Assessment and Validation of Preoperative Three-Dimensional Volumetric Analysis to Predict Bone Graft Success in Alveolar Cleft Reconstruction

Cleft lip and palate is the most common craniofacial congenital anomaly in the world, affecting 1 in 700 live births.1 Although alveolar bone grafting (ABG) with autologous iliac crest bone graft (ICBG) remains the standard of care to treat these bony defects, recombinant human bone morphogenetic protein-2 (rhBMP-2) with demineralized bone matrix (DBM) has shown equal graft success compared to ICBG.2 Despite significant advancements in ABG, reported graft success rates vary widely for both types ranging from 60-80% for ICBG and 54-90% for rhBMP-2.
Source: Journal of Oral and Maxillofacial Surgery - Category: ENT & OMF Authors: Source Type: research