New Insights into Immune Cells and Immunotherapy for Thyroid Cancer
This article focuses on the genomic characteristics, tumor-associated immune cell infiltration and immune checkpoint expression of different subtypes of TC patients to provide guidance for immunotherapy.PMID:37846977 | DOI:10.1080/08820139.2023.2268656 (Source: Immunological Investigations)
Source: Immunological Investigations - October 17, 2023 Category: Allergy & Immunology Authors: Yujia Tao Peng Li Chao Feng Yuan Cao Source Type: research
Regulatory T Cell Inhibition by P60 Combined with Adenoviral AFP Transduced Dendritic Cells for Immunotherapy of Hepatocellular Carcinoma
CONCLUSION: In this study, we showed that vaccination with alpha-fetoprotein-expressing dendritic cells in combination with a specific inhibition of regulatory T-cells by using P60 leads to synergistic tumor inhibition and prolonged survival. This emphasizes the importance of regulatory T-cells inhibition for obtaining an effective antitumoral immune response in hepatocellular carcinoma.PMID:37846958 | DOI:10.1080/08820139.2023.2261980 (Source: Immunological Investigations)
Source: Immunological Investigations - October 17, 2023 Category: Allergy & Immunology Authors: Farsaneh Sadeghlar Julia Seelemann Annabelle Vogt Christian M öhring Taotao Zhou Robert Mahn Miroslaw Kornek Veronika Lukacs-Kornek Noelia Casares Juan Jos é Lasarte Pablo Sarobe Cornelius van Beekum Hanno Matthaei Steffen Manekeller J örg Kalff Ingo G Source Type: research
New Insights into Immune Cells and Immunotherapy for Thyroid Cancer
This article focuses on the genomic characteristics, tumor-associated immune cell infiltration and immune checkpoint expression of different subtypes of TC patients to provide guidance for immunotherapy.PMID:37846977 | DOI:10.1080/08820139.2023.2268656 (Source: Immunological Investigations)
Source: Immunological Investigations - October 17, 2023 Category: Allergy & Immunology Authors: Yujia Tao Peng Li Chao Feng Yuan Cao Source Type: research
Regulatory T Cell Inhibition by P60 Combined with Adenoviral AFP Transduced Dendritic Cells for Immunotherapy of Hepatocellular Carcinoma
CONCLUSION: In this study, we showed that vaccination with alpha-fetoprotein-expressing dendritic cells in combination with a specific inhibition of regulatory T-cells by using P60 leads to synergistic tumor inhibition and prolonged survival. This emphasizes the importance of regulatory T-cells inhibition for obtaining an effective antitumoral immune response in hepatocellular carcinoma.PMID:37846958 | DOI:10.1080/08820139.2023.2261980 (Source: Immunological Investigations)
Source: Immunological Investigations - October 17, 2023 Category: Allergy & Immunology Authors: Farsaneh Sadeghlar Julia Seelemann Annabelle Vogt Christian M öhring Taotao Zhou Robert Mahn Miroslaw Kornek Veronika Lukacs-Kornek Noelia Casares Juan Jos é Lasarte Pablo Sarobe Cornelius van Beekum Hanno Matthaei Steffen Manekeller J örg Kalff Ingo G Source Type: research
New Insights into Immune Cells and Immunotherapy for Thyroid Cancer
This article focuses on the genomic characteristics, tumor-associated immune cell infiltration and immune checkpoint expression of different subtypes of TC patients to provide guidance for immunotherapy.PMID:37846977 | DOI:10.1080/08820139.2023.2268656 (Source: Immunological Investigations)
Source: Immunological Investigations - October 17, 2023 Category: Allergy & Immunology Authors: Yujia Tao Peng Li Chao Feng Yuan Cao Source Type: research
Regulatory T Cell Inhibition by P60 Combined with Adenoviral AFP Transduced Dendritic Cells for Immunotherapy of Hepatocellular Carcinoma
CONCLUSION: In this study, we showed that vaccination with alpha-fetoprotein-expressing dendritic cells in combination with a specific inhibition of regulatory T-cells by using P60 leads to synergistic tumor inhibition and prolonged survival. This emphasizes the importance of regulatory T-cells inhibition for obtaining an effective antitumoral immune response in hepatocellular carcinoma.PMID:37846958 | DOI:10.1080/08820139.2023.2261980 (Source: Immunological Investigations)
Source: Immunological Investigations - October 17, 2023 Category: Allergy & Immunology Authors: Farsaneh Sadeghlar Julia Seelemann Annabelle Vogt Christian M öhring Taotao Zhou Robert Mahn Miroslaw Kornek Veronika Lukacs-Kornek Noelia Casares Juan Jos é Lasarte Pablo Sarobe Cornelius van Beekum Hanno Matthaei Steffen Manekeller J örg Kalff Ingo G Source Type: research
New Insights into Immune Cells and Immunotherapy for Thyroid Cancer
This article focuses on the genomic characteristics, tumor-associated immune cell infiltration and immune checkpoint expression of different subtypes of TC patients to provide guidance for immunotherapy.PMID:37846977 | DOI:10.1080/08820139.2023.2268656 (Source: Immunological Investigations)
Source: Immunological Investigations - October 17, 2023 Category: Allergy & Immunology Authors: Yujia Tao Peng Li Chao Feng Yuan Cao Source Type: research
CAR-T Therapy Targets Extra Domain B of Fibronectin Positive Solid Tumor Cells
CONCLUSION: APT0 CAR-T and CGS2 CAR-T cells are two new CAR-Ts targeting EDB-FN. Both CAR-T cells can successfully identify and specifically kill various EDB-FN-positive solid tumor cells with potential clinical applications.PMID:37815216 | DOI:10.1080/08820139.2023.2264332 (Source: Immunological Investigations)
Source: Immunological Investigations - October 10, 2023 Category: Allergy & Immunology Authors: Jie Tang Nan Liu Yongjie Zhu Yi Li Xudong Zhao Source Type: research
Immunological Assessment of Recent Immunotherapy for Colorectal Cancer
Immunol Invest. 2023 Oct 9:1-31. doi: 10.1080/08820139.2023.2264906. Online ahead of print.ABSTRACTColorectal cancer (CRC) is the third most prevalent malignancy with increased incidence and mortality rates worldwide. Traditional treatment approaches have attempted to efficiently target CRC; however, they have failed in most cases, owing to the cytotoxicity and non-specificity of these therapies. Therefore, it is essential to develop an effective alternative therapy to improve the clinical outcomes in heterogeneous CRC cases. Immunotherapy has transformed cancer treatment with remarkable efficacy and overcomes the limitati...
Source: Immunological Investigations - October 9, 2023 Category: Allergy & Immunology Authors: Subhadeep Das Diptikanta Acharya Source Type: research
