Use of Landiolol for Patients With Septic Shock and Organ Failure

To the Editor The use of β-blockers during septic shock aims to counter adrenergic stress and may be justified by the early reduction in deleterious effects resulting from sympathetic overactivation. Contrary to a previous study, the authors of the Study Into the Reversal of Septic Shock With Landiolol (STRESS-L) conclude that an infusion of landiolol did not reduce organ failure, and thus, the results of the study do not support its use among patients treated with norepinephrine for established septic shock.
Source: JAMA - Category: General Medicine Source Type: research