The topographical attenuation of cutaneous input is modulated at the ankle joint during gait
Exp Brain Res. 2023 Nov 18. doi: 10.1007/s00221-023-06737-z. Online ahead of print.ABSTRACTThe attenuation of sensory inputs via various methods has been demonstrated to impair balance control and alter locomotor behavior during human walking; however, the effects of attenuating foot sole sensation under distinct areas of the foot sole on lower extremity motor output remains poorly understood. Thus, the purpose of this study was to attenuate cutaneous feedback via regional hypothermia under five different areas of the foot sole and investigate the resultant modulation of kinematic and muscle activity during level walking. ...
Source: Experimental Brain Research - November 18, 2023 Category: Neuroscience Authors: Kelly A Robb Stephen D Perry Source Type: research
Exploring EEG resting state as a function of boredom proneness in pre-adolescents and adolescents
Exp Brain Res. 2023 Nov 17. doi: 10.1007/s00221-023-06733-3. Online ahead of print.ABSTRACTBoredom is a prominent experience commonly reported in school settings and associated with poor academic achievement. Little is known, however, about the age-related trajectory of boredom. Here we examined self-reported ratings of boredom in a cross-sectional sample of 8 to 15-year olds (n = 185) as a function of resting state EEG. Results indicated that reports of boredom in school rose as a function of age. Resting state EEG showed a decrease in theta power with age perhaps reflective of increased control. While no effects were evi...
Source: Experimental Brain Research - November 17, 2023 Category: Neuroscience Authors: Jamie Nettinga Sarah Naseem Ofir Yakobi Teena Willoughby James Danckert Source Type: research
The P38MAPK/ATF2 signaling pathway is involved in PND in mice
This study aims to investigate the role of the P38MAPK/ATF2 signaling pathway in the development of PND in mice. Aged C57BL/6 mice were subjected to tibial fracture surgery under isoflurane anesthesia to establish a PND animal model. The open field test was used to evaluate the locomotor activity of the mice. Neurocognitive function was assessed with the Morris water maze (MWM) and fear conditioning test (FCT) on postoperative days 1, 3 and 7. The mice exhibited cognitive impairment accompanied by increased expression of proinflammatory factors (IL-1β, TNF-α), proapoptotic molecules (caspase-3, bax) and microglial activa...
Source: Experimental Brain Research - November 16, 2023 Category: Neuroscience Authors: Mengjiao Zhu Si Long Yizhi Tao Zhifa Zhang Zhiqiang Zhou Xueren Wang Wei Chen Source Type: research
Changes in vestibular-related responses to combined noisy galvanic vestibular stimulation and cerebellar transcranial direct current stimulation
This study aimed to examine whether the combination of noisy galvanic vestibular stimulation (nGVS) and cerebellar transcranial direct current stimulation (ctDCS) using a complex transcranial electrical stimulation device alters vestibular-dominant standing stability and vestibulo-ocular reflex (VOR) function. The center of foot pressure (COP) sway and VOR of participants (28 healthy, young adults) were assessed under four conditions of transcranial electrical stimulation using nGVS and ctDCS. The COP was calculated with the participant standing on a soft-foam surface with eyes closed using a force plate to evaluate body s...
Source: Experimental Brain Research - November 15, 2023 Category: Neuroscience Authors: Tsubasa Mitsutake Hisato Nakazono Tomoyuki Shiozaki Daisuke Fujita Maiko Sakamoto Source Type: research
Changes in vestibular-related responses to combined noisy galvanic vestibular stimulation and cerebellar transcranial direct current stimulation
This study aimed to examine whether the combination of noisy galvanic vestibular stimulation (nGVS) and cerebellar transcranial direct current stimulation (ctDCS) using a complex transcranial electrical stimulation device alters vestibular-dominant standing stability and vestibulo-ocular reflex (VOR) function. The center of foot pressure (COP) sway and VOR of participants (28 healthy, young adults) were assessed under four conditions of transcranial electrical stimulation using nGVS and ctDCS. The COP was calculated with the participant standing on a soft-foam surface with eyes closed using a force plate to evaluate body s...
Source: Experimental Brain Research - November 15, 2023 Category: Neuroscience Authors: Tsubasa Mitsutake Hisato Nakazono Tomoyuki Shiozaki Daisuke Fujita Maiko Sakamoto Source Type: research
Changes in vestibular-related responses to combined noisy galvanic vestibular stimulation and cerebellar transcranial direct current stimulation
This study aimed to examine whether the combination of noisy galvanic vestibular stimulation (nGVS) and cerebellar transcranial direct current stimulation (ctDCS) using a complex transcranial electrical stimulation device alters vestibular-dominant standing stability and vestibulo-ocular reflex (VOR) function. The center of foot pressure (COP) sway and VOR of participants (28 healthy, young adults) were assessed under four conditions of transcranial electrical stimulation using nGVS and ctDCS. The COP was calculated with the participant standing on a soft-foam surface with eyes closed using a force plate to evaluate body s...
Source: Experimental Brain Research - November 15, 2023 Category: Neuroscience Authors: Tsubasa Mitsutake Hisato Nakazono Tomoyuki Shiozaki Daisuke Fujita Maiko Sakamoto Source Type: research
The effect and efficiency of attentional networks and the brain electrophysiology
This study aimed to examine the relationship between attention networks and brain electrophysiology. The study enrolled 40 right-handed male students (age = 20.8 ± 1.3 years) who underwent the revised attention network test, while their electroencephalogram signals were recorded. The study aimed to explore the effects of attention networks and their efficiencies on brain electrophysiology. The results indicated that the P3 amplitude was modulated by the conflict effect in the central (p-value = 0.014) and parietal (p-value = 0.002) regions. The orienting component significantly influenced P1 and N1 latencies in the pariet...
Source: Experimental Brain Research - November 14, 2023 Category: Neuroscience Authors: Hossein Akbari-Lalimi Shahrokh Naseri Mahdi Momennezhad Hoda Zare Ali Talaei Seyed Ali Shafiei Source Type: research
The effects of periodic and noisy tendon vibration on a kinesthetic targeting task
Exp Brain Res. 2023 Nov 13. doi: 10.1007/s00221-023-06727-1. Online ahead of print.ABSTRACTTendon vibration is used extensively to assess the role of peripheral mechanoreceptors in motor control, specifically, the muscle spindles. Periodic tendon vibration is known to activate muscle spindles and induce a kinesthetic illusion that the vibrated muscle is longer than it actually is. Noisy tendon vibration has been used to assess the frequency characteristics of proprioceptive reflex pathways during standing; however, it is unknown if it induces the same kinesthetic illusions as periodic vibration. The purpose of the current ...
Source: Experimental Brain Research - November 13, 2023 Category: Neuroscience Authors: Gregg Eschelmuller Annika Szarka Braelyn Gandossi J Timothy Inglis Romeo Chua Source Type: research
Transcranial direct current stimulation facilitates backward walking training
Exp Brain Res. 2023 Nov 13. doi: 10.1007/s00221-023-06728-0. Online ahead of print.ABSTRACTBackward walking training presents a great challenge to the physical and neural systems, which may result in an improvement in gait performance. Transcranial direct current electrical stimulation (tDCS), which can non-invasively enhance cortical activity, has been reported to strengthen corticomotor plasticity. We investigated whether excitatory tDCS over the primary motor cortex (M1) or the dorsolateral prefrontal cortex (DLPFC) enhances the effects of backward walking training in healthy participants. Thirty-six healthy participant...
Source: Experimental Brain Research - November 13, 2023 Category: Neuroscience Authors: Ayuka Sasaki Anri Aisawa Naoyuki Takeuchi Source Type: research
The effects of periodic and noisy tendon vibration on a kinesthetic targeting task
Exp Brain Res. 2023 Nov 13. doi: 10.1007/s00221-023-06727-1. Online ahead of print.ABSTRACTTendon vibration is used extensively to assess the role of peripheral mechanoreceptors in motor control, specifically, the muscle spindles. Periodic tendon vibration is known to activate muscle spindles and induce a kinesthetic illusion that the vibrated muscle is longer than it actually is. Noisy tendon vibration has been used to assess the frequency characteristics of proprioceptive reflex pathways during standing; however, it is unknown if it induces the same kinesthetic illusions as periodic vibration. The purpose of the current ...
Source: Experimental Brain Research - November 13, 2023 Category: Neuroscience Authors: Gregg Eschelmuller Annika Szarka Braelyn Gandossi J Timothy Inglis Romeo Chua Source Type: research
Transcranial direct current stimulation facilitates backward walking training
Exp Brain Res. 2023 Nov 13. doi: 10.1007/s00221-023-06728-0. Online ahead of print.ABSTRACTBackward walking training presents a great challenge to the physical and neural systems, which may result in an improvement in gait performance. Transcranial direct current electrical stimulation (tDCS), which can non-invasively enhance cortical activity, has been reported to strengthen corticomotor plasticity. We investigated whether excitatory tDCS over the primary motor cortex (M1) or the dorsolateral prefrontal cortex (DLPFC) enhances the effects of backward walking training in healthy participants. Thirty-six healthy participant...
Source: Experimental Brain Research - November 13, 2023 Category: Neuroscience Authors: Ayuka Sasaki Anri Aisawa Naoyuki Takeuchi Source Type: research
Effects of sensory modality and task relevance on omitted stimulus potentials
Exp Brain Res. 2023 Nov 10. doi: 10.1007/s00221-023-06726-2. Online ahead of print.ABSTRACTOmitted stimulus potentials (OSPs) occur when a sensory stimulus is unexpectedly omitted. They are thought to reflect predictions about upcoming sensory events. The present study examined how OSPs differ across the sensory modalities of predicted stimuli. Twenty-nine university students were asked to press a mouse button at a regular interval of 1-2 s, which was immediately followed by either a visual or auditory stimulus in different blocks. The stimuli were sometimes omitted (p = 0.2), to which event-related potentials (ERPs) were ...
Source: Experimental Brain Research - November 10, 2023 Category: Neuroscience Authors: Tomomi Ishida Hiroshi Nittono Source Type: research
Effects of sensory modality and task relevance on omitted stimulus potentials
Exp Brain Res. 2023 Nov 10. doi: 10.1007/s00221-023-06726-2. Online ahead of print.ABSTRACTOmitted stimulus potentials (OSPs) occur when a sensory stimulus is unexpectedly omitted. They are thought to reflect predictions about upcoming sensory events. The present study examined how OSPs differ across the sensory modalities of predicted stimuli. Twenty-nine university students were asked to press a mouse button at a regular interval of 1-2 s, which was immediately followed by either a visual or auditory stimulus in different blocks. The stimuli were sometimes omitted (p = 0.2), to which event-related potentials (ERPs) were ...
Source: Experimental Brain Research - November 10, 2023 Category: Neuroscience Authors: Tomomi Ishida Hiroshi Nittono Source Type: research
Effects of sensory modality and task relevance on omitted stimulus potentials
Exp Brain Res. 2023 Nov 10. doi: 10.1007/s00221-023-06726-2. Online ahead of print.ABSTRACTOmitted stimulus potentials (OSPs) occur when a sensory stimulus is unexpectedly omitted. They are thought to reflect predictions about upcoming sensory events. The present study examined how OSPs differ across the sensory modalities of predicted stimuli. Twenty-nine university students were asked to press a mouse button at a regular interval of 1-2 s, which was immediately followed by either a visual or auditory stimulus in different blocks. The stimuli were sometimes omitted (p = 0.2), to which event-related potentials (ERPs) were ...
Source: Experimental Brain Research - November 10, 2023 Category: Neuroscience Authors: Tomomi Ishida Hiroshi Nittono Source Type: research
MicroRNA-124 conducts neuroprotective effect via inhibiting AK4/ATF3 after subarachnoid hemorrhage
This study aims to explore the role of miR-124 in the early post-SAH period on neural function and verify whether it is involved in the pathological and physiological processes of SAH. In this study, we used methods such as comparing the expression levels of miR-124 in cerebrospinal fluid, establishing a rat SAH model, and a mouse embryonic primary neuron hemoglobin stimulation model to verify the downstream proteins of miR-124 in SAH. Through transfection techniques, we adjusted the expression of this small RNA in Vitro and in Vivo models using miR-124 inhibitor and mimic in the primary neuron hemoglobin stimulation model...
Source: Experimental Brain Research - November 6, 2023 Category: Neuroscience Authors: Wei Jiang Qingge Jia Hongxin Ma Song Han Shijun Bi Kunyuan Zhu Ligang Chen Guobiao Liang Source Type: research
