CircNCOA4 knockdown attenuates OGD-induced neuron injury through miR-338-5p/PDE4B axis
Exp Brain Res. 2023 Sep 16. doi: 10.1007/s00221-023-06702-w. Online ahead of print.ABSTRACTCircular RNAs (circRNAs) have been revealed to be involved in the pathology of acute ischemic stroke (AIS). Herein, we aimed to study the role and mechanism of circNCOA4 in ischemic stroke. The neuron-like cell line SK-N-SH of the experiment group was cultured in oxygen-glucose deprivation (OGD) condition. Cell viability and apoptosis were evaluated by cell counting kit-8 and flow cytometry. The oxidative damage and endoplasmic reticulum stress (ERS) were analyzed by measuring the production of reactive oxygen species (ROS), malondia...
Source: Experimental Brain Research - September 16, 2023 Category: Neuroscience Authors: Danyang Wang Sai Xiao Xiaoming Li Wenbo Qi Source Type: research

A comparison of techniques for verifying the accuracy of precision decomposition-derived relationships between motor unit firing rates and recruitment thresholds from surface EMG signals
Exp Brain Res. 2023 Sep 14. doi: 10.1007/s00221-023-06694-7. Online ahead of print.ABSTRACTApproaches for validating motor unit firing times following surface electromyographic (EMG) signal decomposition with the precision decomposition III (PDIII) algorithm have not been agreed upon. Two approaches have been common: (1) "reconstruct-and-test" and (2) spike-triggered averaging (STA). We sought to compare motor unit results following the application of these approaches. Surface EMG signals were recorded from the vastus lateralis of 13 young males performing trapezoidal, isometric knee extensions at 50% and 80% of maximum vo...
Source: Experimental Brain Research - September 14, 2023 Category: Neuroscience Authors: Jonathan P Beausejour Paul Bohlen Kylie K Harmon Ryan M Girts Jason I Pagan Debbie L Hahs-Vaughn Trent J Herda Matt S Stock Source Type: research

A comparison of techniques for verifying the accuracy of precision decomposition-derived relationships between motor unit firing rates and recruitment thresholds from surface EMG signals
Exp Brain Res. 2023 Sep 14. doi: 10.1007/s00221-023-06694-7. Online ahead of print.ABSTRACTApproaches for validating motor unit firing times following surface electromyographic (EMG) signal decomposition with the precision decomposition III (PDIII) algorithm have not been agreed upon. Two approaches have been common: (1) "reconstruct-and-test" and (2) spike-triggered averaging (STA). We sought to compare motor unit results following the application of these approaches. Surface EMG signals were recorded from the vastus lateralis of 13 young males performing trapezoidal, isometric knee extensions at 50% and 80% of maximum vo...
Source: Experimental Brain Research - September 14, 2023 Category: Neuroscience Authors: Jonathan P Beausejour Paul Bohlen Kylie K Harmon Ryan M Girts Jason I Pagan Debbie L Hahs-Vaughn Trent J Herda Matt S Stock Source Type: research

A comparison of techniques for verifying the accuracy of precision decomposition-derived relationships between motor unit firing rates and recruitment thresholds from surface EMG signals
Exp Brain Res. 2023 Sep 14. doi: 10.1007/s00221-023-06694-7. Online ahead of print.ABSTRACTApproaches for validating motor unit firing times following surface electromyographic (EMG) signal decomposition with the precision decomposition III (PDIII) algorithm have not been agreed upon. Two approaches have been common: (1) "reconstruct-and-test" and (2) spike-triggered averaging (STA). We sought to compare motor unit results following the application of these approaches. Surface EMG signals were recorded from the vastus lateralis of 13 young males performing trapezoidal, isometric knee extensions at 50% and 80% of maximum vo...
Source: Experimental Brain Research - September 14, 2023 Category: Neuroscience Authors: Jonathan P Beausejour Paul Bohlen Kylie K Harmon Ryan M Girts Jason I Pagan Debbie L Hahs-Vaughn Trent J Herda Matt S Stock Source Type: research

Seeing does not mean processing: where we look and the visual information we rely on change independently as we learn a novel walking task
Exp Brain Res. 2023 Sep 13. doi: 10.1007/s00221-023-06704-8. Online ahead of print.ABSTRACTPeople use vision to inform motor control strategies during walking. With practice performing a target stepping task, people shift their gaze farther ahead, transitioning from watching their feet contact the target to looking for future target locations. The shift in gaze focus suggests the role of vision in motor control changes from emphasizing feedback to feedforward control. The present study examines whether changing visual fixation location is accompanied by a similar change in reliance upon visual information. Twenty healthy y...
Source: Experimental Brain Research - September 13, 2023 Category: Neuroscience Authors: Alexander Cates Keith E Gordon Source Type: research