TBX15 and SDHB expression changes in colorectal cancer serve as potential prognostic biomarkers
This study aimed to identify genes in colorectal cancer (CRC) that potentially serve as hub genes influencing patient survival rates. RNA-Seq data were downloaded from the cancer genome atlas database, and differential expression analysis was performed between tumors and healthy controls. Through the utilization of univariate and multivariate Cox regression analyses, in combination with the MCODE clustering module, the genes whose expression changes were related to survival rate and the hub genes related to them were identified. The mortality risk model was computed using the hub genes. CRC samples and the RT-qPCR method w...
Source: Experimental and Molecular Pathology - February 20, 2024 Category: Pathology Authors: Melika Golozar Ali Valipour Motlagh Mohammad Mahdevar Maryam Peymani Kolsoum InanlooRahatloo Kamran Ghaedi Source Type: research

TBX15 and SDHB expression changes in colorectal cancer serve as potential prognostic biomarkers
This study aimed to identify genes in colorectal cancer (CRC) that potentially serve as hub genes influencing patient survival rates. RNA-Seq data were downloaded from the cancer genome atlas database, and differential expression analysis was performed between tumors and healthy controls. Through the utilization of univariate and multivariate Cox regression analyses, in combination with the MCODE clustering module, the genes whose expression changes were related to survival rate and the hub genes related to them were identified. The mortality risk model was computed using the hub genes. CRC samples and the RT-qPCR method w...
Source: Experimental and Molecular Pathology - February 20, 2024 Category: Pathology Authors: Melika Golozar Ali Valipour Motlagh Mohammad Mahdevar Maryam Peymani Kolsoum InanlooRahatloo Kamran Ghaedi Source Type: research

TBX15 and SDHB expression changes in colorectal cancer serve as potential prognostic biomarkers
This study aimed to identify genes in colorectal cancer (CRC) that potentially serve as hub genes influencing patient survival rates. RNA-Seq data were downloaded from the cancer genome atlas database, and differential expression analysis was performed between tumors and healthy controls. Through the utilization of univariate and multivariate Cox regression analyses, in combination with the MCODE clustering module, the genes whose expression changes were related to survival rate and the hub genes related to them were identified. The mortality risk model was computed using the hub genes. CRC samples and the RT-qPCR method w...
Source: Experimental and Molecular Pathology - February 20, 2024 Category: Pathology Authors: Melika Golozar Ali Valipour Motlagh Mohammad Mahdevar Maryam Peymani Kolsoum InanlooRahatloo Kamran Ghaedi Source Type: research

TBX15 and SDHB expression changes in colorectal cancer serve as potential prognostic biomarkers
This study aimed to identify genes in colorectal cancer (CRC) that potentially serve as hub genes influencing patient survival rates. RNA-Seq data were downloaded from the cancer genome atlas database, and differential expression analysis was performed between tumors and healthy controls. Through the utilization of univariate and multivariate Cox regression analyses, in combination with the MCODE clustering module, the genes whose expression changes were related to survival rate and the hub genes related to them were identified. The mortality risk model was computed using the hub genes. CRC samples and the RT-qPCR method w...
Source: Experimental and Molecular Pathology - February 20, 2024 Category: Pathology Authors: Melika Golozar Ali Valipour Motlagh Mohammad Mahdevar Maryam Peymani Kolsoum InanlooRahatloo Kamran Ghaedi Source Type: research

TBX15 and SDHB expression changes in colorectal cancer serve as potential prognostic biomarkers
This study aimed to identify genes in colorectal cancer (CRC) that potentially serve as hub genes influencing patient survival rates. RNA-Seq data were downloaded from the cancer genome atlas database, and differential expression analysis was performed between tumors and healthy controls. Through the utilization of univariate and multivariate Cox regression analyses, in combination with the MCODE clustering module, the genes whose expression changes were related to survival rate and the hub genes related to them were identified. The mortality risk model was computed using the hub genes. CRC samples and the RT-qPCR method w...
Source: Experimental and Molecular Pathology - February 20, 2024 Category: Pathology Authors: Melika Golozar Ali Valipour Motlagh Mohammad Mahdevar Maryam Peymani Kolsoum InanlooRahatloo Kamran Ghaedi Source Type: research

TBX15 and SDHB expression changes in colorectal cancer serve as potential prognostic biomarkers
This study aimed to identify genes in colorectal cancer (CRC) that potentially serve as hub genes influencing patient survival rates. RNA-Seq data were downloaded from the cancer genome atlas database, and differential expression analysis was performed between tumors and healthy controls. Through the utilization of univariate and multivariate Cox regression analyses, in combination with the MCODE clustering module, the genes whose expression changes were related to survival rate and the hub genes related to them were identified. The mortality risk model was computed using the hub genes. CRC samples and the RT-qPCR method w...
Source: Experimental and Molecular Pathology - February 20, 2024 Category: Pathology Authors: Melika Golozar Ali Valipour Motlagh Mohammad Mahdevar Maryam Peymani Kolsoum InanlooRahatloo Kamran Ghaedi Source Type: research

TBX15 and SDHB expression changes in colorectal cancer serve as potential prognostic biomarkers
This study aimed to identify genes in colorectal cancer (CRC) that potentially serve as hub genes influencing patient survival rates. RNA-Seq data were downloaded from the cancer genome atlas database, and differential expression analysis was performed between tumors and healthy controls. Through the utilization of univariate and multivariate Cox regression analyses, in combination with the MCODE clustering module, the genes whose expression changes were related to survival rate and the hub genes related to them were identified. The mortality risk model was computed using the hub genes. CRC samples and the RT-qPCR method w...
Source: Experimental and Molecular Pathology - February 20, 2024 Category: Pathology Authors: Melika Golozar Ali Valipour Motlagh Mohammad Mahdevar Maryam Peymani Kolsoum InanlooRahatloo Kamran Ghaedi Source Type: research

TBX15 and SDHB expression changes in colorectal cancer serve as potential prognostic biomarkers
This study aimed to identify genes in colorectal cancer (CRC) that potentially serve as hub genes influencing patient survival rates. RNA-Seq data were downloaded from the cancer genome atlas database, and differential expression analysis was performed between tumors and healthy controls. Through the utilization of univariate and multivariate Cox regression analyses, in combination with the MCODE clustering module, the genes whose expression changes were related to survival rate and the hub genes related to them were identified. The mortality risk model was computed using the hub genes. CRC samples and the RT-qPCR method w...
Source: Experimental and Molecular Pathology - February 20, 2024 Category: Pathology Authors: Melika Golozar Ali Valipour Motlagh Mohammad Mahdevar Maryam Peymani Kolsoum InanlooRahatloo Kamran Ghaedi Source Type: research

TBX15 and SDHB expression changes in colorectal cancer serve as potential prognostic biomarkers
This study aimed to identify genes in colorectal cancer (CRC) that potentially serve as hub genes influencing patient survival rates. RNA-Seq data were downloaded from the cancer genome atlas database, and differential expression analysis was performed between tumors and healthy controls. Through the utilization of univariate and multivariate Cox regression analyses, in combination with the MCODE clustering module, the genes whose expression changes were related to survival rate and the hub genes related to them were identified. The mortality risk model was computed using the hub genes. CRC samples and the RT-qPCR method w...
Source: Experimental and Molecular Pathology - February 20, 2024 Category: Pathology Authors: Melika Golozar Ali Valipour Motlagh Mohammad Mahdevar Maryam Peymani Kolsoum InanlooRahatloo Kamran Ghaedi Source Type: research

TBX15 and SDHB expression changes in colorectal cancer serve as potential prognostic biomarkers
This study aimed to identify genes in colorectal cancer (CRC) that potentially serve as hub genes influencing patient survival rates. RNA-Seq data were downloaded from the cancer genome atlas database, and differential expression analysis was performed between tumors and healthy controls. Through the utilization of univariate and multivariate Cox regression analyses, in combination with the MCODE clustering module, the genes whose expression changes were related to survival rate and the hub genes related to them were identified. The mortality risk model was computed using the hub genes. CRC samples and the RT-qPCR method w...
Source: Experimental and Molecular Pathology - February 20, 2024 Category: Pathology Authors: Melika Golozar Ali Valipour Motlagh Mohammad Mahdevar Maryam Peymani Kolsoum InanlooRahatloo Kamran Ghaedi Source Type: research

TBX15 and SDHB expression changes in colorectal cancer serve as potential prognostic biomarkers
This study aimed to identify genes in colorectal cancer (CRC) that potentially serve as hub genes influencing patient survival rates. RNA-Seq data were downloaded from the cancer genome atlas database, and differential expression analysis was performed between tumors and healthy controls. Through the utilization of univariate and multivariate Cox regression analyses, in combination with the MCODE clustering module, the genes whose expression changes were related to survival rate and the hub genes related to them were identified. The mortality risk model was computed using the hub genes. CRC samples and the RT-qPCR method w...
Source: Experimental and Molecular Pathology - February 20, 2024 Category: Pathology Authors: Melika Golozar Ali Valipour Motlagh Mohammad Mahdevar Maryam Peymani Kolsoum InanlooRahatloo Kamran Ghaedi Source Type: research

TBX15 and SDHB expression changes in colorectal cancer serve as potential prognostic biomarkers
This study aimed to identify genes in colorectal cancer (CRC) that potentially serve as hub genes influencing patient survival rates. RNA-Seq data were downloaded from the cancer genome atlas database, and differential expression analysis was performed between tumors and healthy controls. Through the utilization of univariate and multivariate Cox regression analyses, in combination with the MCODE clustering module, the genes whose expression changes were related to survival rate and the hub genes related to them were identified. The mortality risk model was computed using the hub genes. CRC samples and the RT-qPCR method w...
Source: Experimental and Molecular Pathology - February 20, 2024 Category: Pathology Authors: Melika Golozar Ali Valipour Motlagh Mohammad Mahdevar Maryam Peymani Kolsoum InanlooRahatloo Kamran Ghaedi Source Type: research

TBX15 and SDHB expression changes in colorectal cancer serve as potential prognostic biomarkers
This study aimed to identify genes in colorectal cancer (CRC) that potentially serve as hub genes influencing patient survival rates. RNA-Seq data were downloaded from the cancer genome atlas database, and differential expression analysis was performed between tumors and healthy controls. Through the utilization of univariate and multivariate Cox regression analyses, in combination with the MCODE clustering module, the genes whose expression changes were related to survival rate and the hub genes related to them were identified. The mortality risk model was computed using the hub genes. CRC samples and the RT-qPCR method w...
Source: Experimental and Molecular Pathology - February 20, 2024 Category: Pathology Authors: Melika Golozar Ali Valipour Motlagh Mohammad Mahdevar Maryam Peymani Kolsoum InanlooRahatloo Kamran Ghaedi Source Type: research

TBX15 and SDHB expression changes in colorectal cancer serve as potential prognostic biomarkers
This study aimed to identify genes in colorectal cancer (CRC) that potentially serve as hub genes influencing patient survival rates. RNA-Seq data were downloaded from the cancer genome atlas database, and differential expression analysis was performed between tumors and healthy controls. Through the utilization of univariate and multivariate Cox regression analyses, in combination with the MCODE clustering module, the genes whose expression changes were related to survival rate and the hub genes related to them were identified. The mortality risk model was computed using the hub genes. CRC samples and the RT-qPCR method w...
Source: Experimental and Molecular Pathology - February 20, 2024 Category: Pathology Authors: Melika Golozar Ali Valipour Motlagh Mohammad Mahdevar Maryam Peymani Kolsoum InanlooRahatloo Kamran Ghaedi Source Type: research

Molecular and cellular pruritus mechanisms in the host skin
Exp Mol Pathol. 2024 Feb 6;136:104889. doi: 10.1016/j.yexmp.2024.104889. Online ahead of print.ABSTRACTPruritus, also known as itching, is a complex sensation that involves the activation of specific physiological and cellular receptors. The skin is innervated with sensory nerves as well as some receptors for various sensations, and its immune system has prominent neurological connections. Sensory neurons have a considerable impact on the sensation of itching. However, immune cells also play a role in this process, as they release pruritogens. Disruption of the dermal barrier activates an immune response, initiating a seri...
Source: Experimental and Molecular Pathology - February 5, 2024 Category: Pathology Authors: Li Li Zhi-En Li Yun-Li Mo Wan-Yao Li Hui-Jing Li Guang-Hai Yan Xiang-Zheng Qin Li-Hua Piao Source Type: research