Activation of NLRP3 inflammasome in a rat model of cerebral small vessel disease
Exp Brain Res. 2024 Apr 2. doi: 10.1007/s00221-024-06824-9. Online ahead of print.ABSTRACTCerebral small vessel disease (CSVD) is increasingly being recognized as a leading contributor to cognitive impairment in the elderly. However, there is a lack of effective preventative or therapeutic options for CSVD. In this exploratory study, we investigated the interplay between neuroinflammation and CSVD pathogenesis as well as the cognitive performance, focusing on NLRP3 signaling as a new therapeutic target. Spontaneously hypertensive stroke-prone (SHRSP) rats served as a CSVD model. We found that SHRSP rats showed decline in l...
Source: Experimental Brain Research - April 2, 2024 Category: Neuroscience Authors: Meiyan Zhang Xiaoyan Lan Yue Gao Yu Zou Shen Li Yajie Liang Miroslaw Janowski Piotr Walczak Chengyan Chu Source Type: research
The center of a face catches the eye in face perception
This study not only reveals this explanation but also raises a question regarding the CoG effect on Eastern participants.PMID:38563980 | DOI:10.1007/s00221-024-06822-x (Source: Experimental Brain Research)
Source: Experimental Brain Research - April 2, 2024 Category: Neuroscience Authors: Toshikazu Kawagoe Wataru Teramoto Source Type: research
The impact of weight and negative body image on the body schema in undergraduate women
CONCLUSIONS: These results imply that body dissatisfaction and thinness are predictors of massive body schema distortions. An oversized body schema could maintain various weight-control behaviors, thus risking the development, maintenance, or relapse of an eating disorder.PMID:38565782 | DOI:10.1007/s00221-024-06827-6 (Source: Experimental Brain Research)
Source: Experimental Brain Research - April 2, 2024 Category: Neuroscience Authors: Jean-David Boucher Jessica Bourgin Johana Lassiaz Klervi Propice Morgane Metral Source Type: research
Gaze data of 4243 participants shows link between leftward and superior attention biases and age
Exp Brain Res. 2024 Mar 31. doi: 10.1007/s00221-024-06823-w. Online ahead of print.ABSTRACTHealthy individuals typically show more attention to the left than to the right (known as pseudoneglect), and to the upper than to the lower visual field (known as altitudinal pseudoneglect). These biases are thought to reflect asymmetries in neural processes. Attention biases have been used to investigate how these neural asymmetries change with age. However, inconsistent results have been reported regarding the presence and direction of age-related effects on horizontal and vertical attention biases. The observed inconsistencies ma...
Source: Experimental Brain Research - March 31, 2024 Category: Neuroscience Authors: Christoph Strauch Alex J Hoogerbrugge Antonia F Ten Brink Source Type: research
Gaze data of 4243 participants shows link between leftward and superior attention biases and age
Exp Brain Res. 2024 Mar 31. doi: 10.1007/s00221-024-06823-w. Online ahead of print.ABSTRACTHealthy individuals typically show more attention to the left than to the right (known as pseudoneglect), and to the upper than to the lower visual field (known as altitudinal pseudoneglect). These biases are thought to reflect asymmetries in neural processes. Attention biases have been used to investigate how these neural asymmetries change with age. However, inconsistent results have been reported regarding the presence and direction of age-related effects on horizontal and vertical attention biases. The observed inconsistencies ma...
Source: Experimental Brain Research - March 31, 2024 Category: Neuroscience Authors: Christoph Strauch Alex J Hoogerbrugge Antonia F Ten Brink Source Type: research
Gaze data of 4243 participants shows link between leftward and superior attention biases and age
Exp Brain Res. 2024 Mar 31. doi: 10.1007/s00221-024-06823-w. Online ahead of print.ABSTRACTHealthy individuals typically show more attention to the left than to the right (known as pseudoneglect), and to the upper than to the lower visual field (known as altitudinal pseudoneglect). These biases are thought to reflect asymmetries in neural processes. Attention biases have been used to investigate how these neural asymmetries change with age. However, inconsistent results have been reported regarding the presence and direction of age-related effects on horizontal and vertical attention biases. The observed inconsistencies ma...
Source: Experimental Brain Research - March 31, 2024 Category: Neuroscience Authors: Christoph Strauch Alex J Hoogerbrugge Antonia F Ten Brink Source Type: research
Effects of older age on visual and self-motion sensory cue integration in navigation
Exp Brain Res. 2024 Mar 28. doi: 10.1007/s00221-024-06818-7. Online ahead of print.ABSTRACTOlder adults demonstrate impairments in navigation that cannot be explained by general cognitive and motor declines. Previous work has shown that older adults may combine sensory cues during navigation differently than younger adults, though this work has largely been done in dark environments where sensory integration may differ from full-cue environments. Here, we test whether aging adults optimally combine cues from two sensory systems critical for navigation: vision (landmarks) and body-based self-motion cues. Participants comple...
Source: Experimental Brain Research - March 29, 2024 Category: Neuroscience Authors: Corey S Shayman Maggie K McCracken Hunter C Finney Andoni M Katsanevas Peter C Fino Jeanine K Stefanucci Sarah H Creem-Regehr Source Type: research
Brain waves and landscape settings: emotional responses to attractiveness
In this study, we investigated how changes in elements of attractiveness influence ones' emotional perception and present the related pattern of changes in brain activities. Therefore, we implied five elements of attractiveness including mystery, visual openness, landscape or greenness, walkability, and social interaction using the Delphi method. Then, we made changes in each element separately to make the landscape more attractive and assessed their effects on a group of young adults. We used the self-assessment manikin questionnaire to measure the participants' emotional perception while the participants' brain activitie...
Source: Experimental Brain Research - March 29, 2024 Category: Neuroscience Authors: Zahra Karami Seyed-Abbas Yazdanfar Maryam Kashefpour Reza Khosrowabadi Source Type: research
The expression of decision and learning variables in movement patterns related to decision actions
Exp Brain Res. 2024 Mar 29. doi: 10.1007/s00221-024-06805-y. Online ahead of print.ABSTRACTDecisions are not necessarily easy to separate into a planning and an execution phase and the decision-making process can often be reflected in the movement associated with the decision. Here, we used formalized definitions of concepts relevant in decision-making and learning to explore if and how these concepts correlate with decision-related movement paths, both during and after a choice is made. To this end, we let 120 participants (46 males, mean age = 24.5 years) undergo a repeated probabilistic two-choice task with changing pro...
Source: Experimental Brain Research - March 29, 2024 Category: Neuroscience Authors: Ida Selbing Joshua Skewes Source Type: research
Systematic review and meta-analysis of randomized controlled trials on the effects of exercise interventions on amyloid beta levels in humans
Exp Brain Res. 2024 Mar 29. doi: 10.1007/s00221-024-06821-y. Online ahead of print.ABSTRACTAlzheimer's disease (AD) represents the most common type of dementia. A crucial mechanism attributed to its development is amyloid beta (Aβ) dynamics dysregulation. The extent to which exercise can modulate this phenomenon is uncertain. The aim of this study was to summarize the existing literature evaluating this issue. A comprehensive systematic search was performed in Pubmed, Scopus, Embase, Web of Science, and SciELO databases and completed in August 2023, aiming to identify randomized controlled trials investigating the effect ...
Source: Experimental Brain Research - March 29, 2024 Category: Neuroscience Authors: Isabela Mayer Pucci Andreo F Aguiar Rodrigo M Pucci Juliano Casonatto Sergio Marques Borghi Source Type: research
Exercise-induced central and peripheral sympathetic activity in a community-based group of epilepsy patients differ from healthy controls
In this study, exercise-induced changes of the interrelation of central and peripheral autonomic activity in patients with epilepsy was assessed. 21 patients with epilepsy (16 seizure-free), and 21 healthy matched controls performed an exhaustive bicycle ergometer test. Immediately before and after the exercise test, resting state electroencephalography measurements (Brain Products GmbH, 128-channel actiCHamp) of 5 min were carried out to investigate functional connectivity assessed by phase locking value in source space for whole brain, central autonomic network and visual network. Additionally, 1-lead ECG (Brain products...
Source: Experimental Brain Research - March 29, 2024 Category: Neuroscience Authors: Franziska van den Bongard Julia Kristin Gowik Jessica Coenen Rasmus Jakobsmeyer Claus Reinsberger Source Type: research
Effects of older age on visual and self-motion sensory cue integration in navigation
Exp Brain Res. 2024 Mar 28. doi: 10.1007/s00221-024-06818-7. Online ahead of print.ABSTRACTOlder adults demonstrate impairments in navigation that cannot be explained by general cognitive and motor declines. Previous work has shown that older adults may combine sensory cues during navigation differently than younger adults, though this work has largely been done in dark environments where sensory integration may differ from full-cue environments. Here, we test whether aging adults optimally combine cues from two sensory systems critical for navigation: vision (landmarks) and body-based self-motion cues. Participants comple...
Source: Experimental Brain Research - March 29, 2024 Category: Neuroscience Authors: Corey S Shayman Maggie K McCracken Hunter C Finney Andoni M Katsanevas Peter C Fino Jeanine K Stefanucci Sarah H Creem-Regehr Source Type: research
Brain waves and landscape settings: emotional responses to attractiveness
In this study, we investigated how changes in elements of attractiveness influence ones' emotional perception and present the related pattern of changes in brain activities. Therefore, we implied five elements of attractiveness including mystery, visual openness, landscape or greenness, walkability, and social interaction using the Delphi method. Then, we made changes in each element separately to make the landscape more attractive and assessed their effects on a group of young adults. We used the self-assessment manikin questionnaire to measure the participants' emotional perception while the participants' brain activitie...
Source: Experimental Brain Research - March 29, 2024 Category: Neuroscience Authors: Zahra Karami Seyed-Abbas Yazdanfar Maryam Kashefpour Reza Khosrowabadi Source Type: research
The expression of decision and learning variables in movement patterns related to decision actions
Exp Brain Res. 2024 Mar 29. doi: 10.1007/s00221-024-06805-y. Online ahead of print.ABSTRACTDecisions are not necessarily easy to separate into a planning and an execution phase and the decision-making process can often be reflected in the movement associated with the decision. Here, we used formalized definitions of concepts relevant in decision-making and learning to explore if and how these concepts correlate with decision-related movement paths, both during and after a choice is made. To this end, we let 120 participants (46 males, mean age = 24.5 years) undergo a repeated probabilistic two-choice task with changing pro...
Source: Experimental Brain Research - March 29, 2024 Category: Neuroscience Authors: Ida Selbing Joshua Skewes Source Type: research
Systematic review and meta-analysis of randomized controlled trials on the effects of exercise interventions on amyloid beta levels in humans
Exp Brain Res. 2024 Mar 29. doi: 10.1007/s00221-024-06821-y. Online ahead of print.ABSTRACTAlzheimer's disease (AD) represents the most common type of dementia. A crucial mechanism attributed to its development is amyloid beta (Aβ) dynamics dysregulation. The extent to which exercise can modulate this phenomenon is uncertain. The aim of this study was to summarize the existing literature evaluating this issue. A comprehensive systematic search was performed in Pubmed, Scopus, Embase, Web of Science, and SciELO databases and completed in August 2023, aiming to identify randomized controlled trials investigating the effect ...
Source: Experimental Brain Research - March 29, 2024 Category: Neuroscience Authors: Isabela Mayer Pucci Andreo F Aguiar Rodrigo M Pucci Juliano Casonatto Sergio Marques Borghi Source Type: research
