Potential effects of gingerol topical application on components of the innate immunity in lactating goat mammary glands
Innate Immun. 2023 Aug 22:17534259231191252. doi: 10.1177/17534259231191252. Online ahead of print.ABSTRACTIn the mammary glands, production of antimicrobial components and formation of less-permeable tight junctions (TJs) are important for safe milk production. Previously, we reported that local heat treatment of udders using disposable heating pad enhances the components of innate immunity in lactating goat mammary glands. Gingerol is a polyphenol present in ginger that can induce heat-like effects. However, oral administration of polyphenols causes a decrease in biological activity through conjugation and metabolic conv...
Source: Innate Immunity - August 22, 2023 Category: Allergy & Immunology Authors: Yusaku Tsugami Takahiro Nii Ken Kobayashi Naoki Isobe Source Type: research
Potential effects of gingerol topical application on components of the innate immunity in lactating goat mammary glands
Innate Immun. 2023 Aug 22:17534259231191252. doi: 10.1177/17534259231191252. Online ahead of print.ABSTRACTIn the mammary glands, production of antimicrobial components and formation of less-permeable tight junctions (TJs) are important for safe milk production. Previously, we reported that local heat treatment of udders using disposable heating pad enhances the components of innate immunity in lactating goat mammary glands. Gingerol is a polyphenol present in ginger that can induce heat-like effects. However, oral administration of polyphenols causes a decrease in biological activity through conjugation and metabolic conv...
Source: Innate Immunity - August 22, 2023 Category: Allergy & Immunology Authors: Yusaku Tsugami Takahiro Nii Ken Kobayashi Naoki Isobe Source Type: research
Potential effects of gingerol topical application on components of the innate immunity in lactating goat mammary glands
Innate Immun. 2023 Aug 22:17534259231191252. doi: 10.1177/17534259231191252. Online ahead of print.ABSTRACTIn the mammary glands, production of antimicrobial components and formation of less-permeable tight junctions (TJs) are important for safe milk production. Previously, we reported that local heat treatment of udders using disposable heating pad enhances the components of innate immunity in lactating goat mammary glands. Gingerol is a polyphenol present in ginger that can induce heat-like effects. However, oral administration of polyphenols causes a decrease in biological activity through conjugation and metabolic conv...
Source: Innate Immunity - August 22, 2023 Category: Allergy & Immunology Authors: Yusaku Tsugami Takahiro Nii Ken Kobayashi Naoki Isobe Source Type: research
Potential effects of gingerol topical application on components of the innate immunity in lactating goat mammary glands
Innate Immun. 2023 Aug 22:17534259231191252. doi: 10.1177/17534259231191252. Online ahead of print.ABSTRACTIn the mammary glands, production of antimicrobial components and formation of less-permeable tight junctions (TJs) are important for safe milk production. Previously, we reported that local heat treatment of udders using disposable heating pad enhances the components of innate immunity in lactating goat mammary glands. Gingerol is a polyphenol present in ginger that can induce heat-like effects. However, oral administration of polyphenols causes a decrease in biological activity through conjugation and metabolic conv...
Source: Innate Immunity - August 22, 2023 Category: Allergy & Immunology Authors: Yusaku Tsugami Takahiro Nii Ken Kobayashi Naoki Isobe Source Type: research
Potential effects of gingerol topical application on components of the innate immunity in lactating goat mammary glands
Innate Immun. 2023 Aug 22:17534259231191252. doi: 10.1177/17534259231191252. Online ahead of print.ABSTRACTIn the mammary glands, production of antimicrobial components and formation of less-permeable tight junctions (TJs) are important for safe milk production. Previously, we reported that local heat treatment of udders using disposable heating pad enhances the components of innate immunity in lactating goat mammary glands. Gingerol is a polyphenol present in ginger that can induce heat-like effects. However, oral administration of polyphenols causes a decrease in biological activity through conjugation and metabolic conv...
Source: Innate Immunity - August 22, 2023 Category: Allergy & Immunology Authors: Yusaku Tsugami Takahiro Nii Ken Kobayashi Naoki Isobe Source Type: research
Potential effects of gingerol topical application on components of the innate immunity in lactating goat mammary glands
Innate Immun. 2023 Aug 22:17534259231191252. doi: 10.1177/17534259231191252. Online ahead of print.ABSTRACTIn the mammary glands, production of antimicrobial components and formation of less-permeable tight junctions (TJs) are important for safe milk production. Previously, we reported that local heat treatment of udders using disposable heating pad enhances the components of innate immunity in lactating goat mammary glands. Gingerol is a polyphenol present in ginger that can induce heat-like effects. However, oral administration of polyphenols causes a decrease in biological activity through conjugation and metabolic conv...
Source: Innate Immunity - August 22, 2023 Category: Allergy & Immunology Authors: Yusaku Tsugami Takahiro Nii Ken Kobayashi Naoki Isobe Source Type: research
Potential effects of gingerol topical application on components of the innate immunity in lactating goat mammary glands
Innate Immun. 2023 Aug 22:17534259231191252. doi: 10.1177/17534259231191252. Online ahead of print.ABSTRACTIn the mammary glands, production of antimicrobial components and formation of less-permeable tight junctions (TJs) are important for safe milk production. Previously, we reported that local heat treatment of udders using disposable heating pad enhances the components of innate immunity in lactating goat mammary glands. Gingerol is a polyphenol present in ginger that can induce heat-like effects. However, oral administration of polyphenols causes a decrease in biological activity through conjugation and metabolic conv...
Source: Innate Immunity - August 22, 2023 Category: Allergy & Immunology Authors: Yusaku Tsugami Takahiro Nii Ken Kobayashi Naoki Isobe Source Type: research
Potential effects of gingerol topical application on components of the innate immunity in lactating goat mammary glands
Innate Immun. 2023 Aug 22:17534259231191252. doi: 10.1177/17534259231191252. Online ahead of print.ABSTRACTIn the mammary glands, production of antimicrobial components and formation of less-permeable tight junctions (TJs) are important for safe milk production. Previously, we reported that local heat treatment of udders using disposable heating pad enhances the components of innate immunity in lactating goat mammary glands. Gingerol is a polyphenol present in ginger that can induce heat-like effects. However, oral administration of polyphenols causes a decrease in biological activity through conjugation and metabolic conv...
Source: Innate Immunity - August 22, 2023 Category: Allergy & Immunology Authors: Yusaku Tsugami Takahiro Nii Ken Kobayashi Naoki Isobe Source Type: research
Potential effects of gingerol topical application on components of the innate immunity in lactating goat mammary glands
Innate Immun. 2023 Aug 22:17534259231191252. doi: 10.1177/17534259231191252. Online ahead of print.ABSTRACTIn the mammary glands, production of antimicrobial components and formation of less-permeable tight junctions (TJs) are important for safe milk production. Previously, we reported that local heat treatment of udders using disposable heating pad enhances the components of innate immunity in lactating goat mammary glands. Gingerol is a polyphenol present in ginger that can induce heat-like effects. However, oral administration of polyphenols causes a decrease in biological activity through conjugation and metabolic conv...
Source: Innate Immunity - August 22, 2023 Category: Allergy & Immunology Authors: Yusaku Tsugami Takahiro Nii Ken Kobayashi Naoki Isobe Source Type: research
Potential effects of gingerol topical application on components of the innate immunity in lactating goat mammary glands
Innate Immun. 2023 Aug 22:17534259231191252. doi: 10.1177/17534259231191252. Online ahead of print.ABSTRACTIn the mammary glands, production of antimicrobial components and formation of less-permeable tight junctions (TJs) are important for safe milk production. Previously, we reported that local heat treatment of udders using disposable heating pad enhances the components of innate immunity in lactating goat mammary glands. Gingerol is a polyphenol present in ginger that can induce heat-like effects. However, oral administration of polyphenols causes a decrease in biological activity through conjugation and metabolic conv...
Source: Innate Immunity - August 22, 2023 Category: Allergy & Immunology Authors: Yusaku Tsugami Takahiro Nii Ken Kobayashi Naoki Isobe Source Type: research
Potential effects of gingerol topical application on components of the innate immunity in lactating goat mammary glands
Innate Immun. 2023 Aug 22:17534259231191252. doi: 10.1177/17534259231191252. Online ahead of print.ABSTRACTIn the mammary glands, production of antimicrobial components and formation of less-permeable tight junctions (TJs) are important for safe milk production. Previously, we reported that local heat treatment of udders using disposable heating pad enhances the components of innate immunity in lactating goat mammary glands. Gingerol is a polyphenol present in ginger that can induce heat-like effects. However, oral administration of polyphenols causes a decrease in biological activity through conjugation and metabolic conv...
Source: Innate Immunity - August 22, 2023 Category: Allergy & Immunology Authors: Yusaku Tsugami Takahiro Nii Ken Kobayashi Naoki Isobe Source Type: research
Potential effects of gingerol topical application on components of the innate immunity in lactating goat mammary glands
Innate Immun. 2023 Aug 22:17534259231191252. doi: 10.1177/17534259231191252. Online ahead of print.ABSTRACTIn the mammary glands, production of antimicrobial components and formation of less-permeable tight junctions (TJs) are important for safe milk production. Previously, we reported that local heat treatment of udders using disposable heating pad enhances the components of innate immunity in lactating goat mammary glands. Gingerol is a polyphenol present in ginger that can induce heat-like effects. However, oral administration of polyphenols causes a decrease in biological activity through conjugation and metabolic conv...
Source: Innate Immunity - August 22, 2023 Category: Allergy & Immunology Authors: Yusaku Tsugami Takahiro Nii Ken Kobayashi Naoki Isobe Source Type: research
Potential effects of gingerol topical application on components of the innate immunity in lactating goat mammary glands
Innate Immun. 2023 Aug 22:17534259231191252. doi: 10.1177/17534259231191252. Online ahead of print.ABSTRACTIn the mammary glands, production of antimicrobial components and formation of less-permeable tight junctions (TJs) are important for safe milk production. Previously, we reported that local heat treatment of udders using disposable heating pad enhances the components of innate immunity in lactating goat mammary glands. Gingerol is a polyphenol present in ginger that can induce heat-like effects. However, oral administration of polyphenols causes a decrease in biological activity through conjugation and metabolic conv...
Source: Innate Immunity - August 22, 2023 Category: Allergy & Immunology Authors: Yusaku Tsugami Takahiro Nii Ken Kobayashi Naoki Isobe Source Type: research
Potential effects of gingerol topical application on components of the innate immunity in lactating goat mammary glands
Innate Immun. 2023 Aug 22:17534259231191252. doi: 10.1177/17534259231191252. Online ahead of print.ABSTRACTIn the mammary glands, production of antimicrobial components and formation of less-permeable tight junctions (TJs) are important for safe milk production. Previously, we reported that local heat treatment of udders using disposable heating pad enhances the components of innate immunity in lactating goat mammary glands. Gingerol is a polyphenol present in ginger that can induce heat-like effects. However, oral administration of polyphenols causes a decrease in biological activity through conjugation and metabolic conv...
Source: Innate Immunity - August 22, 2023 Category: Allergy & Immunology Authors: Yusaku Tsugami Takahiro Nii Ken Kobayashi Naoki Isobe Source Type: research
Dietary fat differentially modulates the response of bone marrow-derived macrophages to TLR4 and NOD2 agonists
In this study, we subjected WT mice to a control diet or to HFDs comprised of various ratios of unsaturated to saturated fats and determined the macrophage response to TLR4 and NOD2 agonists. A HFD with equal ratios of saturated and unsaturated fats enhanced subsequent responsiveness of macrophages to LPS but not to MDP. However, a high-unsaturated fat diet (HUFD) or a high-saturated fat diet (HSFD) both decreased the responsiveness to NOD2 agonists compared to that observed in control diet (CD) fed mice. These data suggest that dietary fatty acid composition can influence the subsequent macrophage responsiveness to bacter...
Source: Innate Immunity - August 7, 2023 Category: Allergy & Immunology Authors: Michael G Shehat Madelyn H Miller Ashley N Calder Timothy A Gilbertson Justine T Tigno-Aranjuez Source Type: research
