Childhood-onset epilepsy in patients with dyskinetic cerebral palsy caused by basal ganglia and thalamic lesions
CONCLUSIONS: One-third of term-born patients with BGTL-induced DCP caused by perinatal HIE develop epilepsy, and deep white matter lesions increase the likelihood of epilepsy. Preparation for early-onset ES, MS, and subsequent FS is beneficial.PMID:37708783 | DOI:10.1016/j.ejpn.2023.09.006 (Source: European Journal of Paediatric Neurology)
Source: European Journal of Paediatric Neurology - September 14, 2023 Category: Neurology Authors: Shizuka Nishimoto Yukihiro Kitai Satori Hirai Mika Hirotsune Naomi Okuyama Shodo Hirano Yukiko Mogami Hiroshi Arai Source Type: research

Assessing communication, beyond just words
Eur J Paediatr Neurol. 2023 Sep 9:S1090-3798(23)00135-6. doi: 10.1016/j.ejpn.2023.09.002. Online ahead of print.NO ABSTRACTPMID:37709641 | DOI:10.1016/j.ejpn.2023.09.002 (Source: European Journal of Paediatric Neurology)
Source: European Journal of Paediatric Neurology - September 14, 2023 Category: Neurology Authors: Kimberly Goodspeed Source Type: research

Characterizing, classifying, and collecting spells in paroxysmal disorders - A need as targeted therapies approach for childhood neurological disorders
Eur J Paediatr Neurol. 2023 Sep 9:S1090-3798(23)00136-8. doi: 10.1016/j.ejpn.2023.09.003. Online ahead of print.NO ABSTRACTPMID:37704551 | DOI:10.1016/j.ejpn.2023.09.003 (Source: European Journal of Paediatric Neurology)
Source: European Journal of Paediatric Neurology - September 13, 2023 Category: Neurology Authors: Phillip L Pearl Source Type: research

Characterizing, classifying, and collecting spells in paroxysmal disorders - A need as targeted therapies approach for childhood neurological disorders
Eur J Paediatr Neurol. 2023 Sep 9:S1090-3798(23)00136-8. doi: 10.1016/j.ejpn.2023.09.003. Online ahead of print.NO ABSTRACTPMID:37704551 | DOI:10.1016/j.ejpn.2023.09.003 (Source: European Journal of Paediatric Neurology)
Source: European Journal of Paediatric Neurology - September 13, 2023 Category: Neurology Authors: Phillip L Pearl Source Type: research

An adapted clinical global Impression of improvement for use in Angelman syndrome: Validation analyses utilizing data from the NEPTUNE study
CONCLUSIONS: Our validation analysis of the CGI-I-AS demonstrates its usefulness along with possible areas of improvement. The CGI-I-AS is a potential tool for use in other trials of AS drug candidates, and the process for its development can serve as a road map for the development of assessment tools for other neuropsychiatric disorders with similar complexities and heterogeneity.PMID:37688937 | DOI:10.1016/j.ejpn.2023.08.003 (Source: European Journal of Paediatric Neurology)
Source: European Journal of Paediatric Neurology - September 9, 2023 Category: Neurology Authors: Pamela Ventola Judith Jaeger Christopher J Keary Alexander Kolevzon Maxwell Adams Bina Keshavan Celia Zinger-Salmun Cesar Ochoa-Lubinoff Source Type: research

An adapted clinical global Impression of improvement for use in Angelman syndrome: Validation analyses utilizing data from the NEPTUNE study
CONCLUSIONS: Our validation analysis of the CGI-I-AS demonstrates its usefulness along with possible areas of improvement. The CGI-I-AS is a potential tool for use in other trials of AS drug candidates, and the process for its development can serve as a road map for the development of assessment tools for other neuropsychiatric disorders with similar complexities and heterogeneity.PMID:37688937 | DOI:10.1016/j.ejpn.2023.08.003 (Source: European Journal of Paediatric Neurology)
Source: European Journal of Paediatric Neurology - September 9, 2023 Category: Neurology Authors: Pamela Ventola Judith Jaeger Christopher J Keary Alexander Kolevzon Maxwell Adams Bina Keshavan Celia Zinger-Salmun Cesar Ochoa-Lubinoff Source Type: research

An adapted clinical global Impression of improvement for use in Angelman syndrome: Validation analyses utilizing data from the NEPTUNE study
CONCLUSIONS: Our validation analysis of the CGI-I-AS demonstrates its usefulness along with possible areas of improvement. The CGI-I-AS is a potential tool for use in other trials of AS drug candidates, and the process for its development can serve as a road map for the development of assessment tools for other neuropsychiatric disorders with similar complexities and heterogeneity.PMID:37688937 | DOI:10.1016/j.ejpn.2023.08.003 (Source: European Journal of Paediatric Neurology)
Source: European Journal of Paediatric Neurology - September 9, 2023 Category: Neurology Authors: Pamela Ventola Judith Jaeger Christopher J Keary Alexander Kolevzon Maxwell Adams Bina Keshavan Celia Zinger-Salmun Cesar Ochoa-Lubinoff Source Type: research

An adapted clinical global Impression of improvement for use in Angelman syndrome: Validation analyses utilizing data from the NEPTUNE study
CONCLUSIONS: Our validation analysis of the CGI-I-AS demonstrates its usefulness along with possible areas of improvement. The CGI-I-AS is a potential tool for use in other trials of AS drug candidates, and the process for its development can serve as a road map for the development of assessment tools for other neuropsychiatric disorders with similar complexities and heterogeneity.PMID:37688937 | DOI:10.1016/j.ejpn.2023.08.003 (Source: European Journal of Paediatric Neurology)
Source: European Journal of Paediatric Neurology - September 9, 2023 Category: Neurology Authors: Pamela Ventola Judith Jaeger Christopher J Keary Alexander Kolevzon Maxwell Adams Bina Keshavan Celia Zinger-Salmun Cesar Ochoa-Lubinoff Source Type: research

Updated clinical recommendations for the management of tuberous sclerosis complex associated epilepsy
Eur J Paediatr Neurol. 2023 Aug 30;47:25-34. doi: 10.1016/j.ejpn.2023.08.005. Online ahead of print.ABSTRACTChildren with tuberous sclerosis complex (TSC), may experience a variety of seizure types in the first year of life, most often focal seizure sand epileptic spasms. Drug resistance is seen early in many patients, and the management of TSC associated epilepsy remain a major challenge for clinicians. In 2018 clinical recommendations for the management of TSC associated epilepsy were published by a panel of European experts. In the last five years considerable progress has been made in understanding the neurobiology of ...
Source: European Journal of Paediatric Neurology - September 5, 2023 Category: Neurology Authors: Nicola Specchio Rima Nabbout Eleonora Aronica Stephane Auvin Arianna Benvenuto Luca de Palma Martha Feucht Floor Jansen Katarzyna Kotulska Harvey Sarnat Lieven Lagae Sergiusz Jozwiak Paolo Curatolo Source Type: research

Updated clinical recommendations for the management of tuberous sclerosis complex associated epilepsy
Eur J Paediatr Neurol. 2023 Aug 30;47:25-34. doi: 10.1016/j.ejpn.2023.08.005. Online ahead of print.ABSTRACTChildren with tuberous sclerosis complex (TSC), may experience a variety of seizure types in the first year of life, most often focal seizure sand epileptic spasms. Drug resistance is seen early in many patients, and the management of TSC associated epilepsy remain a major challenge for clinicians. In 2018 clinical recommendations for the management of TSC associated epilepsy were published by a panel of European experts. In the last five years considerable progress has been made in understanding the neurobiology of ...
Source: European Journal of Paediatric Neurology - September 5, 2023 Category: Neurology Authors: Nicola Specchio Rima Nabbout Eleonora Aronica Stephane Auvin Arianna Benvenuto Luca de Palma Martha Feucht Floor Jansen Katarzyna Kotulska Harvey Sarnat Lieven Lagae Sergiusz Jozwiak Paolo Curatolo Source Type: research

Updated clinical recommendations for the management of tuberous sclerosis complex associated epilepsy
Eur J Paediatr Neurol. 2023 Aug 30;47:25-34. doi: 10.1016/j.ejpn.2023.08.005. Online ahead of print.ABSTRACTChildren with tuberous sclerosis complex (TSC), may experience a variety of seizure types in the first year of life, most often focal seizure sand epileptic spasms. Drug resistance is seen early in many patients, and the management of TSC associated epilepsy remain a major challenge for clinicians. In 2018 clinical recommendations for the management of TSC associated epilepsy were published by a panel of European experts. In the last five years considerable progress has been made in understanding the neurobiology of ...
Source: European Journal of Paediatric Neurology - September 5, 2023 Category: Neurology Authors: Nicola Specchio Rima Nabbout Eleonora Aronica Stephane Auvin Arianna Benvenuto Luca de Palma Martha Feucht Floor Jansen Katarzyna Kotulska Harvey Sarnat Lieven Lagae Sergiusz Jozwiak Paolo Curatolo Source Type: research

Updated clinical recommendations for the management of tuberous sclerosis complex associated epilepsy
Eur J Paediatr Neurol. 2023 Aug 30;47:25-34. doi: 10.1016/j.ejpn.2023.08.005. Online ahead of print.ABSTRACTChildren with tuberous sclerosis complex (TSC), may experience a variety of seizure types in the first year of life, most often focal seizure sand epileptic spasms. Drug resistance is seen early in many patients, and the management of TSC associated epilepsy remain a major challenge for clinicians. In 2018 clinical recommendations for the management of TSC associated epilepsy were published by a panel of European experts. In the last five years considerable progress has been made in understanding the neurobiology of ...
Source: European Journal of Paediatric Neurology - September 5, 2023 Category: Neurology Authors: Nicola Specchio Rima Nabbout Eleonora Aronica Stephane Auvin Arianna Benvenuto Luca de Palma Martha Feucht Floor Jansen Katarzyna Kotulska Harvey Sarnat Lieven Lagae Sergiusz Jozwiak Paolo Curatolo Source Type: research

A reappraisal of interictal EEG characteristics in self-limited epilepsy with autonomic seizures, formerly known as Panayiotopoulos syndrome or early-onset benign occipital epilepsy
CONCLUSION: Interictal EEG foci in SeLAES may have different EEG patterns in terms of location and the mode of appearance depending on the age at which EEG is recorded. O-Fp EEG foci may be a specific EEG pattern indicating a diagnosis of SeLEAS.PMID:37660659 | DOI:10.1016/j.ejpn.2023.08.004 (Source: European Journal of Paediatric Neurology)
Source: European Journal of Paediatric Neurology - September 3, 2023 Category: Neurology Authors: Hirokazu Oguni Source Type: research

A reappraisal of interictal EEG characteristics in self-limited epilepsy with autonomic seizures, formerly known as Panayiotopoulos syndrome or early-onset benign occipital epilepsy
CONCLUSION: Interictal EEG foci in SeLAES may have different EEG patterns in terms of location and the mode of appearance depending on the age at which EEG is recorded. O-Fp EEG foci may be a specific EEG pattern indicating a diagnosis of SeLEAS.PMID:37660659 | DOI:10.1016/j.ejpn.2023.08.004 (Source: European Journal of Paediatric Neurology)
Source: European Journal of Paediatric Neurology - September 3, 2023 Category: Neurology Authors: Hirokazu Oguni Source Type: research

Knowledge, awareness, and attitudes towards epilepsy among elementary schoolteachers in the Kingdom of Bahrain
CONCLUSION: The knowledge and attitudes of schoolteachers in Bahrain towards epilepsy are relatively good but with remaining improvement potential. They do not fully grasp all seizure types nor adequate first-aid measures promoting future epilepsy educational programs.PMID:37659186 | DOI:10.1016/j.ejpn.2023.08.001 (Source: European Journal of Paediatric Neurology)
Source: European Journal of Paediatric Neurology - September 2, 2023 Category: Neurology Authors: Alaa Elmazny Salman Alzayani Mohamed Hany Shehata Rehab Magdy Source Type: research