Treatment of SARS-CoV-2 Infection in US Nursing Homes
To the Editor A recent Research Letter examined COVID-19 treatment rates in US nursing homes from May 31, 2021, through December 25, 2022, and found that only 1 in 4 nursing home residents with COVID-19 had been treated with antiviral treatments and that more than 40% of nursing homes reported never administering any oral antiviral or monoclonal antibody treatment in the 19-month study window. As a practicing nursing home attending physician and medical director, I wish to elaborate on some of the barriers to treatment in nursing homes to highlight policy changes that could improve treatment rates in future pandemics. (Source: JAMA)
Source: JAMA - November 28, 2023 Category: General Medicine Source Type: research

The Foundation of Ethics, The Public Service of Professions
(Source: JAMA)
Source: JAMA - November 28, 2023 Category: General Medicine Source Type: research

Audio Highlights
Listen to the JAMA Editor ’s Audio Summary for an overview and discussion of the important articles appearing in this week’s issue of JAMA. (Source: JAMA)
Source: JAMA - November 28, 2023 Category: General Medicine Source Type: research

Immunotherapy for Nasopharyngeal Carcinoma
Due to a unique immune substrate consisting of abundant lymphocytic infiltration, high programmed death –ligand 1 (PD-L1) expression, and the presence of several immune targets (CD40, CD70, CD80, and CD86), there is a strong biological rationale for incorporating immunotherapy in the treatment of nasopharyngeal carcinoma (NPC). Nonkeratinizing histological subtypes encompass more than 95% of NPC cas es in endemic areas, and NPC is largely linked to Epstein-Barr virus (EBV) infection, providing an additional immune-prone factor through the expression of EBV antigens and CD4+/CD8+ T-cell target proteins. In this issue of J...
Source: JAMA - November 28, 2023 Category: General Medicine Source Type: research

Jama
(Source: JAMA)
Source: JAMA - November 21, 2023 Category: General Medicine Source Type: research