Regulate Artificial Intelligence in Health Care by Prioritizing Patient Outcomes
This Viewpoint argues for a shift in focus by the White House executive order on artificial intelligence from regulatory targets to patient outcomes. (Source: JAMA)
Source: JAMA - February 27, 2024 Category: General Medicine Source Type: research
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(Source: JAMA)
Source: JAMA - February 27, 2024 Category: General Medicine Source Type: research
Poetry in Motion
A recent survey suggests that people with functional impairment who do not identify as having a disability report less respect from clinicians compared to people without impairments; they also perceive the unfair treatment experienced by disabled –identified patients. Might poetry help illuminate and ameliorate these kinds of health inequities? In “Safiri’s Dance,” we experience a stunning performance that suggests it can. The poem sets the stage in a modest hospital chapel; short, end-stopped lines and unadorned language premise ord inariness. As the performance begins, we feel movement conveyed in the more metric...
Source: JAMA - February 27, 2024 Category: General Medicine Source Type: research
Safiri ’s Dance
Hospital chapel. Swahili service. Small, crowded, cinder blocks. “Ms. Kimutai has a special number to share.” Climbs on stage. Carefully applied makeup. Bright colors, best dress. Background music: “Streams of mercy, never ceasing.” Sways, arms raised. Flowing dress swirls. Graceful, ardent, moving. Final note lingers. Glowing upward beaming smile. Re-str aps prosthetic legs with forearm stubs. (Source: JAMA)
Source: JAMA - February 27, 2024 Category: General Medicine Source Type: research
Long-Term Outcomes of Medical Management vs Bariatric Surgery in Type 2 Diabetes
This pooled analysis including 4 trials examines the long-term glycemic control and safety of bariatric surgery compared with medical/lifestyle management of type 2 diabetes. (Source: JAMA)
Source: JAMA - February 27, 2024 Category: General Medicine Source Type: research
Changes in Health Care Workers ’ Economic Outcomes Following Medicaid Expansion
This study examines the difference in health care worker compensation between states that expanded and those that did not expand Medicaid after the passage of the Affordable Care Act. (Source: JAMA)
Source: JAMA - February 27, 2024 Category: General Medicine Source Type: research
Cefepime vs Piperacillin-Tazobactam for Acute Infection in Hospitalized Adults —Reply
In Reply Noting the differences in anerobic coverage between cefepime and piperacillin-tazobactam, Dr Chanderraj and colleagues inquire how commonly clinicians in our recent ACORN trial elected to co-administer antibiotics with anerobic coverage (eg, metronidazole or clindamycin) to patients in the cefepime group vs the piperacillin-tazobactam group. In the 14 days after enrollment, 564 patients (46.5%) in the cefepime group and 248 patients (19.1%) in the piperacillin-tazobactam group received either metronidazole or clindamycin, of which 535 (44.1%) and 173 (13.3%), respectively, received them during the first 3 days aft...
Source: JAMA - February 27, 2024 Category: General Medicine Source Type: research
Review of Evaluation and Treatment of Knee Pain —Reply
In Reply We appreciate Dr Misseri and colleagues ’ interest in our Review article. They raise a relevant point about RFA as a potential treatment option for managing knee osteoarthritis pain. Research on this topic has mostly been published in anesthesiology and pain medicine journals, likely because specialist pain management physicians usually perform this procedure. Few studies about RFA have been published in rheumatology, orthopedic, and osteoarthritis journals, at least until very recently. (Source: JAMA)
Source: JAMA - February 27, 2024 Category: General Medicine Source Type: research
Use of Landiolol for Patients With Septic Shock and Organ Failure –Reply
In Reply We thank Dr Mantzarlis and colleagues for their interest in the STRESS-L study. It is worth highlighting that our research hypothesis was that more selective β1-receptor blockade would bring about myocardial protection and immunomodulation to confer benefits to a high-risk population with septic shock. Tachycardia was used as a surrogate to define this high-risk population. We did not mandate Svo2 or other cardiac output monitoring in our protocol. The trial was stopped after only 126 of a planned 340 patients were recruited. (Source: JAMA)
Source: JAMA - February 27, 2024 Category: General Medicine Source Type: research
Cefepime vs Piperacillin-Tazobactam for Acute Infection in Hospitalized Adults
To the Editor A recent randomized clinical trial compared empirical cefepime vs piperacillin-tazobactam in adult patients who presented to the hospital with suspected infection. However, we urge caution in accepting the authors ’ conclusion that empirical use of cefepime resulted in more neurological dysfunction vs piperacillin-tazobactam. This conclusion was based on the finding that patients in the cefepime group experienced fewer days alive and free of delirium and coma within 2 weeks, with a mean difference of only 0 .3 days (odds ratio [OR], 0.79 [95% CI, 0.65-0.95]). (Source: JAMA)
Source: JAMA - February 27, 2024 Category: General Medicine Source Type: research
Cefepime vs Piperacillin-Tazobactam for Acute Infection in Hospitalized Adults
To the Editor We applaud the execution and reporting of the Antibiotic Choice on Renal Outcomes (ACORN) pragmatic, randomized clinical trial of cefepime vs piperacillin-tazobactam in hospitalized adults with suspected infection in the emergency department or medical intensive care unit. (Source: JAMA)
Source: JAMA - February 27, 2024 Category: General Medicine Source Type: research
Cefepime vs Piperacillin-Tazobactam for Acute Infection in Hospitalized Adults
To the Editor A recent randomized clinical trial reported that among adults hospitalized with acute infection, patients treated with cefepime had similar incidence of acute kidney injury as those treated with piperacillin-tazobactam and more neurological dysfunction. We have some concerns about this study. (Source: JAMA)
Source: JAMA - February 27, 2024 Category: General Medicine Source Type: research
Review of Evaluation and Treatment of Knee Pain
To the Editor We read with great interest the Review on the evaluation and treatment of knee pain. (Source: JAMA)
Source: JAMA - February 27, 2024 Category: General Medicine Source Type: research
Use of Landiolol for Patients With Septic Shock and Organ Failure
To the Editor The use of β-blockers during septic shock aims to counter adrenergic stress and may be justified by the early reduction in deleterious effects resulting from sympathetic overactivation. Contrary to a previous study, the authors of the Study Into the Reversal of Septic Shock With Landiolol (STRESS-L) conclude that an infusion of landiolol did not reduce organ failure, and thus, the results of the study do not support its use among patients treated with norepinephrine for established septic shock. (Source: JAMA)
Source: JAMA - February 27, 2024 Category: General Medicine Source Type: research
Food and Satiety
The answer to the question, “What constitutes a proper diet?” has undergone a change from time to time in harmony with the growth of knowledge regarding nutrition. The physician has been concerned since early days with the use of food not merely to sustain life but also as a method of promoting health. Thus, Libby reminds us that the hippocratic book “On Ancient Medicine,” which ingeniously traces the origin of the medical art to the practical study of diet by man from the remotest past, suggests to the physician that advances are still to be made by continuing the study with full knowledge of what has already be e...
Source: JAMA - February 27, 2024 Category: General Medicine Source Type: research
