Experimental and Molecular Pathology This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

A review of the critical role of vitamin D axis on the immune system
Exp Mol Pathol. 2023 Aug 10:104866. doi: 10.1016/j.yexmp.2023.104866. Online ahead of print.ABSTRACTIn recent years, the physiological and molecular functions of vitamin D (Vit-D) have been deeply investigated. At first, Vit-D was considered a regulator of mineral and skeletal homeostasis. However, due to the extensive-expression pattern of Vit-D receptor (VDR) in almost every non-skeletal cell, Vit-D is considered mainly a multifunctional agent with broad effects on various tissues, notably the immune system. The expression of VDR in immune cells such as dendritic cells, monocyte/macrophage, neutrophils, B cells and T cel...
Source: Experimental and Molecular Pathology - August 12, 2023 Category: Pathology Authors: Gholamreza Daryabor Nasser Gholijani Fatemeh Rezaei Kahmini Source Type: research

A review of the critical role of vitamin D axis on the immune system
Exp Mol Pathol. 2023 Aug 10:104866. doi: 10.1016/j.yexmp.2023.104866. Online ahead of print.ABSTRACTIn recent years, the physiological and molecular functions of vitamin D (Vit-D) have been deeply investigated. At first, Vit-D was considered a regulator of mineral and skeletal homeostasis. However, due to the extensive-expression pattern of Vit-D receptor (VDR) in almost every non-skeletal cell, Vit-D is considered mainly a multifunctional agent with broad effects on various tissues, notably the immune system. The expression of VDR in immune cells such as dendritic cells, monocyte/macrophage, neutrophils, B cells and T cel...
Source: Experimental and Molecular Pathology - August 12, 2023 Category: Pathology Authors: Gholamreza Daryabor Nasser Gholijani Fatemeh Rezaei Kahmini Source Type: research

A review of the critical role of vitamin D axis on the immune system
Exp Mol Pathol. 2023 Aug 10:104866. doi: 10.1016/j.yexmp.2023.104866. Online ahead of print.ABSTRACTIn recent years, the physiological and molecular functions of vitamin D (Vit-D) have been deeply investigated. At first, Vit-D was considered a regulator of mineral and skeletal homeostasis. However, due to the extensive-expression pattern of Vit-D receptor (VDR) in almost every non-skeletal cell, Vit-D is considered mainly a multifunctional agent with broad effects on various tissues, notably the immune system. The expression of VDR in immune cells such as dendritic cells, monocyte/macrophage, neutrophils, B cells and T cel...
Source: Experimental and Molecular Pathology - August 12, 2023 Category: Pathology Authors: Gholamreza Daryabor Nasser Gholijani Fatemeh Rezaei Kahmini Source Type: research

A review of the critical role of vitamin D axis on the immune system
Exp Mol Pathol. 2023 Aug 10:104866. doi: 10.1016/j.yexmp.2023.104866. Online ahead of print.ABSTRACTIn recent years, the physiological and molecular functions of vitamin D (Vit-D) have been deeply investigated. At first, Vit-D was considered a regulator of mineral and skeletal homeostasis. However, due to the extensive-expression pattern of Vit-D receptor (VDR) in almost every non-skeletal cell, Vit-D is considered mainly a multifunctional agent with broad effects on various tissues, notably the immune system. The expression of VDR in immune cells such as dendritic cells, monocyte/macrophage, neutrophils, B cells and T cel...
Source: Experimental and Molecular Pathology - August 12, 2023 Category: Pathology Authors: Gholamreza Daryabor Nasser Gholijani Fatemeh Rezaei Kahmini Source Type: research

A review of the critical role of vitamin D axis on the immune system
Exp Mol Pathol. 2023 Aug 10:104866. doi: 10.1016/j.yexmp.2023.104866. Online ahead of print.ABSTRACTIn recent years, the physiological and molecular functions of vitamin D (Vit-D) have been deeply investigated. At first, Vit-D was considered a regulator of mineral and skeletal homeostasis. However, due to the extensive-expression pattern of Vit-D receptor (VDR) in almost every non-skeletal cell, Vit-D is considered mainly a multifunctional agent with broad effects on various tissues, notably the immune system. The expression of VDR in immune cells such as dendritic cells, monocyte/macrophage, neutrophils, B cells and T cel...
Source: Experimental and Molecular Pathology - August 12, 2023 Category: Pathology Authors: Gholamreza Daryabor Nasser Gholijani Fatemeh Rezaei Kahmini Source Type: research

Epigenetic regulation of circ-HIPK3, circ-PVT1, miR-25, and miR-149 in radiosensitivity of breast cancer
Exp Mol Pathol. 2023 Aug 9;132-133:104865. doi: 10.1016/j.yexmp.2023.104865. Online ahead of print.ABSTRACTAssessing the radiosensitivity of cells before administering radiation therapy (RT) to individuals diagnosed with breast cancer (BC) can facilitate the selection of appropriate treatment regimens and minimize the incidence of adverse side effects in patients undergoing radiation exposure. In this research, blood samples were obtained from 60 women who had been diagnosed with Invasive Ductal Carcinoma (IDC) Breast Cancer. The average age of the patients was 47 ± 9.93. Additionally, the study incorporated 20 healthy wo...
Source: Experimental and Molecular Pathology - August 3, 2023 Category: Pathology Authors: Elahe Abdollahi Hossein Mozdarani Source Type: research

Epigenetic regulation of circ-HIPK3, circ-PVT1, miR-25, and miR-149 in radiosensitivity of breast cancer
Exp Mol Pathol. 2023 Aug 1:104865. doi: 10.1016/j.yexmp.2023.104865. Online ahead of print.ABSTRACTAssessing the radiosensitivity of cells before administering radiation therapy (RT) to individuals diagnosed with breast cancer (BC) can facilitate the selection of appropriate treatment regimens and minimize the incidence of adverse side effects in patients undergoing radiation exposure. In this research, blood samples were obtained from 60 women who had been diagnosed with Invasive Ductal Carcinoma (IDC) Breast Cancer. The average age of the patients was 47 ± 9.93. Additionally, the study incorporated 20 healthy women, wit...
Source: Experimental and Molecular Pathology - August 3, 2023 Category: Pathology Authors: Elahe Abdollahi Hossein Mozdarani Source Type: research

Epigenetic regulation of circ-HIPK3, circ-PVT1, miR-25, and miR-149 in radiosensitivity of breast cancer
Exp Mol Pathol. 2023 Aug 1:104865. doi: 10.1016/j.yexmp.2023.104865. Online ahead of print.ABSTRACTAssessing the radiosensitivity of cells before administering radiation therapy (RT) to individuals diagnosed with breast cancer (BC) can facilitate the selection of appropriate treatment regimens and minimize the incidence of adverse side effects in patients undergoing radiation exposure. In this research, blood samples were obtained from 60 women who had been diagnosed with Invasive Ductal Carcinoma (IDC) Breast Cancer. The average age of the patients was 47 ± 9.93. Additionally, the study incorporated 20 healthy women, wit...
Source: Experimental and Molecular Pathology - August 3, 2023 Category: Pathology Authors: Elahe Abdollahi Hossein Mozdarani Source Type: research

Epigenetic regulation of circ-HIPK3, circ-PVT1, miR-25, and miR-149 in radiosensitivity of breast cancer
Exp Mol Pathol. 2023 Aug 1:104865. doi: 10.1016/j.yexmp.2023.104865. Online ahead of print.ABSTRACTAssessing the radiosensitivity of cells before administering radiation therapy (RT) to individuals diagnosed with breast cancer (BC) can facilitate the selection of appropriate treatment regimens and minimize the incidence of adverse side effects in patients undergoing radiation exposure. In this research, blood samples were obtained from 60 women who had been diagnosed with Invasive Ductal Carcinoma (IDC) Breast Cancer. The average age of the patients was 47 ± 9.93. Additionally, the study incorporated 20 healthy women, wit...
Source: Experimental and Molecular Pathology - August 3, 2023 Category: Pathology Authors: Elahe Abdollahi Hossein Mozdarani Source Type: research

Epigenetic regulation of circ-HIPK3, circ-PVT1, miR-25, and miR-149 in radiosensitivity of breast cancer
Exp Mol Pathol. 2023 Aug 1:104865. doi: 10.1016/j.yexmp.2023.104865. Online ahead of print.ABSTRACTAssessing the radiosensitivity of cells before administering radiation therapy (RT) to individuals diagnosed with breast cancer (BC) can facilitate the selection of appropriate treatment regimens and minimize the incidence of adverse side effects in patients undergoing radiation exposure. In this research, blood samples were obtained from 60 women who had been diagnosed with Invasive Ductal Carcinoma (IDC) Breast Cancer. The average age of the patients was 47 ± 9.93. Additionally, the study incorporated 20 healthy women, wit...
Source: Experimental and Molecular Pathology - August 3, 2023 Category: Pathology Authors: Elahe Abdollahi Hossein Mozdarani Source Type: research

Epigenetic regulation of circ-HIPK3, circ-PVT1, miR-25, and miR-149 in radiosensitivity of breast cancer
Exp Mol Pathol. 2023 Aug 1:104865. doi: 10.1016/j.yexmp.2023.104865. Online ahead of print.ABSTRACTAssessing the radiosensitivity of cells before administering radiation therapy (RT) to individuals diagnosed with breast cancer (BC) can facilitate the selection of appropriate treatment regimens and minimize the incidence of adverse side effects in patients undergoing radiation exposure. In this research, blood samples were obtained from 60 women who had been diagnosed with Invasive Ductal Carcinoma (IDC) Breast Cancer. The average age of the patients was 47 ± 9.93. Additionally, the study incorporated 20 healthy women, wit...
Source: Experimental and Molecular Pathology - August 3, 2023 Category: Pathology Authors: Elahe Abdollahi Hossein Mozdarani Source Type: research

Epigenetic regulation of circ-HIPK3, circ-PVT1, miR-25, and miR-149 in radiosensitivity of breast cancer
Exp Mol Pathol. 2023 Aug 1:104865. doi: 10.1016/j.yexmp.2023.104865. Online ahead of print.ABSTRACTAssessing the radiosensitivity of cells before administering radiation therapy (RT) to individuals diagnosed with breast cancer (BC) can facilitate the selection of appropriate treatment regimens and minimize the incidence of adverse side effects in patients undergoing radiation exposure. In this research, blood samples were obtained from 60 women who had been diagnosed with Invasive Ductal Carcinoma (IDC) Breast Cancer. The average age of the patients was 47 ± 9.93. Additionally, the study incorporated 20 healthy women, wit...
Source: Experimental and Molecular Pathology - August 3, 2023 Category: Pathology Authors: Elahe Abdollahi Hossein Mozdarani Source Type: research

The biogenesis, biological functions and modification of Circular RNAs
Exp Mol Pathol. 2023 Jun;131:104861. doi: 10.1016/j.yexmp.2023.104861. Epub 2023 May 13.ABSTRACTCircular RNAs are covalently closed and non-coding in eukaryotes, which have tissue- specific and temporal-specific expression patterns whose biogenesis is regulated by transcription and splicing. Most circular RNAs are localized in the cytoplasm. The sequences and protein-binding elements of circular RNAs facilitate circular RNAs in exerting biological functions through complementary base pairing, regulating protein function or self-translation. Recent studies have revealed that N6-Methyladenosine (m6A), a prevalent post-transc...
Source: Experimental and Molecular Pathology - May 8, 2023 Category: Pathology Authors: Sen Liu Xiang Yu Guo Qing Juan Shang Peng Gao Source Type: research

The biogenesis, biological functions and modification of Circular RNAs
Exp Mol Pathol. 2023 Jun;131:104861. doi: 10.1016/j.yexmp.2023.104861. Epub 2023 May 13.ABSTRACTCircular RNAs are covalently closed and non-coding in eukaryotes, which have tissue- specific and temporal-specific expression patterns whose biogenesis is regulated by transcription and splicing. Most circular RNAs are localized in the cytoplasm. The sequences and protein-binding elements of circular RNAs facilitate circular RNAs in exerting biological functions through complementary base pairing, regulating protein function or self-translation. Recent studies have revealed that N6-Methyladenosine (m6A), a prevalent post-transc...
Source: Experimental and Molecular Pathology - May 8, 2023 Category: Pathology Authors: Sen Liu Xiang Yu Guo Qing Juan Shang Peng Gao Source Type: research

The biogenesis, biological functions and modification of Circular RNAs
Exp Mol Pathol. 2023 Jun;131:104861. doi: 10.1016/j.yexmp.2023.104861. Epub 2023 May 13.ABSTRACTCircular RNAs are covalently closed and non-coding in eukaryotes, which have tissue- specific and temporal-specific expression patterns whose biogenesis is regulated by transcription and splicing. Most circular RNAs are localized in the cytoplasm. The sequences and protein-binding elements of circular RNAs facilitate circular RNAs in exerting biological functions through complementary base pairing, regulating protein function or self-translation. Recent studies have revealed that N6-Methyladenosine (m6A), a prevalent post-transc...
Source: Experimental and Molecular Pathology - May 8, 2023 Category: Pathology Authors: Sen Liu Xiang Yu Guo Qing Juan Shang Peng Gao Source Type: research