Role of neutrophils in different stages of atherosclerosis
Innate Immun. 2023 Jul 25:17534259231189195. doi: 10.1177/17534259231189195. Online ahead of print.ABSTRACTNeutrophils constitute the first line of defense in human immunity and can be attracted to inflamed and infected sites by various chemokines. As essential players in immune processes, neutrophils theoretically play integral roles in the course of chronic inflammation-induced atherosclerosis. However, because neutrophils are rarely found in atherosclerotic lesions, their involvement in the pathophysiological progression of atherosclerosis has been largely underestimated or ignored. Recent research has revealed convinci...
Source: Innate Immunity - July 26, 2023 Category: Allergy & Immunology Authors: Xiaojing Zhang Zhanfang Kang Dazhong Yin Jun Gao Source Type: research

Role of neutrophils in different stages of atherosclerosis
Innate Immun. 2023 Jul 25:17534259231189195. doi: 10.1177/17534259231189195. Online ahead of print.ABSTRACTNeutrophils constitute the first line of defense in human immunity and can be attracted to inflamed and infected sites by various chemokines. As essential players in immune processes, neutrophils theoretically play integral roles in the course of chronic inflammation-induced atherosclerosis. However, because neutrophils are rarely found in atherosclerotic lesions, their involvement in the pathophysiological progression of atherosclerosis has been largely underestimated or ignored. Recent research has revealed convinci...
Source: Innate Immunity - July 26, 2023 Category: Allergy & Immunology Authors: Xiaojing Zhang Zhanfang Kang Dazhong Yin Jun Gao Source Type: research

Role of neutrophils in different stages of atherosclerosis
Innate Immun. 2023 Jul 25:17534259231189195. doi: 10.1177/17534259231189195. Online ahead of print.ABSTRACTNeutrophils constitute the first line of defense in human immunity and can be attracted to inflamed and infected sites by various chemokines. As essential players in immune processes, neutrophils theoretically play integral roles in the course of chronic inflammation-induced atherosclerosis. However, because neutrophils are rarely found in atherosclerotic lesions, their involvement in the pathophysiological progression of atherosclerosis has been largely underestimated or ignored. Recent research has revealed convinci...
Source: Innate Immunity - July 26, 2023 Category: Allergy & Immunology Authors: Xiaojing Zhang Zhanfang Kang Dazhong Yin Jun Gao Source Type: research

Role of neutrophils in different stages of atherosclerosis
Innate Immun. 2023 Jul 25:17534259231189195. doi: 10.1177/17534259231189195. Online ahead of print.ABSTRACTNeutrophils constitute the first line of defense in human immunity and can be attracted to inflamed and infected sites by various chemokines. As essential players in immune processes, neutrophils theoretically play integral roles in the course of chronic inflammation-induced atherosclerosis. However, because neutrophils are rarely found in atherosclerotic lesions, their involvement in the pathophysiological progression of atherosclerosis has been largely underestimated or ignored. Recent research has revealed convinci...
Source: Innate Immunity - July 26, 2023 Category: Allergy & Immunology Authors: Xiaojing Zhang Zhanfang Kang Dazhong Yin Jun Gao Source Type: research

Role of neutrophils in different stages of atherosclerosis
Innate Immun. 2023 Jul 25:17534259231189195. doi: 10.1177/17534259231189195. Online ahead of print.ABSTRACTNeutrophils constitute the first line of defense in human immunity and can be attracted to inflamed and infected sites by various chemokines. As essential players in immune processes, neutrophils theoretically play integral roles in the course of chronic inflammation-induced atherosclerosis. However, because neutrophils are rarely found in atherosclerotic lesions, their involvement in the pathophysiological progression of atherosclerosis has been largely underestimated or ignored. Recent research has revealed convinci...
Source: Innate Immunity - July 26, 2023 Category: Allergy & Immunology Authors: Xiaojing Zhang Zhanfang Kang Dazhong Yin Jun Gao Source Type: research

Killer cell immunoglobulin-like receptor (KIR) genes and their HLA ligands in a Brazilian population
This study aimed to investigate the distribution of KIR genes and HLA ligands in a population from Campinas, southeastern Brazil (n = 292), and to compare their results with other populations. A comprehensive analysis of population-specific genes, genotype, and haplotype frequencies of KIR may facilitate a better understanding of their evolution and role in immunity. The genotyping of 16 KIR genes and HLA class I alleles was performed by the reverse sequence-specific oligonucleotide methodology using the Luminex platform (One Lambda, Inc., Canoga Park, CA). The framework genes were present in all individuals, with the most...
Source: Innate Immunity - June 23, 2023 Category: Allergy & Immunology Authors: Daniela Maira Cardozo Amanda Vansan Marangon Fernando Guimar ães Silvia Marques Sofia Lieber M árcia Delamain Francisco Aranha Jeane Eliete Laguila Visentainer C ármino Antonio de Souza Source Type: research

Killer cell immunoglobulin-like receptor (KIR) genes and their HLA ligands in a Brazilian population
This study aimed to investigate the distribution of KIR genes and HLA ligands in a population from Campinas, southeastern Brazil (n = 292), and to compare their results with other populations. A comprehensive analysis of population-specific genes, genotype, and haplotype frequencies of KIR may facilitate a better understanding of their evolution and role in immunity. The genotyping of 16 KIR genes and HLA class I alleles was performed by the reverse sequence-specific oligonucleotide methodology using the Luminex platform (One Lambda, Inc., Canoga Park, CA). The framework genes were present in all individuals, with the most...
Source: Innate Immunity - June 23, 2023 Category: Allergy & Immunology Authors: Daniela Maira Cardozo Amanda Vansan Marangon Fernando Guimar ães Silvia Marques Sofia Lieber M árcia Delamain Francisco Aranha Jeane Eliete Laguila Visentainer C ármino Antonio de Souza Source Type: research

Killer cell immunoglobulin-like receptor (KIR) genes and their HLA ligands in a Brazilian population
This study aimed to investigate the distribution of KIR genes and HLA ligands in a population from Campinas, southeastern Brazil (n = 292), and to compare their results with other populations. A comprehensive analysis of population-specific genes, genotype, and haplotype frequencies of KIR may facilitate a better understanding of their evolution and role in immunity. The genotyping of 16 KIR genes and HLA class I alleles was performed by the reverse sequence-specific oligonucleotide methodology using the Luminex platform (One Lambda, Inc., Canoga Park, CA). The framework genes were present in all individuals, with the most...
Source: Innate Immunity - June 23, 2023 Category: Allergy & Immunology Authors: Daniela Maira Cardozo Amanda Vansan Marangon Fernando Guimar ães Silvia Marques Sofia Lieber M árcia Delamain Francisco Aranha Jeane Eliete Laguila Visentainer C ármino Antonio de Souza Source Type: research

Killer cell immunoglobulin-like receptor (KIR) genes and their HLA ligands in a Brazilian population
This study aimed to investigate the distribution of KIR genes and HLA ligands in a population from Campinas, southeastern Brazil (n = 292), and to compare their results with other populations. A comprehensive analysis of population-specific genes, genotype, and haplotype frequencies of KIR may facilitate a better understanding of their evolution and role in immunity. The genotyping of 16 KIR genes and HLA class I alleles was performed by the reverse sequence-specific oligonucleotide methodology using the Luminex platform (One Lambda, Inc., Canoga Park, CA). The framework genes were present in all individuals, with the most...
Source: Innate Immunity - June 23, 2023 Category: Allergy & Immunology Authors: Daniela Maira Cardozo Amanda Vansan Marangon Fernando Guimar ães Silvia Marques Sofia Lieber M árcia Delamain Francisco Aranha Jeane Eliete Laguila Visentainer C ármino Antonio de Souza Source Type: research

Killer cell immunoglobulin-like receptor (KIR) genes and their HLA ligands in a Brazilian population
This study aimed to investigate the distribution of KIR genes and HLA ligands in a population from Campinas, southeastern Brazil (n = 292), and to compare their results with other populations. A comprehensive analysis of population-specific genes, genotype, and haplotype frequencies of KIR may facilitate a better understanding of their evolution and role in immunity. The genotyping of 16 KIR genes and HLA class I alleles was performed by the reverse sequence-specific oligonucleotide methodology using the Luminex platform (One Lambda, Inc., Canoga Park, CA). The framework genes were present in all individuals, with the most...
Source: Innate Immunity - June 23, 2023 Category: Allergy & Immunology Authors: Daniela Maira Cardozo Amanda Vansan Marangon Fernando Guimar ães Silvia Marques Sofia Lieber M árcia Delamain Francisco Aranha Jeane Eliete Laguila Visentainer C ármino Antonio de Souza Source Type: research

Killer cell immunoglobulin-like receptor (KIR) genes and their HLA ligands in a Brazilian population
This study aimed to investigate the distribution of KIR genes and HLA ligands in a population from Campinas, southeastern Brazil (n = 292), and to compare their results with other populations. A comprehensive analysis of population-specific genes, genotype, and haplotype frequencies of KIR may facilitate a better understanding of their evolution and role in immunity. The genotyping of 16 KIR genes and HLA class I alleles was performed by the reverse sequence-specific oligonucleotide methodology using the Luminex platform (One Lambda, Inc., Canoga Park, CA). The framework genes were present in all individuals, with the most...
Source: Innate Immunity - June 23, 2023 Category: Allergy & Immunology Authors: Daniela Maira Cardozo Amanda Vansan Marangon Fernando Guimar ães Silvia Marques Sofia Lieber M árcia Delamain Francisco Aranha Jeane Eliete Laguila Visentainer C ármino Antonio de Souza Source Type: research

Killer cell immunoglobulin-like receptor (KIR) genes and their HLA ligands in a Brazilian population
This study aimed to investigate the distribution of KIR genes and HLA ligands in a population from Campinas, southeastern Brazil (n = 292), and to compare their results with other populations. A comprehensive analysis of population-specific genes, genotype, and haplotype frequencies of KIR may facilitate a better understanding of their evolution and role in immunity. The genotyping of 16 KIR genes and HLA class I alleles was performed by the reverse sequence-specific oligonucleotide methodology using the Luminex platform (One Lambda, Inc., Canoga Park, CA). The framework genes were present in all individuals, with the most...
Source: Innate Immunity - June 23, 2023 Category: Allergy & Immunology Authors: Daniela Maira Cardozo Amanda Vansan Marangon Fernando Guimar ães Silvia Marques Sofia Lieber M árcia Delamain Francisco Aranha Jeane Eliete Laguila Visentainer C ármino Antonio de Souza Source Type: research

Killer cell immunoglobulin-like receptor (KIR) genes and their HLA ligands in a Brazilian population
This study aimed to investigate the distribution of KIR genes and HLA ligands in a population from Campinas, southeastern Brazil (n = 292), and to compare their results with other populations. A comprehensive analysis of population-specific genes, genotype, and haplotype frequencies of KIR may facilitate a better understanding of their evolution and role in immunity. The genotyping of 16 KIR genes and HLA class I alleles was performed by the reverse sequence-specific oligonucleotide methodology using the Luminex platform (One Lambda, Inc., Canoga Park, CA). The framework genes were present in all individuals, with the most...
Source: Innate Immunity - June 23, 2023 Category: Allergy & Immunology Authors: Daniela Maira Cardozo Amanda Vansan Marangon Fernando Guimar ães Silvia Marques Sofia Lieber M árcia Delamain Francisco Aranha Jeane Eliete Laguila Visentainer C ármino Antonio de Souza Source Type: research

Killer cell immunoglobulin-like receptor (KIR) genes and their HLA ligands in a Brazilian population
This study aimed to investigate the distribution of KIR genes and HLA ligands in a population from Campinas, southeastern Brazil (n = 292), and to compare their results with other populations. A comprehensive analysis of population-specific genes, genotype, and haplotype frequencies of KIR may facilitate a better understanding of their evolution and role in immunity. The genotyping of 16 KIR genes and HLA class I alleles was performed by the reverse sequence-specific oligonucleotide methodology using the Luminex platform (One Lambda, Inc., Canoga Park, CA). The framework genes were present in all individuals, with the most...
Source: Innate Immunity - June 23, 2023 Category: Allergy & Immunology Authors: Daniela Maira Cardozo Amanda Vansan Marangon Fernando Guimar ães Silvia Marques Sofia Lieber M árcia Delamain Francisco Aranha Jeane Eliete Laguila Visentainer C ármino Antonio de Souza Source Type: research

Killer cell immunoglobulin-like receptor (KIR) genes and their HLA ligands in a Brazilian population
This study aimed to investigate the distribution of KIR genes and HLA ligands in a population from Campinas, southeastern Brazil (n = 292), and to compare their results with other populations. A comprehensive analysis of population-specific genes, genotype, and haplotype frequencies of KIR may facilitate a better understanding of their evolution and role in immunity. The genotyping of 16 KIR genes and HLA class I alleles was performed by the reverse sequence-specific oligonucleotide methodology using the Luminex platform (One Lambda, Inc., Canoga Park, CA). The framework genes were present in all individuals, with the most...
Source: Innate Immunity - June 23, 2023 Category: Allergy & Immunology Authors: Daniela Maira Cardozo Amanda Vansan Marangon Fernando Guimar ães Silvia Marques Sofia Lieber M árcia Delamain Francisco Aranha Jeane Eliete Laguila Visentainer C ármino Antonio de Souza Source Type: research