral squamous cell carcinoma (OSCC) has been increasing worldwide. Surgical resection and chemoradiotherapy are the main OSCC treatments currently, but their effectiveness is limited. One of their major problems is the decline in patients ’ quality of life due to oral dysfunction caused by the extensive resection and oral mucositis. Although targeted therapies have emerged for treating OSCC and have improved the patients’ survival rate, these therapies also cause severe side effects that hamper completion of the regimens. (Source: Journal of Oral and Maxillofacial Surgery)
Source: Journal of Oral and Maxillofacial Surgery - September 1, 2023 Category: ENT & OMF Authors: Taku Kimura, Masahiro Sonoshita, Yoshimasa Kitagawa Source Type: research

Tumor Microenvironment Modulation by Cetuximab and its Contribution to Subsequent Immune-Checkpoint Inhibition Therapy in Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma
Current clinical and observational evidence supports the EXTREME regimen as 1 of the standards of care for patients with recurrent or metastatic head and neck squamous cell carcinoma (R/M HNSCC) followed by the administration of immune checkpoint inhibitors (ICIs). In addition to the inhibition of the endothelial growth factor receptor (EGFR) pathway, cetuximab-mediated EGFR blockade has been shown to modulate tumor microenvironment (TME) characteristics, such as antibody-dependent cellular cytotoxicity (ADCC) activity, cytotoxic T-lymphocyte (CTL) infiltration into the tumor, anti-angiogenesis activity, and cytokine secre...
Source: Journal of Oral and Maxillofacial Surgery - September 1, 2023 Category: ENT & OMF Authors: Kohei Okuyama, Tomofumi Naruse, Souichi Yanamoto Source Type: research

Identifying Great Auricular Nerve via Bony Landmarks: A Cadaver Study
Great Auricular Nerve (GAN) is the most commonly sacrificed nerve during rhydectomies due to anatomical variation and lack of a reliable landmark.1 Even though quality of life does not decrease, surgeons should strive to avoid iatrogenic injury to the nerve. The aim of this study is to utilize 2 bony landmarks for the GAN to determine which if there is a reliable, bony anatomical landmark during surgery, specifically calculating the ratio at which the angle of the mandible (gonion) and tip of the mastoid process bisect GAN. (Source: Journal of Oral and Maxillofacial Surgery)
Source: Journal of Oral and Maxillofacial Surgery - September 1, 2023 Category: ENT & OMF Authors: May Lin, Dale A. Baur, Guneet Singh Source Type: research

Obstructive Sleep Apnea in Young Adults Undergoing Orthognathic Surgery: Impact on Length of Stay and Hospital Admission Costs
Length of hospital stay (LOS) significantly affects costs and is a frequently employed metric for quality of care. Obstructive sleep apnea (OSA) has been demonstrated to elevate the risk of postoperative complications and prolong LOS in patients undergoing orthognathic surgery. However, previous studies have predominantly focused on OSA patients amongst older adults and those with underlying comorbidities. A paucity of data exists regarding younger patients with OSA undergoing orthognathic surgery. (Source: Journal of Oral and Maxillofacial Surgery)
Source: Journal of Oral and Maxillofacial Surgery - September 1, 2023 Category: ENT & OMF Authors: Samuel Daley, Syed Abbas Raza, Hunter Martin, Andrew Salama Tags: Obstructive Sleep Apnea (OSA) Source Type: research

OSA as a Consideration in Upper Jaw Surgery
Segmental LeFort I osteotomy is useful for the management of transverse and vertical maxillary discrepancies. However, some patients in need of orthognathic surgery may also have risk factors for obstructive sleep apnea (OSA) in which clinicians must be conscious about how surgery will affect the soft palate, the most commonly involved area of obstruction (77.9%).1 Furthermore, in patients who need palatal expansion and maxillary advancement for the purpose of increasing airway volume and treating OSA, it is important to consider whether the segmental LeFort I osteotomy will provide similar advancement of the palate compar...
Source: Journal of Oral and Maxillofacial Surgery - September 1, 2023 Category: ENT & OMF Authors: Vania Firmalino, Thomas Kim, Joshua A. Stone, Stanley Y. Liu Source Type: research