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The first nationally and sub-nationally representative non-communicable diseases cohort study in Iran: Iran Cohort Study (ICS) protocol
ConclusionThe present study is the first comprehensive national and sub-national representative cohort study on NCDs ’ risk factors in Iranian adults. The results could be used for promotion of health planning and also future complementary studies and programs. (Source: Journal of Diabetes and Metabolic Disorders)
Source: Journal of Diabetes and Metabolic Disorders - November 2, 2022 Category: Endocrinology Source Type: research

Management goal achievements of diabetes care in Iran: study profile and main findings of DiaCare survey
ConclusionsThis population-based study provided representative information about diabetes care in Iran. The high prevalence of diabetes and low proportion of diabetes control in Iran implies that it is necessary to identify factors associated with poor treatment goal achievements. Besides, general improvements in management and care of diabetes are mandatory. (Source: Journal of Diabetes and Metabolic Disorders)
Source: Journal of Diabetes and Metabolic Disorders - November 2, 2022 Category: Endocrinology Source Type: research

Effects of age on polycythemia, cardiometabolic risk and their associations in middle-aged men
ConclusionThe prevalence of polycythemia was higher and its associations with cardiometabolic risk such as high LDL-C/HDL-C ratio and metabolic syndrome were stronger in the youngest group than in the older groups. The results suggest that early detection and correction of polycythemia are more effective than its later correction for prevention of cardiovascular disease in middle-aged men. (Source: Journal of Diabetes and Metabolic Disorders)
Source: Journal of Diabetes and Metabolic Disorders - October 31, 2022 Category: Endocrinology Source Type: research

Design, development, and usability evaluation of a smartphone-based application for nutrition management in patients with type II diabetes
ConclusionGiven the desirable evaluation of the app by patients, physicians, and IT experts, it can be concluded that the developed app has the required functionalities for nutrition management of patients with type II diabetes. Smartphone-based apps appear to be able to improve self-management, the quality of care and health in patients with diabetes, and reduce many of their unnecessary visits to healthcare centers, and costs. (Source: Journal of Diabetes and Metabolic Disorders)
Source: Journal of Diabetes and Metabolic Disorders - October 31, 2022 Category: Endocrinology Source Type: research

Association of vaspin rs2236242 with type 2 diabetes mellitus and obesity: a meta-analysis of case-control studies
ConclusionOur meta-analysis provides evidence of significant association between vaspin rs2236242 and reduced risk of obesity but not T2DM. (Source: Journal of Diabetes and Metabolic Disorders)
Source: Journal of Diabetes and Metabolic Disorders - October 31, 2022 Category: Endocrinology Source Type: research

Oral administration of nano-tyrosol reversed the diabetes-induced liver damage in streptozotocin-induced diabetic rats
ConclusionThe results of the present study suggested the beneficial effects of Tyrosol and especially Nano-tyrosol on decreasing the adverse effects of diabetes. (Source: Journal of Diabetes and Metabolic Disorders)
Source: Journal of Diabetes and Metabolic Disorders - October 31, 2022 Category: Endocrinology Source Type: research

Revision of sex hormone replacement therapy for CKD Pediatric cases
(Source: Journal of Diabetes and Metabolic Disorders)
Source: Journal of Diabetes and Metabolic Disorders - October 31, 2022 Category: Endocrinology Source Type: research

Association of glutathione S-transferase M1 and T1 polymorphisms on the susceptibility of diabetic retinopathy in the Bangladeshi population
ConclusionsTaken together, these findings suggest the potential role of GSTT1 deletion mutation as a risk factor for the vulnerability of DR among T2DM patients in the Bangladeshi population. (Source: Journal of Diabetes and Metabolic Disorders)
Source: Journal of Diabetes and Metabolic Disorders - October 28, 2022 Category: Endocrinology Source Type: research

Association of fat mass and obesity-associated (FTO) gene polymorphisms with non-communicable diseases (NCDs) in the Iranian population: A systematic review of observational studies
ConclusionFTO gene polymorphism appears to play a role in the occurrence of NCDs. Some of the study results may be misleading due to ethnic differences and the effect of other genetic factors on disease onset, which needs to be investigated further. Finally,FTO gene polymorphisms can be studied as a preventive or therapeutic target. (Source: Journal of Diabetes and Metabolic Disorders)
Source: Journal of Diabetes and Metabolic Disorders - October 24, 2022 Category: Endocrinology Source Type: research

Safety and effectiveness of newer antidiabetic medications during Ramadan fasting and safety of Ramadan fasting after bariatric surgery
ConclusionsThe newer diabetes medications such as GLP-1 agonists, DPP-4 inhibitors, SGLT-2 inhibitors, and new Insulin therapy are thought to be safe and effective during fasting of Ramadan. These medications are associated with a reduction in HbA1c, body weight, systolic blood pressure and risk of hypoglycemia during Ramadan fasting. However, further studies with larger sample size are needed to confirm the efficacy and safety of these newer medications during Ramadan fasting. Individuals with Bariatric surgery should seek advice and approval to fast from the bariatric dietician, physician, and surgeon before the beginnin...
Source: Journal of Diabetes and Metabolic Disorders - October 24, 2022 Category: Endocrinology Source Type: research

The effects of high intensity interval training induced H2O2, Nrf2 changes on antioxidants factors in type 2 diabetes
ConclusionOur results provide evidence that HIIT causes an increase in oxidative stress levels, which ultimately the body responds to increased antioxidant levels. Therefore, it is suggested that these indicators (HIIT and H2O2, Nrf2) can be considered as a therapeutic target for type 2 diabetic patients. (Source: Journal of Diabetes and Metabolic Disorders)
Source: Journal of Diabetes and Metabolic Disorders - October 21, 2022 Category: Endocrinology Source Type: research

What I felt as a diabetes fatigue survivor: a phenomenology study
ConclusionParticipants with T2DM who experienced diabetes fatigue reported negative effects on their life, especially on health, functional daily activity, and finances. The results of this study can provide information for nurses and other healthcare providers to promote interventions for patients with T2DM, such as modifying lifestyle, self-acceptance, and self-efficacy. (Source: Journal of Diabetes and Metabolic Disorders)
Source: Journal of Diabetes and Metabolic Disorders - October 20, 2022 Category: Endocrinology Source Type: research

Post COVID-19 neuropsychiatric complications and therapeutic role for TNF- α inhibitors: a case series study
ConclusionsTo our knowledge, this report is the first case series study that suggests TNF inhibitors in the treatment of post-COVID-19 syndrome, especially neuropsychological complications. However, future studies should evaluate the best therapeutic options for this syndrome. (Source: Journal of Diabetes and Metabolic Disorders)
Source: Journal of Diabetes and Metabolic Disorders - October 15, 2022 Category: Endocrinology Source Type: research

Correction to: Intestinal Microbiota Composition in Iranian Diabetic, Pre-diabetic and Healthy Individuals
(Source: Journal of Diabetes and Metabolic Disorders)
Source: Journal of Diabetes and Metabolic Disorders - October 15, 2022 Category: Endocrinology Source Type: research

Is elevated ALT associated with lifestyle risk factors? A population-based survey
ConclusionAs elevated ALT was associated with several lifestyle risk factors, stewardship programs should be established to modify lifestyle risk factors, such as abdominal obesity and physical inactivity. (Source: Journal of Diabetes and Metabolic Disorders)
Source: Journal of Diabetes and Metabolic Disorders - October 12, 2022 Category: Endocrinology Source Type: research