Experimental and Molecular Pathology This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

SARS-CoV-2 hampers dopamine production in iPSC-derived dopaminergic neurons
Exp Mol Pathol. 2023 Sep 30;134:104874. doi: 10.1016/j.yexmp.2023.104874. Online ahead of print.ABSTRACTAn increasing number of patients experiences prolonged symptoms, whose profile and timeline remain uncertain, a condition that has been defined as post COVID. The majority of recovered hospitalized patients manifests at least one persistent symptom even sixty days after the first clinical manifestation's onset. Particularly, in light of the COVID-19-related symptomatology, it has been hypothesized that SARS-CoV-2 might affect the dopamine pathway. However, no scientific evidence has been produced so far. To this end, hum...
Source: Experimental and Molecular Pathology - September 29, 2023 Category: Pathology Authors: G Cappelletti E V Carsana G Lunghi S Breviario C Vanetti A B Di Fonzo E Frattini M Magni S Zecchini M Clerici M Aureli C Fenizia Source Type: research

SARS-CoV-2 hampers dopamine production in iPSC-derived dopaminergic neurons
Exp Mol Pathol. 2023 Sep 30;134:104874. doi: 10.1016/j.yexmp.2023.104874. Online ahead of print.ABSTRACTAn increasing number of patients experiences prolonged symptoms, whose profile and timeline remain uncertain, a condition that has been defined as post COVID. The majority of recovered hospitalized patients manifests at least one persistent symptom even sixty days after the first clinical manifestation's onset. Particularly, in light of the COVID-19-related symptomatology, it has been hypothesized that SARS-CoV-2 might affect the dopamine pathway. However, no scientific evidence has been produced so far. To this end, hum...
Source: Experimental and Molecular Pathology - September 29, 2023 Category: Pathology Authors: G Cappelletti E V Carsana G Lunghi S Breviario C Vanetti A B Di Fonzo E Frattini M Magni S Zecchini M Clerici M Aureli C Fenizia Source Type: research

SARS-CoV-2 hampers dopamine production in iPSC-derived dopaminergic neurons
Exp Mol Pathol. 2023 Sep 30;134:104874. doi: 10.1016/j.yexmp.2023.104874. Online ahead of print.ABSTRACTAn increasing number of patients experiences prolonged symptoms, whose profile and timeline remain uncertain, a condition that has been defined as post COVID. The majority of recovered hospitalized patients manifests at least one persistent symptom even sixty days after the first clinical manifestation's onset. Particularly, in light of the COVID-19-related symptomatology, it has been hypothesized that SARS-CoV-2 might affect the dopamine pathway. However, no scientific evidence has been produced so far. To this end, hum...
Source: Experimental and Molecular Pathology - September 29, 2023 Category: Pathology Authors: G Cappelletti E V Carsana G Lunghi S Breviario C Vanetti A B Di Fonzo E Frattini M Magni S Zecchini M Clerici M Aureli C Fenizia Source Type: research

SARS-CoV-2 hampers dopamine production in iPSC-derived dopaminergic neurons
Exp Mol Pathol. 2023 Sep 30;134:104874. doi: 10.1016/j.yexmp.2023.104874. Online ahead of print.ABSTRACTAn increasing number of patients experiences prolonged symptoms, whose profile and timeline remain uncertain, a condition that has been defined as post COVID. The majority of recovered hospitalized patients manifests at least one persistent symptom even sixty days after the first clinical manifestation's onset. Particularly, in light of the COVID-19-related symptomatology, it has been hypothesized that SARS-CoV-2 might affect the dopamine pathway. However, no scientific evidence has been produced so far. To this end, hum...
Source: Experimental and Molecular Pathology - September 29, 2023 Category: Pathology Authors: G Cappelletti E V Carsana G Lunghi S Breviario C Vanetti A B Di Fonzo E Frattini M Magni S Zecchini M Clerici M Aureli C Fenizia Source Type: research

SARS-CoV-2 hampers dopamine production in iPSC-derived dopaminergic neurons
Exp Mol Pathol. 2023 Sep 30;134:104874. doi: 10.1016/j.yexmp.2023.104874. Online ahead of print.ABSTRACTAn increasing number of patients experiences prolonged symptoms, whose profile and timeline remain uncertain, a condition that has been defined as post COVID. The majority of recovered hospitalized patients manifests at least one persistent symptom even sixty days after the first clinical manifestation's onset. Particularly, in light of the COVID-19-related symptomatology, it has been hypothesized that SARS-CoV-2 might affect the dopamine pathway. However, no scientific evidence has been produced so far. To this end, hum...
Source: Experimental and Molecular Pathology - September 29, 2023 Category: Pathology Authors: G Cappelletti E V Carsana G Lunghi S Breviario C Vanetti A B Di Fonzo E Frattini M Magni S Zecchini M Clerici M Aureli C Fenizia Source Type: research

SARS-CoV-2 hampers dopamine production in iPSC-derived dopaminergic neurons
Exp Mol Pathol. 2023 Sep 30;134:104874. doi: 10.1016/j.yexmp.2023.104874. Online ahead of print.ABSTRACTAn increasing number of patients experiences prolonged symptoms, whose profile and timeline remain uncertain, a condition that has been defined as post COVID. The majority of recovered hospitalized patients manifests at least one persistent symptom even sixty days after the first clinical manifestation's onset. Particularly, in light of the COVID-19-related symptomatology, it has been hypothesized that SARS-CoV-2 might affect the dopamine pathway. However, no scientific evidence has been produced so far. To this end, hum...
Source: Experimental and Molecular Pathology - September 29, 2023 Category: Pathology Authors: G Cappelletti E V Carsana G Lunghi S Breviario C Vanetti A B Di Fonzo E Frattini M Magni S Zecchini M Clerici M Aureli C Fenizia Source Type: research

SARS-CoV-2 hampers dopamine production in iPSC-derived dopaminergic neurons
Exp Mol Pathol. 2023 Sep 30;134:104874. doi: 10.1016/j.yexmp.2023.104874. Online ahead of print.ABSTRACTAn increasing number of patients experiences prolonged symptoms, whose profile and timeline remain uncertain, a condition that has been defined as post COVID. The majority of recovered hospitalized patients manifests at least one persistent symptom even sixty days after the first clinical manifestation's onset. Particularly, in light of the COVID-19-related symptomatology, it has been hypothesized that SARS-CoV-2 might affect the dopamine pathway. However, no scientific evidence has been produced so far. To this end, hum...
Source: Experimental and Molecular Pathology - September 29, 2023 Category: Pathology Authors: G Cappelletti E V Carsana G Lunghi S Breviario C Vanetti A B Di Fonzo E Frattini M Magni S Zecchini M Clerici M Aureli C Fenizia Source Type: research

SARS-CoV-2 hampers dopamine production in iPSC-derived dopaminergic neurons
Exp Mol Pathol. 2023 Sep 30;134:104874. doi: 10.1016/j.yexmp.2023.104874. Online ahead of print.ABSTRACTAn increasing number of patients experiences prolonged symptoms, whose profile and timeline remain uncertain, a condition that has been defined as post COVID. The majority of recovered hospitalized patients manifests at least one persistent symptom even sixty days after the first clinical manifestation's onset. Particularly, in light of the COVID-19-related symptomatology, it has been hypothesized that SARS-CoV-2 might affect the dopamine pathway. However, no scientific evidence has been produced so far. To this end, hum...
Source: Experimental and Molecular Pathology - September 29, 2023 Category: Pathology Authors: G Cappelletti E V Carsana G Lunghi S Breviario C Vanetti A B Di Fonzo E Frattini M Magni S Zecchini M Clerici M Aureli C Fenizia Source Type: research

SARS-CoV-2 hampers dopamine production in iPSC-derived dopaminergic neurons
Exp Mol Pathol. 2023 Sep 30;134:104874. doi: 10.1016/j.yexmp.2023.104874. Online ahead of print.ABSTRACTAn increasing number of patients experiences prolonged symptoms, whose profile and timeline remain uncertain, a condition that has been defined as post COVID. The majority of recovered hospitalized patients manifests at least one persistent symptom even sixty days after the first clinical manifestation's onset. Particularly, in light of the COVID-19-related symptomatology, it has been hypothesized that SARS-CoV-2 might affect the dopamine pathway. However, no scientific evidence has been produced so far. To this end, hum...
Source: Experimental and Molecular Pathology - September 29, 2023 Category: Pathology Authors: G Cappelletti E V Carsana G Lunghi S Breviario C Vanetti A B Di Fonzo E Frattini M Magni S Zecchini M Clerici M Aureli C Fenizia Source Type: research

SARS-CoV-2 hampers dopamine production in iPSC-derived dopaminergic neurons
Exp Mol Pathol. 2023 Sep 27:104874. doi: 10.1016/j.yexmp.2023.104874. Online ahead of print.ABSTRACTAn increasing number of patients experiences prolonged symptoms, whose profile and timeline remain uncertain, a condition that has been defined as post COVID. The majority of recovered hospitalized patients manifests at least one persistent symptom even sixty days after the first clinical manifestation's onset. Particularly, in light of the COVID-19-related symptomatology, it has been hypothesized that SARS-CoV-2 might affect the dopamine pathway. However, no scientific evidence has been produced so far. To this end, human i...
Source: Experimental and Molecular Pathology - September 29, 2023 Category: Pathology Authors: G Cappelletti E V Carsana G Lunghi S Breviario C Vanetti A B Di Fonzo E Frattini M Magni S Zecchini M Clerici M Aureli C Fenizia Source Type: research

SARS-CoV-2 hampers dopamine production in iPSC-derived dopaminergic neurons
Exp Mol Pathol. 2023 Sep 27:104874. doi: 10.1016/j.yexmp.2023.104874. Online ahead of print.ABSTRACTAn increasing number of patients experiences prolonged symptoms, whose profile and timeline remain uncertain, a condition that has been defined as post COVID. The majority of recovered hospitalized patients manifests at least one persistent symptom even sixty days after the first clinical manifestation's onset. Particularly, in light of the COVID-19-related symptomatology, it has been hypothesized that SARS-CoV-2 might affect the dopamine pathway. However, no scientific evidence has been produced so far. To this end, human i...
Source: Experimental and Molecular Pathology - September 29, 2023 Category: Pathology Authors: G Cappelletti E V Carsana G Lunghi S Breviario C Vanetti A B Di Fonzo E Frattini M Magni S Zecchini M Clerici M Aureli C Fenizia Source Type: research

DNA methylation of HOX genes and its clinical implications in cancer
Exp Mol Pathol. 2023 Sep 12;134:104871. doi: 10.1016/j.yexmp.2023.104871. Online ahead of print.ABSTRACTHomeobox (HOX) genes encode highly conserved transcription factors that play vital roles in embryonic development. DNA methylation is a pivotal regulatory epigenetic signaling mark responsible for regulating gene expression. Abnormal DNA methylation is largely associated with the aberrant expression of HOX genes, which is implicated in a broad range of human diseases, including cancer. Numerous studies have clarified the mechanisms of DNA methylation in both physiological and pathological processes. In this review, we fo...
Source: Experimental and Molecular Pathology - September 11, 2023 Category: Pathology Authors: Xin Hu Yong Wang Xiaoyu Zhang Chensheng Li Xikun Zhang Dongxia Yang Yuanyuan Liu Lianlian Li Source Type: research

DNA methylation of HOX genes and its clinical implications in cancer
Exp Mol Pathol. 2023 Sep 12;134:104871. doi: 10.1016/j.yexmp.2023.104871. Online ahead of print.ABSTRACTHomeobox (HOX) genes encode highly conserved transcription factors that play vital roles in embryonic development. DNA methylation is a pivotal regulatory epigenetic signaling mark responsible for regulating gene expression. Abnormal DNA methylation is largely associated with the aberrant expression of HOX genes, which is implicated in a broad range of human diseases, including cancer. Numerous studies have clarified the mechanisms of DNA methylation in both physiological and pathological processes. In this review, we fo...
Source: Experimental and Molecular Pathology - September 11, 2023 Category: Pathology Authors: Xin Hu Yong Wang Xiaoyu Zhang Chensheng Li Xikun Zhang Dongxia Yang Yuanyuan Liu Lianlian Li Source Type: research

DNA methylation of HOX genes and its clinical implications in cancer
Exp Mol Pathol. 2023 Sep 12;134:104871. doi: 10.1016/j.yexmp.2023.104871. Online ahead of print.ABSTRACTHomeobox (HOX) genes encode highly conserved transcription factors that play vital roles in embryonic development. DNA methylation is a pivotal regulatory epigenetic signaling mark responsible for regulating gene expression. Abnormal DNA methylation is largely associated with the aberrant expression of HOX genes, which is implicated in a broad range of human diseases, including cancer. Numerous studies have clarified the mechanisms of DNA methylation in both physiological and pathological processes. In this review, we fo...
Source: Experimental and Molecular Pathology - September 11, 2023 Category: Pathology Authors: Xin Hu Yong Wang Xiaoyu Zhang Chensheng Li Xikun Zhang Dongxia Yang Yuanyuan Liu Lianlian Li Source Type: research

DNA methylation of HOX genes and its clinical implications in cancer
Exp Mol Pathol. 2023 Sep 12;134:104871. doi: 10.1016/j.yexmp.2023.104871. Online ahead of print.ABSTRACTHomeobox (HOX) genes encode highly conserved transcription factors that play vital roles in embryonic development. DNA methylation is a pivotal regulatory epigenetic signaling mark responsible for regulating gene expression. Abnormal DNA methylation is largely associated with the aberrant expression of HOX genes, which is implicated in a broad range of human diseases, including cancer. Numerous studies have clarified the mechanisms of DNA methylation in both physiological and pathological processes. In this review, we fo...
Source: Experimental and Molecular Pathology - September 11, 2023 Category: Pathology Authors: Xin Hu Yong Wang Xiaoyu Zhang Chensheng Li Xikun Zhang Dongxia Yang Yuanyuan Liu Lianlian Li Source Type: research