A Crosstalk Between Castration-Resistant Prostate Cancer Cells, M2 Macrophages, and NK Cells: Role of the ATM-PI3K/AKT-PD-L1 Pathway
In conclusion, it could be demonstrated that inhibiting ATM increased the susceptibility of CRPC to NK cell inhibitors by dampening the CXCL12 and PI3K/AKT-PD-L1 pathways, thereby offering a novel and individualized treatment protocol for treating CRPC.PMID:37732622 | DOI:10.1080/08820139.2023.2258930 (Source: Immunological Investigations)
Source: Immunological Investigations - September 21, 2023 Category: Allergy & Immunology Authors: Hongliang Jin Jin Zhu Rui Xuan Yibin Zhou Boxin Xue Dongrong Yang Jie Gao Yachen Zang Lijun Xu Source Type: research
EGR-1 Contributes to Pulmonary Edema by Regulating the Epithelial Sodium Channel in Lipopolysaccharide-Induced Acute Lung Injury
In conclusion, our study demonstrated that EGR-1 could promote pulmonary edema by downregulating ENaC-α at the transcriptional level in ALI. Our study provides a new potential therapeutic strategy for treatment of ALI.PMID:37732637 | DOI:10.1080/08820139.2023.2256778 (Source: Immunological Investigations)
Source: Immunological Investigations - September 21, 2023 Category: Allergy & Immunology Authors: Song Wang Jing Ma Xin Li Xinmiao Xian Guikun Tan Hongwei Cai Bingwu Yang Anqi Zhang Jianran Guo Guohao Gu Zhen Meng Bo Fu Source Type: research
A Crosstalk Between Castration-Resistant Prostate Cancer Cells, M2 Macrophages, and NK Cells: Role of the ATM-PI3K/AKT-PD-L1 Pathway
In conclusion, it could be demonstrated that inhibiting ATM increased the susceptibility of CRPC to NK cell inhibitors by dampening the CXCL12 and PI3K/AKT-PD-L1 pathways, thereby offering a novel and individualized treatment protocol for treating CRPC.PMID:37732622 | DOI:10.1080/08820139.2023.2258930 (Source: Immunological Investigations)
Source: Immunological Investigations - September 21, 2023 Category: Allergy & Immunology Authors: Hongliang Jin Jin Zhu Rui Xuan Yibin Zhou Boxin Xue Dongrong Yang Jie Gao Yachen Zang Lijun Xu Source Type: research
EGR-1 Contributes to Pulmonary Edema by Regulating the Epithelial Sodium Channel in Lipopolysaccharide-Induced Acute Lung Injury
In conclusion, our study demonstrated that EGR-1 could promote pulmonary edema by downregulating ENaC-α at the transcriptional level in ALI. Our study provides a new potential therapeutic strategy for treatment of ALI.PMID:37732637 | DOI:10.1080/08820139.2023.2256778 (Source: Immunological Investigations)
Source: Immunological Investigations - September 21, 2023 Category: Allergy & Immunology Authors: Song Wang Jing Ma Xin Li Xinmiao Xian Guikun Tan Hongwei Cai Bingwu Yang Anqi Zhang Jianran Guo Guohao Gu Zhen Meng Bo Fu Source Type: research
A Crosstalk Between Castration-Resistant Prostate Cancer Cells, M2 Macrophages, and NK Cells: Role of the ATM-PI3K/AKT-PD-L1 Pathway
In conclusion, it could be demonstrated that inhibiting ATM increased the susceptibility of CRPC to NK cell inhibitors by dampening the CXCL12 and PI3K/AKT-PD-L1 pathways, thereby offering a novel and individualized treatment protocol for treating CRPC.PMID:37732622 | DOI:10.1080/08820139.2023.2258930 (Source: Immunological Investigations)
Source: Immunological Investigations - September 21, 2023 Category: Allergy & Immunology Authors: Hongliang Jin Jin Zhu Rui Xuan Yibin Zhou Boxin Xue Dongrong Yang Jie Gao Yachen Zang Lijun Xu Source Type: research
EGR-1 Contributes to Pulmonary Edema by Regulating the Epithelial Sodium Channel in Lipopolysaccharide-Induced Acute Lung Injury
In conclusion, our study demonstrated that EGR-1 could promote pulmonary edema by downregulating ENaC-α at the transcriptional level in ALI. Our study provides a new potential therapeutic strategy for treatment of ALI.PMID:37732637 | DOI:10.1080/08820139.2023.2256778 (Source: Immunological Investigations)
Source: Immunological Investigations - September 21, 2023 Category: Allergy & Immunology Authors: Song Wang Jing Ma Xin Li Xinmiao Xian Guikun Tan Hongwei Cai Bingwu Yang Anqi Zhang Jianran Guo Guohao Gu Zhen Meng Bo Fu Source Type: research
A Crosstalk Between Castration-Resistant Prostate Cancer Cells, M2 Macrophages, and NK Cells: Role of the ATM-PI3K/AKT-PD-L1 Pathway
In conclusion, it could be demonstrated that inhibiting ATM increased the susceptibility of CRPC to NK cell inhibitors by dampening the CXCL12 and PI3K/AKT-PD-L1 pathways, thereby offering a novel and individualized treatment protocol for treating CRPC.PMID:37732622 | DOI:10.1080/08820139.2023.2258930 (Source: Immunological Investigations)
Source: Immunological Investigations - September 21, 2023 Category: Allergy & Immunology Authors: Hongliang Jin Jin Zhu Rui Xuan Yibin Zhou Boxin Xue Dongrong Yang Jie Gao Yachen Zang Lijun Xu Source Type: research
EGR-1 Contributes to Pulmonary Edema by Regulating the Epithelial Sodium Channel in Lipopolysaccharide-Induced Acute Lung Injury
In conclusion, our study demonstrated that EGR-1 could promote pulmonary edema by downregulating ENaC-α at the transcriptional level in ALI. Our study provides a new potential therapeutic strategy for treatment of ALI.PMID:37732637 | DOI:10.1080/08820139.2023.2256778 (Source: Immunological Investigations)
Source: Immunological Investigations - September 21, 2023 Category: Allergy & Immunology Authors: Song Wang Jing Ma Xin Li Xinmiao Xian Guikun Tan Hongwei Cai Bingwu Yang Anqi Zhang Jianran Guo Guohao Gu Zhen Meng Bo Fu Source Type: research
A Crosstalk Between Castration-Resistant Prostate Cancer Cells, M2 Macrophages, and NK Cells: Role of the ATM-PI3K/AKT-PD-L1 Pathway
In conclusion, it could be demonstrated that inhibiting ATM increased the susceptibility of CRPC to NK cell inhibitors by dampening the CXCL12 and PI3K/AKT-PD-L1 pathways, thereby offering a novel and individualized treatment protocol for treating CRPC.PMID:37732622 | DOI:10.1080/08820139.2023.2258930 (Source: Immunological Investigations)
Source: Immunological Investigations - September 21, 2023 Category: Allergy & Immunology Authors: Hongliang Jin Jin Zhu Rui Xuan Yibin Zhou Boxin Xue Dongrong Yang Jie Gao Yachen Zang Lijun Xu Source Type: research
EGR-1 Contributes to Pulmonary Edema by Regulating the Epithelial Sodium Channel in Lipopolysaccharide-Induced Acute Lung Injury
In conclusion, our study demonstrated that EGR-1 could promote pulmonary edema by downregulating ENaC-α at the transcriptional level in ALI. Our study provides a new potential therapeutic strategy for treatment of ALI.PMID:37732637 | DOI:10.1080/08820139.2023.2256778 (Source: Immunological Investigations)
Source: Immunological Investigations - September 21, 2023 Category: Allergy & Immunology Authors: Song Wang Jing Ma Xin Li Xinmiao Xian Guikun Tan Hongwei Cai Bingwu Yang Anqi Zhang Jianran Guo Guohao Gu Zhen Meng Bo Fu Source Type: research
Sodium Butyrate Protects Against Intestinal Oxidative Damage and Neuroinflammation in the Prefrontal Cortex of Ulcerative Colitis Mice Model
Immunol Invest. 2023 Nov;52(7):796-814. doi: 10.1080/08820139.2023.2244967. Epub 2023 Sep 4.ABSTRACTInflammatory bowel diseases (IBD) cause increased inflammatory signalling and oxidative damage. IBDs are correlated with an increased incidence of brain-related disorders suggesting that the gut-brain-axis exerts a pivotal role in IBD. Butyrate is one of the main microbial metabolites in the colon, and it can cross the blood-brain barrier, directly affecting the brain. We induced ulcerative colitis (UC) in mice utilizing dextran sodium sulfate (DSS) in the drinking water for 7 days. Animals were divided into four groups, rec...
Source: Immunological Investigations - September 4, 2023 Category: Allergy & Immunology Authors: Alexandre Kleber Silveira Henrique Mautone Gomes Nicole Thais Fr öhlich Luana Possa Lucas Santos Fl ávio Kessler Alberto Martins Matheus Scarpatto Rodrigues Jade De Oliveira Nat ália Duarte do Nascimento Dienifer Sirena Ana Helena Paz Daniel Pens Gelai Source Type: research
Sodium Butyrate Protects Against Intestinal Oxidative Damage and Neuroinflammation in the Prefrontal Cortex of Ulcerative Colitis Mice Model
Immunol Invest. 2023 Sep 4:1-19. doi: 10.1080/08820139.2023.2244967. Online ahead of print.ABSTRACTInflammatory bowel diseases (IBD) cause increased inflammatory signalling and oxidative damage. IBDs are correlated with an increased incidence of brain-related disorders suggesting that the gut-brain-axis exerts a pivotal role in IBD. Butyrate is one of the main microbial metabolites in the colon, and it can cross the blood-brain barrier, directly affecting the brain. We induced ulcerative colitis (UC) in mice utilizing dextran sodium sulfate (DSS) in the drinking water for 7 days. Animals were divided into four groups, rece...
Source: Immunological Investigations - September 4, 2023 Category: Allergy & Immunology Authors: Alexandre Kleber Silveira Henrique Mautone Gomes Nicole Thais Fr öhlich Luana Possa Lucas Santos Fl ávio Kessler Alberto Martins Matheus Scarpatto Rodrigues Jade De Oliveira Nat ália Duarte do Nascimento Dienifer Sirena Ana Helena Paz Daniel Pens Gelai Source Type: research
