Palliative Telecare and Quality of Life in Patients With COPD, Heart Failure, or Interstitial Lung Disease
This randomized clinical trial compares differences in quality of life among 306 adults at high risk of death who have COPD, heart failure, or interstitial lung disease and who received nurse and social worker palliative telecare vs usual care. (Source: JAMA)
Source: JAMA - January 16, 2024 Category: General Medicine Source Type: research
Diagnosis of Autism —Reply
In Reply We appreciate Dr Cirillo ’s interest in our study, which presented clinical validation data for the measurement of social visual engagement to aid in early diagnosis and assessment of autism. Cirillo asks what constitutes expert clinician diagnosis of autism, whether the clinical trial followed criterion-standard best pra ctices for expert clinician diagnosis, and about the role of medically trained clinicians. We can reassure Cirillo on all fronts. (Source: JAMA)
Source: JAMA - January 16, 2024 Category: General Medicine Source Type: research
Amoxicillin-Clavulanate vs Amoxicillin for Pediatric Acute Sinusitis —Reply
In Reply In their Letter regarding our recent study, Dr He and colleagues note that by excluding patients who received antibiotics in the prior 30 days, participants were at lower risk of an antibiotic-resistant infection, which may have masked a benefit of amoxicillin-clavulanate. We excluded patients with recent antibiotic exposure for the following reasons: (1) to ensure a new user design, which mitigates bias; and (2) to focus on the largest group of patients with acute sinusitis because most patients do not have recent antibiotic exposure (98% in our study). The comparative risk of treatment failure with amoxicillin-c...
Source: JAMA - January 16, 2024 Category: General Medicine Source Type: research
Cannabis Use and Perinatal Health —Reply
In Reply We thank Dr Ceasar and colleagues for their Letter. We agree that it is important to underscore the potential societal and equity implications of health policy regarding cannabis use. The continued federally illegal status of cannabis along with the history of stigma and punitive measures may continue to have an effect on patients ’ trust and willingness to discuss cannabis use with clinicians. While acknowledging this context, reproductive health clinicians need to have evidence-based, objective, and nonjudgmental conversations with patients about the health effects of cannabis. The goal of our Viewpoint was to...
Source: JAMA - January 16, 2024 Category: General Medicine Source Type: research
Diagnosis of Autism
To the Editor Deficits in nonverbal communicative behaviors used for social interaction are manifested by absent, reduced, or atypical use of eye contact. The study by Jones et al is an important step toward the development of reliable diagnostic aids for autism spectrum disorders. My concern relates to the formulation of expert clinician diagnosis, which is central to the determination of the sensitivity and specificity of the eye-tracking measurement of social visual engagement for autism diagnoses. (Source: JAMA)
Source: JAMA - January 16, 2024 Category: General Medicine Source Type: research
Amoxicillin-Clavulanate vs Amoxicillin for Pediatric Acute Sinusitis
In this study, use of amoxicillin-clavulanate was associated with more frequent gastrointestinal adverse events and yeast infections. We have some concerns about this study. (Source: JAMA)
Source: JAMA - January 16, 2024 Category: General Medicine Source Type: research
Cannabis Use and Perinatal Health
To the Editor We write to JAMA as a medical anthropologist, historian of science, and obstetrician-gynecologist who read the recent Viewpoint on cannabis use and perinatal health research. We commend the authors for drawing attention to the paternal contributions to newborn health because research often overemphasizes the role of mothers to the neglect of broader familial and social contexts. (Source: JAMA)
Source: JAMA - January 16, 2024 Category: General Medicine Source Type: research
The Bedborough Trial
Dr. Havelock Ellis of London is a lawyer as well as a trained medical scientific man. He is the author and compiler of many valuable works on medicolegal topics. His papers on criminality and his studies of sociologic questions have given him a wide reputation in both this country and in Europe, and he published in 1894 a remarkable work “On Man and Woman,” which was a pioneer study on the psychologic and anthropologic differences of the sexes. This was followed in 1897 by the first volume of a series of works on the general study of the psychology of sex. This work was called “Sexual Inversion,” and was confined t...
Source: JAMA - January 16, 2024 Category: General Medicine Source Type: research
Audio Highlights
Listen to the JAMA Editor ’s Audio Summary for an overview and discussion of the important articles appearing in this week’s issue of JAMA. (Source: JAMA)
Source: JAMA - January 16, 2024 Category: General Medicine Source Type: research
A Tale of 2 Palliative Care Trials
At first glance, the 2 palliative care trials in this issue of JAMA may seem a study in contrasts. One was an outpatient intervention, the other inpatient. One included 306 participants, the other 24 065. One was an efficacy study, the other a pragmatic effectiveness study. One of the interventions added resources to expand access to palliative care, the other tried to expand access to palliative care with no additional resources. In one study the primary outcome was quality of life (QOL), in the other length of stay (LOS). In one study the primary outcome was positive, in the other it was negative. (Source: JAMA)
Source: JAMA - January 16, 2024 Category: General Medicine Source Type: research
Benefits of Breast Cancer Screening and Treatment on Mortality
Breast cancer mortality has declined precipitously in the past 5 decades, from 48 per 100 000 females in 1975 to 27 per 100 000 in 2019. This large improvement in outcomes is a testament to the development and dissemination of evidence-based strategies to improve early detection and timely treatment of breast cancer—achieved through decades of public and private investment in rese arch and research translation. However, it is challenging to quantify the relative contributions of prior investments or advances in breast cancer screening and treatment. Without such knowledge, decisions about setting future research pri...
Source: JAMA - January 16, 2024 Category: General Medicine Source Type: research
Incorrect Wording
This article was corrected online. (Source: JAMA)
Source: JAMA - January 16, 2024 Category: General Medicine Source Type: research
Revisions to Text in Results Section and Table 1
This article was corrected online. (Source: JAMA)
Source: JAMA - January 16, 2024 Category: General Medicine Source Type: research
Jama
(Source: JAMA)
Source: JAMA - January 9, 2024 Category: General Medicine Source Type: research
Review of Age-Related Macular Degeneration
This review summarizes current evidence regarding pathophysiology, risk factors, clinical presentation, diagnosis, and treatment of age-related macular degeneration. (Source: JAMA)
Source: JAMA - January 9, 2024 Category: General Medicine Source Type: research
