Melatonin improves liver and pancreatic tissue injuries in diabetic rats: role on antioxidant enzymes

ConclusionThis work shows that in long-term oxidative stress conditions caused by STZ-induced diabetes, either Mel or Mel  + insulin administration may improve the deteriorated oxidant/antioxidant system in both the liver and pancreas tissues. These results suggested that Mel alone or Mel + insulin treatments might have a significant role in protecting against liver and pancreatic damage in STZ diabetic rats vi a different antioxidant effects.
Source: Journal of Diabetes and Metabolic Disorders - Category: Endocrinology Source Type: research