The effects of periodic and noisy tendon vibration on a kinesthetic targeting task
Exp Brain Res. 2023 Nov 13. doi: 10.1007/s00221-023-06727-1. Online ahead of print.ABSTRACTTendon vibration is used extensively to assess the role of peripheral mechanoreceptors in motor control, specifically, the muscle spindles. Periodic tendon vibration is known to activate muscle spindles and induce a kinesthetic illusion that the vibrated muscle is longer than it actually is. Noisy tendon vibration has been used to assess the frequency characteristics of proprioceptive reflex pathways during standing; however, it is unknown if it induces the same kinesthetic illusions as periodic vibration. The purpose of the current ...
Source: Experimental Brain Research - November 13, 2023 Category: Neuroscience Authors: Gregg Eschelmuller Annika Szarka Braelyn Gandossi J Timothy Inglis Romeo Chua Source Type: research
Transcranial direct current stimulation facilitates backward walking training
Exp Brain Res. 2023 Nov 13. doi: 10.1007/s00221-023-06728-0. Online ahead of print.ABSTRACTBackward walking training presents a great challenge to the physical and neural systems, which may result in an improvement in gait performance. Transcranial direct current electrical stimulation (tDCS), which can non-invasively enhance cortical activity, has been reported to strengthen corticomotor plasticity. We investigated whether excitatory tDCS over the primary motor cortex (M1) or the dorsolateral prefrontal cortex (DLPFC) enhances the effects of backward walking training in healthy participants. Thirty-six healthy participant...
Source: Experimental Brain Research - November 13, 2023 Category: Neuroscience Authors: Ayuka Sasaki Anri Aisawa Naoyuki Takeuchi Source Type: research
The effects of periodic and noisy tendon vibration on a kinesthetic targeting task
Exp Brain Res. 2023 Nov 13. doi: 10.1007/s00221-023-06727-1. Online ahead of print.ABSTRACTTendon vibration is used extensively to assess the role of peripheral mechanoreceptors in motor control, specifically, the muscle spindles. Periodic tendon vibration is known to activate muscle spindles and induce a kinesthetic illusion that the vibrated muscle is longer than it actually is. Noisy tendon vibration has been used to assess the frequency characteristics of proprioceptive reflex pathways during standing; however, it is unknown if it induces the same kinesthetic illusions as periodic vibration. The purpose of the current ...
Source: Experimental Brain Research - November 13, 2023 Category: Neuroscience Authors: Gregg Eschelmuller Annika Szarka Braelyn Gandossi J Timothy Inglis Romeo Chua Source Type: research
Transcranial direct current stimulation facilitates backward walking training
Exp Brain Res. 2023 Nov 13. doi: 10.1007/s00221-023-06728-0. Online ahead of print.ABSTRACTBackward walking training presents a great challenge to the physical and neural systems, which may result in an improvement in gait performance. Transcranial direct current electrical stimulation (tDCS), which can non-invasively enhance cortical activity, has been reported to strengthen corticomotor plasticity. We investigated whether excitatory tDCS over the primary motor cortex (M1) or the dorsolateral prefrontal cortex (DLPFC) enhances the effects of backward walking training in healthy participants. Thirty-six healthy participant...
Source: Experimental Brain Research - November 13, 2023 Category: Neuroscience Authors: Ayuka Sasaki Anri Aisawa Naoyuki Takeuchi Source Type: research
Effects of sensory modality and task relevance on omitted stimulus potentials
Exp Brain Res. 2023 Nov 10. doi: 10.1007/s00221-023-06726-2. Online ahead of print.ABSTRACTOmitted stimulus potentials (OSPs) occur when a sensory stimulus is unexpectedly omitted. They are thought to reflect predictions about upcoming sensory events. The present study examined how OSPs differ across the sensory modalities of predicted stimuli. Twenty-nine university students were asked to press a mouse button at a regular interval of 1-2 s, which was immediately followed by either a visual or auditory stimulus in different blocks. The stimuli were sometimes omitted (p = 0.2), to which event-related potentials (ERPs) were ...
Source: Experimental Brain Research - November 10, 2023 Category: Neuroscience Authors: Tomomi Ishida Hiroshi Nittono Source Type: research
Effects of sensory modality and task relevance on omitted stimulus potentials
Exp Brain Res. 2023 Nov 10. doi: 10.1007/s00221-023-06726-2. Online ahead of print.ABSTRACTOmitted stimulus potentials (OSPs) occur when a sensory stimulus is unexpectedly omitted. They are thought to reflect predictions about upcoming sensory events. The present study examined how OSPs differ across the sensory modalities of predicted stimuli. Twenty-nine university students were asked to press a mouse button at a regular interval of 1-2 s, which was immediately followed by either a visual or auditory stimulus in different blocks. The stimuli were sometimes omitted (p = 0.2), to which event-related potentials (ERPs) were ...
Source: Experimental Brain Research - November 10, 2023 Category: Neuroscience Authors: Tomomi Ishida Hiroshi Nittono Source Type: research
Effects of sensory modality and task relevance on omitted stimulus potentials
Exp Brain Res. 2023 Nov 10. doi: 10.1007/s00221-023-06726-2. Online ahead of print.ABSTRACTOmitted stimulus potentials (OSPs) occur when a sensory stimulus is unexpectedly omitted. They are thought to reflect predictions about upcoming sensory events. The present study examined how OSPs differ across the sensory modalities of predicted stimuli. Twenty-nine university students were asked to press a mouse button at a regular interval of 1-2 s, which was immediately followed by either a visual or auditory stimulus in different blocks. The stimuli were sometimes omitted (p = 0.2), to which event-related potentials (ERPs) were ...
Source: Experimental Brain Research - November 10, 2023 Category: Neuroscience Authors: Tomomi Ishida Hiroshi Nittono Source Type: research
MicroRNA-124 conducts neuroprotective effect via inhibiting AK4/ATF3 after subarachnoid hemorrhage
This study aims to explore the role of miR-124 in the early post-SAH period on neural function and verify whether it is involved in the pathological and physiological processes of SAH. In this study, we used methods such as comparing the expression levels of miR-124 in cerebrospinal fluid, establishing a rat SAH model, and a mouse embryonic primary neuron hemoglobin stimulation model to verify the downstream proteins of miR-124 in SAH. Through transfection techniques, we adjusted the expression of this small RNA in Vitro and in Vivo models using miR-124 inhibitor and mimic in the primary neuron hemoglobin stimulation model...
Source: Experimental Brain Research - November 6, 2023 Category: Neuroscience Authors: Wei Jiang Qingge Jia Hongxin Ma Song Han Shijun Bi Kunyuan Zhu Ligang Chen Guobiao Liang Source Type: research
MicroRNA-124 conducts neuroprotective effect via inhibiting AK4/ATF3 after subarachnoid hemorrhage
This study aims to explore the role of miR-124 in the early post-SAH period on neural function and verify whether it is involved in the pathological and physiological processes of SAH. In this study, we used methods such as comparing the expression levels of miR-124 in cerebrospinal fluid, establishing a rat SAH model, and a mouse embryonic primary neuron hemoglobin stimulation model to verify the downstream proteins of miR-124 in SAH. Through transfection techniques, we adjusted the expression of this small RNA in Vitro and in Vivo models using miR-124 inhibitor and mimic in the primary neuron hemoglobin stimulation model...
Source: Experimental Brain Research - November 6, 2023 Category: Neuroscience Authors: Wei Jiang Qingge Jia Hongxin Ma Song Han Shijun Bi Kunyuan Zhu Ligang Chen Guobiao Liang Source Type: research
MicroRNA-124 conducts neuroprotective effect via inhibiting AK4/ATF3 after subarachnoid hemorrhage
This study aims to explore the role of miR-124 in the early post-SAH period on neural function and verify whether it is involved in the pathological and physiological processes of SAH. In this study, we used methods such as comparing the expression levels of miR-124 in cerebrospinal fluid, establishing a rat SAH model, and a mouse embryonic primary neuron hemoglobin stimulation model to verify the downstream proteins of miR-124 in SAH. Through transfection techniques, we adjusted the expression of this small RNA in Vitro and in Vivo models using miR-124 inhibitor and mimic in the primary neuron hemoglobin stimulation model...
Source: Experimental Brain Research - November 6, 2023 Category: Neuroscience Authors: Wei Jiang Qingge Jia Hongxin Ma Song Han Shijun Bi Kunyuan Zhu Ligang Chen Guobiao Liang Source Type: research
MicroRNA-124 conducts neuroprotective effect via inhibiting AK4/ATF3 after subarachnoid hemorrhage
This study aims to explore the role of miR-124 in the early post-SAH period on neural function and verify whether it is involved in the pathological and physiological processes of SAH. In this study, we used methods such as comparing the expression levels of miR-124 in cerebrospinal fluid, establishing a rat SAH model, and a mouse embryonic primary neuron hemoglobin stimulation model to verify the downstream proteins of miR-124 in SAH. Through transfection techniques, we adjusted the expression of this small RNA in Vitro and in Vivo models using miR-124 inhibitor and mimic in the primary neuron hemoglobin stimulation model...
Source: Experimental Brain Research - November 6, 2023 Category: Neuroscience Authors: Wei Jiang Qingge Jia Hongxin Ma Song Han Shijun Bi Kunyuan Zhu Ligang Chen Guobiao Liang Source Type: research
Fibroblast growth factor-21 alleviates proteasome injury via activation of autophagy flux in Parkinson's disease
Exp Brain Res. 2023 Nov 1. doi: 10.1007/s00221-023-06709-3. Online ahead of print.ABSTRACTParkinson's disease (PD) is one of the most common and complex Neurodegeneration, with an inherited metabolic disorder. Fibroblast growth factor 21 (FGF21), an endocrine hormone that belongs to the fibroblast growth factor superfamily, plays an extensive role in metabolic regulation. However, our understandings of the specific function and mechanisms of FGF21 on PD are still quite limited. Here, we aimed to elucidate the actions and the underlying mechanisms of FGF21 on dopaminergic neurodegeneration using cellular models of parkinson...
Source: Experimental Brain Research - November 1, 2023 Category: Neuroscience Authors: Yufei Shen Zhuoying Zhu Yanping Wang Shuxia Qian Congying Xu Baorong Zhang Source Type: research
Fibroblast growth factor-21 alleviates proteasome injury via activation of autophagy flux in Parkinson's disease
Exp Brain Res. 2023 Nov 1. doi: 10.1007/s00221-023-06709-3. Online ahead of print.ABSTRACTParkinson's disease (PD) is one of the most common and complex Neurodegeneration, with an inherited metabolic disorder. Fibroblast growth factor 21 (FGF21), an endocrine hormone that belongs to the fibroblast growth factor superfamily, plays an extensive role in metabolic regulation. However, our understandings of the specific function and mechanisms of FGF21 on PD are still quite limited. Here, we aimed to elucidate the actions and the underlying mechanisms of FGF21 on dopaminergic neurodegeneration using cellular models of parkinson...
Source: Experimental Brain Research - November 1, 2023 Category: Neuroscience Authors: Yufei Shen Zhuoying Zhu Yanping Wang Shuxia Qian Congying Xu Baorong Zhang Source Type: research
Fibroblast growth factor-21 alleviates proteasome injury via activation of autophagy flux in Parkinson's disease
Exp Brain Res. 2023 Nov 1. doi: 10.1007/s00221-023-06709-3. Online ahead of print.ABSTRACTParkinson's disease (PD) is one of the most common and complex Neurodegeneration, with an inherited metabolic disorder. Fibroblast growth factor 21 (FGF21), an endocrine hormone that belongs to the fibroblast growth factor superfamily, plays an extensive role in metabolic regulation. However, our understandings of the specific function and mechanisms of FGF21 on PD are still quite limited. Here, we aimed to elucidate the actions and the underlying mechanisms of FGF21 on dopaminergic neurodegeneration using cellular models of parkinson...
Source: Experimental Brain Research - November 1, 2023 Category: Neuroscience Authors: Yufei Shen Zhuoying Zhu Yanping Wang Shuxia Qian Congying Xu Baorong Zhang Source Type: research
Fibroblast growth factor-21 alleviates proteasome injury via activation of autophagy flux in Parkinson's disease
Exp Brain Res. 2023 Nov 1. doi: 10.1007/s00221-023-06709-3. Online ahead of print.ABSTRACTParkinson's disease (PD) is one of the most common and complex Neurodegeneration, with an inherited metabolic disorder. Fibroblast growth factor 21 (FGF21), an endocrine hormone that belongs to the fibroblast growth factor superfamily, plays an extensive role in metabolic regulation. However, our understandings of the specific function and mechanisms of FGF21 on PD are still quite limited. Here, we aimed to elucidate the actions and the underlying mechanisms of FGF21 on dopaminergic neurodegeneration using cellular models of parkinson...
Source: Experimental Brain Research - November 1, 2023 Category: Neuroscience Authors: Yufei Shen Zhuoying Zhu Yanping Wang Shuxia Qian Congying Xu Baorong Zhang Source Type: research
