Jama
(Source: JAMA)
Source: JAMA - January 2, 2024 Category: General Medicine Source Type: research

For her seventy-third birthday, my mother
wants a bicycle. She doesn ’t mean the stationary type, as seen in sweat-glazed commercials. What she desires are thin tires, pro-level gears, and squeezable brakes. Twenty speeds at least. A bike with a basket I’ll pedal to Boston, she alliterates, which is when I wonder if it’s her illness talking (manic phases, grand iosity) and not the unpoetic woman with next-to-zero muscle. The one who totters from bed to toilet, who can’t stand without leverage. A diminished-yet-persistent person I could try harder to love. A real racing machine, she says every day this week. Who knows why she’s stuck on bikes. Maybe she s...
Source: JAMA - January 2, 2024 Category: General Medicine Source Type: research

Partial Heart Transplant in a Neonate with Irreparable Truncal Valve Dysfunction
This case report documents the first partial heart transplant in a neonate with irreparable heart valve dysfunction to deliver aortic and pulmonary valves that grow with the developing child. (Source: JAMA)
Source: JAMA - January 2, 2024 Category: General Medicine Source Type: research

Impact of Integrated Interventions on Childhood Neurodevelopment
This randomized trial assesses interventions that span preconception through early childhood compared with usual care on neurodevelopment among children at age 24 months in low- and middle-income neighborhoods in India. (Source: JAMA)
Source: JAMA - January 2, 2024 Category: General Medicine Source Type: research

Coping With the Energy Crisis
M. Therese Southgate, MD (Source: JAMA)
Source: JAMA - January 2, 2024 Category: General Medicine Source Type: research

Audio Highlights
Listen to the JAMA Editor ’s Audio Summary for an overview and discussion of the important articles appearing in this week’s issue of JAMA. (Source: JAMA)
Source: JAMA - January 2, 2024 Category: General Medicine Source Type: research

Optimizing Interventions for Early Childhood
Early childhood is a critical period for development. The estimated costs of children not reaching their full developmental potential during this period are high and persist throughout life, including lower economic productivity and poorer health. Attaining full developmental potential has been recognized as the right of every child, and investing in early childhood development is key to breaking intergenerational cycles of poverty, increasing human capital, and improving population health and well-being. Yet the most recent estimates indicate that about 43% of children younger than 5 years in low- and middle-income countr...
Source: JAMA - January 2, 2024 Category: General Medicine Source Type: research

Jama
(Source: JAMA)
Source: JAMA - December 26, 2023 Category: General Medicine Source Type: research

Blood and Hyacinths: The Human Condition in Poetry
“Browsing the Journal of Gastrointestinal Distress” might seem an odd title for a poem, but not one written to honor the acclaimed Serbian American poet Charles Simic, who died in January 2023. Simic’s poetry was colored by his early years in then-Yugoslavia amidst the specter of bloody politi cal oppression, and was also distinctly American in its belief that art could be liberating. Thus “Browsing” tells of hyacinths planted among lyrically inscribed gravestones, the first in a series of juxtapositions that suggest beauty amidst darkness. Similarly, the speaker’s fascination with the strange loveliness of the...
Source: JAMA - December 26, 2023 Category: General Medicine Source Type: research

Browsing the Journal of Gastrointestinal Distress
upon the death of Charles Simic (Source: JAMA)
Source: JAMA - December 26, 2023 Category: General Medicine Source Type: research

Hospital Adverse Events and Patient Outcomes Associated With Private Equity Acquisition
This observation study examines changes in hospital-acquired adverse events (or conditions) and hospitalization outcomes associated with private equity acquisition among Medicare beneficiaries treated at private equity –acquired hospitals compared with events and outcomes among Medicare beneficiaries treated at control hospitals. (Source: JAMA)
Source: JAMA - December 26, 2023 Category: General Medicine Source Type: research

Atrial Fibrillation Catheter Ablation and Psychological Distress —Reply
In Reply Dr Giannopoulos and colleagues suggest that our results demonstrating improved psychological distress among patients with atrial fibrillation undergoing ablation may be due to a placebo effect. They also suggest that a sham ablation procedure would be required to rule out a placebo effect. However, the study they cite to support this assertion is about the placebo effect of medical therapy (not a surgical intervention) with a brief follow-up of only 10 weeks. We prospectively randomized patients to receive either ablation or active medical therapy with 12 months of follow-up. Participants in the medical therapy gr...
Source: JAMA - December 26, 2023 Category: General Medicine Source Type: research

Extracranial-Intracranial Bypass in Patients With Symptomatic Artery Occlusion —Reply
In Reply We thank Drs Darsaut and Raymond for their comments about our randomized clinical trial involving EC-IC bypass surgery in patients with symptomatic carotid and middle cerebral artery occlusion. (Source: JAMA)
Source: JAMA - December 26, 2023 Category: General Medicine Source Type: research

Manchester Procedure vs Sacrospinous Hysteropexy for Pelvic Organ Prolapse —Reply
In Reply We appreciate the thoughtful comments of Dr Ye and colleagues and respond on behalf of the entire SAM Study Group. In the SAM study, we proved inferiority of sacrospinous hysteropexy compared with the Manchester procedure for the techniques as applied in the SAM study. We underline that a relevant step in this modification of the Manchester procedure was the extraperitoneal posterior plication with 3 or 4 sutures running through the uterosacral ligaments that were left attached to the amputated uterus. Until recently, neither the traditional technique nor modifications had been compared in large, well-performed ra...
Source: JAMA - December 26, 2023 Category: General Medicine Source Type: research

Atrial Fibrillation Catheter Ablation and Psychological Distress
To the Editor A recent study examined the effects of atrial fibrillation catheter ablation on mental health. This is a clinically relevant area of research, and the results are certainly interesting, although there is a question, in our opinion, regarding the nature of the observed associations. Treatment for depression is notorious for placebo effects, and it appears such effects may be due to activation of certain neurotransmitting pathways by the “idea” of active treatment. Research has shown that placebo-induced activation of the μ-opioid system is implicated in the formation of placebo antidepressant effects, eve...
Source: JAMA - December 26, 2023 Category: General Medicine Source Type: research