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Relationship of cardiovascular risk factors, pericardial fat, and carotid thickness with coronary plaque type in patients with diabetes mellitus
ConclusionIncreased PFV showed significant and independent association with mixed coronary plaques development, which suggests that PFV may be used as an imaging marker for early detection of increased risk for future coronary events in patients with DM. (Source: Journal of Diabetes and Metabolic Disorders)
Source: Journal of Diabetes and Metabolic Disorders - February 13, 2023 Category: Endocrinology Source Type: research

Impact of essential metals on insulin sensitivity and fetuin in obesity-related type 2 diabetes pathogenesis
ConclusionsMg play a significant role in obesity-related T2DM pathogenesis and complications via Fet-A, insulin sensitivity, and resistance modifications. (Source: Journal of Diabetes and Metabolic Disorders)
Source: Journal of Diabetes and Metabolic Disorders - February 8, 2023 Category: Endocrinology Source Type: research

The association of plant-based dietary pattern with general and abdominal obesity: a large cross-sectional study
ConclusionIn the present study, no association was observed between PDI and general and abdominal obesity in the Iranian adult population. (Source: Journal of Diabetes and Metabolic Disorders)
Source: Journal of Diabetes and Metabolic Disorders - January 28, 2023 Category: Endocrinology Source Type: research

Circulating chemerin level and the risk of nonalcoholic fatty liver disease: a systematic review and meta-analysis
ConclusionThere were no significant differences in chemerin levels between the NAFLD and healthy adults; however, the association was significant in children. However, due to the lack of studies in this age group, the conclusion should be made with caution. (Source: Journal of Diabetes and Metabolic Disorders)
Source: Journal of Diabetes and Metabolic Disorders - January 28, 2023 Category: Endocrinology Source Type: research

Association of ABCC8 gene variants with response to sulfonylurea in type 2 diabetes mellitus
ConclusionThe rs1799854 and rs757110 variants of the ABCC8 gene had no significant influence on response to SFUs treatment. (Source: Journal of Diabetes and Metabolic Disorders)
Source: Journal of Diabetes and Metabolic Disorders - January 28, 2023 Category: Endocrinology Source Type: research

The Effect of a cognitive behavioral program based on an interactive application on serum glucose levels and HbA1C of family members of patients with type 2 diabetes: a study protocol for a randomized clinical trial
DiscussionIf an application-based cognitive-behavioral program changes the lifestyle, serum glucose levels, and HbA1C, it can be recommended to families of diabetics. (Source: Journal of Diabetes and Metabolic Disorders)
Source: Journal of Diabetes and Metabolic Disorders - January 28, 2023 Category: Endocrinology Source Type: research

Effect of Oleanolic acid administration on hepatic AMPK, SIRT-1, IL-6 and NF- κB levels in experimental diabetes
ConclusionThe OA treatment can be considered to alleviate oxidative stress and reduce severity of inflammation in hepatocytes in the diabetic subjects. (Source: Journal of Diabetes and Metabolic Disorders)
Source: Journal of Diabetes and Metabolic Disorders - January 28, 2023 Category: Endocrinology Source Type: research

The risk of experiencing depression among older adults in India: A cross-sectional study
ConclusionElderly population (60  +) is at higher risk of experiencing depression due to diabetes. Therefore, public health care awareness should be raised, particularly among endocrinologists or specialist doctors who provide treatment at the tertiary-care hospitals in India. The health care experts should refer/recommend the di abetic patients to screen for depressive symptoms. (Source: Journal of Diabetes and Metabolic Disorders)
Source: Journal of Diabetes and Metabolic Disorders - January 19, 2023 Category: Endocrinology Source Type: research

Influence of smartphone-based physical activity intervention on executive functions and cardiometabolic disease risk in obese young adults: a pilot randomised controlled trial
ConclusionShort-term smartphone-based physical activity programs may offer favourable cognitive benefits to young adults; however, the weight loss benefits remain unconvincing.Trial RegistrationThe study was registered prospectively with the Clinical Trials Registry of India (CTRI/2022/02/040202). (Source: Journal of Diabetes and Metabolic Disorders)
Source: Journal of Diabetes and Metabolic Disorders - January 13, 2023 Category: Endocrinology Source Type: research

Melatonin improves liver and pancreatic tissue injuries in diabetic rats: role on antioxidant enzymes
ConclusionThis work shows that in long-term oxidative stress conditions caused by STZ-induced diabetes, either Mel or Mel  + insulin administration may improve the deteriorated oxidant/antioxidant system in both the liver and pancreas tissues. These results suggested that Mel alone or Mel + insulin treatments might have a significant role in protecting against liver and pancreatic damage in STZ diabetic rats vi a different antioxidant effects. (Source: Journal of Diabetes and Metabolic Disorders)
Source: Journal of Diabetes and Metabolic Disorders - January 13, 2023 Category: Endocrinology Source Type: research

Health literacy and self-efficacy of the elderly with diabetes
ConclusionHealth literacy is directly related to self-efficacy in older people with diabetes. (Source: Journal of Diabetes and Metabolic Disorders)
Source: Journal of Diabetes and Metabolic Disorders - January 13, 2023 Category: Endocrinology Source Type: research

Disparities in the prevalence of metabolic syndrome between Iranian industrial workers and university staff
ConclusionBased on the findings of this study, the prevalence of metabolic syndrome in university staff was almost double that in industry workers. At first glance, the physical activity of most automotive, industrial workers seems to be the main reason for this difference; however, a prevalence of about twice implies further factors. According to the authors, the legal implementation of monitoring, promotion, and surveillance programs of occupational health, in industrial environments can be a factor accounting for a significant difference in the prevalence of metabolic syndrome between the two populations observed. The a...
Source: Journal of Diabetes and Metabolic Disorders - January 11, 2023 Category: Endocrinology Source Type: research

Effect of bread fortification with pomegranate peel powder on glycemic indicators, antioxidant status, inflammation and mood in patients with type 2 diabetes: study protocol for a randomized, triple-blind, and placebo-controlled trial
DiscussionThis trial will provide novel data on the impact of fortified bread with PPP on metabolic profile and mood state of patients with type 2 diabetes. The results will demonstrate the potential of such intervention in glycemic indices, antioxidant status, inflammation and mood in these patients.Trial RegistrationTrial is registered in the Iranian Registry of Clinical Trials (ID: IRCT20191209045672N1). Date of registration 21/09/2020.https://en.irct.ir/trial/48132. (Source: Journal of Diabetes and Metabolic Disorders)
Source: Journal of Diabetes and Metabolic Disorders - January 5, 2023 Category: Endocrinology Source Type: research

Inactive matrix Gla protein in relation to diabetic retinopathy in type 2 diabetes
ConclusionsInactive MGP was found to be related to DR, insulin resistance and other dysmetabolic risk factors. These findings highlight that inactive MGP may be a significant contributor to the pathogenesis, evolution, and progression of DR. (Source: Journal of Diabetes and Metabolic Disorders)
Source: Journal of Diabetes and Metabolic Disorders - January 5, 2023 Category: Endocrinology Source Type: research

Underlying biochemical effects of intermittent fasting, exercise and honey on streptozotocin-induced liver damage in rats
AbstractPurposeDerangements of liver transcriptional factors and enzymes have important implications in diabetes-induced related complications. Hence, this study which consists of two experimental phases was aimed at evaluating the possible underlying molecular mechanisms of intermittent fasting (IF), exercise starvation and honey in streptozotocin (STZ)-mediated liver damage in diabetic rats.MethodsThe diabetic rats were treated orally with distilled water (0.5  ml/kg), IF, starvation and honey at 1 g/kg body weight in the non-diabetic phase for four (4) weeks. After STZ injections, four (4) weeks of IF, exercise, starv...
Source: Journal of Diabetes and Metabolic Disorders - January 4, 2023 Category: Endocrinology Source Type: research