Experimental and Molecular Pathology This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Characterization of human umbilical cord blood-derived mast cells using high-throughput expression profiling and next-generation knowledge discovery platforms
Exp Mol Pathol. 2023 Aug 31;132-133:104867. doi: 10.1016/j.yexmp.2023.104867. Online ahead of print.ABSTRACTMast cells (MCs) are tissue-resident innate immune cells that express the high-affinity receptor for immunoglobulin E and are responsible for host defense and an array of diseases related to immune system. We aimed in this study to characterize the pathways and gene signatures of human cord blood-derived MCs (hCBMCs) in comparison to cells originating from CD34- progenitors using next-generation knowledge discovery methods. CD34+ cells were isolated from human umbilical cord blood using magnetic activated cell sortin...
Source: Experimental and Molecular Pathology - August 27, 2023 Category: Pathology Authors: Sherin Bakhashab Ghalya H Banafea Farid Ahmed Haneen Alsehli Huda F AlShaibi Nadia Bagatian Ohoud Subhi Kalamegam Gauthaman Mahmood Rasool Hans-Juergen Schulten Peter Natesan Pushparaj Source Type: research

Characterization of human umbilical cord blood-derived mast cells using high-throughput expression profiling and next-generation knowledge discovery platforms
Exp Mol Pathol. 2023 Aug 31;132-133:104867. doi: 10.1016/j.yexmp.2023.104867. Online ahead of print.ABSTRACTMast cells (MCs) are tissue-resident innate immune cells that express the high-affinity receptor for immunoglobulin E and are responsible for host defense and an array of diseases related to immune system. We aimed in this study to characterize the pathways and gene signatures of human cord blood-derived MCs (hCBMCs) in comparison to cells originating from CD34- progenitors using next-generation knowledge discovery methods. CD34+ cells were isolated from human umbilical cord blood using magnetic activated cell sortin...
Source: Experimental and Molecular Pathology - August 27, 2023 Category: Pathology Authors: Sherin Bakhashab Ghalya H Banafea Farid Ahmed Haneen Alsehli Huda F AlShaibi Nadia Bagatian Ohoud Subhi Kalamegam Gauthaman Mahmood Rasool Hans-Juergen Schulten Peter Natesan Pushparaj Source Type: research

Characterization of human umbilical cord blood-derived mast cells using high-throughput expression profiling and next-generation knowledge discovery platforms
Exp Mol Pathol. 2023 Aug 31;132-133:104867. doi: 10.1016/j.yexmp.2023.104867. Online ahead of print.ABSTRACTMast cells (MCs) are tissue-resident innate immune cells that express the high-affinity receptor for immunoglobulin E and are responsible for host defense and an array of diseases related to immune system. We aimed in this study to characterize the pathways and gene signatures of human cord blood-derived MCs (hCBMCs) in comparison to cells originating from CD34- progenitors using next-generation knowledge discovery methods. CD34+ cells were isolated from human umbilical cord blood using magnetic activated cell sortin...
Source: Experimental and Molecular Pathology - August 27, 2023 Category: Pathology Authors: Sherin Bakhashab Ghalya H Banafea Farid Ahmed Haneen Alsehli Huda F AlShaibi Nadia Bagatian Ohoud Subhi Kalamegam Gauthaman Mahmood Rasool Hans-Juergen Schulten Peter Natesan Pushparaj Source Type: research

Characterization of human umbilical cord blood-derived mast cells using high-throughput expression profiling and next-generation knowledge discovery platforms
Exp Mol Pathol. 2023 Aug 31;132-133:104867. doi: 10.1016/j.yexmp.2023.104867. Online ahead of print.ABSTRACTMast cells (MCs) are tissue-resident innate immune cells that express the high-affinity receptor for immunoglobulin E and are responsible for host defense and an array of diseases related to immune system. We aimed in this study to characterize the pathways and gene signatures of human cord blood-derived MCs (hCBMCs) in comparison to cells originating from CD34- progenitors using next-generation knowledge discovery methods. CD34+ cells were isolated from human umbilical cord blood using magnetic activated cell sortin...
Source: Experimental and Molecular Pathology - August 27, 2023 Category: Pathology Authors: Sherin Bakhashab Ghalya H Banafea Farid Ahmed Haneen Alsehli Huda F AlShaibi Nadia Bagatian Ohoud Subhi Kalamegam Gauthaman Mahmood Rasool Hans-Juergen Schulten Peter Natesan Pushparaj Source Type: research

Characterization of human umbilical cord blood-derived mast cells using high-throughput expression profiling and next-generation knowledge discovery platforms
Exp Mol Pathol. 2023 Aug 25:104867. doi: 10.1016/j.yexmp.2023.104867. Online ahead of print.ABSTRACTMast cells (MCs) are tissue-resident innate immune cells that express the high-affinity receptor for immunoglobulin E and are responsible for host defense and an array of diseases related to immune system. We aimed in this study to characterize the pathways and gene signatures of human cord blood-derived MCs (hCBMCs) in comparison to cells originating from CD34- progenitors using next-generation knowledge discovery methods. CD34+ cells were isolated from human umbilical cord blood using magnetic activated cell sorting and di...
Source: Experimental and Molecular Pathology - August 27, 2023 Category: Pathology Authors: Sherin Bakhashab Ghalya H Banafea Farid Ahmed Haneen Alsehli Huda F AlShaibi Nadia Bagatian Ohoud Subhi Kalamegam Gauthaman Mahmood Rasool Hans-Juergen Schulten Peter Natesan Pushparaj Source Type: research

Characterization of human umbilical cord blood-derived mast cells using high-throughput expression profiling and next-generation knowledge discovery platforms
Exp Mol Pathol. 2023 Aug 25:104867. doi: 10.1016/j.yexmp.2023.104867. Online ahead of print.ABSTRACTMast cells (MCs) are tissue-resident innate immune cells that express the high-affinity receptor for immunoglobulin E and are responsible for host defense and an array of diseases related to immune system. We aimed in this study to characterize the pathways and gene signatures of human cord blood-derived MCs (hCBMCs) in comparison to cells originating from CD34- progenitors using next-generation knowledge discovery methods. CD34+ cells were isolated from human umbilical cord blood using magnetic activated cell sorting and di...
Source: Experimental and Molecular Pathology - August 27, 2023 Category: Pathology Authors: Sherin Bakhashab Ghalya H Banafea Farid Ahmed Haneen Alsehli Huda F AlShaibi Nadia Bagatian Ohoud Subhi Kalamegam Gauthaman Mahmood Rasool Hans-Juergen Schulten Peter Natesan Pushparaj Source Type: research

Characterization of human umbilical cord blood-derived mast cells using high-throughput expression profiling and next-generation knowledge discovery platforms
Exp Mol Pathol. 2023 Aug 25:104867. doi: 10.1016/j.yexmp.2023.104867. Online ahead of print.ABSTRACTMast cells (MCs) are tissue-resident innate immune cells that express the high-affinity receptor for immunoglobulin E and are responsible for host defense and an array of diseases related to immune system. We aimed in this study to characterize the pathways and gene signatures of human cord blood-derived MCs (hCBMCs) in comparison to cells originating from CD34- progenitors using next-generation knowledge discovery methods. CD34+ cells were isolated from human umbilical cord blood using magnetic activated cell sorting and di...
Source: Experimental and Molecular Pathology - August 27, 2023 Category: Pathology Authors: Sherin Bakhashab Ghalya H Banafea Farid Ahmed Haneen Alsehli Huda F AlShaibi Nadia Bagatian Ohoud Subhi Kalamegam Gauthaman Mahmood Rasool Hans-Juergen Schulten Peter Natesan Pushparaj Source Type: research

Characterization of human umbilical cord blood-derived mast cells using high-throughput expression profiling and next-generation knowledge discovery platforms
Exp Mol Pathol. 2023 Aug 25:104867. doi: 10.1016/j.yexmp.2023.104867. Online ahead of print.ABSTRACTMast cells (MCs) are tissue-resident innate immune cells that express the high-affinity receptor for immunoglobulin E and are responsible for host defense and an array of diseases related to immune system. We aimed in this study to characterize the pathways and gene signatures of human cord blood-derived MCs (hCBMCs) in comparison to cells originating from CD34- progenitors using next-generation knowledge discovery methods. CD34+ cells were isolated from human umbilical cord blood using magnetic activated cell sorting and di...
Source: Experimental and Molecular Pathology - August 27, 2023 Category: Pathology Authors: Sherin Bakhashab Ghalya H Banafea Farid Ahmed Haneen Alsehli Huda F AlShaibi Nadia Bagatian Ohoud Subhi Kalamegam Gauthaman Mahmood Rasool Hans-Juergen Schulten Peter Natesan Pushparaj Source Type: research

A review of the critical role of vitamin D axis on the immune system
Exp Mol Pathol. 2023 Aug 17;132-133:104866. doi: 10.1016/j.yexmp.2023.104866. Online ahead of print.ABSTRACTIn recent years, the physiological and molecular functions of vitamin D (Vit-D) have been deeply investigated. At first, Vit-D was considered a regulator of mineral and skeletal homeostasis. However, due to the extensive-expression pattern of Vit-D receptor (VDR) in almost every non-skeletal cell, Vit-D is considered mainly a multifunctional agent with broad effects on various tissues, notably the immune system. The expression of VDR in immune cells such as dendritic cells, monocyte/macrophage, neutrophils, B cells a...
Source: Experimental and Molecular Pathology - August 12, 2023 Category: Pathology Authors: Gholamreza Daryabor Nasser Gholijani Fatemeh Rezaei Kahmini Source Type: research

A review of the critical role of vitamin D axis on the immune system
Exp Mol Pathol. 2023 Aug 17;132-133:104866. doi: 10.1016/j.yexmp.2023.104866. Online ahead of print.ABSTRACTIn recent years, the physiological and molecular functions of vitamin D (Vit-D) have been deeply investigated. At first, Vit-D was considered a regulator of mineral and skeletal homeostasis. However, due to the extensive-expression pattern of Vit-D receptor (VDR) in almost every non-skeletal cell, Vit-D is considered mainly a multifunctional agent with broad effects on various tissues, notably the immune system. The expression of VDR in immune cells such as dendritic cells, monocyte/macrophage, neutrophils, B cells a...
Source: Experimental and Molecular Pathology - August 12, 2023 Category: Pathology Authors: Gholamreza Daryabor Nasser Gholijani Fatemeh Rezaei Kahmini Source Type: research

A review of the critical role of vitamin D axis on the immune system
Exp Mol Pathol. 2023 Aug 17;132-133:104866. doi: 10.1016/j.yexmp.2023.104866. Online ahead of print.ABSTRACTIn recent years, the physiological and molecular functions of vitamin D (Vit-D) have been deeply investigated. At first, Vit-D was considered a regulator of mineral and skeletal homeostasis. However, due to the extensive-expression pattern of Vit-D receptor (VDR) in almost every non-skeletal cell, Vit-D is considered mainly a multifunctional agent with broad effects on various tissues, notably the immune system. The expression of VDR in immune cells such as dendritic cells, monocyte/macrophage, neutrophils, B cells a...
Source: Experimental and Molecular Pathology - August 12, 2023 Category: Pathology Authors: Gholamreza Daryabor Nasser Gholijani Fatemeh Rezaei Kahmini Source Type: research

A review of the critical role of vitamin D axis on the immune system
Exp Mol Pathol. 2023 Aug 17;132-133:104866. doi: 10.1016/j.yexmp.2023.104866. Online ahead of print.ABSTRACTIn recent years, the physiological and molecular functions of vitamin D (Vit-D) have been deeply investigated. At first, Vit-D was considered a regulator of mineral and skeletal homeostasis. However, due to the extensive-expression pattern of Vit-D receptor (VDR) in almost every non-skeletal cell, Vit-D is considered mainly a multifunctional agent with broad effects on various tissues, notably the immune system. The expression of VDR in immune cells such as dendritic cells, monocyte/macrophage, neutrophils, B cells a...
Source: Experimental and Molecular Pathology - August 12, 2023 Category: Pathology Authors: Gholamreza Daryabor Nasser Gholijani Fatemeh Rezaei Kahmini Source Type: research

A review of the critical role of vitamin D axis on the immune system
Exp Mol Pathol. 2023 Aug 17;132-133:104866. doi: 10.1016/j.yexmp.2023.104866. Online ahead of print.ABSTRACTIn recent years, the physiological and molecular functions of vitamin D (Vit-D) have been deeply investigated. At first, Vit-D was considered a regulator of mineral and skeletal homeostasis. However, due to the extensive-expression pattern of Vit-D receptor (VDR) in almost every non-skeletal cell, Vit-D is considered mainly a multifunctional agent with broad effects on various tissues, notably the immune system. The expression of VDR in immune cells such as dendritic cells, monocyte/macrophage, neutrophils, B cells a...
Source: Experimental and Molecular Pathology - August 12, 2023 Category: Pathology Authors: Gholamreza Daryabor Nasser Gholijani Fatemeh Rezaei Kahmini Source Type: research

A review of the critical role of vitamin D axis on the immune system
Exp Mol Pathol. 2023 Aug 17;132-133:104866. doi: 10.1016/j.yexmp.2023.104866. Online ahead of print.ABSTRACTIn recent years, the physiological and molecular functions of vitamin D (Vit-D) have been deeply investigated. At first, Vit-D was considered a regulator of mineral and skeletal homeostasis. However, due to the extensive-expression pattern of Vit-D receptor (VDR) in almost every non-skeletal cell, Vit-D is considered mainly a multifunctional agent with broad effects on various tissues, notably the immune system. The expression of VDR in immune cells such as dendritic cells, monocyte/macrophage, neutrophils, B cells a...
Source: Experimental and Molecular Pathology - August 12, 2023 Category: Pathology Authors: Gholamreza Daryabor Nasser Gholijani Fatemeh Rezaei Kahmini Source Type: research

A review of the critical role of vitamin D axis on the immune system
Exp Mol Pathol. 2023 Aug 17;132-133:104866. doi: 10.1016/j.yexmp.2023.104866. Online ahead of print.ABSTRACTIn recent years, the physiological and molecular functions of vitamin D (Vit-D) have been deeply investigated. At first, Vit-D was considered a regulator of mineral and skeletal homeostasis. However, due to the extensive-expression pattern of Vit-D receptor (VDR) in almost every non-skeletal cell, Vit-D is considered mainly a multifunctional agent with broad effects on various tissues, notably the immune system. The expression of VDR in immune cells such as dendritic cells, monocyte/macrophage, neutrophils, B cells a...
Source: Experimental and Molecular Pathology - August 12, 2023 Category: Pathology Authors: Gholamreza Daryabor Nasser Gholijani Fatemeh Rezaei Kahmini Source Type: research